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Aliases for C16orf96 Gene

Aliases for C16orf96 Gene

  • Chromosome 16 Open Reading Frame 96 2 3 5

External Ids for C16orf96 Gene

Previous GeneCards Identifiers for C16orf96 Gene

  • GC16P004607

Summaries for C16orf96 Gene

GeneCards Summary for C16orf96 Gene

C16orf96 (Chromosome 16 Open Reading Frame 96) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C16orf96 Gene

Genomics for C16orf96 Gene

Regulatory Elements for C16orf96 Gene

Enhancers for C16orf96 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16F004894 0.6 FANTOM5 3.4 +356.3 356260 0.2 MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 FOS SP3 SP5 MXD4 LOC105371067 ENSG00000261789 LOC105371066 GLYR1 LINC01570 PPL UBN1 ENSG00000261442 C16orf96 SEPT12
GH16F004533 1 Ensembl ENCODE 0.8 -3.6 -3632 2.7 CTCF CBX3 SAP130 ZIC2 RAD21 ZNF335 ZFHX2 EED SMC3 ZNF548 NMRAL1 CREBBP ZNF500 HMOX2 MGRN1 C16orf96 ENSG00000278434
GH16F004536 1 FANTOM5 ENCODE 0.8 -0.5 -518 2.6 HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 SLC30A9 ZNF302 ZNF500 CDIP1 NMRAL1 CREBBP HMOX2 GLIS2 MGRN1 PPL C16orf96 ENSG00000278434
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C16orf96 on UCSC Golden Path with GeneCards custom track

Genomic Location for C16orf96 Gene

Chromosome:
16
Start:
4,538,709 bp from pter
End:
4,600,714 bp from pter
Size:
62,006 bases
Orientation:
Plus strand

Genomic View for C16orf96 Gene

Genes around C16orf96 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C16orf96 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C16orf96 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf96 Gene

Proteins for C16orf96 Gene

  • Protein details for C16orf96 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NNT2-CP096_HUMAN
    Recommended name:
    Uncharacterized protein C16orf96
    Protein Accession:
    A6NNT2
    Secondary Accessions:
    • C9JH24

    Protein attributes for C16orf96 Gene

    Size:
    1141 amino acids
    Molecular mass:
    125041 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C16orf96 Gene

Post-translational modifications for C16orf96 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C16orf96 Gene

No data available for DME Specific Peptides for C16orf96 Gene

Domains & Families for C16orf96 Gene

Protein Domains for C16orf96 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C16orf96: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C16orf96 Gene

Function for C16orf96 Gene

Phenotypes for C16orf96 Gene

GenomeRNAi human phenotypes for C16orf96:
genes like me logo Genes that share phenotypes with C16orf96: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C16orf96 Gene

Localization for C16orf96 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C16orf96 Gene COMPARTMENTS Subcellular localization image for C16orf96 gene
Compartment Confidence
cytosol 3
nucleus 2
plasma membrane 2
cytoskeleton 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C16orf96 Gene

Pathways & Interactions for C16orf96 Gene

SuperPathways for C16orf96 Gene

No Data Available

Interacting Proteins for C16orf96 Gene

Selected Interacting proteins: A6NNT2-CP096_HUMAN for C16orf96 Gene via IID

Symbol External ID(s) Details
ABCE1

Gene Ontology (GO) - Biological Process for C16orf96 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C16orf96 Gene

Transcripts for C16orf96 Gene

mRNA/cDNA for C16orf96 Gene

(4) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C16orf96 Gene

Chromosome 16 open reading frame 96:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf96 Gene

No ASD Table

Relevant External Links for C16orf96 Gene

GeneLoc Exon Structure for
C16orf96
ECgene alternative splicing isoforms for
C16orf96

Expression for C16orf96 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C16orf96 Gene

mRNA differential expression in normal tissues according to GTEx for C16orf96 Gene

This gene is overexpressed in Testis (x28.0).

Protein differential expression in normal tissues from HIPED for C16orf96 Gene

This gene is overexpressed in Heart (32.3) and Lung (15.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C16orf96 Gene



NURSA nuclear receptor signaling pathways regulating expression of C16orf96 Gene:

C16orf96

SOURCE GeneReport for Unigene cluster for C16orf96 Gene:

Hs.684212
genes like me logo Genes that share expression patterns with C16orf96: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C16orf96 Gene

Orthologs for C16orf96 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C16orf96 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C16H16orf96 34
  • 98.57 (n)
C16orf96 35
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C6H16orf96 34
  • 76.27 (n)
C16orf96 35
  • 50 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100361104 34
  • 66.14 (n)
mouse
(Mus musculus)
Mammalia 4930562C15Rik 34 16 35
  • 66.02 (n)
oppossum
(Monodelphis domestica)
Mammalia C16orf96 35
  • 36 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC768955 34
  • 50.66 (n)
Species where no ortholog for C16orf96 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C16orf96 Gene

ENSEMBL:
Gene Tree for C16orf96 (if available)
TreeFam:
Gene Tree for C16orf96 (if available)

Paralogs for C16orf96 Gene

No data available for Paralogs for C16orf96 Gene

Variants for C16orf96 Gene

Sequence variations from dbSNP and Humsavar for C16orf96 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs11076838 -- 4,545,882(+) tctcg(C/G)tctgt intron-variant
rs11076839 -- 4,550,664(+) CCTAC(A/G)TGGAG intron-variant
rs11076840 -- 4,553,764(+) GCCAC(A/G)GCGCC intron-variant
rs11076841 -- 4,580,992(+) ggtgg(C/T)gcatg intron-variant
rs11076842 -- 4,585,312(+) aaaaa(A/G)tccag intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C16orf96 Gene

Variant ID Type Subtype PubMed ID
esv32558 CNV gain 17666407
esv3581944 CNV loss 25503493
esv3637698 CNV loss 21293372
nsv1046986 CNV gain 25217958
nsv1160333 CNV deletion 26073780

Variation tolerance for C16orf96 Gene

Gene Damage Index Score: 10.00; 90.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C16orf96 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C16orf96

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C16orf96 Gene

Disorders for C16orf96 Gene

Relevant External Links for C16orf96

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C16orf96

No disorders were found for C16orf96 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C16orf96 Gene

Publications for C16orf96 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3 4 64
  2. ABCE1 is a highly conserved RNA silencing suppressor. (PMID: 25659154) KAorblane K. … Sarmiento C. (PLoS ONE 2015) 3 64
  3. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3 64

Products for C16orf96 Gene

Sources for C16orf96 Gene

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