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Aliases for C17orf64 Gene

Aliases for C17orf64 Gene

  • Chromosome 17 Open Reading Frame 64 2 3 5

External Ids for C17orf64 Gene

Previous GeneCards Identifiers for C17orf64 Gene

  • GC17P055855
  • GC17P058469
  • GC17P053870

Summaries for C17orf64 Gene

GeneCards Summary for C17orf64 Gene

C17orf64 (Chromosome 17 Open Reading Frame 64) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf64 Gene

Genomics for C17orf64 Gene

Regulatory Elements for C17orf64 Gene

Enhancers for C17orf64 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17G060356 1.5 Ensembl ENCODE dbSUPER 12.2 -36.0 -35960 0.9 HDGF PKNOX1 FOXA2 ARID4B PBX2 RCOR2 ETV4 HNF4A ZZZ3 CTCF C17orf64 USP32 HEATR6 GC17M060371 ENSG00000271626
GH17G060357 1.4 Ensembl ENCODE dbSUPER 12.2 -35.0 -34959 1.1 ZEB1 ZNF121 ZNF366 FOS ETV6 BCLAF1 CEBPB ZEB2 PRDM6 CEBPA C17orf64 USP32 HEATR6 GC17M060371 ENSG00000271626
GH17G060435 1.3 Ensembl ENCODE 11 +43.7 43674 1.1 HDGF PKNOX1 WRNIP1 SIN3A ARID4B ZNF2 ZBTB7B SLC30A9 GLIS2 ZNF143 C17orf64 HEATR6 CA4 RPL12P38 GC17M060489
GH17G060358 0.9 dbSUPER 12.2 -33.5 -33537 1.3 HDGF FOXA2 CBX3 ARNT NFRKB NFXL1 ZBTB40 CHAMP1 ZNF766 GATA2 C17orf64 USP32 HEATR6 GC17M060371 ENSG00000271626
GH17G060420 0.9 ENCODE 11.8 +29.1 29106 1.4 PKNOX1 FOXA2 ARID4B SIN3A NFXL1 ZNF48 RAD21 ZNF143 ZNF207 ETV6 C17orf64 LOC105371850 USP32
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C17orf64 on UCSC Golden Path with GeneCards custom track

Genomic Location for C17orf64 Gene

60,392,429 bp from pter
60,431,426 bp from pter
38,998 bases
Plus strand

Genomic View for C17orf64 Gene

Genes around C17orf64 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C17orf64 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C17orf64 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf64 Gene

Proteins for C17orf64 Gene

  • Protein details for C17orf64 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C17orf64
    Protein Accession:
    Secondary Accessions:
    • Q8IY87

    Protein attributes for C17orf64 Gene

    236 amino acids
    Molecular mass:
    27182 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH36356.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAH48806.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for C17orf64 Gene

Post-translational modifications for C17orf64 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf64 Gene

No data available for DME Specific Peptides for C17orf64 Gene

Domains & Families for C17orf64 Gene

Protein Domains for C17orf64 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf64: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf64 Gene

Function for C17orf64 Gene

genes like me logo Genes that share phenotypes with C17orf64: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf64 Gene

Localization for C17orf64 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C17orf64 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C17orf64 Gene

Pathways & Interactions for C17orf64 Gene

SuperPathways for C17orf64 Gene

No Data Available

Interacting Proteins for C17orf64 Gene

Gene Ontology (GO) - Biological Process for C17orf64 Gene


No data available for Pathways by source and SIGNOR curated interactions for C17orf64 Gene

Drugs & Compounds for C17orf64 Gene

No Compound Related Data Available

Transcripts for C17orf64 Gene

mRNA/cDNA for C17orf64 Gene

Unigene Clusters for C17orf64 Gene

Chromosome 17 open reading frame 64:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf64 Gene

No ASD Table

Relevant External Links for C17orf64 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C17orf64 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C17orf64 Gene

mRNA differential expression in normal tissues according to GTEx for C17orf64 Gene

This gene is overexpressed in Testis (x51.3).

Protein differential expression in normal tissues from HIPED for C17orf64 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for C17orf64 Gene

Protein tissue co-expression partners for C17orf64 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C17orf64 Gene:


SOURCE GeneReport for Unigene cluster for C17orf64 Gene:

genes like me logo Genes that share expression patterns with C17orf64: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C17orf64 Gene

Orthologs for C17orf64 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C17orf64 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C17H17orf64 34
  • 99.01 (n)
C17orf64 35
  • 98 (a)
(Bos Taurus)
Mammalia C19H17orf64 34
  • 82.04 (n)
C17orf64 35
  • 73 (a)
(Canis familiaris)
Mammalia C9H17orf64 34
  • 81.77 (n)
C17orf64 35
  • 76 (a)
(Rattus norvegicus)
Mammalia RGD1310166 34
  • 79.4 (n)
(Mus musculus)
Mammalia 1700125H20Rik 34 16 35
  • 78.77 (n)
(Monodelphis domestica)
Mammalia C17orf64 35
  • 67 (a)
(Ornithorhynchus anatinus)
Mammalia C17orf64 35
  • 29 (a)
(Gallus gallus)
Aves C17orf64 35
  • 61 (a)
(Anolis carolinensis)
Reptilia C17orf64 35
  • 52 (a)
Species where no ortholog for C17orf64 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf64 Gene

Gene Tree for C17orf64 (if available)
Gene Tree for C17orf64 (if available)

Paralogs for C17orf64 Gene

(1) SIMAP similar genes for C17orf64 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with C17orf64: view

No data available for Paralogs for C17orf64 Gene

Variants for C17orf64 Gene

Sequence variations from dbSNP and Humsavar for C17orf64 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000013402 -- 60,420,196(+) GCCAT(G/T)TTGGC intron-variant, upstream-variant-2KB
rs1000358498 -- 60,420,088(+) ATTTT(-/ATTTTA)TTTGT intron-variant, upstream-variant-2KB
rs1000468956 -- 60,426,367(+) CCCAT(A/G)CCTAC intron-variant
rs1000585884 -- 60,422,137(+) CAAAT(C/T)AGAAA intron-variant, upstream-variant-2KB
rs1000691460 -- 60,421,726(+) CTCAG(-/ACTACA)CCCGG intron-variant, upstream-variant-2KB, cds-indel

Structural Variations from Database of Genomic Variants (DGV) for C17orf64 Gene

Variant ID Type Subtype PubMed ID
dgv3273n100 CNV gain 25217958
nsv519929 CNV loss 19592680
nsv521420 CNV loss 19592680

Variation tolerance for C17orf64 Gene

Residual Variation Intolerance Score: 45.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.29; 62.78% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C17orf64 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf64 Gene

Disorders for C17orf64 Gene

Relevant External Links for C17orf64

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C17orf64 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf64 Gene

Publications for C17orf64 Gene

  1. The Chromatin Remodelling Protein CHD1 Contains a Previously Unrecognised C-Terminal Helical Domain. (PMID: 27591891) Mohanty B. … Ryan D.P. (J. Mol. Biol. 2016) 2 3 64
  2. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C17orf64 Gene

Sources for C17orf64 Gene

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