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Aliases for C18orf32 Gene

Aliases for C18orf32 Gene

  • Chromosome 18 Open Reading Frame 32 2 3 5
  • Putative NF-Kappa-B-Activating Protein 200 4

External Ids for C18orf32 Gene

Previous GeneCards Identifiers for C18orf32 Gene

  • GC18M045264
  • GC18M047008
  • GC18M043861

Summaries for C18orf32 Gene

GeneCards Summary for C18orf32 Gene

C18orf32 (Chromosome 18 Open Reading Frame 32) is a Protein Coding gene. GO annotations related to this gene include signal transducer activity and structural constituent of ribosome.

UniProtKB/Swiss-Prot for C18orf32 Gene

  • May activate the NF-kappa-B signaling pathway.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C18orf32 Gene

Genomics for C18orf32 Gene

Regulatory Elements for C18orf32 Gene

Enhancers for C18orf32 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C18orf32 on UCSC Golden Path with GeneCards custom track

Promoters for C18orf32 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C18orf32 on UCSC Golden Path with GeneCards custom track

Genomic Location for C18orf32 Gene

49,477,250 bp from pter
49,487,274 bp from pter
10,025 bases
Minus strand

Genomic View for C18orf32 Gene

Genes around C18orf32 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C18orf32 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C18orf32 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C18orf32 Gene

Proteins for C18orf32 Gene

  • Protein details for C18orf32 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0729 protein C18orf32
    Protein Accession:

    Protein attributes for C18orf32 Gene

    76 amino acids
    Molecular mass:
    8669 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C18orf32 Gene

Proteomics data for C18orf32 Gene at MOPED

Post-translational modifications for C18orf32 Gene

  • Ubiquitination at Lys 39
  • Modification sites at PhosphoSitePlus

Other Protein References for C18orf32 Gene

Antibody Products

No data available for DME Specific Peptides for C18orf32 Gene

Domains & Families for C18orf32 Gene

Protein Domains for C18orf32 Gene


Suggested Antigen Peptide Sequences for C18orf32 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0729 family.
  • Belongs to the UPF0729 family.
genes like me logo Genes that share domains with C18orf32: view

No data available for Gene Families for C18orf32 Gene

Function for C18orf32 Gene

Molecular function for C18orf32 Gene

UniProtKB/Swiss-Prot Function:
May activate the NF-kappa-B signaling pathway.

Phenotypes for C18orf32 Gene

GenomeRNAi human phenotypes for C18orf32:
genes like me logo Genes that share phenotypes with C18orf32: view

Animal Model Products

CRISPR Products

miRNA for C18orf32 Gene

miRTarBase miRNAs that target C18orf32

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C18orf32 Gene

Localization for C18orf32 Gene

Subcellular locations from

Jensen Localization Image for C18orf32 Gene COMPARTMENTS Subcellular localization image for C18orf32 gene
Compartment Confidence
extracellular 3
nucleus 2
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C18orf32 Gene

Pathways & Interactions for C18orf32 Gene

SuperPathways for C18orf32 Gene

No Data Available

Interacting Proteins for C18orf32 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000323199 Q8TCD1-CR032_HUMAN for C18orf32 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for C18orf32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IMP 12761501
genes like me logo Genes that share ontologies with C18orf32: view

No data available for Pathways by source and SIGNOR curated interactions for C18orf32 Gene

Drugs & Compounds for C18orf32 Gene

No Compound Related Data Available

Transcripts for C18orf32 Gene

mRNA/cDNA for C18orf32 Gene

(2) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C18orf32 Gene

Chromosome 18 open reading frame 32:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C18orf32 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c
SP1: - - -
SP2: - -
SP3: -

Relevant External Links for C18orf32 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C18orf32 Gene

mRNA expression in normal human tissues for C18orf32 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C18orf32 Gene

This gene is overexpressed in Breast (35.3) and Peripheral blood mononuclear cells (17.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C18orf32 Gene

SOURCE GeneReport for Unigene cluster for C18orf32 Gene Hs.603040

genes like me logo Genes that share expression patterns with C18orf32: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C18orf32 Gene

Orthologs for C18orf32 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C18orf32 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C24H18orf32 35
  • 91.23 (n)
  • 84.21 (a)
C24H18orf32 36
  • 84 (a)
(Canis familiaris)
Mammalia C7H18orf32 35
  • 88.16 (n)
  • 80.26 (a)
C18orf32 36
  • 80 (a)
(Mus musculus)
Mammalia BC031181 35
  • 81.94 (n)
  • 80.56 (a)
BC031181 16
BC031181 36
  • 81 (a)
(Pan troglodytes)
Mammalia C18H18orf32 35
  • 97.81 (n)
  • 96.05 (a)
C18orf32 36
  • 96 (a)
(Rattus norvegicus)
Mammalia RGD1562987 35
  • 80.56 (n)
  • 76.39 (a)
(Monodelphis domestica)
Mammalia C18orf32 36
  • 61 (a)
(Ornithorhynchus anatinus)
Mammalia C18orf32 36
  • 22 (a)
(Gallus gallus)
Aves C18orf32 36
  • 58 (a)
(Anolis carolinensis)
Reptilia C18orf32 36
  • 48 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 44 (a)
Species with no ortholog for C18orf32:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C18orf32 Gene

Gene Tree for C18orf32 (if available)
Gene Tree for C18orf32 (if available)

Paralogs for C18orf32 Gene

genes like me logo Genes that share paralogs with C18orf32: view

No data available for Paralogs for C18orf32 Gene

Variants for C18orf32 Gene

Sequence variations from dbSNP and Humsavar for C18orf32 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
VAR_039374 -

Structural Variations from Database of Genomic Variants (DGV) for C18orf32 Gene

Variant ID Type Subtype PubMed ID
nsv2294 CNV Loss 18451855
nsv2295 CNV Insertion 18451855

Variation tolerance for C18orf32 Gene

Residual Variation Intolerance Score: 66.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.05; 1.21% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C18orf32 Gene

Disorders for C18orf32 Gene

Relevant External Links for C18orf32

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C18orf32 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C18orf32 Gene

Publications for C18orf32 Gene

  1. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PMID: 12761501) Matsuda A. … Sugano S. (Oncogene 2003) 3 4 67
  2. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. (PMID: 26638075) Gupta G.D. … Pelletier L. (Cell 2015) 3
  3. The identification of novel proteins that interact with the GLP-1 receptor and restrain its activity. (PMID: 23864651) Huang X. … Wheeler M.B. (Mol. Endocrinol. 2013) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for C18orf32 Gene

Sources for C18orf32 Gene