C19orf43 Gene
protein-coding GIFtS: 39
GCID: GC19M012841 (predicted)
|
|
chromosome 19 open reading frame 43
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Aliases
for C19orf43 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 19 Open Reading Frame 431 2 | | FSAP181 | | MGC28031 | | My029 Protein2 | | Uncharacterized Protein C19orf432 |
Export aliases for C19orf43 gene to outside databasesPrevious GC identifers: GC19M012703 GC19M012414 |
Summaries
for C19orf43 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C19orf43 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C19orf43 gene promoter:
ER-alpha Pax-5 Sp1 GCNF Pax-6 Nkx2-5 AP-2gamma Tal-1beta GCNF-1 ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for C19orf43
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C19orf43 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.2 Ensembl cytogenetic band: 19p13.2 HGNC cytogenetic band: 19p13.2C19orf43 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M012841: view genomic region
(about GC identifiers)
Start:
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12,841,454 bp from pter |
End:
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12,845,589 bp from pter |
Size:
|
4,136 bases |
Orientation:
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minus strand |
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Proteins
for C19orf43 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CS043_HUMAN, Q9BQ61 (See
protein sequence)Recommended Name: Uncharacterized protein C19orf43 Size: 176 amino acids; 18419 DaExplore the universe of human proteins at neXtProt for C19orf43: NX_Q9BQ61
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BQ61
C19orf43 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_076943.1
ENSEMBL proteins: ENSP00000468415 ENSP00000466801 ENSP00000242784 ENSP00000466196
Human Recombinant Protein Products:
C19orf43 Antibody Products:
Assay Products for C19orf43: |
Protein
Domains /
Families
for C19orf43 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9BQ61 |
Function
for C19orf43 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf43 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf43
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C19orf43 (NM_024038) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C19orf43 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C19orf43 |
1 GenomeRNAi human phenotype for C19orf43:
|
Pathways & Interactions
for C19orf43 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C19orf43
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
3 Interacting proteins for C19orf43 (Q9BQ612, 3 ENSP000002427844) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C19orf43 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C19orf43
Search CenterWatch for drugs/clinical trials and news about C19orf43 / CS043
|
Transcripts
for C19orf43 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C19orf43 gene: NM_024038.2 Unigene Cluster for C19orf43: Chromosome 19 open reading frame 43 Hs.515155 [show with all ESTs]Unigene Representative Sequence: BC0408465 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000591254 ENST00000592273 ENST00000242784(uc002muu.3) ENST00000588213
ENST00000589590
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf43 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf43
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C19orf43 (NM_024038) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C19orf43 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C19orf43 |
Additional cDNA sequence: AF061732.1 AK027588.1 AK315754.1 BC000216.2 BC004533.2 BC015347.1 BC040846.1 11 DOTS entries: DT.452270 DT.40119243 DT.91889962 DT.92440358 DT.92466283 DT.100773096 DT.100836410 DT.100861944 DT.100038128 DT.121502880 DT.91960003 24/416 AceView cDNA sequences (see all 416): BQ574732 BM974872 BQ669375 BU159896 CF128151 BG754070 BE464547 BM761312 CD109041 BI522115 AA781178 BQ675320 AI460181 AW406442 BQ774345 AI282190 AA418114 AI831040 CR621512 AI695095 NM_024038 CR605443 BU857117 BM742410
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for C19orf43 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b |
|---|
|
| SP1: | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | |
ECgene alternative splicing isoforms for C19orf43
|
Expression
for C19orf43 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C19orf43 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCTGGGACT
About this image
See C19orf43 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C19orf43
SOURCE GeneReport for Unigene cluster: Hs.515155
SABiosciences Custom PCR Arrays for C19orf43
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C19orf43
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat C19orf43 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C19orf43 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C19orf43 |
Orthologs
for C19orf43 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for C19orf43 gene from 5/13 species (see all 13) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
2310036O22Rik1 , 5 |
RIKEN cDNA 2310036O22 gene1, 5 |
92.05(n)1
94.19(a)1 |
|
8 (41.49 cM)5
685441 NM_026760.21 NP_081036.21
850268335 |
lizard
(Anolis carolinensis) |
Reptilia |
C19orf436 |
-- |
66(a) |
1 ↔ 1 |
GL343286.1(835325-840735) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.65142 |
Xenopus laevis transcribed sequence with weak similarity more |
79.8(n) |
|
BJ034808.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.159162 |
Transcribed sequence with weak similarity to protein more |
83.97(n) |
|
AL911861.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG188096 |
-- |
14(a) |
1 ↔ 1 |
X(19635257-19638371) |
ENSEMBL Gene Tree for C19orf43 (if available)
TreeFam Gene Tree for C19orf43 (if available) |
Paralogs
for C19orf43 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C19orf43 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C19orf43 (12841454 - 12845589 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C19orf43: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C19orf43 |
|
Disorders
/ Diseases
for C19orf43 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C19orf43 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C19orf43 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with C19orf43) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
- Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. (PubMed id 17332742)1 Behzadnia N.... Luehrmann R. (2007)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
|
External Searches for C19orf43 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C19orf43 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C19orf43 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C19orf43 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C19orf43 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C19orf43 gene:
Search GeneIP for patents involving C19orf43
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C19orf43 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C19orf43 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C19orf43 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C19orf43 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C19orf43 | | OriGene 3'-UTR Clone for C19orf43 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf43 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf43 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C19orf43 | | OriGene Custom Protein Services for C19orf43 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C19orf43 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C19orf43 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C19orf43 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C19orf43 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C19orf43 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C19orf43 |
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 | | | C19orf43 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for C19orf43 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C19orf43 |
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