C17orf78 Gene
protein-coding GIFtS: 37
GCID: GC17P035732
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chromosome 17 open reading frame 78
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Aliases
for C17orf78 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 17 Open Reading Frame 781 2 | | FLJ396471 | | Uncharacterized Protein C17orf782 |
Export aliases for C17orf78 gene to outside databasesPrevious GC identifers: GC17P032808 GC17P031670 |
Summaries
for C17orf78 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C17orf78 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C17orf78 gene promoter:
C/EBPbeta AP-1 ATF-2 GATA-2 CREB E2F-1 E2F deltaCREB Cart-1 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for C17orf78
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C17orf78 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q12 Ensembl cytogenetic band: 17q12 HGNC cytogenetic band: 17q12C17orf78 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P035732: view genomic region
(about GC identifiers)
Start:
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35,732,928 bp from pter |
End:
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35,749,662 bp from pter |
Size:
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16,735 bases |
Orientation:
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plus strand |
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Proteins
for C17orf78 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CQ078_HUMAN, Q8N4C9 (See
protein sequence)Recommended Name: Uncharacterized protein C17orf78 Size: 275 amino acids; 30555 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Secondary accessions: Q8N8D2Alternative splicing: 2 isoforms: Q8N4C9-1 Q8N4C9-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for C17orf78: NX_Q8N4C9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N4C9
C17orf78 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_775896.3
ENSEMBL proteins: ENSP00000465605 ENSP00000300618
Human Recombinant Protein Products for C17orf78:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
C17orf78 for ontologies About GeneDecksing
C17orf78 Antibody Products:
Assay Products for C17orf78: |
Protein
Domains /
Families
for C17orf78 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8N4C9 |
Function
for C17orf78 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C17orf78 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C17orf78
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C17orf78 (NM_173625) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C17orf78 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C17orf78 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C17orf78 |
|
Pathways & Interactions
for C17orf78 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C17orf78
|
Drugs & Compounds
for C17orf78 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C17orf78
Search CenterWatch for drugs/clinical trials and news about C17orf78 / CQ078
|
Transcripts
for C17orf78 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C17orf78 gene: NM_173625.3 Unigene Cluster for C17orf78: Chromosome 17 open reading frame 78 Hs.439154 [show with all ESTs]Unigene Representative Sequence: NM_1736252 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000586700 ENST00000300618(uc010cva.1 uc002hns.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C17orf78 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C17orf78
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C17orf78 (NM_173625) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C17orf78 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C17orf78 |
Additional cDNA sequence: AK096966.1 BC034672.1 4 DOTS entries: DT.95088097 DT.100735863 DT.100804380 DT.91927622 4 AceView cDNA sequences: NM_173625 BC034672 BI759994 AK096966
GeneLoc Exon Structure
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Expression
for C17orf78 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C17orf78 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATCTATCCA
About this image
See C17orf78 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C17orf78
SOURCE GeneReport for Unigene cluster: Hs.439154
SABiosciences Custom PCR Arrays for C17orf78
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C17orf78
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C17orf78 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C17orf78 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C17orf78 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C17orf78 |
Orthologs
for C17orf78 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C17orf78 gene from 1/6 species (see all 6) About this table
ENSEMBL Gene Tree for C17orf78 (if available)
TreeFam Gene Tree for C17orf78 (if available) |
Paralogs
for C17orf78 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C17orf78 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for C17orf78
2 CNVs: 4033 7156
1 Inversion: 37189 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for C17orf78 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 C17orf78 for disorders About MalaCards
C17orf78 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: C17orf78 (3 documents)
Export disorders for C17orf78 gene to outside databases
|
Publications
for C17orf78 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C17orf78 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C17orf78) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (2004)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for C17orf78 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing C17orf78 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C17orf78 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C17orf78 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C17orf78 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C17orf78 gene:
Search GeneIP for patents involving C17orf78
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C17orf78 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C17orf78 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C17orf78 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C17orf78 | | | OriGene Protein Over-expression Lysate for C17orf78 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C17orf78 | | OriGene 3'-UTR Clone for C17orf78 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C17orf78 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C17orf78 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C17orf78 | | OriGene Custom Protein Services for C17orf78 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C17orf78 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C17orf78 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C17orf78 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C17orf78 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C17orf78 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C17orf78 |
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 | | | C17orf78 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C17orf78 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for C17orf78 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C17orf78 |
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