Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C18orf54 Gene

protein-coding   GIFtS: 48
GCID: GC18P051884

Chromosome 18 Open Reading Frame 54

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Chromosome 18 Open Reading Frame 541 2     Hypothetical Protein V32
Lung Adenoma Susceptibility Protein 21 2     Hypothetical Protein V42
LAS22 5     Hypothetical Protein V52
Hypothetical Protein V12     

External Ids:    HGNC: 137961   Entrez Gene: 1626812   Ensembl: ENSG000001668457   OMIM: 6132585   UniProtKB: Q8IYD93   

Export aliases for C18orf54 gene to outside databases

Previous GC identifers: GC18P050140 GC18P048741


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for C18orf54 Gene: 
C18orf54 (chromosome 18 open reading frame 54) is a protein-coding gene. Diseases associated with C18orf54 include inferior myocardial infarction, and lung adenoma.

UniProtKB/Swiss-Prot: LAS2_HUMAN, Q8IYD9
Function: Might play a role in cell proliferation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NT_010966.14  NC_018929.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the C18orf54 gene promoter:
         TBP   AML1a   SRF (504 AA)   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   CUTL1   STAT5A   POU3F2   GATA-1   RORalpha2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for C18orf54

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C18orf54


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q21.2   Ensembl cytogenetic band:  18q21.2   HGNC cytogenetic band: 18q21

C18orf54 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C18orf54 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P051884:  view genomic region     (about GC identifiers)

Start:
51,884,287 bp from pter      End:
51,911,588 bp from pter
Size:
27,302 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: LAS2_HUMAN, Q8IYD9 (See protein sequence)
Recommended Name: Lung adenoma susceptibility protein 2 precursor  
Size: 372 amino acids; 41811 Da
Subcellular location: Secreted (Potential)
Sequence caution: Sequence=BAC86570.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q6MZU3 Q6ZTL6
Alternative splicing: 2 isoforms:  Q8IYD9-1   Q8IYD9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for C18orf54: NX_Q8IYD9

Explore proteomics data for C18orf54 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IYD9

  • C18orf54 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    C18orf54 Protein Expression
    REFSEQ proteins: NP_775800.3  
    ENSEMBL proteins: 
     ENSP00000462317   ENSP00000372368   ENSP00000300091   ENSP00000462201  

    Human Recombinant Protein Products for C18orf54: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for C18orf54
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for C18orf54
    GenScript Custom Purified and Recombinant Proteins Services for C18orf54
    Novus Biologicals C18orf54 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for C18orf54 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    C18orf54 for ontologies           About GeneDecksing



    C18orf54 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for C18orf54
    GenScript Custom Superior Antibodies Services for C18orf54
    Novus Biologicals C18orf54 Antibodies
    Abcam antibodies for C18orf54
    Cloud-Clone Corp. Antibodies for C18orf54 
    ThermoFisher Antibodies for C18orf54
    LSBio Antibodies in human, mouse, rat for C18orf54 

    Assay Products for C18orf54: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for C18orf54
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for C18orf54
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for C18orf54 
    Cloud-Clone Corp. CLIAs for C18orf54


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q8IYD9


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LAS2_HUMAN, Q8IYD9
    Function: Might play a role in cell proliferation (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for C18orf54:

     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for C18orf54 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for C18orf54

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for C18orf54 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for C18orf54 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C18orf54
    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate C18orf54 (see all 20):
    hsa-miR-7-1* hsa-miR-29a* hsa-miR-3662 hsa-miR-23a hsa-miR-103a-2* hsa-miR-7-2* hsa-miR-513a-3p hsa-miR-130a*
    SwitchGear 3'UTR luciferase reporter plasmidC18orf54 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for C18orf54
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C18orf54

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for C18orf54
    Sirion Biotech Customized adenovirus for overexpression of C18orf54

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for C18orf54 (see all 8)
    OriGene ORF clones in mouse, rat for C18orf54
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: C18orf54 (NM_173529)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for C18orf54
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C18orf54
    Sirion Biotech Customized lentivirus for stable overexpression of C18orf54 
                         Customized lentivirus expression plasmids for stable overexpression of C18orf54 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for C18orf54
    Search LifeMap BioReagents cell lines for C18orf54
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C18orf54


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C18orf54

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for C18orf54 (Q8IYD92, 3 ENSP000003000914) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PARP2Q9UGN52, 3, ENSP000002504164MINT-8201924 I2D: score=1 STRING: ENSP00000250416
    MAGEA11P433642, 3, ENSP000003473584MINT-67622 I2D: score=4 STRING: ENSP00000347358
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for C18orf54 (LAS2)

    Search CenterWatch for drugs/clinical trials and news about C18orf54 / LAS2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for C18orf54 gene: 
    NM_173529.4  

    Unigene Cluster for C18orf54:

    Chromosome 18 open reading frame 54
    Hs.208701  [show with all ESTs]
    Unigene Representative Sequence: AB267906
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000578138 ENST00000382911 ENST00000300091(uc002lfn.4 uc002lfo.4)
    ENST00000582188 ENST00000579594
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C18orf54
    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate C18orf54 (see all 20):
    hsa-miR-7-1* hsa-miR-29a* hsa-miR-3662 hsa-miR-23a hsa-miR-103a-2* hsa-miR-7-2* hsa-miR-513a-3p hsa-miR-130a*
    SwitchGear 3'UTR luciferase reporter plasmidC18orf54 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for C18orf54
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C18orf54
    Clone
    Products:
         
    OriGene clones in human, mouse for C18orf54 (see all 8)
    OriGene ORF clones in mouse, rat for C18orf54
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: C18orf54 (NM_173529)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for C18orf54
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C18orf54
    Sirion Biotech Customized lentivirus for stable overexpression of C18orf54 
                         Customized lentivirus expression plasmids for stable overexpression of C18orf54 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for C18orf54
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C18orf54
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C18orf54
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C18orf54

    Additional mRNA sequence: 

    AB267906.1 AB330143.1 AB330144.1 AB353076.1 AB353077.1 AK126503.1 BC036054.2 BC043651.2 
    BX640877.1 

    4 DOTS entries:

    DT.112011  DT.92029918  DT.91739043  DT.100017463 

    24/61 AceView cDNA sequences (see all 61):

    AA741180 BM979842 BX090828 AA281260 BX088973 AK126503 AA831040 AA831399 
    BF513703 AA629335 BX640877 BX334458 BX642966 AA626254 AI753538 AA587685 
    AA812838 BX344497 AW182245 AI217222 AL704560 NM_173529 AI809253 AA281309 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for C18orf54    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b
    SP1:                                                      
    SP2:        -     -                                       


    ECgene alternative splicing isoforms for C18orf54

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    C18orf54 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAAAATATT
    C18orf54 Expression
    About this image


    See C18orf54 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for C18orf54

    SOURCE GeneReport for Unigene cluster: Hs.208701
        SABiosciences Custom PCR Arrays for C18orf54
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for C18orf54
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C18orf54
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C18orf54
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C18orf54
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C18orf54

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for C18orf54 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia 4930503L19Rik5 RIKEN cDNA 4930503L19 gene   --   18 (44.42 cM) 70453140 
    lizard
    (Anolis carolinensis)
    Reptilia C18ORF546
    Uncharacterized protein
    29(a)
    1 ↔ 1
    GL343213.1(148307-158159)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.348732 Xenopus laevis transcribed sequence 73.15(n)    BX847761.1 
    zebrafish
    (Danio rerio)
    Actinopterygii C21H18orf546
    chromosome 18 open reading frame 54
    24(a)
    1 ↔ 1
    21(1952470-1967162)


    ENSEMBL Gene Tree for C18orf54 (if available)
    TreeFam Gene Tree for C18orf54 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for C18orf54 gene
    4 SIMAP similar genes for C18orf54 using alignment to 2 protein entries:     J3KRX3_HUMAN (see all proteins):
    B9838V1    B9838V3    B9838V5    LAS2

    C18orf54 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/571 SNPs in C18orf54 are shown (see all 571)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs741804681,2
    C--48763952(+) CTGAA-/TCATCATA 1 -- int12Minor allele frequency- TCA:0.25NA CSA 4
    rs1831579191,2
    --51883284(+) CACAAC/TAGACC 1 -- us2k10--------
    rs16579021,2
    C,F,H--51883313(+) TGAACG/ATTATA 1 -- us2k17Minor allele frequency- A:0.07MN NS EA WA NA 838
    rs1403606541,2
    --51883734(+) TCCCAC/TCCCTG 1 -- us2k10--------
    rs1456749501,2
    --51883746(+) CTAAAC/TTCGGG 1 -- us2k10--------
    rs1134939191,2
    C,F--51883775(+) CTTTGA/TGTGTG 1 -- us2k11Minor allele frequency- T:0.00CSA 1
    rs734768171,2
    C--51883865(+) ACGATA/GTCTTA 1 -- us2k12Minor allele frequency- G:0.06WA 120
    rs1875810971,2
    --51883911(+) GAACTC/GACTTG 1 -- us2k10--------
    rs1427212161,2
    --51884092(+) GGCGTA/GGGGGG 1 -- us2k10--------
    rs1916906101,2
    --51884108(+) ACTTGA/GATGCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for C18orf54 (51884287 - 51911588 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for C18orf54:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv909656CNV Loss21882294
    nsv828245CNV Gain20364138

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing C18orf54
    DNA2.0 Custom Variant and Variant Library Synthesis for C18orf54

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613258    OMIM disorders: --

    4 diseases for C18orf54:    About MalaCards
    inferior myocardial infarction    lung adenoma    adenoma    myocardial infarction

    2 diseases from the University of Copenhagen DISEASES database for C18orf54:
    Inferior myocardial infarction     Lung adenoma

    C18orf54 for disorders           About GeneDecksing

    Genetic Association Database (GAD): C18orf54

    Export disorders for C18orf54 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for C18orf54 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with C18orf54)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (2013)
    4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    5. Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study. (PubMed id 17903297)4 Seshadri S....Wolf P.A. (2007)
    6. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (2007)
    7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    9. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 162681 HGNC: 13796 AceView: MGC33382 Ensembl:ENSG00000166845 euGenes: HUgn162681
    ECgene: C18orf54 H-InvDB: C18orf54

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for C18orf54 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for C18orf54 gene:
    Search GeneIP for patents involving C18orf54

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for C18orf54  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for C18orf54  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for C18orf54  
     OriGene qSTAR qPCR primer pairs in human, mouse for C18orf54   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for C18orf54   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for C18orf54   OriGene Custom Protein Services for C18orf54  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C18orf54
     QIAGEN SeqTarget long-range PCR primers for resequencing C18orf54
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C18orf54
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C18orf54
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C18orf54
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C18orf54
     GenScript Custom Purified and Recombinant Proteins Services for C18orf54 GenScript cDNA clones with any tag delivered in your preferred vector for C18orf54
     GenScript Custom Assay Services for C18orf54 GenScript Custom Superior Antibodies Services for C18orf54
     GenScript Custom overexpressing Cell Line Services for C18orf54 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in C18orf54 promoter
     Search Chromatin IP Primers for C18orf54
     RT2 qPCR Primer Assay in human, mouse / rat C18orf54
     Search GNC Networks for C18orf54
     SABiosciences Custom PCR Arrays for C18orf54
     Search Tocris compounds for C18orf54 (LAS2)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     C18orf54 antibodies
     C18orf54 lysates
     Antibodies for C18orf54
     See all of Abcam's Antibodies, Kits and Proteins for C18orf54
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for C18orf54
     Antibodies for C18orf54
     ELISAs for C18orf54
     CLIAs for C18orf54
     Search LifeMap BioReagents cell lines for C18orf54
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C18orf54
     SwitchGear 3'UTR luciferase reporter plasmids for C18orf54
     Browse SwitchGear Promoter luciferase reporter plasmids for C18orf54
     ThermoFisher Antibodies for C18orf54
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C18orf54
     inGenious Targeting Laboratory - Custom generated mouse model solutions for C18orf54
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for C18orf54
    Customized:
     lentivirus for stable overexpression of C18orf54
     lentivirus expression plasmids for stable overexpression of C18orf54
     adenovirus for overexpression of C18orf54
     LSBio Antibodies in human, mouse, rat for C18orf54
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      C18orf54 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4