C18orf56 Gene
protein-coding GIFtS: 37
GCID: GC18M000640
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chromosome 18 open reading frame 56
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Aliases
for C18orf56 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 18 Open Reading Frame 561 2 | | Putative Uncharacterized Protein C18orf562 |
Export aliases for C18orf56 gene to outside databasesPrevious GC identifer: GC18U900223 |
Summaries
for C18orf56 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C18orf56 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000018.9 NC_018929.1 NT_010859.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C18orf56 gene promoter:
AML1a p53 Egr-1 RREB-1 Ik-2 POU2F1 POU2F1a aMEF-2 MRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for C18orf56
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C18orf56 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 18p11.32 Ensembl cytogenetic band: 18p11.32 HGNC cytogenetic band: 18p11.32C18orf56 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 18 GeneLoc Exon Structure GeneLoc location for GC18M000640: view genomic region
(about GC identifiers)
Start:
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641,320 bp from pter |
End:
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658,340 bp from pter |
Size:
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17,021 bases |
Orientation:
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minus strand |
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Proteins
for C18orf56 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CR056_HUMAN, Q8TAI1 (See
protein sequence)Recommended Name: Putative uncharacterized protein C18orf56 Size: 123 amino acids; 13402 Da
Secondary accessions: A8K1S1Explore the universe of human proteins at neXtProt for C18orf56: NX_Q8TAI1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TAI1
C18orf56 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001012734.2
ENSEMBL proteins: ENSP00000463397 ENSP00000316465
Human Recombinant Protein Products:
C18orf56 Antibody Products:
Assay Products for C18orf56: |
Protein
Domains /
Families
for C18orf56 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8TAI1 |
Function
for C18orf56 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C18orf56
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C18orf56 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C18orf56 (NM_001012716) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C18orf56 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C18orf56 |
|
Pathways & Interactions
for C18orf56 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C18orf56
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
3 Interacting proteins for C18orf56 (Q8TAI12, 3 ENSP000003164654) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C18orf56 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
C18orf56 for compounds About GeneDecksing
 Browse Tocris compounds for C18orf56
7 PharmGKB related drug/compound annotations for C18orf56 geneAbout this table
Search CenterWatch for drugs/clinical trials and news about C18orf56 / CR056
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Transcripts
for C18orf56 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C18orf56 gene: NM_001012716.2 Unigene Cluster for C18orf56: Chromosome 18 open reading frame 56 Hs.274959 [show with all ESTs]Unigene Representative Sequence: BI7544012 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000585033 ENST00000323813(uc002kkr.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C18orf56
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C18orf56 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C18orf56 (NM_001012716) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C18orf56 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C18orf56 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C18orf56
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C18orf56 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C18orf56 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C18orf56 |
Additional cDNA sequence: AK289986.1 BC028301.1 4 DOTS entries: DT.209162 DT.121095554 DT.111185 DT.100743389
GeneLoc Exon Structure
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Expression
for C18orf56 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C18orf56 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATATTCTTA
About this image
See C18orf56 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C18orf56
SOURCE GeneReport for Unigene cluster: Hs.274959
SABiosciences Custom PCR Arrays for C18orf56
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C18orf56
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C18orf56 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C18orf56 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C18orf56 |
Orthologs
for C18orf56 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for C18orf56 (if available)
TreeFam Gene Tree for C18orf56 (if available) |
Paralogs
for C18orf56 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C18orf56 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 18 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C18orf56 (641320 - 658340 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for C18orf56
2 CNVs: 5044 67286 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C18orf56 |
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Disorders
/ Diseases
for C18orf56 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 C18orf56 for disorders About MalaCards
C18orf56 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: C18orf56 (4 documents)
Export disorders for C18orf56 gene to outside databases
|
Publications
for C18orf56 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C18orf56 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C18orf56) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- Protein microarray analysis identifies human cellular prion protein interactors. (PubMed id 18482256)1 Satoh J....Tabunoki H. (2009)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- DNA sequence and analysis of human chromosome 18. (PubMed id 16177791)2 Nusbaum C.... Lander E.S. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
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External Searches for C18orf56 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C18orf56 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C18orf56 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C18orf56 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C18orf56 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C18orf56 gene:
Search GeneIP for patents involving C18orf56
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C18orf56 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C18orf56 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C18orf56 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C18orf56 | | | OriGene Protein Over-expression Lysate for C18orf56 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C18orf56 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C18orf56 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C18orf56 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for C18orf56 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C18orf56 | | OriGene Custom Protein Services for C18orf56 | | | OriGene Custom Immunoassay Development | | |
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 | | | C18orf56 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for C18orf56 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C18orf56 |
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