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Aliases for C17orf51 Gene

Aliases for C17orf51 Gene

  • Chromosome 17 Open Reading Frame 51 2 3 5

External Ids for C17orf51 Gene

Previous GeneCards Identifiers for C17orf51 Gene

  • GC17M021377
  • GC17M020633
  • GC17M021428

Summaries for C17orf51 Gene

GeneCards Summary for C17orf51 Gene

C17orf51 (Chromosome 17 Open Reading Frame 51) is a Protein Coding gene.

Additional gene information for C17orf51 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf51 Gene

Genomics for C17orf51 Gene

Regulatory Elements for C17orf51 Gene

Enhancers for C17orf51 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H021549 1 ENCODE 17.4 +23.8 23756 3.2 ARID4B SIN3A ZNF2 ZNF121 GLIS2 FOS ATF7 SP3 YY2 KAT8 C17orf51 MEIS3P2 ENSG00000235530 ENSG00000266673 GC17M021537 PIR39297
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C17orf51 on UCSC Golden Path with GeneCards custom track

Promoters for C17orf51 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000092503 57 1199 RFX1 GLIS1 NRF1 HNF4A

Genomic Locations for C17orf51 Gene

Genomic Locations for C17orf51 Gene
134,619 bases
Minus strand

Genomic View for C17orf51 Gene

Genes around C17orf51 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C17orf51 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C17orf51 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf51 Gene

Proteins for C17orf51 Gene

  • Protein details for C17orf51 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C17orf51
    Protein Accession:
    Secondary Accessions:
    • B2RN29
    • B5MCL4

    Protein attributes for C17orf51 Gene

    221 amino acids
    Molecular mass:
    24325 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C17orf51 Gene

Post-translational modifications for C17orf51 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf51 Gene

No data available for DME Specific Peptides for C17orf51 Gene

Domains & Families for C17orf51 Gene

Gene Families for C17orf51 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C17orf51 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf51: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf51 Gene

Function for C17orf51 Gene

Phenotypes for C17orf51 Gene

genes like me logo Genes that share phenotypes with C17orf51: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf51 Gene

Localization for C17orf51 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C17orf51 gene
Compartment Confidence
nucleus 4
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (2)
  • Nucleoplasm (2)
  • Vesicles (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C17orf51 Gene

Pathways & Interactions for C17orf51 Gene

SuperPathways for C17orf51 Gene

No Data Available

Interacting Proteins for C17orf51 Gene

Gene Ontology (GO) - Biological Process for C17orf51 Gene


No data available for Pathways by source and SIGNOR curated interactions for C17orf51 Gene

Drugs & Compounds for C17orf51 Gene

No Compound Related Data Available

Transcripts for C17orf51 Gene

Unigene Clusters for C17orf51 Gene

Chromosome 17 open reading frame 51:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf51 Gene

No ASD Table

Relevant External Links for C17orf51 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C17orf51 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C17orf51 Gene

mRNA differential expression in normal tissues according to GTEx for C17orf51 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x4.8) and Brain - Cerebellum (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of C17orf51 Gene:


SOURCE GeneReport for Unigene cluster for C17orf51 Gene:


Evidence on tissue expression from TISSUES for C17orf51 Gene

  • Nervous system(3.9)
genes like me logo Genes that share expression patterns with C17orf51: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C17orf51 Gene

Orthologs for C17orf51 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C17orf51 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C17orf51 34
  • 100 (a)
C17H17orf51 33
  • 99.55 (n)
Species where no ortholog for C17orf51 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf51 Gene

Gene Tree for C17orf51 (if available)
Gene Tree for C17orf51 (if available)

Paralogs for C17orf51 Gene

(3) SIMAP similar genes for C17orf51 Gene using alignment to 2 proteins: Pseudogenes for C17orf51 Gene

genes like me logo Genes that share paralogs with C17orf51: view

No data available for Paralogs for C17orf51 Gene

Variants for C17orf51 Gene

Sequence variations from dbSNP and Humsavar for C17orf51 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000153452 -- 21,530,333(+) GGATA(C/G)ATAAG intron-variant, utr-variant-3-prime
rs1000296181 -- 21,527,357(+) GAGGC(A/G)AATCC intron-variant, downstream-variant-500B
rs1000349182 -- 21,527,025(+) CTCTA(C/T)AGTTA intron-variant
rs1000457201 -- 21,533,080(+) GCACT(C/G)TAGTG intron-variant, utr-variant-3-prime
rs1000806974 -- 21,533,314(+) GCGTT(C/T)CCCTC intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C17orf51 Gene

Variant ID Type Subtype PubMed ID
nsv978552 CNV duplication 23825009
nsv978397 CNV duplication 23825009
nsv9517 CNV loss 18304495
nsv833401 CNV gain 17160897
nsv817756 CNV gain 17921354
nsv574609 CNV loss 21841781
nsv574606 CNV loss 21841781
nsv574604 CNV gain 21841781
nsv517456 CNV gain+loss 19592680
nsv2009 CNV deletion 18451855
nsv1160464 CNV duplication 26073780
nsv1078306 OTHER inversion 25765185
nsv1059216 CNV gain 25217958
nsv1059146 CNV gain 25217958
esv3892984 CNV gain+loss 25118596
esv34477 CNV gain 17911159
esv32532 CNV loss 17666407
esv2763159 CNV gain 21179565
esv2758681 CNV gain+loss 17122850
esv2751620 CNV loss 17911159
esv2660756 CNV deletion 23128226
dgv898e212 CNV loss 25503493
dgv897e212 CNV gain 25503493
dgv5504n54 CNV gain 21841781
dgv5503n54 CNV gain 21841781
dgv363n27 CNV gain 19166990
dgv3127n100 CNV gain 25217958
dgv3126n100 CNV loss 25217958
dgv3125n100 CNV gain+loss 25217958
dgv3124n100 CNV gain 25217958
dgv3123n100 CNV gain 25217958

Variation tolerance for C17orf51 Gene

Gene Damage Index Score: 3.97; 59.92% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C17orf51 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf51 Gene

Disorders for C17orf51 Gene

Relevant External Links for C17orf51

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C17orf51 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf51 Gene

Publications for C17orf51 Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 3 4 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  4. Genome-wide association analysis identifies three psoriasis susceptibility loci. (PMID: 20953189) Stuart PE … Elder JT (Nature genetics 2010) 45 60
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for C17orf51 Gene

Sources for C17orf51 Gene

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