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Aliases for C17orf74 Gene

Aliases for C17orf74 Gene

  • Chromosome 17 Open Reading Frame 74 2 3 5

External Ids for C17orf74 Gene

Previous GeneCards Identifiers for C17orf74 Gene

  • GC17P007270
  • GC17P007331
  • GC17P007222
  • GC17P007333
  • GC17P007336
  • GC17P007340
  • GC17P007450
  • GC17P007468

Summaries for C17orf74 Gene

GeneCards Summary for C17orf74 Gene

C17orf74 (Chromosome 17 Open Reading Frame 74) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf74 Gene

Genomics for C17orf74 Gene

Regulatory Elements for C17orf74 Gene

Enhancers for C17orf74 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C17orf74 on UCSC Golden Path with GeneCards custom track

Genomic Location for C17orf74 Gene

Chromosome:
17
Start:
7,424,881 bp from pter
End:
7,427,568 bp from pter
Size:
2,688 bases
Orientation:
Plus strand

Genomic View for C17orf74 Gene

Genes around C17orf74 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C17orf74 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C17orf74 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf74 Gene

Proteins for C17orf74 Gene

  • Protein details for C17orf74 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q0P670-CQ074_HUMAN
    Recommended name:
    Uncharacterized protein C17orf74
    Protein Accession:
    Q0P670

    Protein attributes for C17orf74 Gene

    Size:
    501 amino acids
    Molecular mass:
    57131 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C17orf74 Gene

Proteomics data for C17orf74 Gene at MOPED

Post-translational modifications for C17orf74 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf74 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C17orf74 Gene

Domains & Families for C17orf74 Gene

Protein Domains for C17orf74 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf74: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf74 Gene

Function for C17orf74 Gene

genes like me logo Genes that share phenotypes with C17orf74: view

Animal Model Products

CRISPR Products

miRNA for C17orf74 Gene

miRTarBase miRNAs that target C17orf74

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf74 Gene

Localization for C17orf74 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C17orf74 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C17orf74 Gene COMPARTMENTS Subcellular localization image for C17orf74 gene
Compartment Confidence
cytosol 1
golgi apparatus 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for C17orf74 Gene

Pathways & Interactions for C17orf74 Gene

SuperPathways for C17orf74 Gene

No Data Available

Interacting Proteins for C17orf74 Gene

Gene Ontology (GO) - Biological Process for C17orf74 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C17orf74 Gene

Drugs & Compounds for C17orf74 Gene

No Compound Related Data Available

Transcripts for C17orf74 Gene

mRNA/cDNA for C17orf74 Gene

Unigene Clusters for C17orf74 Gene

Chromosome 17 open reading frame 74:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf74 Gene

No ASD Table

Relevant External Links for C17orf74 Gene

GeneLoc Exon Structure for
C17orf74
ECgene alternative splicing isoforms for
C17orf74

Expression for C17orf74 Gene

mRNA expression in normal human tissues for C17orf74 Gene

mRNA differential expression in normal tissues according to GTEx for C17orf74 Gene

This gene is overexpressed in Testis (x52.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C17orf74 Gene



SOURCE GeneReport for Unigene cluster for C17orf74 Gene Hs.380704

genes like me logo Genes that share expression patterns with C17orf74: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C17orf74 Gene

Orthologs for C17orf74 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C17orf74 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia C5H17orf74 35
  • 76.42 (n)
  • 66.67 (a)
C17orf74 36
  • 63 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4933402P03Rik 35
  • 72.79 (n)
  • 62.02 (a)
4933402P03Rik 16
4933402P03Rik 36
  • 62 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf74 35
  • 97.92 (n)
  • 97.04 (a)
C17orf74 36
  • 94 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC497938 35
  • 72.85 (n)
  • 61.29 (a)
Species with no ortholog for C17orf74:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf74 Gene

ENSEMBL:
Gene Tree for C17orf74 (if available)
TreeFam:
Gene Tree for C17orf74 (if available)

Paralogs for C17orf74 Gene

No data available for Paralogs for C17orf74 Gene

Variants for C17orf74 Gene

Sequence variations from dbSNP and Humsavar for C17orf74 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs13290 - 7,426,313(-) GCAGG(A/C/G/T)GAAAG intron-variant, reference, missense
VAR_032146 -
rs3744547 -- 7,424,039(-) AGAGT(A/G)GATTC upstream-variant-2KB
rs3744548 -- 7,423,915(-) GGAAG(A/G)TGAAG upstream-variant-2KB
rs6503020 -- 7,425,460(+) GGACC(A/G)GGCTC upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for C17orf74 Gene

Variant ID Type Subtype PubMed ID
esv2422288 CNV Deletion 17116639
nsv457659 CNV Loss 19166990
nsv907644 CNV Loss 21882294
nsv523672 CNV Loss 19592680
nsv470575 CNV Loss 18288195
dgv3054n71 CNV Loss 21882294
nsv526176 CNV Gain 19592680

Variation tolerance for C17orf74 Gene

Residual Variation Intolerance Score: 85.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.71; 73.16% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C17orf74 Gene

Disorders for C17orf74 Gene

Relevant External Links for C17orf74

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C17orf74

No disorders were found for C17orf74 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf74 Gene

Publications for C17orf74 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 67

Products for C17orf74 Gene

Sources for C17orf74 Gene

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