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Aliases for C17orf58 Gene

Aliases for C17orf58 Gene

  • Chromosome 17 Open Reading Frame 58 2 3

External Ids for C17orf58 Gene

Previous GeneCards Identifiers for C17orf58 Gene

  • GC17M063418
  • GC17M065987
  • GC17M061371

Summaries for C17orf58 Gene

GeneCards Summary for C17orf58 Gene

C17orf58 (Chromosome 17 Open Reading Frame 58) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf58 Gene

Genomics for C17orf58 Gene

Regulatory Elements for C17orf58 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C17orf58 Gene

Start:
67,991,099 bp from pter
End:
67,993,649 bp from pter
Size:
2,551 bases
Orientation:
Minus strand

Genomic View for C17orf58 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C17orf58 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf58 Gene

Proteins for C17orf58 Gene

  • Protein details for C17orf58 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2M2W7-CQ058_HUMAN
    Recommended name:
    UPF0450 protein C17orf58
    Protein Accession:
    Q2M2W7
    Secondary Accessions:
    • A8MQV2

    Protein attributes for C17orf58 Gene

    Size:
    97 amino acids
    Molecular mass:
    11219 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C17orf58 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C17orf58 Gene

Proteomics data for C17orf58 Gene at MOPED

Post-translational modifications for C17orf58 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf58 Gene

No data available for DME Specific Peptides for C17orf58 Gene

Domains for C17orf58 Gene

Protein Domains for C17orf58 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C17orf58 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q2M2W7

UniProtKB/Swiss-Prot:

CQ058_HUMAN :
  • Q2M2W7
Family:
  • Belongs to the UPF0450 family.
genes like me logo Genes that share domains with C17orf58: view

No data available for Gene Families for C17orf58 Gene

Function for C17orf58 Gene

Animal Model Products

CRISPR Products

miRNA for C17orf58 Gene

miRTarBase miRNAs that target C17orf58

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C17orf58 Gene

Localization for C17orf58 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C17orf58 Gene COMPARTMENTS Subcellular localization image for C17orf58 gene
Compartment Confidence
cytosol 2
extracellular 2
nucleus 2
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C17orf58 Gene

Pathways for C17orf58 Gene

SuperPathways for C17orf58 Gene

No Data Available

Interacting Proteins for C17orf58 Gene

Gene Ontology (GO) - Biological Process for C17orf58 Gene

None

No data available for Pathways by source for C17orf58 Gene

Transcripts for C17orf58 Gene

mRNA/cDNA for C17orf58 Gene

Unigene Clusters for C17orf58 Gene

Chromosome 17 open reading frame 58:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C17orf58

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf58 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c
SP1: - -
SP2: -
SP3:

Relevant External Links for C17orf58 Gene

GeneLoc Exon Structure for
C17orf58
ECgene alternative splicing isoforms for
C17orf58

Expression for C17orf58 Gene

mRNA expression in normal human tissues for C17orf58 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C17orf58 Gene

SOURCE GeneReport for Unigene cluster for C17orf58 Gene Hs.90790

genes like me logo Genes that share expressions with C17orf58: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C17orf58 Gene

Orthologs for C17orf58 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C17orf58 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf58 35
  • 100 (n)
  • 100 (a)
C17ORF58 36
  • 48 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C19H17orf58 35
  • 88.32 (n)
  • 93.75 (a)
dog
(Canis familiaris)
Mammalia C17orf58 36
  • 92 (a)
OneToOne
C9H17orf58 35
  • 89 (n)
  • 91.75 (a)
mouse
(Mus musculus)
Mammalia 1810010H24Rik 35
  • 84.54 (n)
  • 88.66 (a)
1810010H24Rik 16
oppossum
(Monodelphis domestica)
Mammalia C17orf58 36
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C17orf58 36
  • 43 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1565033 35
  • 82.82 (n)
  • 85.57 (a)
chicken
(Gallus gallus)
Aves C17ORF58 35
  • 72.92 (n)
  • 73.96 (a)
C17orf58 36
  • 74 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C17orf58 36
  • 48 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.14404 35
Species with no ortholog for C17orf58:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf58 Gene

ENSEMBL:
Gene Tree for C17orf58 (if available)
TreeFam:
Gene Tree for C17orf58 (if available)

Paralogs for C17orf58 Gene

Pseudogenes.org Pseudogenes for C17orf58 Gene

genes like me logo Genes that share paralogs with C17orf58: view

No data available for Paralogs for C17orf58 Gene

Variants for C17orf58 Gene

Sequence variations from dbSNP and Humsavar for C17orf58 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs5821444 -- 67,991,394(-) AAGTA(-/TTA)AAGTT cds-indel
rs7502307 -- 67,993,845(+) TCAGG(C/G)CAggc upstream-variant-2KB
rs7502455 -- 67,993,686(+) gcgcg(C/T)cgcgg upstream-variant-2KB
rs9891146 - 67,991,933(+) ATGAA(C/T)TGCAC reference, missense, utr-variant-3-prime
rs11657797 -- 67,990,664(+) CGCTT(C/T)TGTTG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for C17orf58 Gene

Variant ID Type Subtype PubMed ID
nsv436233 CNV Deletion 17901297
esv2716136 CNV Deletion 23290073
esv22750 CNV Gain 19812545
nsv471405 CNV Duplication 19718026
esv26540 CNV Loss 19812545

Relevant External Links for C17orf58 Gene

HapMap Linkage Disequilibrium report
C17orf58

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf58 Gene

Disorders for C17orf58 Gene

No disorders were found for C17orf58 Gene.

No data available for UniProtKB/Swiss-Prot for C17orf58 Gene

Publications for C17orf58 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  4. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4

Products for C17orf58 Gene

Sources for C17orf58 Gene

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