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Aliases for C18orf25 Gene

Aliases for C18orf25 Gene

  • Chromosome 18 Open Reading Frame 25 2 3
  • ARKadia-Like 1 2 3
  • Uncharacterized Protein C18orf25 3
  • RNF111L1 3
  • ARKL1 3

External Ids for C18orf25 Gene

Previous GeneCards Identifiers for C18orf25 Gene

  • GC18P042049
  • GC18P043753
  • GC18P040611

Summaries for C18orf25 Gene

GeneCards Summary for C18orf25 Gene

C18orf25 (Chromosome 18 Open Reading Frame 25) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C18orf25 Gene

Genomics for C18orf25 Gene

Regulatory Elements for C18orf25 Gene

Genomic Location for C18orf25 Gene

Start:
46,173,553 bp from pter
End:
46,266,992 bp from pter
Size:
93,440 bases
Orientation:
Plus strand

Genomic View for C18orf25 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C18orf25 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C18orf25 Gene

Proteins for C18orf25 Gene

  • Protein details for C18orf25 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96B23-CR025_HUMAN
    Recommended name:
    Uncharacterized protein C18orf25
    Protein Accession:
    Q96B23
    Secondary Accessions:
    • A8K123
    • A8KAB6
    • Q5XG78
    • Q6N058
    • Q86TB5
    • Q8TCQ5

    Protein attributes for C18orf25 Gene

    Size:
    403 amino acids
    Molecular mass:
    43324 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C18orf25 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C18orf25 Gene

Proteomics data for C18orf25 Gene at MOPED

Post-translational modifications for C18orf25 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C18orf25 Gene

No data available for DME Specific Peptides for C18orf25 Gene

Domains for C18orf25 Gene

Protein Domains for C18orf25 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C18orf25: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C18orf25 Gene

Function for C18orf25 Gene

miRNA for C18orf25 Gene

miRTarBase miRNAs that target C18orf25

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C18orf25 Gene

Localization for C18orf25 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C18orf25 Gene COMPARTMENTS Subcellular localization image for C18orf25 gene
Compartment Confidence
cytosol 2
nucleus 2
cytoskeleton 1
endoplasmic reticulum 1
extracellular 1
golgi apparatus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C18orf25 Gene

Pathways for C18orf25 Gene

SuperPathways for C18orf25 Gene

No Data Available

Interacting Proteins for C18orf25 Gene

Selected Interacting proteins: Q96B23-CR025_HUMAN for C18orf25 Gene via MINT I2D

Symbol External ID(s) Details
UBE2I
--
--

Gene Ontology (GO) - Biological Process for C18orf25 Gene

None

No data available for Pathways by source for C18orf25 Gene

Transcripts for C18orf25 Gene

Unigene Clusters for C18orf25 Gene

Chromosome 18 open reading frame 25:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C18orf25 Gene

No ASD Table

Relevant External Links for C18orf25 Gene

GeneLoc Exon Structure for
C18orf25
ECgene alternative splicing isoforms for
C18orf25

Expression for C18orf25 Gene

mRNA expression in normal human tissues for C18orf25 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for C18orf25 Gene

SOURCE GeneReport for Unigene cluster for C18orf25 Gene Hs.116486

genes like me logo Genes that share expressions with C18orf25: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C18orf25 Gene

Orthologs for C18orf25 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C18orf25 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C18H18orf25 35
  • 99.59 (n)
  • 100 (a)
C18orf25 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C24H18orf25 36
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C18orf25 36
  • 98 (a)
OneToOne
C7H18orf25 35
  • 95.46 (n)
  • 98.27 (a)
mouse
(Mus musculus)
Mammalia 8030462N17Rik 35
  • 92.23 (n)
  • 95.24 (a)
8030462N17Rik 16
8030462N17Rik 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C18orf25 36
  • 91 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C18orf25 36
  • 90 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1308601 35
  • 90.56 (n)
  • 93.98 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 56 (a)
OneToMany
-- 36
  • 86 (a)
OneToMany
CZH18ORF25 35
  • 82.38 (n)
  • 86.6 (a)
lizard
(Anolis carolinensis)
Reptilia C18orf25 36
  • 69 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia mgc12909-prov 35
tropical clawed frog
(Silurana tropicalis)
Amphibia c18orf25 35
  • 74.01 (n)
  • 80.51 (a)
Str.15922 35
zebrafish
(Danio rerio)
Actinopterygii C21H18orf25 36
  • 50 (a)
OneToOne
zgc:77838 35
  • 58.06 (n)
  • 58.67 (a)
Species with no ortholog for C18orf25:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C18orf25 Gene

ENSEMBL:
Gene Tree for C18orf25 (if available)
TreeFam:
Gene Tree for C18orf25 (if available)

Paralogs for C18orf25 Gene

Selected SIMAP similar genes for C18orf25 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for C18orf25 Gene

genes like me logo Genes that share paralogs with C18orf25: view

No data available for Paralogs for C18orf25 Gene

Variants for C18orf25 Gene

Sequence variations from dbSNP and Humsavar for C18orf25 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs3744857 -- 46,265,817(-) TGCTA(C/T)CAAAT utr-variant-3-prime
rs3744858 -- 46,265,306(-) AACAG(A/G)TCATG utr-variant-3-prime
rs3842397 -- 46,265,918(-) TAACC(-/AA)GTCAG utr-variant-3-prime
rs4315431 -- 46,174,640(+) GGGCC(A/G/T)GGTTG intron-variant
rs4335852 -- 46,186,788(+) caggc(A/G)tgagc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C18orf25 Gene

Variant ID Type Subtype PubMed ID
esv2675609 CNV Deletion 23128226
esv273961 CNV Insertion 20981092
nsv2278 CNV Insertion 18451855

Relevant External Links for C18orf25 Gene

HapMap Linkage Disequilibrium report
C18orf25

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C18orf25 Gene

Disorders for C18orf25 Gene

Relevant External Links for C18orf25

Human Genome Epidemiology (HuGE) Navigator
C18orf25
genes like me logo Genes that share disorders with C18orf25: view

No data available for UniProtKB/Swiss-Prot for C18orf25 Gene

Publications for C18orf25 Gene

  1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Candidate psychiatric illness genes identified in patients with pericentric inversions of chromosome 18. (PMID: 15722956) Pickard B.S. … Muir W.J. (Psychiatr. Genet. 2005) 2 3
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for C18orf25 Gene

Sources for C18orf25 Gene

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