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Aliases for C17orf62 Gene

Aliases for C17orf62 Gene

  • Chromosome 17 Open Reading Frame 62 2 3 5

External Ids for C17orf62 Gene

Previous GeneCards Identifiers for C17orf62 Gene

  • GC17M077994
  • GC17M080400
  • GC17M075798

Summaries for C17orf62 Gene

GeneCards Summary for C17orf62 Gene

C17orf62 (Chromosome 17 Open Reading Frame 62) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf62 Gene

Genomics for C17orf62 Gene

Regulatory Elements for C17orf62 Gene

Enhancers for C17orf62 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around C17orf62 on UCSC Golden Path with GeneCards custom track

Promoters for C17orf62 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for C17orf62 Gene

Chromosome:
17
Start:
82,442,586 bp from pter
End:
82,450,831 bp from pter
Size:
8,246 bases
Orientation:
Minus strand

Genomic View for C17orf62 Gene

Genes around C17orf62 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C17orf62 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C17orf62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf62 Gene

Proteins for C17orf62 Gene

  • Protein details for C17orf62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BQA9-CQ062_HUMAN
    Recommended name:
    Uncharacterized protein C17orf62
    Protein Accession:
    Q9BQA9
    Secondary Accessions:
    • E1B6X3
    • Q96NR1

    Protein attributes for C17orf62 Gene

    Size:
    187 amino acids
    Molecular mass:
    20774 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB70818.1; Type=Miscellaneous discrepancy; Note=Wrong choice of frame.; Evidence={ECO:0000305};

    Alternative splice isoforms for C17orf62 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C17orf62 Gene

Post-translational modifications for C17orf62 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C17orf62 Gene

Domains & Families for C17orf62 Gene

Protein Domains for C17orf62 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C17orf62 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf62: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C17orf62 Gene

Function for C17orf62 Gene

Gene Ontology (GO) - Molecular Function for C17orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 20195357
genes like me logo Genes that share ontologies with C17orf62: view
genes like me logo Genes that share phenotypes with C17orf62: view

Animal Models for C17orf62 Gene

MGI Knock Outs for C17orf62:

Animal Model Products

CRISPR Products

miRNA for C17orf62 Gene

miRTarBase miRNAs that target C17orf62

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for C17orf62 Gene

Localization for C17orf62 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C17orf62 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C17orf62 Gene COMPARTMENTS Subcellular localization image for C17orf62 gene
Compartment Confidence
mitochondrion 3
plasma membrane 3
cytosol 1
endoplasmic reticulum 1
golgi apparatus 1
nucleus 1

Gene Ontology (GO) - Cellular Components for C17orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C17orf62: view

Pathways & Interactions for C17orf62 Gene

SuperPathways for C17orf62 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C17orf62 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C17orf62 Gene

Drugs & Compounds for C17orf62 Gene

No Compound Related Data Available

Transcripts for C17orf62 Gene

Unigene Clusters for C17orf62 Gene

Chromosome 17 open reading frame 62:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf62 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b · 9c · 9d ^ 10 ^
SP1: - - - - - - - - - - - - -
SP2: - - - - - - - - - - - - - - -
SP3: - - - - - - - -
SP4: - - - - - - - - - - - - - - - -
SP5: - - - - - - - - - - - - - - - -
SP6: - - - - - - - - - - - - -
SP7: - - - - - - -
SP8: - - - - - - - - -
SP9: - - - - - - - - - - -
SP10: - - - - - -
SP11: - - - - -
SP12: - - - - - - - - - - - - - - - - - -
SP13: - - - - - - - - - - - -
SP14: - - - - -
SP15: - - - - - - - - - -
SP16: - - - - - - - - - - - - - - - - -
SP17: - - - - - - - - - - - - -
SP18: - - -
SP19: -
SP20: - - - - - - - - - - - - - -
SP21: - - - - - - -
SP22:
SP23: -

ExUns: 11a · 11b · 11c · 11d · 11e · 11f
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:

Relevant External Links for C17orf62 Gene

GeneLoc Exon Structure for
C17orf62
ECgene alternative splicing isoforms for
C17orf62

Expression for C17orf62 Gene

mRNA expression in normal human tissues for C17orf62 Gene

mRNA differential expression in normal tissues according to GTEx for C17orf62 Gene

This gene is overexpressed in Whole Blood (x12.5).

Protein differential expression in normal tissues from HIPED for C17orf62 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (9.9) and Blymphocyte (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C17orf62 Gene



Protein tissue co-expression partners for C17orf62 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C17orf62 Gene:

C17orf62

SOURCE GeneReport for Unigene cluster for C17orf62 Gene:

Hs.163113
genes like me logo Genes that share expression patterns with C17orf62: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C17orf62 Gene

Orthologs for C17orf62 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C17orf62 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C19H17orf62 34
  • 87.7 (n)
  • 90.91 (a)
C17orf62 35
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC608239 34
  • 87.52 (n)
  • 87.63 (a)
C17orf62 35
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia BC017643 34
  • 86.99 (n)
  • 88.77 (a)
BC017643 16
BC017643 35
  • 89 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf62 34
  • 100 (n)
  • 100 (a)
rat
(Rattus norvegicus)
Mammalia LOC619574 34
  • 86.45 (n)
  • 89.3 (a)
oppossum
(Monodelphis domestica)
Mammalia C17orf62 35
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C17orf62 35
  • 74 (a)
OneToOne
chicken
(Gallus gallus)
Aves C18H17ORF62 34
  • 71.09 (n)
  • 70.72 (a)
C17orf62 35
  • 68 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C17orf62 35
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c17orf62 34
  • 67.77 (n)
  • 68.13 (a)
zebrafish
(Danio rerio)
Actinopterygii zgc:91940 34
  • 62.04 (n)
  • 62.78 (a)
C12H17orf62 (1 of 2) 35
  • 54 (a)
OneToMany
C12H17orf62 (2 of 2) 35
  • 53 (a)
OneToMany
Species where no ortholog for C17orf62 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C17orf62 Gene

ENSEMBL:
Gene Tree for C17orf62 (if available)
TreeFam:
Gene Tree for C17orf62 (if available)

Paralogs for C17orf62 Gene

genes like me logo Genes that share paralogs with C17orf62: view

No data available for Paralogs for C17orf62 Gene

Variants for C17orf62 Gene

Sequence variations from dbSNP and Humsavar for C17orf62 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs2291394 -- 82,446,018(-) CCCAG(C/T)GGCCA intron-variant
rs2306758 -- 82,444,070(-) TGCCT(C/T)GAGAG nc-transcript-variant, reference, synonymous-codon
rs3751913 -- 82,447,676(-) GCACC(A/G)GGGAG intron-variant
rs4789688 -- 82,450,074(+) TCACG(G/T)AGTTC intron-variant, nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs7210573 -- 82,451,911(+) gcggg(C/T)gctca upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C17orf62 Gene

Variant ID Type Subtype PubMed ID
esv21913 CNV gain+loss 19812545
esv2716503 CNV deletion 23290073
esv2762577 CNV gain+loss 21179565
esv3641424 CNV gain 21293372
esv3641425 CNV loss 21293372
nsv1062980 CNV gain 25217958
nsv1067160 CNV loss 25217958
nsv1067194 CNV gain 25217958
nsv1160502 CNV deletion 26073780
nsv428351 CNV gain 18775914
nsv469561 CNV loss 16826518
nsv833574 CNV gain 17160897

Variation tolerance for C17orf62 Gene

Residual Variation Intolerance Score: 87.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.81; 47.60% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C17orf62 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C17orf62

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf62 Gene

Disorders for C17orf62 Gene

Relevant External Links for C17orf62

Genetic Association Database (GAD)
C17orf62
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C17orf62

No disorders were found for C17orf62 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf62 Gene

Publications for C17orf62 Gene

  1. [Study on the mechanism of C17orf62 induced cell death]. (PMID: 21503106) Deng X. … Shi T.P. (Beijing Da Xue Xue Bao 2011) 2 3 65
  2. A genome-wide association study identifies protein quantitative trait loci (pQTLs). (PMID: 18464913) Melzer D. … Ferrucci L. (PLoS Genet. 2008) 3 46 65
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 65

Products for C17orf62 Gene

Sources for C17orf62 Gene

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