Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C17orf104 Gene

Aliases for C17orf104 Gene

  • Chromosome 17 Open Reading Frame 104 2 3

External Ids for C17orf104 Gene

Previous GeneCards Identifiers for C17orf104 Gene

  • GC17P040099
  • GC17P042733
  • GC17P038498

Summaries for C17orf104 Gene

GeneCards Summary for C17orf104 Gene

C17orf104 (Chromosome 17 Open Reading Frame 104) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf104 Gene

Genomics for C17orf104 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C17orf104 Gene

Chromosome:
17
Start:
44,656,394 bp from pter
End:
44,690,308 bp from pter
Size:
33,915 bases
Orientation:
Plus strand

Genomic View for C17orf104 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C17orf104 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf104 Gene

No data available for Regulatory Elements for C17orf104 Gene

Proteins for C17orf104 Gene

  • Protein details for C17orf104 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A2RUB1-CQ104_HUMAN
    Recommended name:
    Uncharacterized protein C17orf104
    Protein Accession:
    A2RUB1
    Secondary Accessions:
    • B4DXJ2
    • B5MD93
    • B9EGQ6
    • C4AM97
    • Q4G0Y1
    • Q8IVZ7
    • Q8NA45

    Protein attributes for C17orf104 Gene

    Size:
    952 amino acids
    Molecular mass:
    107559 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH35159.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI32823.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI36643.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for C17orf104 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C17orf104 Gene

Proteomics data for C17orf104 Gene at MOPED

Post-translational modifications for C17orf104 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf104 Gene

No data available for DME Specific Peptides for C17orf104 Gene

Domains & Families for C17orf104 Gene

Protein Domains for C17orf104 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf104: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf104 Gene

Function for C17orf104 Gene

Phenotypes for C17orf104 Gene

genes like me logo Genes that share phenotypes with C17orf104: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf104 Gene

Localization for C17orf104 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C17orf104 Gene

Pathways & Interactions for C17orf104 Gene

SuperPathways for C17orf104 Gene

No Data Available

Interacting Proteins for C17orf104 Gene

Gene Ontology (GO) - Biological Process for C17orf104 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C17orf104 Gene

Drugs & Compounds for C17orf104 Gene

No Compound Related Data Available

Transcripts for C17orf104 Gene

Unigene Clusters for C17orf104 Gene

Chromosome 17 open reading frame 104:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C17orf104

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf104 Gene

No ASD Table

Relevant External Links for C17orf104 Gene

GeneLoc Exon Structure for
C17orf104
ECgene alternative splicing isoforms for
C17orf104

Expression for C17orf104 Gene

mRNA expression in normal human tissues for C17orf104 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C17orf104 Gene

This gene is overexpressed in Testis (x24.0).

Protein differential expression in normal tissues from HIPED for C17orf104 Gene

This gene is overexpressed in Testis (32.0), Heart (13.4), Ovary (9.4), Prostate (7.4), and Peripheral blood mononuclear cells (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C17orf104 Gene



SOURCE GeneReport for Unigene cluster for C17orf104 Gene Hs.349758

genes like me logo Genes that share expression patterns with C17orf104: view

Protein tissue co-expression partners for C17orf104 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for C17orf104 Gene

Orthologs for C17orf104 Gene

This gene was present in the common ancestor of animals.

Orthologs for C17orf104 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C19H17orf104 35
  • 92.29 (n)
  • 90.85 (a)
C17orf104 36
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C9H17orf104 35
  • 92.69 (n)
  • 90.73 (a)
C17orf104 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm1564 35
  • 90.61 (n)
  • 88.64 (a)
Gm1564 16
Gm1564 36
  • 87 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf104 35
  • 99.54 (n)
  • 98.95 (a)
C17orf104 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1563746 35
  • 90.71 (n)
  • 88.85 (a)
oppossum
(Monodelphis domestica)
Mammalia C17orf104 36
  • 89 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C17orf104 36
  • 55 (a)
OneToOne
chicken
(Gallus gallus)
Aves C27H17ORF104 35
  • 67.91 (n)
  • 58.51 (a)
C17orf104 36
  • 57 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C17orf104 36
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100496184 35
  • 56.51 (n)
  • 42.05 (a)
zebrafish
(Danio rerio)
Actinopterygii C17orf104 36
  • 29 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y39A1A.9 36
  • 26 (a)
OneToOne
Species with no ortholog for C17orf104:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for C17orf104 Gene

ENSEMBL:
Gene Tree for C17orf104 (if available)
TreeFam:
Gene Tree for C17orf104 (if available)

Paralogs for C17orf104 Gene

No data available for Paralogs for C17orf104 Gene

Variants for C17orf104 Gene

Sequence variations from dbSNP and Humsavar for C17orf104 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs3897489 -- 44,676,505(-) TTCTA(C/T)GGTAA intron-variant
rs3897490 -- 44,676,022(-) TTACA(C/T)GGATT downstream-variant-500B, intron-variant
rs6416902 -- 44,674,239(+) ATATA(C/T)CAAGA utr-variant-3-prime, intron-variant
rs6503397 -- 44,670,299(+) AGGAA(A/C)GGGAA intron-variant
rs7218985 -- 44,674,275(+) TGTCA(A/G)ACTTT utr-variant-3-prime, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C17orf104 Gene

Variant ID Type Subtype PubMed ID
nsv908286 CNV Loss 21882294
nsv833456 CNV Gain+Loss 17160897
nsv908287 CNV Loss 21882294
nsv828020 CNV Gain 20364138
nsv112452 CNV Loss 16902084

Variation tolerance for C17orf104 Gene

Residual Variation Intolerance Score: 63.09% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.51; 77.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C17orf104 Gene

HapMap Linkage Disequilibrium report
C17orf104

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf104 Gene

Disorders for C17orf104 Gene

Relevant External Links for C17orf104

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C17orf104
genes like me logo Genes that share disorders with C17orf104: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf104 Gene

Publications for C17orf104 Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67
  5. Generation and analysis of 280,000 human expressed sequence tags. (PMID: 8889549) Hillier L.D. … Marra M. (Genome Res. 1996) 67

Products for C17orf104 Gene

Sources for C17orf104 Gene

Back to Top

Content