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Aliases for C17orf78 Gene

Aliases for C17orf78 Gene

  • Chromosome 17 Open Reading Frame 78 2 3

External Ids for C17orf78 Gene

Previous GeneCards Identifiers for C17orf78 Gene

  • GC17P032808
  • GC17P035732
  • GC17P031670

Summaries for C17orf78 Gene

GeneCards Summary for C17orf78 Gene

C17orf78 (Chromosome 17 Open Reading Frame 78) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf78 Gene

Genomics for C17orf78 Gene

Regulatory Elements for C17orf78 Gene

Genomic Location for C17orf78 Gene

Chromosome:
17
Start:
37,375,935 bp from pter
End:
37,392,708 bp from pter
Size:
16,774 bases
Orientation:
Plus strand

Genomic View for C17orf78 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C17orf78 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf78 Gene

Proteins for C17orf78 Gene

  • Protein details for C17orf78 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N4C9-CQ078_HUMAN
    Recommended name:
    Uncharacterized protein C17orf78
    Protein Accession:
    Q8N4C9
    Secondary Accessions:
    • Q8N8D2

    Protein attributes for C17orf78 Gene

    Size:
    275 amino acids
    Molecular mass:
    30555 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C17orf78 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C17orf78 Gene

Proteomics data for C17orf78 Gene at MOPED

Post-translational modifications for C17orf78 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf78 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C17orf78 Gene

Domains & Families for C17orf78 Gene

Protein Domains for C17orf78 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf78: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf78 Gene

Function for C17orf78 Gene

Phenotypes for C17orf78 Gene

GenomeRNAi human phenotypes for C17orf78:
genes like me logo Genes that share phenotypes with C17orf78: view

Animal Model Products

CRISPR Products

miRNA for C17orf78 Gene

miRTarBase miRNAs that target C17orf78

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C17orf78

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf78 Gene

Localization for C17orf78 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C17orf78 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for C17orf78 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C17orf78: view

No data available for Subcellular locations from COMPARTMENTS for C17orf78 Gene

Pathways & Interactions for C17orf78 Gene

SuperPathways for C17orf78 Gene

No Data Available

Interacting Proteins for C17orf78 Gene

Gene Ontology (GO) - Biological Process for C17orf78 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C17orf78 Gene

Drugs & Compounds for C17orf78 Gene

No Compound Related Data Available

Transcripts for C17orf78 Gene

mRNA/cDNA for C17orf78 Gene

(9) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C17orf78 Gene

Chromosome 17 open reading frame 78:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C17orf78

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf78 Gene

No ASD Table

Relevant External Links for C17orf78 Gene

GeneLoc Exon Structure for
C17orf78
ECgene alternative splicing isoforms for
C17orf78

Expression for C17orf78 Gene

mRNA expression in normal human tissues for C17orf78 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C17orf78 Gene

This gene is overexpressed in Small Intestine - Terminal Ileum (x44.0).

SOURCE GeneReport for Unigene cluster for C17orf78 Gene Hs.439154

genes like me logo Genes that share expression patterns with C17orf78: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C17orf78 Gene

Orthologs for C17orf78 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C17orf78 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C19H17orf78 35
  • 81.87 (n)
  • 69.71 (a)
dog
(Canis familiaris)
Mammalia C9H17orf78 35
  • 85.21 (n)
  • 76.36 (a)
mouse
(Mus musculus)
Mammalia Gm11437 35
  • 78.19 (n)
  • 64.34 (a)
Gm11437 16
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf78 35
  • 98.67 (n)
  • 97.82 (a)
rat
(Rattus norvegicus)
Mammalia LOC102552988 35
  • 77.57 (n)
  • 67.65 (a)
Species with no ortholog for C17orf78:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf78 Gene

ENSEMBL:
Gene Tree for C17orf78 (if available)
TreeFam:
Gene Tree for C17orf78 (if available)

Paralogs for C17orf78 Gene

No data available for Paralogs for C17orf78 Gene

Variants for C17orf78 Gene

Sequence variations from dbSNP and Humsavar for C17orf78 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
VAR_034877 -

Structural Variations from Database of Genomic Variants (DGV) for C17orf78 Gene

Variant ID Type Subtype PubMed ID
dgv955e1 CNV Complex 17122850
esv32692 CNV Loss 17666407
esv2667392 CNV Deletion 23128226

Variation tolerance for C17orf78 Gene

Residual Variation Intolerance Score: 64.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.28; 70.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C17orf78 Gene

HapMap Linkage Disequilibrium report
C17orf78

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf78 Gene

Disorders for C17orf78 Gene

Relevant External Links for C17orf78

Human Genome Epidemiology (HuGE) Navigator
C17orf78
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C17orf78
genes like me logo Genes that share disorders with C17orf78: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf78 Gene

Publications for C17orf78 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 67
  2. Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus. (PMID: 24999842) Garner C. … Neuhausen S.L. (PLoS ONE 2014) 67
  3. GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. (PMID: 23535730) Pharoah P.D. … Sellers T.A. (Nat. Genet. 2013) 67
  4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 67
  5. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 67

Products for C17orf78 Gene

Sources for C17orf78 Gene

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