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Aliases for C17orf97 Gene

Aliases for C17orf97 Gene

  • Chromosome 17 Open Reading Frame 97 2 3
  • Ligand Of ATE1 Protein 3 4
  • LIAT1 3 4
  • Protein LIAT1 3

External Ids for C17orf97 Gene

Previous GeneCards Identifiers for C17orf97 Gene

  • GC17P000261

Summaries for C17orf97 Gene

GeneCards Summary for C17orf97 Gene

C17orf97 (Chromosome 17 Open Reading Frame 97) is a Protein Coding gene.

UniProtKB/Swiss-Prot for C17orf97 Gene

  • May be involved in ATE1-mediated N-terminal arginylation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf97 Gene

Genomics for C17orf97 Gene

Regulatory Elements for C17orf97 Gene

Genomic Location for C17orf97 Gene

410,327 bp from pter
423,719 bp from pter
13,393 bases
Plus strand

Genomic View for C17orf97 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C17orf97 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf97 Gene

Proteins for C17orf97 Gene

  • Protein details for C17orf97 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein LIAT1
    Protein Accession:
    Secondary Accessions:
    • A5D8T6
    • Q6NSI2
    • Q6PFW9

    Protein attributes for C17orf97 Gene

    453 amino acids
    Molecular mass:
    49656 Da
    Quaternary structure:
    • Interacts with ATE1; it is not a substrate of LIAT1. Interacts with JMJD6 and MRPS14 (By similarity).

    Alternative splice isoforms for C17orf97 Gene


neXtProt entry for C17orf97 Gene

Proteomics data for C17orf97 Gene at MOPED

Post-translational modifications for C17orf97 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf97 Gene

Antibody Products

No data available for DME Specific Peptides for C17orf97 Gene

Domains for C17orf97 Gene

Protein Domains for C17orf97 Gene


Graphical View of Domain Structure for InterPro Entry



  • Q6ZQX7
  • LIAT1 proteins of some primates, from macaques to humans, contain tandem repeats of a 10-residue sequence, whereas LIAT1 proteins of other mammals contain a single copy of this motif. Quantities of these repeats are, in general, different in LIAT1 of different primates. For example, there are 1, 4, 13, 13, 17, and 17 repeats in the gibbon, gorilla, orangutan, bonobo, neanderthal, and human LIAT1, respectively.
genes like me logo Genes that share domains with C17orf97: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for C17orf97 Gene

Function for C17orf97 Gene

Molecular function for C17orf97 Gene

UniProtKB/Swiss-Prot Function:
May be involved in ATE1-mediated N-terminal arginylation.

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C17orf97

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C17orf97 Gene

Localization for C17orf97 Gene

Subcellular locations from

Jensen Localization Image for C17orf97 Gene COMPARTMENTS Subcellular localization image for C17orf97 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C17orf97 Gene

Pathways for C17orf97 Gene

SuperPathways for C17orf97 Gene

No Data Available

Interacting Proteins for C17orf97 Gene

Gene Ontology (GO) - Biological Process for C17orf97 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016598 protein arginylation ISS --
genes like me logo Genes that share ontologies with C17orf97: view

No data available for Pathways by source for C17orf97 Gene

Transcripts for C17orf97 Gene

mRNA/cDNA for C17orf97 Gene

Unigene Clusters for C17orf97 Gene

Chromosome 17 open reading frame 97:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C17orf97

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf97 Gene

No ASD Table

Relevant External Links for C17orf97 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C17orf97 Gene

mRNA expression in normal human tissues for C17orf97 Gene

mRNA differential expression in normal tissues according to GTEx for C17orf97 Gene

This gene is overexpressed in Testis (11.8).

Protein differential expression in normal tissues for C17orf97 Gene

This gene is overexpressed in Testis (35.3), Ovary (19.2), and Blymphocyte (14.5).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C17orf97 Gene

SOURCE GeneReport for Unigene cluster for C17orf97 Gene Hs.499607

genes like me logo Genes that share expressions with C17orf97: view

Expression partners for C17orf97 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C17orf97 Gene

Orthologs for C17orf97 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C17orf97 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C19H17orf97 35
  • 73.62 (n)
  • 64.17 (a)
C17orf97 36
  • 68 (a)
(Canis familiaris)
Mammalia C9H17orf97 35
  • 75.25 (n)
  • 66.29 (a)
C17orf97 36
  • 69 (a)
(Mus musculus)
Mammalia 1700016K19Rik 35
  • 74.59 (n)
  • 66.83 (a)
1700016K19Rik 16
1700016K19Rik 36
  • 62 (a)
(Pan troglodytes)
Mammalia C17H17orf97 35
  • 96.79 (n)
  • 95.19 (a)
C17orf97 36
  • 95 (a)
(Rattus norvegicus)
Mammalia RGD1565611 35
  • 73.43 (n)
  • 65.84 (a)
Species with no ortholog for C17orf97:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf97 Gene

Gene Tree for C17orf97 (if available)
Gene Tree for C17orf97 (if available)

Paralogs for C17orf97 Gene

No data available for Paralogs for C17orf97 Gene

Variants for C17orf97 Gene

Sequence variations from dbSNP and Humsavar for C17orf97 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs4581766 - 410,508(+) AGGAG(A/G)AGGAG missense, reference
rs7209967 -- 409,496(+) ggtaa(C/G)ggaca upstream-variant-2KB
rs7214038 -- 409,571(+) AAAGT(A/G)GAAAA upstream-variant-2KB
rs7502594 -- 410,391(+) GCCGA(C/T)TAGTC synonymous-codon, reference
rs7503725 -- 410,351(+) GAGAC(G/T)CGTGG reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for C17orf97 Gene

Variant ID Type Subtype PubMed ID
nsv907452 CNV Gain 21882294
nsv457627 CNV Gain 19166990
esv2422420 CNV Duplication 17116639
nsv827849 CNV Gain 20364138
esv2715298 CNV Deletion 23290073
esv2715301 CNV Deletion 23290073
esv2715302 CNV Deletion 23290073
esv998391 CNV Deletion 20482838
esv1210692 CNV Deletion 17803354

Relevant External Links for C17orf97 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf97 Gene

Disorders for C17orf97 Gene

No disorders were found for C17orf97 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for C17orf97 Gene

Publications for C17orf97 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 3
  3. Identification of new mechanisms of cellular response to chemotherapy by tracking changes in post-translational modifications by ubiquitin and ubiquitin-like proteins. (PMID: 24654937) Bonacci T. … Soubeyran P. (J. Proteome Res. 2014) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for C17orf97 Gene

Sources for C17orf97 Gene

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