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Aliases for C16orf96 Gene

Aliases for C16orf96 Gene

  • Chromosome 16 Open Reading Frame 96 2 3 5

External Ids for C16orf96 Gene

Previous GeneCards Identifiers for C16orf96 Gene

  • GC16P004607

Summaries for C16orf96 Gene

GeneCards Summary for C16orf96 Gene

C16orf96 (Chromosome 16 Open Reading Frame 96) is a Protein Coding gene.

Additional gene information for C16orf96 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C16orf96 Gene

Genomics for C16orf96 Gene

Regulatory Elements for C16orf96 Gene

Enhancers for C16orf96 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16H004536 1.8 FANTOM5 ENCODE dbSUPER 0.7 -0.5 -518 2 HDGF PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 SLC30A9 CDIP1 ZNF500 NMRAL1 ANKS3 ENSG00000261938 CREBBP EEF2KMT HMOX2 GLIS2-AS1 GLIS2
GH16H004533 1.1 Ensembl ENCODE dbSUPER 0.7 -3.5 -3534 2 ZFHX2 ZNF362 EED IKZF1 BATF IKZF2 EGR2 NMRAL1 HMOX2 MGRN1 ENSG00000278434 C16orf96
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C16orf96 on UCSC Golden Path with GeneCards custom track

Promoters for C16orf96 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000082834 -509 1601 HDGF PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 SLC30A9

Genomic Location for C16orf96 Gene

Chromosome:
16
Start:
4,538,709 bp from pter
End:
4,600,714 bp from pter
Size:
62,006 bases
Orientation:
Plus strand

Genomic View for C16orf96 Gene

Genes around C16orf96 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C16orf96 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C16orf96 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf96 Gene

Proteins for C16orf96 Gene

  • Protein details for C16orf96 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NNT2-CP096_HUMAN
    Recommended name:
    Uncharacterized protein C16orf96
    Protein Accession:
    A6NNT2
    Secondary Accessions:
    • C9JH24

    Protein attributes for C16orf96 Gene

    Size:
    1141 amino acids
    Molecular mass:
    125041 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C16orf96 Gene

Post-translational modifications for C16orf96 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C16orf96 Gene

No data available for DME Specific Peptides for C16orf96 Gene

Domains & Families for C16orf96 Gene

Gene Families for C16orf96 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C16orf96 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C16orf96: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C16orf96 Gene

Function for C16orf96 Gene

Phenotypes From GWAS Catalog for C16orf96 Gene

Phenotypes for C16orf96 Gene

GenomeRNAi human phenotypes for C16orf96:
genes like me logo Genes that share phenotypes with C16orf96: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C16orf96
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C16orf96 Gene

Localization for C16orf96 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C16orf96 gene
Compartment Confidence
cytosol 3
plasma membrane 2
nucleus 2
cytoskeleton 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C16orf96 Gene

Pathways & Interactions for C16orf96 Gene

SuperPathways for C16orf96 Gene

No Data Available

Interacting Proteins for C16orf96 Gene

Selected Interacting proteins: A6NNT2-CP096_HUMAN for C16orf96 Gene via IID

Symbol External ID(s) Details
ABCE1

Gene Ontology (GO) - Biological Process for C16orf96 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C16orf96 Gene

Drugs & Compounds for C16orf96 Gene

No Compound Related Data Available

Transcripts for C16orf96 Gene

mRNA/cDNA for C16orf96 Gene

(4) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C16orf96 Gene

Chromosome 16 open reading frame 96:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C16orf96
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf96 Gene

No ASD Table

Relevant External Links for C16orf96 Gene

GeneLoc Exon Structure for
C16orf96
ECgene alternative splicing isoforms for
C16orf96

Expression for C16orf96 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C16orf96 Gene

mRNA differential expression in normal tissues according to GTEx for C16orf96 Gene

This gene is overexpressed in Testis (x28.0).

Protein differential expression in normal tissues from HIPED for C16orf96 Gene

This gene is overexpressed in Heart (32.3) and Lung (15.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C16orf96 Gene



NURSA nuclear receptor signaling pathways regulating expression of C16orf96 Gene:

C16orf96

SOURCE GeneReport for Unigene cluster for C16orf96 Gene:

Hs.684212
genes like me logo Genes that share expression patterns with C16orf96: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C16orf96 Gene

Orthologs for C16orf96 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C16orf96 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C16H16orf96 33
  • 98.57 (n)
C16orf96 34
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C6H16orf96 33
  • 76.27 (n)
C16orf96 34
  • 50 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100361104 33
  • 66.14 (n)
mouse
(Mus musculus)
Mammalia 4930562C15Rik 33 16 34
  • 66.02 (n)
oppossum
(Monodelphis domestica)
Mammalia C16orf96 34
  • 36 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC768955 33
  • 50.66 (n)
Species where no ortholog for C16orf96 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C16orf96 Gene

ENSEMBL:
Gene Tree for C16orf96 (if available)
TreeFam:
Gene Tree for C16orf96 (if available)

Paralogs for C16orf96 Gene

No data available for Paralogs for C16orf96 Gene

Variants for C16orf96 Gene

Sequence variations from dbSNP and Humsavar for C16orf96 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000006921 -- 4,571,351(+) AATAC(A/G)GAGTT intron-variant
rs1000046113 -- 4,537,465(+) AAGCA(A/G)CAAAG intron-variant, upstream-variant-2KB
rs1000064970 -- 4,549,846(+) CTCAC(C/G)ATGCA intron-variant
rs1000110160 -- 4,542,030(+) GTTTA(C/G)ACCAA intron-variant
rs1000115649 -- 4,576,524(+) AGAGG(A/G)CTGTC reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C16orf96 Gene

Variant ID Type Subtype PubMed ID
esv32558 CNV gain 17666407
esv3581944 CNV loss 25503493
esv3637698 CNV loss 21293372
nsv1046986 CNV gain 25217958
nsv1160333 CNV deletion 26073780

Variation tolerance for C16orf96 Gene

Gene Damage Index Score: 10.00; 90.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C16orf96 Gene

Human Gene Mutation Database (HGMD)
C16orf96
SNPedia medical, phenotypic, and genealogical associations of SNPs for
C16orf96

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C16orf96 Gene

Disorders for C16orf96 Gene

Relevant External Links for C16orf96

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C16orf96

No disorders were found for C16orf96 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C16orf96 Gene

Publications for C16orf96 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 3 4 60
  2. ABCE1 is a highly conserved RNA silencing suppressor. (PMID: 25659154) Kärblane K … Sarmiento C (PloS one 2015) 3 60
  3. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie AG … Butte NF (PloS one 2012) 3 60

Products for C16orf96 Gene

Sources for C16orf96 Gene

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