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Aliases for C18orf21 Gene

Aliases for C18orf21 Gene

  • Chromosome 18 Open Reading Frame 21 2 3
  • HBV X-Transactivated Gene 13 Protein 3 4
  • HBV XAg-Transactivated Protein 13 3 4
  • XTP13 3 4
  • HBV X-Transactivated Protein 13 3
  • UPF0711 Protein C18orf21 3
  • PNAS-124 3
  • PNAS-131 3
  • HsT3108 3

External Ids for C18orf21 Gene

Summaries for C18orf21 Gene

GeneCards Summary for C18orf21 Gene

C18orf21 (Chromosome 18 Open Reading Frame 21) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C18orf21 Gene

Genomics for C18orf21 Gene

Genomic Location for C18orf21 Gene

35,972,083 bp from pter
35,979,287 bp from pter
7,205 bases
Plus strand

Genomic View for C18orf21 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C18orf21 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C18orf21 Gene

Regulatory Elements for C18orf21 Gene

Proteins for C18orf21 Gene

  • Protein details for C18orf21 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0711 protein C18orf21
    Protein Accession:
    Secondary Accessions:
    • Q6GW03
    • Q9BXV6
    • Q9BXW2

    Protein attributes for C18orf21 Gene

    220 amino acids
    Molecular mass:
    24827 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAK07541.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAK07547.1; Type=Frameshift; Positions=216; Evidence={ECO:0000305};

    Alternative splice isoforms for C18orf21 Gene


neXtProt entry for C18orf21 Gene

Proteomics data for C18orf21 Gene at MOPED

Post-translational modifications for C18orf21 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C18orf21 Gene

Domains for C18orf21 Gene

Protein Domains for C18orf21 Gene



  • Belongs to the UPF0711 family.:
    • Q32NC0
genes like me logo Genes that share domains with C18orf21: view

No data available for Gene Families for C18orf21 Gene

Function for C18orf21 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C18orf21 Gene

Localization for C18orf21 Gene

Subcellular locations from

Jensen Localization Image for C18orf21 Gene COMPARTMENTS Subcellular localization image for C18orf21 gene
Compartment Confidence
nucleus 2
extracellular 1
golgi apparatus 1
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for C18orf21 Gene

Pathways for C18orf21 Gene

SuperPathways for C18orf21 Gene

No Data Available

Interacting Proteins for C18orf21 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000465517 for C18orf21 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for C18orf21 Gene


No data available for Pathways by source for C18orf21 Gene

Transcripts for C18orf21 Gene

Unigene Clusters for C18orf21 Gene

Chromosome 18 open reading frame 21:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C18orf21 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d
SP1: - - -
SP2: - -
SP4: -
SP5: -

Relevant External Links for C18orf21 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C18orf21 Gene

mRNA expression in normal human tissues for C18orf21 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C18orf21 Gene

SOURCE GeneReport for Unigene cluster for C18orf21 Gene Hs.37883

genes like me logo Genes that share expressions with C18orf21: view

Orthologs for C18orf21 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C18orf21 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C18H18orf21 36
  • 99.69 (n)
  • 99.08 (a)
C18ORF21 37
  • 99 (a)
(Bos Taurus)
Mammalia C18orf21 37
  • 85 (a)
C24H18orf21 36
  • 88.73 (n)
  • 86.85 (a)
(Canis familiaris)
Mammalia C18orf21 37
  • 84 (a)
C7H18orf21 36
  • 87.48 (n)
  • 84.98 (a)
(Mus musculus)
Mammalia 2700062C07Rik 36
  • 79.28 (n)
  • 74.77 (a)
2700062C07Rik 16
2700062C07Rik 37
  • 73 (a)
(Monodelphis domestica)
Mammalia -- 37
  • 52 (a)
-- 37
  • 51 (a)
(Ornithorhynchus anatinus)
Mammalia C18orf21 37
  • 49 (a)
(Rattus norvegicus)
Mammalia MGC116121 36
  • 79.28 (n)
  • 73.36 (a)
(Gallus gallus)
Aves C18ORF21 36
  • 60.79 (n)
  • 49.52 (a)
C18orf21 37
  • 48 (a)
(Anolis carolinensis)
Reptilia C18orf21 37
  • 40 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c18orf21 36
  • 54.07 (n)
  • 44.5 (a)
(Danio rerio)
Actinopterygii C19H18orf21 (1 of 2) 37
  • 33 (a)
C19H18orf21 (2 of 2) 37
  • 33 (a)
si:dkey-184p18.2 36
  • 46.14 (n)
  • 33.99 (a)
Species with no ortholog for C18orf21:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C18orf21 Gene

Gene Tree for C18orf21 (if available)
Gene Tree for C18orf21 (if available)

Paralogs for C18orf21 Gene Pseudogenes for C18orf21 Gene

genes like me logo Genes that share paralogs with C18orf21: view

No data available for Paralogs for C18orf21 Gene

Variants for C18orf21 Gene

Sequence variations from dbSNP and Humsavar for C18orf21 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs1540042 -- 35,975,273(+) GCTTA(C/T)TTTTA intron-variant
rs1786211 -- 35,973,720(+) gttcg(A/T)gacca intron-variant
rs1786230 -- 35,971,038(-) agtgt(G/T)aggat upstream-variant-2KB
rs2276314 - 35,977,503(+) CTCCT(A/G)CAAGT reference, missense, intron-variant
rs2298715 -- 35,972,462(+) GAAAC(C/T)CCGCT upstream-variant-2KB, utr-variant-5-prime

Relevant External Links for C18orf21 Gene

HapMap Linkage Disequilibrium report

No data available for Structural Variations from Database of Genomic Variants (DGV) for C18orf21 Gene

Disorders for C18orf21 Gene

No disorders were found for C18orf21 Gene.

No data available for UniProtKB/Swiss-Prot for C18orf21 Gene

Publications for C18orf21 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PMID: 16964243) Beausoleil S.A. … Gygi S.P. (Nat. Biotechnol. 2006) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for C18orf21 Gene

Sources for C18orf21 Gene

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