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Aliases for C19orf26 Gene

Aliases for C19orf26 Gene

  • Chromosome 19 Open Reading Frame 26 2 3
  • DOS 3 4
  • Downstream Of STK11 2
  • Downstream Of Stk11 3
  • Protein Dos 3

External Ids for C19orf26 Gene

Summaries for C19orf26 Gene

GeneCards Summary for C19orf26 Gene

C19orf26 (Chromosome 19 Open Reading Frame 26) is a Protein Coding gene. Diseases associated with C19orf26 include morgagni cataract.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf26 Gene

Genomics for C19orf26 Gene

Genomic Location for C19orf26 Gene

Start:
1,228,060 bp from pter
End:
1,238,027 bp from pter
Size:
9,968 bases
Orientation:
Minus strand

Genomic View for C19orf26 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C19orf26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf26 Gene

Regulatory Elements for C19orf26 Gene

Proteins for C19orf26 Gene

  • Protein details for C19orf26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N350-DOS_HUMAN
    Recommended name:
    Protein Dos
    Protein Accession:
    Q8N350
    Secondary Accessions:
    • O43385

    Protein attributes for C19orf26 Gene

    Size:
    725 amino acids
    Molecular mass:
    75822 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C19orf26 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C19orf26 Gene

Proteomics data for C19orf26 Gene at MOPED

Post-translational modifications for C19orf26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C19orf26 Gene

No data available for DME Specific Peptides for C19orf26 Gene

Domains for C19orf26 Gene

Protein Domains for C19orf26 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C19orf26: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf26 Gene

Function for C19orf26 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C19orf26 Gene

Localization for C19orf26 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C19orf26 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C19orf26 Gene COMPARTMENTS Subcellular localization image for C19orf26 gene
Compartment Confidence
nucleus 2
cytoskeleton 1
cytosol 1
golgi apparatus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for C19orf26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C19orf26: view

Pathways for C19orf26 Gene

SuperPathways for C19orf26 Gene

No Data Available

Interacting Proteins for C19orf26 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000215376%0d%0a9606.ENSP00000265094%0d%0a
Selected Interacting proteins: ENSP00000215376 for C19orf26 Gene via STRING

Symbol External ID(s) Details
FBXW11

Gene Ontology (GO) - Biological Process for C19orf26 Gene

None

No data available for Pathways by source for C19orf26 Gene

Transcripts for C19orf26 Gene

mRNA/cDNA for C19orf26 Gene

Unigene Clusters for C19orf26 Gene

Chromosome 19 open reading frame 26:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf26 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c ^ 9
SP1: -
SP2:
SP3: -
SP4: - -

Relevant External Links for C19orf26 Gene

GeneLoc Exon Structure for
C19orf26
ECgene alternative splicing isoforms for
C19orf26

Expression for C19orf26 Gene

mRNA expression in normal human tissues for C19orf26 Gene

mRNA differential expression in normal tissues according to GTEx for C19orf26 Gene

This gene is overexpressed in Pituitary (6.6), Brain - Nucleus accumbens (basal ganglia) (4.8), and Brain - Cortex (4.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C19orf26 Gene

SOURCE GeneReport for Unigene cluster for C19orf26 Gene Hs.346575

genes like me logo Genes that share expressions with C19orf26: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C19orf26 Gene

Orthologs for C19orf26 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C19orf26 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf26 35
  • 98.07 (n)
  • 97.87 (a)
C19orf26 36
  • 85 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C19orf26 36
  • 43 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C19orf26 36
  • 39 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Dos 36
  • 47 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C19orf26 36
  • 37 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C19orf26 36
  • 42 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C19orf26 36
  • 40 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii C22H19orf26 (1 of 2) 36
  • 29 (a)
OneToMany
C22H19orf26 (2 of 2) 36
  • 10 (a)
OneToMany
Species with no ortholog for C19orf26:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C19orf26 Gene

ENSEMBL:
Gene Tree for C19orf26 (if available)
TreeFam:
Gene Tree for C19orf26 (if available)

Paralogs for C19orf26 Gene

Selected SIMAP similar genes for C19orf26 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with C19orf26: view

No data available for Paralogs for C19orf26 Gene

Variants for C19orf26 Gene

Sequence variations from dbSNP and Humsavar for C19orf26 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs2301758 -- 1,238,677(+) CACCC(C/G)AACCC upstream-variant-2KB
rs2301759 -- 1,238,900(+) TGGCT(C/T)CCAGC upstream-variant-2KB
rs2890122 -- 1,233,707(-) ACCTA(C/G)GGCCA intron-variant, reference, missense
rs3213645 -- 1,235,488(+) GGCTG(A/G)CCAGC intron-variant
rs3746102 -- 1,233,598(+) GCCCC(A/G)GGCCC reference, synonymous-codon, downstream-variant-500B, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for C19orf26 Gene

Variant ID Type Subtype PubMed ID
nsv910292 CNV Loss 21882294
dgv3555n71 CNV Loss 21882294
nsv9662 CNV Gain 18304495
dgv1055e1 CNV Complex 17122850
dgv3575n71 CNV Loss 21882294
dgv3580n71 CNV Loss 21882294
nsv470103 CNV Gain 18288195
nsv910420 CNV Loss 21882294
dgv3583n71 CNV Loss 21882294
dgv3585n71 CNV Loss 21882294
dgv3586n71 CNV Loss 21882294
nsv470104 CNV Loss 18288195
dgv3587n71 CNV Loss 21882294
nsv910442 CNV Gain+Loss 21882294
dgv3588n71 CNV Loss 21882294
dgv3589n71 CNV Loss 21882294
dgv3590n71 CNV Loss 21882294
dgv3591n71 CNV Loss 21882294
dgv3592n71 CNV Loss 21882294
dgv3593n71 CNV Loss 21882294
nsv828368 CNV Gain 20364138
nsv910466 CNV Loss 21882294

Relevant External Links for C19orf26 Gene

HapMap Linkage Disequilibrium report
C19orf26

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf26 Gene

Disorders for C19orf26 Gene

(1) MalaCards Diseases for C19orf26 Gene

Search for C19orf26 Gene in MalaCards »

(1) University of Copenhagen DISEASES for C19orf26 Gene

genes like me logo Genes that share disorders with C19orf26: view

No data available for UniProtKB/Swiss-Prot for C19orf26 Gene

Publications for C19orf26 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for C19orf26 Gene

  • antibodies-online peptides for C19orf26
  • antibodies-online antibodies for C19orf26
  • antibodies-online kits for C19orf26

Sources for C19orf26 Gene

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