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Aliases for C17orf102 Gene

Aliases for C17orf102 Gene

  • Chromosome 17 Open Reading Frame 102 2 3 5

External Ids for C17orf102 Gene

Previous GeneCards Identifiers for C17orf102 Gene

  • GC17M029926
  • GC17M032901
  • GC17M029086

Summaries for C17orf102 Gene

GeneCards Summary for C17orf102 Gene

C17orf102 (Chromosome 17 Open Reading Frame 102) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C17orf102 Gene

Genomics for C17orf102 Gene

Regulatory Elements for C17orf102 Gene

Enhancers for C17orf102 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F034412 1.4 FANTOM5 Ensembl ENCODE 10 +166.1 166134 1.9 PKNOX1 NFRKB PTRF GATA2 ZNF280D ELF1 POLR2H TFDP1 MEF2D MAFF CCL2 CCL7 C17orf102 TMEM132E ASIC2 CCL1 CCL8 GC17P034446 GC17M034364
GH17F034637 1 Ensembl ENCODE 11.8 -58.6 -58621 1.4 CTCF KLF17 ZIC2 RAD21 ZNF766 STAT2 ZNF143 SMC3 ZNF600 EZH2 C17orf102 TMEM132E GC17M034614 GC17M034729
GH17F034886 1.1 Ensembl ENCODE 10.3 -307.7 -307655 0.5 HDAC1 PKNOX1 TBL1XR1 GATA2 SIRT6 CREM USF2 CEBPB ZEB2 ZNF589 TMEM132E C17orf102 GC17P034891 GC17P034858
GH17F034885 0.9 ENCODE 10.3 -305.9 -305908 0.2 HDAC1 ATF1 TBL1XR1 ELK1 GATA2 SIRT6 ETV6 CREM ZBTB11 NCOA1 C17orf102 TMEM132E GC17P034891 GC17P034858
GH17F034542 0.7 ENCODE 11.1 +36.5 36473 0.2 CTCF RAD21 ZKSCAN1 FOSL1 SCRT2 ZNF143 SMC3 SMARCE1 SCRT1 ZNF654 TMEM132E C17orf102 GC17M034550 LOC105371739
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C17orf102 on UCSC Golden Path with GeneCards custom track

Genomic Location for C17orf102 Gene

Chromosome:
17
Start:
34,574,123 bp from pter
End:
34,579,369 bp from pter
Size:
5,247 bases
Orientation:
Minus strand

Genomic View for C17orf102 Gene

Genes around C17orf102 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C17orf102 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C17orf102 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C17orf102 Gene

Proteins for C17orf102 Gene

  • Protein details for C17orf102 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A2RUQ5-CQ102_HUMAN
    Recommended name:
    Uncharacterized protein C17orf102
    Protein Accession:
    A2RUQ5
    Secondary Accessions:
    • A5PKX0
    • Q6ZTB3

    Protein attributes for C17orf102 Gene

    Size:
    167 amino acids
    Molecular mass:
    17761 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C17orf102 Gene

Post-translational modifications for C17orf102 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C17orf102 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C17orf102 Gene

Domains & Families for C17orf102 Gene

Protein Domains for C17orf102 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C17orf102: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C17orf102 Gene

Function for C17orf102 Gene

genes like me logo Genes that share phenotypes with C17orf102: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C17orf102 Gene

Localization for C17orf102 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C17orf102 gene
Compartment Confidence
mitochondrion 2
extracellular 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C17orf102 Gene

Pathways & Interactions for C17orf102 Gene

SuperPathways for C17orf102 Gene

No Data Available

Interacting Proteins for C17orf102 Gene

Selected Interacting proteins: A2RUQ5-CQ102_HUMAN for C17orf102 Gene via IID

Gene Ontology (GO) - Biological Process for C17orf102 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C17orf102 Gene

Transcripts for C17orf102 Gene

mRNA/cDNA for C17orf102 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C17orf102 Gene

Chromosome 17 open reading frame 102:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C17orf102 Gene

No ASD Table

Relevant External Links for C17orf102 Gene

GeneLoc Exon Structure for
C17orf102
ECgene alternative splicing isoforms for
C17orf102

Expression for C17orf102 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C17orf102 Gene

mRNA differential expression in normal tissues according to GTEx for C17orf102 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x10.3), Brain - Cortex (x9.5), Brain - Anterior cingulate cortex (BA24) (x6.1), Brain - Hypothalamus (x5.0), Brain - Cerebellar Hemisphere (x4.3), and Brain - Cerebellum (x4.3).

Protein differential expression in normal tissues from HIPED for C17orf102 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C17orf102 Gene



Protein tissue co-expression partners for C17orf102 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C17orf102 Gene:

C17orf102

SOURCE GeneReport for Unigene cluster for C17orf102 Gene:

Hs.514090
genes like me logo Genes that share expression patterns with C17orf102: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C17orf102 Gene

Orthologs for C17orf102 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C17orf102 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf102 34
  • 99.4 (n)
C17orf102 35
  • 98 (a)
OneToOne
Species where no ortholog for C17orf102 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C17orf102 Gene

ENSEMBL:
Gene Tree for C17orf102 (if available)
TreeFam:
Gene Tree for C17orf102 (if available)

Paralogs for C17orf102 Gene

No data available for Paralogs for C17orf102 Gene

Variants for C17orf102 Gene

Sequence variations from dbSNP and Humsavar for C17orf102 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs10048218 -- 34,574,087(+) TTATC(A/G)GGACT downstream-variant-500B
rs1014250 -- 34,575,608(-) CAGCT(C/T)AGATT utr-variant-3-prime
rs1019131 -- 34,573,943(-) CCTTG(C/T)GGAGG downstream-variant-500B
rs111571509 -- 34,579,045(+) CCCAG(A/C)GAACT upstream-variant-2KB, reference, missense
rs111619471 -- 34,580,430(+) GGCAT(C/T)CGGTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C17orf102 Gene

Variant ID Type Subtype PubMed ID
dgv3141n100 CNV gain 25217958
esv33292 CNV gain 17666407
esv3572553 CNV gain 25503493
esv3582611 CNV loss 25503493
nsv1055479 CNV gain 25217958
nsv519297 CNV gain 19592680
nsv574714 CNV gain 21841781

Variation tolerance for C17orf102 Gene

Residual Variation Intolerance Score: 80.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.82; 67.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C17orf102 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C17orf102

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C17orf102 Gene

Disorders for C17orf102 Gene

Relevant External Links for C17orf102

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C17orf102

No disorders were found for C17orf102 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C17orf102 Gene

Publications for C17orf102 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C17orf102 Gene

Sources for C17orf102 Gene

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