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Aliases for C19orf43 Gene

Aliases for C19orf43 Gene

  • Chromosome 19 Open Reading Frame 43 2 3 5
  • Functional Spliceosome-Associated Protein 18 2
  • My029 Protein 3
  • FSAP18 3

External Ids for C19orf43 Gene

Previous GeneCards Identifiers for C19orf43 Gene

  • GC19M012703
  • GC19M012841
  • GC19M012414

Summaries for C19orf43 Gene

GeneCards Summary for C19orf43 Gene

C19orf43 (Chromosome 19 Open Reading Frame 43) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf43 Gene

Genomics for C19orf43 Gene

Regulatory Elements for C19orf43 Gene

Promoters for C19orf43 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C19orf43 on UCSC Golden Path with GeneCards custom track

Genomic Location for C19orf43 Gene

Chromosome:
19
Start:
12,730,640 bp from pter
End:
12,734,775 bp from pter
Size:
4,136 bases
Orientation:
Minus strand

Genomic View for C19orf43 Gene

Genes around C19orf43 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf43 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf43 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf43 Gene

Proteins for C19orf43 Gene

  • Protein details for C19orf43 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BQ61-CS043_HUMAN
    Recommended name:
    Uncharacterized protein C19orf43
    Protein Accession:
    Q9BQ61

    Protein attributes for C19orf43 Gene

    Size:
    176 amino acids
    Molecular mass:
    18419 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C19orf43 Gene

Proteomics data for C19orf43 Gene at MOPED

Post-translational modifications for C19orf43 Gene

  • Ubiquitination at Lys 152
  • Modification sites at PhosphoSitePlus

Other Protein References for C19orf43 Gene

No data available for DME Specific Peptides for C19orf43 Gene

Domains & Families for C19orf43 Gene

Protein Domains for C19orf43 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C19orf43: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf43 Gene

Function for C19orf43 Gene

genes like me logo Genes that share phenotypes with C19orf43: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf43 Gene

Localization for C19orf43 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C19orf43 Gene COMPARTMENTS Subcellular localization image for C19orf43 gene
Compartment Confidence
nucleus 3
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf43 Gene

Pathways & Interactions for C19orf43 Gene

SuperPathways for C19orf43 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C19orf43 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C19orf43 Gene

Drugs & Compounds for C19orf43 Gene

No Compound Related Data Available

Transcripts for C19orf43 Gene

Unigene Clusters for C19orf43 Gene

Chromosome 19 open reading frame 43:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf43 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b
SP1: -
SP2:

Relevant External Links for C19orf43 Gene

GeneLoc Exon Structure for
C19orf43
ECgene alternative splicing isoforms for
C19orf43

Expression for C19orf43 Gene

mRNA expression in normal human tissues for C19orf43 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C19orf43 Gene

This gene is overexpressed in Nasal epithelium (12.4), Peripheral blood mononuclear cells (11.0), Breast (9.1), and Tlymphocyte (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C19orf43 Gene



SOURCE GeneReport for Unigene cluster for C19orf43 Gene Hs.515155

genes like me logo Genes that share expression patterns with C19orf43: view

Protein tissue co-expression partners for C19orf43 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C19orf43 Gene

Orthologs for C19orf43 Gene

This gene was present in the common ancestor of animals.

Orthologs for C19orf43 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C7H19orf43 35
  • 93.56 (n)
  • 96.59 (a)
C7H19orf43 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C20H19orf43 35
  • 93.18 (n)
  • 96.02 (a)
C19orf43 36
  • 67 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2310036O22Rik 35
  • 92.05 (n)
  • 94.19 (a)
2310036O22Rik 16
2310036O22Rik 36
  • 94 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf43 35
  • 100 (n)
  • 100 (a)
C19orf43 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1564093 35
  • 91.28 (n)
  • 93.6 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 70 (a)
OneToMany
-- 36
  • 71 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia C19orf43 36
  • 65 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.528 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.6514 35
zebrafish
(Danio rerio)
Actinopterygii Dr.15916 35
LOC560758 35
  • 56.77 (n)
  • 52.73 (a)
C3H19orf43 36
  • 46 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG18809 36
  • 18 (a)
OneToOne
Species with no ortholog for C19orf43:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C19orf43 Gene

ENSEMBL:
Gene Tree for C19orf43 (if available)
TreeFam:
Gene Tree for C19orf43 (if available)

Paralogs for C19orf43 Gene

No data available for Paralogs for C19orf43 Gene

Variants for C19orf43 Gene

Sequence variations from dbSNP and Humsavar for C19orf43 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1052589 -- 12,730,671(-) CACTT(C/T)TGGGA utr-variant-3-prime
rs8100789 -- 12,733,207(+) cccAA(C/T)CCACG intron-variant
rs10420261 -- 12,731,584(+) GCACA(C/T)GCGAC intron-variant
rs10420318 -- 12,731,675(+) ACTTT(C/T)CACGC intron-variant
rs11542950 -- 12,733,173(-) CCAAC(A/T)TTTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C19orf43 Gene

Variant ID Type Subtype PubMed ID
dgv3733n71 CNV Loss 21882294
nsv911077 CNV Loss 21882294

Variation tolerance for C19orf43 Gene

Gene Damage Index Score: 0.11; 2.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C19orf43 Gene

HapMap Linkage Disequilibrium report
C19orf43

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf43 Gene

Disorders for C19orf43 Gene

Relevant External Links for C19orf43

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C19orf43

No disorders were found for C19orf43 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf43 Gene

Publications for C19orf43 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  4. Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis. (PMID: 24657165) Kim H. … D'Andrea A.D. (Mol. Cell 2014) 3
  5. Dynamic protein-protein interaction wiring of the human spliceosome. (PMID: 22365833) Hegele A. … Stelzl U. (Mol. Cell 2012) 3

Products for C19orf43 Gene

Sources for C19orf43 Gene

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