Aliases for C17orf80 Gene
Aliases for C17orf80 Gene
External Ids for C17orf80 Gene
- HGNC: 29601
- Entrez Gene: 55028
- Ensembl: ENSG00000141219
- UniProtKB: Q9BSJ5
Previous GeneCards Identifiers for C17orf80 Gene
- GC17P068741
- GC17P071228
- GC17P066637
Summaries for C17orf80 Gene
GeneCards Summary for C17orf80 Gene
C17orf80 (Chromosome 17 Open Reading Frame 80) is a Protein Coding gene.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf80 Gene
Genomics for C17orf80 Gene
Regulatory Elements for C17orf80 Gene
Enhancers for C17orf80 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH17F073189 | 1.2 | Ensembl ENCODE | 26.1 | -42.5 | -42533 | 0.6 | ELF3 PKNOX1 ARID4B SIN3A ZNF48 RAD21 RARA SLC30A9 SCRT2 ZNF143 | C17orf80 SSTR2 FAM104A CDC42EP4 COG1 GC17P073175 |
| GH17F073191 | 1.1 | ENCODE | 26.5 | -39.4 | -39416 | 2.8 | WRNIP1 ZFP64 ARID4B SIN3A DMAP1 YY1 ZNF143 FOS SP3 SP5 | C17orf80 SSTR2 FAM104A CDC42EP4 COG1 ENSG00000277728 |
| GH17F073286 | 2 | VISTA FANTOM5 Ensembl ENCODE | 11.2 | +59.0 | 59031 | 8.7 | HDGF PKNOX1 MLX WRNIP1 ARID4B SIN3A DMAP1 YY1 SLC30A9 FOS | CDC42EP4 CPSF4L FAM104A C17orf80 GC17P073281 GC17M073288 |
| GH17F073202 | 1.4 | FANTOM5 Ensembl ENCODE | 14.6 | -28.5 | -28450 | 2.3 | ELF3 PKNOX1 ARID4B DMAP1 RARA CREM MIXL1 THAP11 NFYC USF2 | C17orf80 COG1 ENSG00000277728 GC17M073210 PIR44468 |
| GH17F073230 | 1.1 | ENCODE | 16.9 | -0.1 | -79 | 3.1 | HDGF CREB3L1 MLX WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 | C17orf80 COG1 GC17M073213 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C17orf80 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the C17orf80 gene promoter:
Regulatory Element Products
Genomic Location for C17orf80 Gene
- Chromosome:
- 17
- Start:
- 73,232,233 bp from pter
- End:
- 73,248,959 bp from pter
- Size:
- 16,727 bases
- Orientation:
- Plus strand
Genomic View for C17orf80 Gene
Genes around C17orf80 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.1 by Ensembl
- 17q25.1 by Entrez Gene
- 17q25.1 by HGNC
C17orf80 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C17orf80 Gene
Proteins for C17orf80 Gene
-
Protein details for C17orf80 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BSJ5-CQ080_HUMAN
- Recommended name:
- Uncharacterized protein C17orf80
- Protein Accession:
- Q9BSJ5
- A8K9X3
- Q5JB45
- Q6YAU3
- Q9H0L9
- Q9H5E6
- Q9NWN5
Protein attributes for C17orf80 Gene
- Size:
- 609 amino acids
- Molecular mass:
- 67315 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAP72185.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAA91344.1; Type=Frameshift; Positions=121; Evidence={ECO:0000305}; Sequence=BAB15680.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for C17orf80 Gene
Post-translational modifications for C17orf80 Gene
Other Protein References for C17orf80 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for C17orf80
- Novus Biologicals Antibodies for C17orf80
-
Abcam antibodies for C17orf80
- Invitrogen Antibodies for C17orf80
- GeneTex C17orf80 antibody for C17orf80
Protein Products
-
OriGene Purified Proteins for C17orf80
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- Origene Custom Protein Services for C17orf80
- Search GeneTex for Proteins for C17orf80
Assay Products
No data available for DME Specific Peptides for C17orf80 Gene
Domains & Families for C17orf80 Gene
Protein Domains for C17orf80 Gene
- ProtoNet:
Suggested Antigen Peptide Sequences for C17orf80 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for C17orf80 Gene
Function for C17orf80 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
Phenotypes for C17orf80 Gene
- GenomeRNAi human phenotypes for C17orf80:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for C17orf80
-
-
ViGene Biosciences lentiviral particle packaged cDNA for C17orf80 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C17orf80 gene
- Search ViGene Biosciences for C17orf80
CRISPR Products
-
OriGene CRISPR knockouts for C17orf80
- GenScript: Design CRISPR guide RNA sequences for C17orf80
miRNA for C17orf80 Gene
- miRTarBase miRNAs that target C17orf80
-
- hsa-mir-15a-5p (MIRT003881)
- hsa-mir-16-5p (MIRT004375)
- hsa-mir-155-5p (MIRT020493)
- hsa-mir-125a-5p (MIRT045779)
- hsa-mir-125b-5p (MIRT046098)
- hsa-mir-3658 (MIRT446225)
- hsa-mir-580-3p (MIRT446226)
- hsa-mir-6864-5p (MIRT446227)
- hsa-mir-6126 (MIRT446228)
- hsa-mir-526b-5p (MIRT446229)
- hsa-mir-3653-3p (MIRT446230)
- hsa-mir-539-5p (MIRT446231)
- hsa-mir-1252-5p (MIRT446232)
- hsa-mir-4635 (MIRT446233)
- hsa-mir-8083 (MIRT446234)
- hsa-mir-5197-3p (MIRT446235)
miRNA Products
- Search ViGene Biosciences for C17orf80
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for C17orf80
- Browse OriGene Inhibitory RNA Products For C17orf80
-
ViGene Biosciences ready-to-package AAV shRNAs for C17orf80 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C17orf80
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C17orf80
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for C17orf80
-
ViGene Biosciences adenoviral particle packaged cDNA for C17orf80 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for C17orf80 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C17orf80 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf80 Gene
Localization for C17orf80 Gene
Subcellular locations from UniProtKB/Swiss-Prot for C17orf80 Gene
- Membrane; Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 3 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0070062 | extracellular exosome | IDA | 19056867 |
Pathways & Interactions for C17orf80 Gene
No Data Available
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008150 | biological_process | ND | -- |
No data available for Pathways by source and SIGNOR curated interactions for C17orf80 Gene
Transcripts for C17orf80 Gene
mRNA/cDNA for C17orf80 Gene
- (10) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (143) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C17orf80 Gene
CRISPR Products
-
OriGene CRISPR knockouts for C17orf80
- GenScript: Design CRISPR guide RNA sequences for C17orf80
miRNA Products
- Search ViGene Biosciences for C17orf80
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for C17orf80
- Browse OriGene Inhibitory RNA Products For C17orf80
-
ViGene Biosciences ready-to-package AAV shRNAs for C17orf80 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C17orf80
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C17orf80
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for C17orf80 Gene
mRNA differential expression in normal tissues according to GTEx for C17orf80 Gene
This gene is overexpressed in Testis (x5.0).
This gene is overexpressed in Kidney (25.6), Liver (13.8), Lung (6.9), and Breast (6.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C17orf80 Gene
NURSA nuclear receptor signaling pathways regulating expression of C17orf80 Gene:
C17orf80SOURCE GeneReport for Unigene cluster for C17orf80 Gene:
Hs.12929Primer Products
-
OriGene qPCR primer pairs for C17orf80
-
OriGene qPCR primer pairs and template standards for C17orf80
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C17orf80 Gene
Orthologs for C17orf80 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C17H17orf80 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | C9H17orf80 34 |
|
||
| C17orf80 35 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | C19H17orf80 34 |
|
||
| C17orf80 35 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | D11Wsu47e 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | MGC95210 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | C17orf80 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | C17orf80 35 |
|
OneToOne |
- Species where no ortholog for C17orf80 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C17orf80 Gene
Pseudogenes.org Pseudogenes for C17orf80 Gene
No data available for Paralogs for C17orf80 Gene
Variants for C17orf80 Gene
| SNP ID | Clin | Chr 17 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs776418014 | Uncertain significance | 73,236,455(+) | AGGAA(C/T)GGACT | intron-variant, reference, missense | |
| rs10673450 | -- | 73,235,127(+) | GAGAC(-/AA)GAGAA | intron-variant | |
| rs10701263 | -- | 73,234,321(+) | TTTTT(-/T/TT/TTT)AATTT | intron-variant, upstream-variant-2KB | |
| rs111267869 | -- | 73,243,549(+) | TTGTC(-/T)TTTTT | intron-variant | |
| rs111938303 | -- | 73,234,799(+) | TATGC(A/C)TATTA | intron-variant |
Residual Variation Intolerance Score:
90% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.74;
57.71% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C17orf80 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C17orf80
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf80 Gene
Disorders for C17orf80 Gene
Relevant External Links for C17orf80
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- C17orf80
No disorders were found for C17orf80 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf80 Gene
Publications for C17orf80 Gene
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4 64
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
- Large-scale proteomics and phosphoproteomics of urinary exosomes. (PMID: 19056867) Gonzales P.A. … Knepper M.A. (J. Am. Soc. Nephrol. 2009) 3 64
- Subproteome analysis of the neutrophil cytoskeleton. (PMID: 19294702) Xu P. … Radulovic M. (Proteomics 2009) 22 64
Products for C17orf80 Gene
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- Custom Antibody ServicesOriGene Antibodies for C17orf80
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- OriGene qPCR primer pairs and template standards for C17orf80
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- Novus Biologicals Antibodies for C17orf80
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- ViGene Biosciences adenoviral particle packaged cDNA for C17orf80 gene
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- Cyagen custom Knockout/knockin (KOKI) mouse models for C17orf80
- VectorBuilder custom plasmid, inducible vectors for C17orf80
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C17orf80
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C17orf80 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab