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Aliases for C17orf105 Gene

Aliases for C17orf105 Gene

  • Chromosome 17 Open Reading Frame 105 2 3 5

External Ids for C17orf105 Gene

Previous GeneCards Identifiers for C17orf105 Gene

  • GC17P039214
  • GC17P041857
  • GC17P037621

Summaries for C17orf105 Gene

GeneCards Summary for C17orf105 Gene

C17orf105 (Chromosome 17 Open Reading Frame 105) is a Protein Coding gene. An important paralog of this gene is LOC101929355.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf105 Gene

Genomics for C17orf105 Gene

Regulatory Elements for C17orf105 Gene

Enhancers for C17orf105 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F044024 0.3 FANTOM5 25.1 +246.1 246074 0.4 HDAC1 ARID4B SIN3A DMAP1 ZNF2 RAD21 RARA ZNF143 CREM THAP11 C17orf105 LSM12 NAGS CD300LG ENSG00000221044 PYY TMEM101
GH17F043926 1.1 FANTOM5 ENCODE 23.8 +149.8 149817 2.8 SOX13 GATAD2A SOX5 TFAP4 NRF1 FEZF1 HMG20A OSR2 ZNF121 TCF7 LSM12 C17orf105 MPP2 NAGS PYY ENSG00000221044 CD300LG LOC102724183 LINC01976
GH17F043822 0.2 ENCODE 11.3 +45.1 45117 1.4 ZNF362 ZNF384 ZIC2 DUSP3 C17orf105 SOST MEOX1 MPP3 RNU6-1137P PIR46069
GH17F043803 0.2 ENCODE 11.2 +25.6 25573 1.2 TEAD4 MPP3 DUSP3 C17orf105 SOST MEOX1 ENSG00000221044 PIR46069
GH17F043846 1.1 Ensembl ENCODE 10.9 +68.4 68407 1.2 ARID4B ZNF48 ZNF2 RAD21 SCRT2 ZNF143 EGR2 THAP11 ZNF263 ZNF654 C17orf105 DUSP3 SOST ENSG00000221044 CD300LG GC17P043880
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C17orf105 on UCSC Golden Path with GeneCards custom track

Promoters for C17orf105 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001346957 309 1801 HDGF PKNOX1 MLX ARID4B SIN3A FEZF1 DMAP1 YY1 SLC30A9 ZNF143

Genomic Location for C17orf105 Gene

43,778,391 bp from pter
43,787,612 bp from pter
9,222 bases
Plus strand

Genomic View for C17orf105 Gene

Genes around C17orf105 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C17orf105 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C17orf105 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf105 Gene

Proteins for C17orf105 Gene

  • Protein details for C17orf105 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C17orf105
    Protein Accession:

    Protein attributes for C17orf105 Gene

    164 amino acids
    Molecular mass:
    19546 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C17orf105 Gene

Post-translational modifications for C17orf105 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf105 Gene

No data available for DME Specific Peptides for C17orf105 Gene

Domains & Families for C17orf105 Gene

Protein Domains for C17orf105 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf105: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf105 Gene

Function for C17orf105 Gene

Animal Model Products

miRNA for C17orf105 Gene

miRTarBase miRNAs that target C17orf105

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf105 Gene

Localization for C17orf105 Gene

Subcellular locations from

Jensen Localization Image for C17orf105 Gene COMPARTMENTS Subcellular localization image for C17orf105 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C17orf105 Gene

Pathways & Interactions for C17orf105 Gene

SuperPathways for C17orf105 Gene

No Data Available

Interacting Proteins for C17orf105 Gene

Selected Interacting proteins: B2RV13-CQ105_HUMAN for C17orf105 Gene via IID

Gene Ontology (GO) - Biological Process for C17orf105 Gene


No data available for Pathways by source and SIGNOR curated interactions for C17orf105 Gene

Transcripts for C17orf105 Gene

Unigene Clusters for C17orf105 Gene

Chromosome 17 open reading frame 105:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf105 Gene

No ASD Table

Relevant External Links for C17orf105 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C17orf105 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C17orf105 Gene

mRNA differential expression in normal tissues according to GTEx for C17orf105 Gene

This gene is overexpressed in Testis (x48.0).

Protein differential expression in normal tissues from HIPED for C17orf105 Gene

This gene is overexpressed in Pancreas (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C17orf105 Gene

Protein tissue co-expression partners for C17orf105 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C17orf105 Gene:


SOURCE GeneReport for Unigene cluster for C17orf105 Gene:

genes like me logo Genes that share expression patterns with C17orf105: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C17orf105 Gene

Orthologs for C17orf105 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C17orf105 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C17H17orf105 34
  • 99.19 (n)
C17orf105 35
  • 99 (a)
(Canis familiaris)
Mammalia C9H17orf105 34
  • 91.67 (n)
C17orf105 35
  • 90 (a)
(Bos Taurus)
Mammalia C19H17orf105 34
  • 90.45 (n)
C17orf105 35
  • 90 (a)
(Mus musculus)
Mammalia 1700006E09Rik 34 16 35
  • 87.8 (n)
(Rattus norvegicus)
Mammalia RGD1565533 34
  • 86.59 (n)
(Monodelphis domestica)
Mammalia C17orf105 35
  • 48 (a)
(Ornithorhynchus anatinus)
Mammalia C17orf105 35
  • 29 (a)
(Gallus gallus)
Aves C17orf105 35
  • 35 (a)
(Anolis carolinensis)
Reptilia C17orf105 35
  • 40 (a)
(Danio rerio)
Actinopterygii C25H17orf105 (1 of 2) 35
  • 23 (a)
C9H17orf105 (2 of 2) 35
  • 22 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 27 (a)
Species where no ortholog for C17orf105 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C17orf105 Gene

Gene Tree for C17orf105 (if available)
Gene Tree for C17orf105 (if available)

Paralogs for C17orf105 Gene

Paralogs for C17orf105 Gene

genes like me logo Genes that share paralogs with C17orf105: view

Variants for C17orf105 Gene

Sequence variations from dbSNP and Humsavar for C17orf105 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs111474694 -- 43,781,443(+) CTCCC(A/G)CCTCA intron-variant
rs111671689 -- 43,783,888(+) AAAAT(A/G/T)AATAG nc-transcript-variant, reference, missense, stop-gained
rs111759049 -- 43,777,262(+) GCCAT(C/T)GTGCC intron-variant, upstream-variant-2KB
rs111911683 -- 43,781,354(+) CCCCC(-/T)GATAC intron-variant
rs112305901 -- 43,779,039(+) GCCCG(C/G)CGGGC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C17orf105 Gene

Variant ID Type Subtype PubMed ID
esv27934 CNV gain 19812545
esv3640637 CNV gain 21293372
nsv1060861 CNV gain 25217958
nsv1146669 OTHER inversion 26484159

Variation tolerance for C17orf105 Gene

Gene Damage Index Score: 0.89; 18.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C17orf105 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf105 Gene

Disorders for C17orf105 Gene

Relevant External Links for C17orf105

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C17orf105 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf105 Gene

Publications for C17orf105 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C17orf105 Gene

Sources for C17orf105 Gene

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