C17orf80 Gene
protein-coding GIFtS: 40
GCID: GC17P071228
|
|
chromosome 17 open reading frame 80
| |
Aliases
for C17orf80 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 17 Open Reading Frame 801 2 | | FLJ207211 | | HLC-81 2 3 | | Lung Cancer-Related Protein 82 | | MIG31 2 | | Migration-Inducing Protein 32 | | SPEP11 2 | | Sperm-Expressed Protein 12 | | Cell Migration-Inducing Gene 3 Protein2 3 | | Uncharacterized Protein C17orf802 | | Human Lung Cancer Oncogene 8 Protein2 3 | | |
Export aliases for C17orf80 gene to outside databasesPrevious GC identifers: GC17P068741 GC17P066637 |
Summaries
for C17orf80 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C17orf80 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C17orf80 gene promoter:
AML1a MEF-2 STAT1beta MyoD Nkx2-5 C/EBPalpha GATA-2 MEF-2A aMEF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for C17orf80
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C17orf80 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25.1 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.1C17orf80 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P071228: view genomic region
(about GC identifiers)
Start:
|
71,228,372 bp from pter |
End:
|
71,245,098 bp from pter |
Size:
|
16,727 bases |
Orientation:
|
plus strand |
|
Proteins
for C17orf80 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CQ080_HUMAN, Q9BSJ5 (See
protein sequence)Recommended Name: Uncharacterized protein C17orf80 Size: 609 amino acids; 67315 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Sequence caution: Sequence=AAP72185.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAA91344.1; Type=Frameshift; Positions=121; Sequence=BAB15680.1; Type=Erroneous initiation; Note=TranslationN-terminally extended;
Secondary accessions: A8K9X3 Q5JB45 Q6YAU3 Q9H0L9 Q9H5E6 Q9NWN5Alternative splicing: 3 isoforms: Q9BSJ5-1 Q9BSJ5-2 Q9BSJ5-3 Explore the universe of human proteins at neXtProt for C17orf80: NX_Q9BSJ5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BSJ5
C17orf80 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001094091.1 NP_001094092.1 NP_060411.2
ENSEMBL proteins: ENSP00000255557 ENSP00000464132 ENSP00000462818 ENSP00000268942 ENSP00000396970 ENSP00000463019 ENSP00000440551 ENSP00000463718 ENSP00000351937
Human Recombinant Protein Products for C17orf80:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
C17orf80 for ontologies About GeneDecksing
C17orf80 Antibody Products:
Assay Products for C17orf80: |
Protein
Domains /
Families
for C17orf80 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9BSJ5 |
Function
for C17orf80 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
1 GenomeRNAi human phenotype for C17orf80:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C17orf80 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C17orf80 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): C17orf80 (NM_001100621) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C17orf80 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C17orf80 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C17orf80 |
|
Pathways & Interactions
for C17orf80 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C17orf80
|
Drugs & Compounds
for C17orf80 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C17orf80
Search CenterWatch for drugs/clinical trials and news about C17orf80 / CQ080
|
Transcripts
for C17orf80 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C17orf80 gene (3 alternative transcripts): NM_001100621.1 NM_001100622.1 NM_017941.4 Unigene Cluster for C17orf80: Chromosome 17 open reading frame 80 Hs.12929 [show with all ESTs]Unigene Representative Sequence: NM_0179419 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000255557(uc010wqu.1) ENST00000577615 ENST00000585109 ENST00000268942
ENST00000426147(uc002jjk.1) ENST00000582391 ENST00000535032 ENST00000582793
ENST00000359042(uc010dfj.3 uc002jjm.4 uc002jjl.4)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C17orf80 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C17orf80 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): C17orf80 (NM_001100621) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C17orf80 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C17orf80 |
Additional cDNA sequence: AK000728.1 AK027166.1 AK292838.1 AK301905.1 AL136740.1 AY163812.1 AY239293.1 BC005005.2 11 DOTS entries: DT.100751259 DT.95269182 DT.100754745 DT.95287897 DT.102825595 DT.120979055 DT.120979096 DT.423629 DT.443604 DT.95226482 DT.95269183 24/143 AceView cDNA sequences (see all 143): CB134766 F09792 BE328463 AW473463 AA722641 BQ018309 CR612666 BU194891 AW576319 AI910475 H84336 NM_017941 AA295241 BM475559 BU736238 AA908931 BC005005 AI277508 AA400677 BU788930 AA308552 BE880514 AA334979 BX348208
GeneLoc Exon Structure
|
Expression
for C17orf80 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C17orf80 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTGAATACC
About this image
See C17orf80 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C17orf80
SOURCE GeneReport for Unigene cluster: Hs.12929
SABiosciences Custom PCR Arrays for C17orf80
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C17orf80
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C17orf80 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C17orf80 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C17orf80 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C17orf80 |
Orthologs
for C17orf80 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C17orf80 gene from 1/7 species (see all 7) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
D11Wsu47e1 , 5 |
DNA segment, Chr 11, Wayne State University 47, expressed1, 5 |
65.94(n)1
50.36(a)1 |
|
11 (79.15 cM)5
2768521 NM_177777.51 NP_808445.21
1136844125 |
ENSEMBL Gene Tree for C17orf80 (if available)
TreeFam Gene Tree for C17orf80 (if available) |
Paralogs
for C17orf80 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C17orf80 gene
C17orf80 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for C17orf80
PGOHUM00000240409
|
Genomic Variants
for C17orf80 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C17orf80 (71228372 - 71245098 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C17orf80: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C17orf80 |
|
Disorders
/ Diseases
for C17orf80 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C17orf80 for disorders About GeneDecksing
4  diseases for C17orf80: About MalaCardslung cancer postpoliomyelitis syndrome poliomyelitis parkinson's disease
1 disease from the University of Copenhagen DISEASES database for C17orf80:Poliomyelitis Export disorders for C17orf80 gene to outside databases
|
Publications
for C17orf80 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C17orf80 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with C17orf80) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
- Identification of genes related to Parkinson's disease using expressed sequence tags. (PubMed id 17213182)1 Kim J.M....Kim N.S. (2006)
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- DNA cloning using in vitro site-specific recombination. (PubMed id 11076863)1 Hartley J.L....Brasch M.A. (2000)
|
External Searches for C17orf80 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C17orf80 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C17orf80 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C17orf80 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C17orf80 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C17orf80 gene:
Search GeneIP for patents involving C17orf80
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C17orf80 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C17orf80 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C17orf80 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C17orf80 | | | OriGene Protein Over-expression Lysate for C17orf80 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C17orf80 | | OriGene 3'-UTR Clone for C17orf80 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C17orf80 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C17orf80 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C17orf80 | | OriGene Custom Protein Services for C17orf80 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C17orf80 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C17orf80 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C17orf80 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C17orf80 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C17orf80 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C17orf80 |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | | C17orf80 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C17orf80 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for C17orf80 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C17orf80 |
| |  | |
|
|
|
