C19orf24 Gene
protein-coding GIFtS: 36
GCID: GC19P001282
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chromosome 19 open reading frame 24
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Aliases
for C19orf24 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 19 Open Reading Frame 241 2 | | FLJ206401 | | Uncharacterized Membrane Protein C19orf242 |
Export aliases for C19orf24 gene to outside databasesPrevious GC identifers: GC19P001228 GC19P001229 GC19P001049 GC19P001276 GC19P001278 |
Summaries
for C19orf24 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C19orf24 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011255.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C19orf24 gene promoter:
GR p53 AP-1 NF-kappaB Sox9 Chx10 GR-alpha NF-kappaB1 Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for C19orf24
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C19orf24 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3C19orf24 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P001282: view genomic region
(about GC identifiers)
Start:
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1,275,026 bp from pter |
End:
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1,279,243 bp from pter |
Size:
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4,218 bases |
Orientation:
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plus strand |
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Proteins
for C19orf24 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CS024_HUMAN, Q9BVV8 (See
protein sequence)Recommended Name: Uncharacterized membrane protein C19orf24 precursor Size: 132 amino acids; 14249 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Sequence caution: Sequence=BAA91305.1; Type=Miscellaneous discrepancy;
Secondary accessions: Q9NWS2Explore the universe of human proteins at neXtProt for C19orf24: NX_Q9BVV8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BVV8
C19orf24 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060384.3
ENSEMBL proteins: ENSP00000386557
Human Recombinant Protein Products for C19orf24:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
C19orf24 for ontologies About GeneDecksing
C19orf24 Antibody Products:
Assay Products for C19orf24: |
Protein
Domains /
Families
for C19orf24 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
C19orf24 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9BVV8ProtoNet protein and cluster: Q9BVV8 |
Function
for C19orf24 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
2 GenomeRNAi human phenotypes for C19orf24:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf24 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf24
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C19orf24 (NM_017914) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C19orf24 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C19orf24 |
|
Pathways & Interactions
for C19orf24 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C19orf24
|
Drugs & Compounds
for C19orf24 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C19orf24
Search CenterWatch for drugs/clinical trials and news about C19orf24 / CS024
|
Transcripts
for C19orf24 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C19orf24 gene: NM_017914.3 Unigene Cluster for C19orf24: Chromosome 19 open reading frame 24 Hs.591383 [show with all ESTs]Unigene Representative Sequence: BC0120805 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000409293(uc002lrw.4) ENST00000469144(uc002lrx.4) ENST00000590269
ENST00000485191 ENST00000585716
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf24 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf24
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C19orf24 (NM_017914) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C19orf24 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C19orf24 |
Additional cDNA sequence: AK000647.1 AK096105.1 AK225502.1 BC000890.1 BC012080.1 8 DOTS entries: DT.91757535 DT.100008313 DT.91754765 DT.100025474 DT.75101483 DT.97787220 DT.100025472 DT.95296445 24/362 AceView cDNA sequences (see all 362): BM044526 BM893832 BE781053 BC012080 AI470071 BE782627 BX105110 BM691899 AI208430 CR607576 BI761802 BE207068 CR610772 BQ441878 AA232686 AI792654 BM703621 BU541426 BG163845 BU543140 BU845441 BQ957785 BM694499 NM_138422
GeneLoc Exon Structure
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Expression
for C19orf24 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C19orf24 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTCTGCAAA
About this image
See C19orf24 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C19orf24
SOURCE GeneReport for Unigene cluster: Hs.591383
SABiosciences Custom PCR Arrays for C19orf24
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C19orf24
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C19orf24 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C19orf24 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C19orf24 |
Orthologs
for C19orf24 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C19orf24 gene from 1/4 species (see all 4) About this table
ENSEMBL Gene Tree for C19orf24 (if available)
TreeFam Gene Tree for C19orf24 (if available) |
Paralogs
for C19orf24 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C19orf24 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for C19orf24 (1275026 - 1279243 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for C19orf24
5 CNVs: 30057 30058 4066 29684 30885 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C19orf24 |
|
Disorders
/ Diseases
for C19orf24 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C19orf24 for disorders About GeneDecksing
1  disease for C19orf24: About MalaCardspeutz-jeghers syndrome
Export disorders for C19orf24 gene to outside databases
|
Publications
for C19orf24 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C19orf24 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C19orf24) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel recently evolved gene C19orf24 encodes a non-classical secreted protein. (PubMed id 16847563)1, 3 Wang X.R....Han Z.G. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)2 Olsen J.V....Mann M. (2006)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
- Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)
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External Searches for C19orf24 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C19orf24 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C19orf24 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C19orf24 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C19orf24 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C19orf24 gene:
Search GeneIP for patents involving C19orf24
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C19orf24 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C19orf24 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C19orf24 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C19orf24 | | | OriGene Protein Over-expression Lysate for C19orf24 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C19orf24 | | OriGene 3'-UTR Clone for C19orf24 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf24 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf24 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for C19orf24 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C19orf24 | | OriGene Custom Protein Services for C19orf24 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C19orf24 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C19orf24 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C19orf24 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C19orf24 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C19orf24 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C19orf24 |
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 | | | C19orf24 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  |  | | | | Search ThermoFisher Antibodies for C19orf24 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C19orf24 |
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