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Aliases for C18orf25 Gene

Aliases for C18orf25 Gene

  • Chromosome 18 Open Reading Frame 25 2 3
  • ARKadia-Like 1 2 3
  • Uncharacterized Protein C18orf25 3
  • RNF111L1 3
  • ARKL1 3

External Ids for C18orf25 Gene

Previous GeneCards Identifiers for C18orf25 Gene

  • GC18P042049
  • GC18P043753
  • GC18P040611

Summaries for C18orf25 Gene

GeneCards Summary for C18orf25 Gene

C18orf25 (Chromosome 18 Open Reading Frame 25) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C18orf25 Gene

Genomics for C18orf25 Gene

Regulatory Elements for C18orf25 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C18orf25 Gene

46,173,553 bp from pter
46,266,992 bp from pter
93,440 bases
Plus strand

Genomic View for C18orf25 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C18orf25 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C18orf25 Gene

Proteins for C18orf25 Gene

  • Protein details for C18orf25 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C18orf25
    Protein Accession:
    Secondary Accessions:
    • A8K123
    • A8KAB6
    • Q5XG78
    • Q6N058
    • Q86TB5
    • Q8TCQ5

    Protein attributes for C18orf25 Gene

    403 amino acids
    Molecular mass:
    43324 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C18orf25 Gene


neXtProt entry for C18orf25 Gene

Proteomics data for C18orf25 Gene at MOPED

Post-translational modifications for C18orf25 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C18orf25 Gene

Antibody Products

No data available for DME Specific Peptides for C18orf25 Gene

Domains for C18orf25 Gene

Protein Domains for C18orf25 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C18orf25: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C18orf25 Gene

Function for C18orf25 Gene

Animal Model Products

CRISPR Products

miRNA for C18orf25 Gene

miRTarBase miRNAs that target C18orf25

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C18orf25

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for C18orf25 Gene

Localization for C18orf25 Gene

Subcellular locations from

Jensen Localization Image for C18orf25 Gene COMPARTMENTS Subcellular localization image for C18orf25 gene
Compartment Confidence
cytosol 2
nucleus 2
cytoskeleton 1
endoplasmic reticulum 1
extracellular 1
golgi apparatus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C18orf25 Gene

Pathways for C18orf25 Gene

SuperPathways for C18orf25 Gene

No Data Available

Interacting Proteins for C18orf25 Gene

Selected Interacting proteins: Q96B23-CR025_HUMAN for C18orf25 Gene via MINT I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for C18orf25 Gene


No data available for Pathways by source for C18orf25 Gene

Transcripts for C18orf25 Gene

Unigene Clusters for C18orf25 Gene

Chromosome 18 open reading frame 25:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C18orf25

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C18orf25 Gene

No ASD Table

Relevant External Links for C18orf25 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C18orf25 Gene

mRNA expression in normal human tissues for C18orf25 Gene

Protein differential expression in normal tissues for C18orf25 Gene

This gene is overexpressed in Lung (18.2), Testis (17.5), Retina (11.8), Blymphocyte (11.1), and Frontal cortex (6.8).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for C18orf25 Gene

SOURCE GeneReport for Unigene cluster for C18orf25 Gene Hs.116486

genes like me logo Genes that share expressions with C18orf25: view

Expression partners for C18orf25 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C18orf25 Gene

Orthologs for C18orf25 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C18orf25 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia C7H18orf25 35
  • 95.46 (n)
  • 98.27 (a)
C18orf25 36
  • 98 (a)
(Mus musculus)
Mammalia 8030462N17Rik 35
  • 92.23 (n)
  • 95.24 (a)
8030462N17Rik 16
8030462N17Rik 36
  • 95 (a)
(Pan troglodytes)
Mammalia C18H18orf25 35
  • 99.59 (n)
  • 100 (a)
C18orf25 36
  • 100 (a)
(Rattus norvegicus)
Mammalia RGD1308601 35
  • 90.56 (n)
  • 93.98 (a)
(Bos Taurus)
Mammalia C24H18orf25 36
  • 97 (a)
(Monodelphis domestica)
Mammalia C18orf25 36
  • 91 (a)
(Ornithorhynchus anatinus)
Mammalia C18orf25 36
  • 90 (a)
(Gallus gallus)
Aves CZH18ORF25 35
  • 82.38 (n)
  • 86.6 (a)
-- 36
  • 56 (a)
-- 36
  • 86 (a)
(Anolis carolinensis)
Reptilia C18orf25 36
  • 69 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c18orf25 35
  • 74.01 (n)
  • 80.51 (a)
Str.15922 35
African clawed frog
(Xenopus laevis)
Amphibia mgc12909-prov 35
(Danio rerio)
Actinopterygii zgc:77838 35
  • 58.06 (n)
  • 58.67 (a)
C21H18orf25 36
  • 50 (a)
Species with no ortholog for C18orf25:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C18orf25 Gene

Gene Tree for C18orf25 (if available)
Gene Tree for C18orf25 (if available)

Paralogs for C18orf25 Gene

(1) SIMAP similar genes for C18orf25 Gene using alignment to 3 proteins: Pseudogenes for C18orf25 Gene

genes like me logo Genes that share paralogs with C18orf25: view

No data available for Paralogs for C18orf25 Gene

Variants for C18orf25 Gene

Sequence variations from dbSNP and Humsavar for C18orf25 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs3744858 -- 46,265,306(-) AACAG(A/G)TCATG utr-variant-3-prime
rs4335852 -- 46,186,788(+) caggc(A/G)tgagc intron-variant
rs4566266 -- 46,196,717(+) AGCAA(A/C)TAACT intron-variant
rs4890315 -- 46,190,418(+) gggag(G/T)ctgag intron-variant
rs4890319 -- 46,232,678(+) CTGTT(A/T)GTTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C18orf25 Gene

Variant ID Type Subtype PubMed ID
esv2675609 CNV Deletion 23128226
esv273961 CNV Insertion 20981092
nsv2278 CNV Insertion 18451855

Relevant External Links for C18orf25 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C18orf25 Gene

Disorders for C18orf25 Gene

Relevant External Links for C18orf25

Human Genome Epidemiology (HuGE) Navigator

No disorders were found for C18orf25 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C18orf25 Gene

Publications for C18orf25 Gene

  1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Candidate psychiatric illness genes identified in patients with pericentric inversions of chromosome 18. (PMID: 15722956) Pickard B.S. … Muir W.J. (Psychiatr. Genet. 2005) 2 3
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for C18orf25 Gene

Sources for C18orf25 Gene

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