Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C17orf59 Gene

Aliases for C17orf59 Gene

  • Chromosome 17 Open Reading Frame 59 2 3
  • Uncharacterized Protein C17orf59 3
  • PRO2472 3

External Ids for C17orf59 Gene

Previous GeneCards Identifiers for C17orf59 Gene

  • GC17M008033
  • GC17M008038
  • GC17M008091
  • GC17M007988

Summaries for C17orf59 Gene

GeneCards Summary for C17orf59 Gene

C17orf59 (Chromosome 17 Open Reading Frame 59) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf59 Gene

Genomics for C17orf59 Gene

Regulatory Elements for C17orf59 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C17orf59 Gene

Start:
8,188,333 bp from pter
End:
8,190,907 bp from pter
Size:
2,575 bases
Orientation:
Minus strand

Genomic View for C17orf59 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C17orf59 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf59 Gene

Proteins for C17orf59 Gene

  • Protein details for C17orf59 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96GS4-CQ059_HUMAN
    Recommended name:
    Uncharacterized protein C17orf59
    Protein Accession:
    Q96GS4
    Secondary Accessions:
    • Q53HS4
    • Q9NXW8

    Protein attributes for C17orf59 Gene

    Size:
    357 amino acids
    Molecular mass:
    37226 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH09261.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH18880.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH70272.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAA90889.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAD96226.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for C17orf59 Gene

Proteomics data for C17orf59 Gene at MOPED

Post-translational modifications for C17orf59 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf59 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C17orf59 Gene

Domains for C17orf59 Gene

Protein Domains for C17orf59 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf59: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf59 Gene

Function for C17orf59 Gene

Gene Ontology (GO) - Molecular Function for C17orf59 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C17orf59: view

Animal Model Products

CRISPR Products

miRNA for C17orf59 Gene

miRTarBase miRNAs that target C17orf59

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C17orf59

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C17orf59 Gene

Localization for C17orf59 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C17orf59 Gene COMPARTMENTS Subcellular localization image for C17orf59 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 1
lysosome 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C17orf59 Gene

Pathways for C17orf59 Gene

SuperPathways for C17orf59 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C17orf59 Gene

None

No data available for Pathways by source for C17orf59 Gene

Transcripts for C17orf59 Gene

mRNA/cDNA for C17orf59 Gene

(58) Selected AceView cDNA sequences:
(5) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C17orf59 Gene

Chromosome 17 open reading frame 59:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C17orf59

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf59 Gene

No ASD Table

Relevant External Links for C17orf59 Gene

GeneLoc Exon Structure for
C17orf59
ECgene alternative splicing isoforms for
C17orf59

Expression for C17orf59 Gene

mRNA expression in normal human tissues for C17orf59 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for C17orf59 Gene

SOURCE GeneReport for Unigene cluster for C17orf59 Gene Hs.129563

genes like me logo Genes that share expressions with C17orf59: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C17orf59 Gene

Orthologs for C17orf59 Gene

This gene was present in the common ancestor of animals.

Orthologs for C17orf59 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf59 35
  • 99.35 (n)
  • 98.88 (a)
C17orf59 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C19H17orf59 35
  • 84.28 (n)
  • 81.53 (a)
C19H17orf59 36
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C17orf59 36
  • 77 (a)
OneToOne
C5H17orf59 35
  • 81.3 (n)
  • 75.29 (a)
mouse
(Mus musculus)
Mammalia 2310047M10Rik 35
  • 80.28 (n)
  • 74.37 (a)
2310047M10Rik 16
2310047M10Rik 36
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C17orf59 36
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C17orf59 36
  • 89 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC497934 35
  • 79.72 (n)
  • 73.24 (a)
chicken
(Gallus gallus)
Aves C17orf59 36
  • 55 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C17orf59 36
  • 62 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.11680 35
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.9242 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.6370 35
zebrafish
(Danio rerio)
Actinopterygii C8H17orf59 36
  • 30 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG17180 36
  • 23 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y37E11B.3 36
  • 31 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10551 36
  • 25 (a)
OneToOne
Species with no ortholog for C17orf59:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for C17orf59 Gene

ENSEMBL:
Gene Tree for C17orf59 (if available)
TreeFam:
Gene Tree for C17orf59 (if available)

Paralogs for C17orf59 Gene

No data available for Paralogs for C17orf59 Gene

Variants for C17orf59 Gene

Sequence variations from dbSNP and Humsavar for C17orf59 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs8531 -- 8,189,376(+) TCGAT(G/T)GGGGG reference, synonymous-codon
rs2233758 -- 8,188,120(+) GTTAC(C/T)GGATC downstream-variant-500B
rs2233759 -- 8,188,133(+) TGGGC(C/T)CCTGT downstream-variant-500B
rs2233760 -- 8,188,209(+) TCCCC(A/T)CGGAG downstream-variant-500B
rs2233761 -- 8,188,210(+) CCCCA(C/T)GGAGC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for C17orf59 Gene

Variant ID Type Subtype PubMed ID
nsv907658 CNV Loss 21882294
nsv527475 CNV Loss 19592680
nsv833353 CNV Loss 17160897

Relevant External Links for C17orf59 Gene

HapMap Linkage Disequilibrium report
C17orf59

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf59 Gene

Disorders for C17orf59 Gene

No disorders were found for C17orf59 Gene.

No data available for UniProtKB/Swiss-Prot for C17orf59 Gene

Publications for C17orf59 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Construction and characterization of a normalized yeast two-hybrid library derived from a human protein-coding clone collection. (PMID: 18330356) DeGrado-Warren J. … Frech G.C. (BioTechniques 2008) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for C17orf59 Gene

Sources for C17orf59 Gene

Back to Top

Content