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Aliases for C17orf99 Gene

Aliases for C17orf99 Gene

  • Chromosome 17 Open Reading Frame 99 2 3
  • Uncharacterized Protein C17orf99 3
  • GLPG464 3
  • UNQ464 3

External Ids for C17orf99 Gene

Summaries for C17orf99 Gene

GeneCards Summary for C17orf99 Gene

C17orf99 (Chromosome 17 Open Reading Frame 99) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf99 Gene

Genomics for C17orf99 Gene

Genomic Location for C17orf99 Gene

Start:
78,146,353 bp from pter
End:
78,166,283 bp from pter
Size:
19,931 bases
Orientation:
Plus strand

Genomic View for C17orf99 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C17orf99 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf99 Gene

Regulatory Elements for C17orf99 Gene

Proteins for C17orf99 Gene

  • Protein details for C17orf99 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UX52-CQ099_HUMAN
    Recommended name:
    Uncharacterized protein C17orf99
    Protein Accession:
    Q6UX52
    Secondary Accessions:

    Protein attributes for C17orf99 Gene

    Size:
    265 amino acids
    Molecular mass:
    29091 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C17orf99 Gene

Proteomics data for C17orf99 Gene at MOPED

Post-translational modifications for C17orf99 Gene

  • Glycosylation at Asn86 and Asn132

Other Protein References for C17orf99 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C17orf99 Gene

Domains for C17orf99 Gene

Protein Domains for C17orf99 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf99: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf99 Gene

Function for C17orf99 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C17orf99 Gene

Localization for C17orf99 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C17orf99 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C17orf99 Gene COMPARTMENTS Subcellular localization image for C17orf99 gene
Compartment Confidence
extracellular 4
cytosol 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for C17orf99 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with C17orf99: view

Pathways for C17orf99 Gene

SuperPathways for C17orf99 Gene

No Data Available

Interacting Proteins for C17orf99 Gene

Gene Ontology (GO) - Biological Process for C17orf99 Gene

None

No data available for Pathways by source for C17orf99 Gene

Transcripts for C17orf99 Gene

mRNA/cDNA for C17orf99 Gene

(3) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C17orf99 Gene

Chromosome 17 open reading frame 99:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf99 Gene

ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b
SP1: -
SP2: -
SP3:

Relevant External Links for C17orf99 Gene

GeneLoc Exon Structure for
C17orf99
ECgene alternative splicing isoforms for
C17orf99

Expression for C17orf99 Gene

mRNA expression in normal human tissues for C17orf99 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C17orf99 Gene

This gene is overexpressed in Whole Blood (8.3).

SOURCE GeneReport for Unigene cluster for C17orf99 Gene Hs.633034

genes like me logo Genes that share expressions with C17orf99: view

No data available for Protein expression and mRNA Expression by UniProt/SwissProt for C17orf99 Gene

Orthologs for C17orf99 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C17orf99 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf99 35
  • 97.99 (n)
  • 95.47 (a)
C17orf99 36
  • 63 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C17orf99 36
  • 55 (a)
OneToOne
C9H17orf99 35
  • 77.14 (n)
  • 62.3 (a)
mouse
(Mus musculus)
Mammalia 6030468B19Rik 35
  • 70.35 (n)
  • 57.21 (a)
6030468B19Rik 16
6030468B19Rik 36
  • 48 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C17orf99 36
  • 43 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC688282 35
  • 68.25 (n)
  • 56.32 (a)
Species with no ortholog for C17orf99:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf99 Gene

ENSEMBL:
Gene Tree for C17orf99 (if available)
TreeFam:
Gene Tree for C17orf99 (if available)

Paralogs for C17orf99 Gene

No data available for Paralogs for C17orf99 Gene

Variants for C17orf99 Gene

Sequence variations from dbSNP and Humsavar for C17orf99 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs560 -- 78,166,054(+) TGAAC(C/T)GTCCA utr-variant-3-prime
rs3642 -- 78,166,097(-) GTGCA(C/T)GCTGA utr-variant-3-prime
rs3644 -- 78,166,053(-) GGACG(A/G)TTCAT utr-variant-3-prime
rs748708 -- 78,146,714(-) TTGCG(C/T)CCCTC intron-variant
rs2004339 -- 78,145,822(+) ATGGA(A/G)TCTCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C17orf99 Gene

Variant ID Type Subtype PubMed ID
nsv833554 CNV Gain+Loss 17160897
nsv908860 CNV Loss 21882294
dgv3275n71 CNV Loss 21882294
dgv3276n71 CNV Loss 21882294
dgv3277n71 CNV Loss 21882294
dgv3278n71 CNV Loss 21882294
nsv908871 CNV Loss 21882294
nsv470607 CNV Loss 18288195
nsv908872 CNV Gain 21882294
dgv3279n71 CNV Loss 21882294

Relevant External Links for C17orf99 Gene

HapMap Linkage Disequilibrium report
C17orf99

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf99 Gene

Disorders for C17orf99 Gene

No disorders were found for C17orf99 Gene.

No data available for UniProtKB/Swiss-Prot for C17orf99 Gene

Publications for C17orf99 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  2. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PMID: 15340161) Zhang Z. … Henzel W.J. (Protein Sci. 2004) 3 4
  3. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4
  4. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3

Products for C17orf99 Gene

Sources for C17orf99 Gene

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