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Aliases for C19orf43 Gene

Aliases for C19orf43 Gene

  • Chromosome 19 Open Reading Frame 43 2 3 5
  • Functional Spliceosome-Associated Protein 18 2
  • Uncharacterized Protein C19orf43 3
  • My029 Protein 3
  • FSAP18 3

External Ids for C19orf43 Gene

Previous GeneCards Identifiers for C19orf43 Gene

  • GC19M012703
  • GC19M012841
  • GC19M012414

Summaries for C19orf43 Gene

GeneCards Summary for C19orf43 Gene

C19orf43 (Chromosome 19 Open Reading Frame 43) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf43 Gene

Genomics for C19orf43 Gene

Regulatory Elements for C19orf43 Gene

Enhancers for C19orf43 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F012781 1.6 FANTOM5 ENCODE 44.4 -54.5 -54523 16.0 CREB3L1 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 ZNF136 CCDC130 ZNF564 ZNF442 ZNF844 ZNF44 WDR83OS ZNF799 TRMT1 ZNF625
GH19F012983 1 FANTOM5 Ensembl ENCODE 35.4 -250.0 -249968 3.5 HDGF PKNOX1 CREB3L1 ARNT MLX SIN3A ARID4B DMAP1 ZNF2 ZNF143 ZNF136 CCDC130 ZNF564 ZNF625 WDR83OS ZNF844 ZNF442 MRI1 ZNF799 ZNF44
GH19F012609 0.6 FANTOM5 ENCODE 26.1 +122.4 122415 4.8 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 ZNF136 ZNF564 WDR83OS ZNF700 C19orf43 ZNF799 ZNF44 HNRNPA1P10 ZNF791 JUNB
GH19F013491 1 ENCODE 20 -757.5 -757483 1.5 ZFP64 ZNF140 ZNF266 ZNF101 ZNF664 ZNF791 ZNF354C ZNF433 ZNF639 ZNF654 CCDC130 MRI1 ZNF564 WDR83OS RPS6P25 TRMT1 C19orf43 FBXW9 ZNF709 RFX1
GH19F013160 1.2 FANTOM5 ENCODE 18.7 -432.5 -432521 13.8 MLX ZFP64 FEZF1 DMAP1 YY1 ZNF143 ZNF263 SP3 NFYC TBX21 CCDC130 WDR83OS ZNF564 ZNF44 ZNF791 ZNF799 TRMT1 C19orf43 ZNF709 DCAF15
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C19orf43 on UCSC Golden Path with GeneCards custom track

Promoters for C19orf43 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001417961 375 2001 HDGF PKNOX1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF207

Genomic Location for C19orf43 Gene

Chromosome:
19
Start:
12,730,640 bp from pter
End:
12,734,775 bp from pter
Size:
4,136 bases
Orientation:
Minus strand

Genomic View for C19orf43 Gene

Genes around C19orf43 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf43 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf43 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf43 Gene

Proteins for C19orf43 Gene

  • Protein details for C19orf43 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BQ61-CS043_HUMAN
    Recommended name:
    Uncharacterized protein C19orf43
    Protein Accession:
    Q9BQ61

    Protein attributes for C19orf43 Gene

    Size:
    176 amino acids
    Molecular mass:
    18419 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C19orf43 Gene

Post-translational modifications for C19orf43 Gene

  • Ubiquitination at Lys 152
  • Modification sites at PhosphoSitePlus

Other Protein References for C19orf43 Gene

No data available for DME Specific Peptides for C19orf43 Gene

Domains & Families for C19orf43 Gene

Protein Domains for C19orf43 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C19orf43: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf43 Gene

Function for C19orf43 Gene

genes like me logo Genes that share phenotypes with C19orf43: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf43 Gene

Localization for C19orf43 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C19orf43 Gene COMPARTMENTS Subcellular localization image for C19orf43 gene
Compartment Confidence
nucleus 3
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf43 Gene

Pathways & Interactions for C19orf43 Gene

SuperPathways for C19orf43 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C19orf43 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C19orf43 Gene

Transcripts for C19orf43 Gene

Unigene Clusters for C19orf43 Gene

Chromosome 19 open reading frame 43:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf43 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b
SP1: -
SP2:

Relevant External Links for C19orf43 Gene

GeneLoc Exon Structure for
C19orf43
ECgene alternative splicing isoforms for
C19orf43

Expression for C19orf43 Gene

mRNA expression in normal human tissues for C19orf43 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C19orf43 Gene

This gene is overexpressed in Nasal epithelium (12.4), Peripheral blood mononuclear cells (11.0), Breast (9.1), and Tlymphocyte (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C19orf43 Gene



Protein tissue co-expression partners for C19orf43 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C19orf43 Gene:

C19orf43

SOURCE GeneReport for Unigene cluster for C19orf43 Gene:

Hs.515155
genes like me logo Genes that share expression patterns with C19orf43: view

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C19orf43 Gene

Orthologs for C19orf43 Gene

This gene was present in the common ancestor of animals.

Orthologs for C19orf43 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf43 34
  • 100 (n)
C19orf43 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C7H19orf43 34 35
  • 93.56 (n)
dog
(Canis familiaris)
Mammalia C20H19orf43 34
  • 93.18 (n)
C19orf43 35
  • 67 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2310036O22Rik 34 16 35
  • 92.05 (n)
rat
(Rattus norvegicus)
Mammalia RGD1564093 34
  • 91.28 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 71 (a)
OneToMany
-- 35
  • 70 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia C19orf43 35
  • 65 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.528 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.6514 34
zebrafish
(Danio rerio)
Actinopterygii LOC560758 34
  • 56.77 (n)
C3H19orf43 35
  • 46 (a)
OneToOne
Dr.15916 34
fruit fly
(Drosophila melanogaster)
Insecta CG18809 35
  • 18 (a)
OneToOne
Species where no ortholog for C19orf43 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C19orf43 Gene

ENSEMBL:
Gene Tree for C19orf43 (if available)
TreeFam:
Gene Tree for C19orf43 (if available)

Paralogs for C19orf43 Gene

No data available for Paralogs for C19orf43 Gene

Variants for C19orf43 Gene

Sequence variations from dbSNP and Humsavar for C19orf43 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10420261 -- 12,731,584(+) GCACA(C/T)GCGAC intron-variant
rs10420318 -- 12,731,675(+) ACTTT(C/T)CACGC intron-variant
rs1052589 -- 12,730,671(-) CACTT(C/T)TGGGA nc-transcript-variant, utr-variant-3-prime
rs111539387 -- 12,735,311(+) TGCTG(-/TTTTGGT)TTTTG upstream-variant-2KB
rs115008277 -- 12,735,359(+) CACTC(C/T)GTCTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C19orf43 Gene

Variant ID Type Subtype PubMed ID
dgv138n111 CNV deletion 26073780
nsv1160586 CNV duplication 26073780
nsv953977 CNV deletion 24416366

Variation tolerance for C19orf43 Gene

Gene Damage Index Score: 0.11; 2.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C19orf43 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C19orf43

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf43 Gene

Disorders for C19orf43 Gene

Relevant External Links for C19orf43

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C19orf43

No disorders were found for C19orf43 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf43 Gene

Publications for C19orf43 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  3. FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1. (PMID: 26752685) Scholz C.C. … Taylor C.T. (PLoS Biol. 2016) 3 64
  4. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3 64
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64

Products for C19orf43 Gene

Sources for C19orf43 Gene

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