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Aliases for C17orf74 Gene

Aliases for C17orf74 Gene

  • Chromosome 17 Open Reading Frame 74 2 3

External Ids for C17orf74 Gene

Previous GeneCards Identifiers for C17orf74 Gene

  • GC17P007270
  • GC17P007331
  • GC17P007222
  • GC17P007333
  • GC17P007336
  • GC17P007340

Summaries for C17orf74 Gene

GeneCards Summary for C17orf74 Gene

C17orf74 (Chromosome 17 Open Reading Frame 74) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf74 Gene

Genomics for C17orf74 Gene

Regulatory Elements for C17orf74 Gene

Genomic Location for C17orf74 Gene

7,425,615 bp from pter
7,427,568 bp from pter
1,954 bases
Plus strand

Genomic View for C17orf74 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C17orf74 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf74 Gene

Proteins for C17orf74 Gene

  • Protein details for C17orf74 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C17orf74
    Protein Accession:
    Secondary Accessions:

    Protein attributes for C17orf74 Gene

    501 amino acids
    Molecular mass:
    57131 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C17orf74 Gene

Proteomics data for C17orf74 Gene at MOPED

Post-translational modifications for C17orf74 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf74 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for C17orf74 Gene

Domains for C17orf74 Gene

Protein Domains for C17orf74 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf74: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf74 Gene

Function for C17orf74 Gene

Phenotypes for C17orf74 Gene

GenomeRNAi human phenotypes for C17orf74:
genes like me logo Genes that share phenotypes with C17orf74: view

Animal Model Products

CRISPR Products

miRNA for C17orf74 Gene

miRTarBase miRNAs that target C17orf74

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C17orf74

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf74 Gene

Localization for C17orf74 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C17orf74 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for C17orf74 Gene COMPARTMENTS Subcellular localization image for C17orf74 gene
Compartment Confidence
cytosol 1
golgi apparatus 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for C17orf74 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C17orf74: view

Pathways for C17orf74 Gene

SuperPathways for C17orf74 Gene

No Data Available

Interacting Proteins for C17orf74 Gene

Gene Ontology (GO) - Biological Process for C17orf74 Gene


No data available for Pathways by source for C17orf74 Gene

Transcripts for C17orf74 Gene

mRNA/cDNA for C17orf74 Gene

Unigene Clusters for C17orf74 Gene

Chromosome 17 open reading frame 74:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C17orf74

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf74 Gene

No ASD Table

Relevant External Links for C17orf74 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C17orf74 Gene

mRNA expression in normal human tissues for C17orf74 Gene

mRNA differential expression in normal tissues according to GTEx for C17orf74 Gene

This gene is overexpressed in Testis (52.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C17orf74 Gene

SOURCE GeneReport for Unigene cluster for C17orf74 Gene Hs.380704

genes like me logo Genes that share expressions with C17orf74: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for C17orf74 Gene

Orthologs for C17orf74 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C17orf74 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia C5H17orf74 35
  • 76.42 (n)
  • 66.67 (a)
C17orf74 36
  • 63 (a)
(Mus musculus)
Mammalia 4933402P03Rik 35
  • 72.79 (n)
  • 62.02 (a)
4933402P03Rik 16
4933402P03Rik 36
  • 62 (a)
(Pan troglodytes)
Mammalia C17H17orf74 35
  • 97.92 (n)
  • 97.04 (a)
C17orf74 36
  • 94 (a)
(Rattus norvegicus)
Mammalia LOC497938 35
  • 72.85 (n)
  • 61.29 (a)
Species with no ortholog for C17orf74:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf74 Gene

Gene Tree for C17orf74 (if available)
Gene Tree for C17orf74 (if available)

Paralogs for C17orf74 Gene

No data available for Paralogs for C17orf74 Gene

Variants for C17orf74 Gene

Sequence variations from dbSNP and Humsavar for C17orf74 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs561423308 -- 7,426,025(+) GACAA(C/G)ATGAT missense, reference, utr-variant-5-prime
rs560059533 -- 7,426,506(+) ACACC(A/G)AGTGC missense, reference
rs557639101 -- 7,424,957(+) GGTGG(A/G)TTGGT upstream-variant-2KB
rs557559174 -- 7,425,572(+) GTGAC(C/T)TGGCT upstream-variant-2KB
rs557145881 -- 7,424,452(+) AGTAG(A/C)GGTTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C17orf74 Gene

Variant ID Type Subtype PubMed ID
esv2422288 CNV Deletion 17116639
nsv457659 CNV Loss 19166990
nsv907644 CNV Loss 21882294
nsv523672 CNV Loss 19592680
nsv470575 CNV Loss 18288195
dgv3054n71 CNV Loss 21882294
nsv526176 CNV Gain 19592680

Relevant External Links for C17orf74 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf74 Gene

Disorders for C17orf74 Gene

No disorders were found for C17orf74 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for C17orf74 Gene

Publications for C17orf74 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4

Products for C17orf74 Gene

Sources for C17orf74 Gene

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