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Aliases for C19orf24 Gene

Aliases for C19orf24 Gene

  • Chromosome 19 Open Reading Frame 24 2 3 5

External Ids for C19orf24 Gene

Previous GeneCards Identifiers for C19orf24 Gene

  • GC19P001228
  • GC19P001229
  • GC19P001049
  • GC19P001276
  • GC19P001278
  • GC19P001282
  • GC19P001289
  • GC19P001292
  • GC19P001294
  • GC19P001302
  • GC19P001304
  • GC19P001309
  • GC19P001311

Summaries for C19orf24 Gene

GeneCards Summary for C19orf24 Gene

C19orf24 (Chromosome 19 Open Reading Frame 24) is a Protein Coding gene.

Additional gene information for C19orf24 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf24 Gene

Genomics for C19orf24 Gene

Regulatory Elements for C19orf24 Gene

Enhancers for C19orf24 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H001236 1.9 FANTOM5 ENCODE dbSUPER 45.9 -18.6 -18580 41 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 SP3 NFYC ZC3H11A SF3A2 TCF3 LOC100288123 MIER2 CIRBP TMEM259 DAZAP1 PTBP1 C19orf24 MUM1
GH19H001382 1.5 ENCODE dbSUPER 21.1 +108.6 108588 2 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC ZC3H11A ZFP41 SF3A2 CIRBP TMEM259 DAZAP1 MUM1 TCF3 LOC100288123 GRIN3B PTBP1 SPPL2B
GH19H001437 1.4 ENCODE dbSUPER 21.1 +164.0 164046 4 MLX DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC ZFP41 SSRP1 ZNF610 SF3A2 TCF3 TMEM259 LOC100288123 PTBP1 DAZAP1 MED16 GRIN3B ENSG00000267317 MUM1
GH19H001745 1.9 FANTOM5 Ensembl ENCODE dbSUPER 12.9 +473.0 473013 5 HDGF PKNOX1 ARNT ZNF2 YY1 ZNF766 CBX5 FOS SP3 JUNB CIRBP SPPL2B AP3D1 SCAMP4 MUM1 LINC01775 SLC39A3 C19orf24 ATP8B3 REXO1
GH19H001442 1.6 FANTOM5 ENCODE dbSUPER 13 +168.9 168864 3 HDGF PKNOX1 ARNT SIN3A FEZF1 DMAP1 ZNF2 ZNF143 ZNF207 FOS APC2 SF3A2 RNA5SP462 C19orf24 DAZAP1 C19orf25 PCSK4 REEP6 CIRBP GRIN3B
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C19orf24 on UCSC Golden Path with GeneCards custom track

Promoters for C19orf24 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000105655 362 1201 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF207 ZNF143 FOS

Genomic Location for C19orf24 Gene

Chromosome:
19
Start:
1,275,438 bp from pter
End:
1,279,249 bp from pter
Size:
3,812 bases
Orientation:
Plus strand

Genomic View for C19orf24 Gene

Genes around C19orf24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf24 Gene

Proteins for C19orf24 Gene

  • Protein details for C19orf24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BVV8-CS024_HUMAN
    Recommended name:
    Uncharacterized membrane protein C19orf24
    Protein Accession:
    Q9BVV8
    Secondary Accessions:
    • Q9NWS2

    Protein attributes for C19orf24 Gene

    Size:
    132 amino acids
    Molecular mass:
    14249 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA91305.1; Type=Miscellaneous discrepancy; Evidence={ECO:0000305};

neXtProt entry for C19orf24 Gene

Post-translational modifications for C19orf24 Gene

  • Glycosylation at posLast=4747
  • Modification sites at PhosphoSitePlus

Other Protein References for C19orf24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C19orf24 Gene

Domains & Families for C19orf24 Gene

Gene Families for C19orf24 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for C19orf24 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C19orf24 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C19orf24: view

No data available for UniProtKB/Swiss-Prot for C19orf24 Gene

Function for C19orf24 Gene

Phenotypes From GWAS Catalog for C19orf24 Gene

genes like me logo Genes that share phenotypes with C19orf24: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C19orf24
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf24 Gene

Localization for C19orf24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C19orf24 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C19orf24 gene
Compartment Confidence
extracellular 5
nucleus 3
golgi apparatus 3
cytosol 2
plasma membrane 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (2)
  • Nuclear speckles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for C19orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IDA 16847563
GO:0005737 cytoplasm IDA 16847563
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C19orf24: view

Pathways & Interactions for C19orf24 Gene

SuperPathways for C19orf24 Gene

No Data Available

Interacting Proteins for C19orf24 Gene

Gene Ontology (GO) - Biological Process for C19orf24 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C19orf24 Gene

Drugs & Compounds for C19orf24 Gene

No Compound Related Data Available

Transcripts for C19orf24 Gene

Unigene Clusters for C19orf24 Gene

Chromosome 19 open reading frame 24:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C19orf24
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf24 Gene

No ASD Table

Relevant External Links for C19orf24 Gene

GeneLoc Exon Structure for
C19orf24
ECgene alternative splicing isoforms for
C19orf24

Expression for C19orf24 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C19orf24 Gene

NURSA nuclear receptor signaling pathways regulating expression of C19orf24 Gene:

C19orf24

SOURCE GeneReport for Unigene cluster for C19orf24 Gene:

Hs.591383
genes like me logo Genes that share expression patterns with C19orf24: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf24 Gene

Orthologs for C19orf24 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C19orf24 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C19orf24 34
  • 98 (a)
OneToOne
C19H19orf24 33
  • 95.2 (n)
dog
(Canis familiaris)
Mammalia C19orf24 34
  • 88 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C7H19orf24 33 34
  • 81.13 (n)
mouse
(Mus musculus)
Mammalia 1600002K03Rik 33 16 34
  • 69.18 (n)
rat
(Rattus norvegicus)
Mammalia RGD1562114 33
  • 66.67 (n)
Species where no ortholog for C19orf24 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C19orf24 Gene

ENSEMBL:
Gene Tree for C19orf24 (if available)
TreeFam:
Gene Tree for C19orf24 (if available)

Paralogs for C19orf24 Gene

No data available for Paralogs for C19orf24 Gene

Variants for C19orf24 Gene

Sequence variations from dbSNP and Humsavar for C19orf24 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000091381 -- 1,277,843(+) GATCT(C/G)TGCTC intron-variant
rs1000099801 -- 1,275,516(+) CGCAT(-/A)GGGGC upstream-variant-2KB
rs1000401424 -- 1,275,592(+) TCCTG(C/T)TGGCG reference, synonymous-codon
rs1000465668 -- 1,279,332(+) CATCT(G/T)CGACC downstream-variant-500B
rs1000754597 -- 1,279,525(+) GATCC(C/T)CACAT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for C19orf24 Gene

Variant ID Type Subtype PubMed ID
dgv136n111 CNV deletion 26073780
esv1779341 CNV insertion 17803354
esv2758743 CNV gain+loss 17122850
esv3368458 CNV duplication 20981092
esv3395739 CNV insertion 20981092
esv3643389 CNV gain 21293372
esv3643390 CNV loss 21293372
esv3643391 CNV gain 21293372
esv990677 CNV insertion 20482838
nsv1055164 CNV gain 25217958
nsv1058677 CNV loss 25217958
nsv1060536 CNV gain 25217958
nsv1143898 CNV deletion 24896259
nsv1160555 CNV deletion 26073780
nsv138017 CNV insertion 16902084
nsv470103 CNV gain 18288195
nsv470104 CNV loss 18288195
nsv953941 CNV deletion 24416366
nsv9662 CNV gain 18304495

Variation tolerance for C19orf24 Gene

Gene Damage Index Score: 0.57; 12.22% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C19orf24 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C19orf24

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf24 Gene

Disorders for C19orf24 Gene

Relevant External Links for C19orf24

Genetic Association Database (GAD)
C19orf24
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C19orf24

No disorders were found for C19orf24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf24 Gene

Publications for C19orf24 Gene

  1. A novel recently evolved gene C19orf24 encodes a non-classical secreted protein. (PMID: 16847563) Wang XR … Han ZG (Cellular & molecular biology letters 2006) 2 3 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  4. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PMID: 20068231) Olsen JV … Mann M (Science signaling 2010) 4 60
  5. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N … Gygi SP (Proceedings of the National Academy of Sciences of the United States of America 2008) 4 60

Products for C19orf24 Gene

Sources for C19orf24 Gene

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