Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C16orf92 Gene

Aliases for C16orf92 Gene

  • Chromosome 16 Open Reading Frame 92 2 3 5

External Ids for C16orf92 Gene

Previous GeneCards Identifiers for C16orf92 Gene

  • GC16P029944
  • GC16P027695

Summaries for C16orf92 Gene

GeneCards Summary for C16orf92 Gene

C16orf92 (Chromosome 16 Open Reading Frame 92) is a Protein Coding gene.

Additional gene information for C16orf92 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C16orf92 Gene

Genomics for C16orf92 Gene

Regulatory Elements for C16orf92 Gene

Enhancers for C16orf92 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16H029783 1.8 FANTOM5 Ensembl ENCODE dbSUPER 56.7 -238.9 -238850 2 PKNOX1 ATF1 MLX ZFP64 ARID4B DMAP1 YY1 TCF12 ZNF766 CBX5 C16orf92 NPIPB13 NPIPB12 SRCAP ENSG00000260853 ZNF747 INO80E SPNS1 SMG1P5 ATXN2L
GH16H030052 1.4 ENCODE dbSUPER 12.8 +30.9 30871 3 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 SP3 ZC3H11A SETD1A SRCAP INO80E NPIPB12 ZNF747 ZNF764 SMG1P5 SMG1P2 NPIPB13 BCL7C
GH16H029819 1.5 FANTOM5 ENCODE dbSUPER 10.9 -200.4 -200420 7 HDGF PKNOX1 SIN3A YY1 GLIS2 ZNF143 FOS RUNX3 PAF1 SP3 ENSG00000261766 SH2B1 ZNF785 ENSG00000260114 DOC2A TAOK2 TMEM219 HIRIP3 INO80E C16orf92
GH16H029992 1.2 ENCODE 12.6 -28.4 -28411 4 HDGF PKNOX1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B SETD1A SRCAP INO80E SMG1P5 SMG1P2 ENSG00000198106 BCL7C ZNF764 ZNF689 ZNF688
GH16H029828 1.2 Ensembl ENCODE 11.8 -193.3 -193305 3 ELF3 FOXA2 MLX ARID4B DMAP1 BMI1 DNMT3B ZSCAN9 RARA YY1 CDIPT-AS1 CDIPT C16orf92 FAM57B DOC2A TMEM219 HIRIP3 INO80E C16orf54 ZNF689
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C16orf92 on UCSC Golden Path with GeneCards custom track

Promoters for C16orf92 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000085141 -1934 801 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B ZNF143

Genomic Location for C16orf92 Gene

Chromosome:
16
Start:
30,023,334 bp from pter
End:
30,027,736 bp from pter
Size:
4,403 bases
Orientation:
Plus strand

Genomic View for C16orf92 Gene

Genes around C16orf92 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C16orf92 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C16orf92 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf92 Gene

Proteins for C16orf92 Gene

  • Protein details for C16orf92 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96LL3-CP092_HUMAN
    Recommended name:
    Uncharacterized protein C16orf92
    Protein Accession:
    Q96LL3
    Secondary Accessions:
    • Q494R8

    Protein attributes for C16orf92 Gene

    Size:
    132 amino acids
    Molecular mass:
    14383 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C16orf92 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C16orf92 Gene

Post-translational modifications for C16orf92 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C16orf92 Gene

No data available for DME Specific Peptides for C16orf92 Gene

Domains & Families for C16orf92 Gene

Gene Families for C16orf92 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for C16orf92 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C16orf92: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C16orf92 Gene

Function for C16orf92 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C16orf92
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C16orf92 Gene

Localization for C16orf92 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C16orf92 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C16orf92 gene
Compartment Confidence
plasma membrane 1
extracellular 1
mitochondrion 1
peroxisome 1
nucleus 1
cytosol 1

Gene Ontology (GO) - Cellular Components for C16orf92 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C16orf92: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for C16orf92 Gene

Pathways & Interactions for C16orf92 Gene

SuperPathways for C16orf92 Gene

No Data Available

Interacting Proteins for C16orf92 Gene

Gene Ontology (GO) - Biological Process for C16orf92 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C16orf92 Gene

Drugs & Compounds for C16orf92 Gene

No Compound Related Data Available

Transcripts for C16orf92 Gene

mRNA/cDNA for C16orf92 Gene

Unigene Clusters for C16orf92 Gene

Chromosome 16 open reading frame 92:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C16orf92
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf92 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4
SP1:
SP2: -

Relevant External Links for C16orf92 Gene

GeneLoc Exon Structure for
C16orf92
ECgene alternative splicing isoforms for
C16orf92

Expression for C16orf92 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C16orf92 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C16orf92 Gene

This gene is overexpressed in Testis (x37.6) and Brain - Cerebellum (x4.6).

NURSA nuclear receptor signaling pathways regulating expression of C16orf92 Gene:

C16orf92

SOURCE GeneReport for Unigene cluster for C16orf92 Gene:

Hs.651588
genes like me logo Genes that share expression patterns with C16orf92: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C16orf92 Gene

Orthologs for C16orf92 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C16orf92 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C16H16orf92 33
  • 99.09 (n)
C16orf92 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C6H16orf92 33
  • 78.48 (n)
C16orf92 34
  • 54 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C25H16orf92 33
  • 78.18 (n)
rat
(Rattus norvegicus)
Mammalia RGD1563217 33
  • 75.15 (n)
mouse
(Mus musculus)
Mammalia 4930451I11Rik 33 16 34
  • 73.39 (n)
Species where no ortholog for C16orf92 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C16orf92 Gene

ENSEMBL:
Gene Tree for C16orf92 (if available)
TreeFam:
Gene Tree for C16orf92 (if available)

Paralogs for C16orf92 Gene

No data available for Paralogs for C16orf92 Gene

Variants for C16orf92 Gene

Sequence variations from dbSNP and Humsavar for C16orf92 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000318863 -- 30,024,907(+) TCCCT(C/T)CCCAC downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime
rs1001399239 -- 30,023,561(+) AACCG(C/T)GAGCC intron-variant, upstream-variant-2KB
rs1002069923 -- 30,021,349(+) ACATG(C/T)CCGTG upstream-variant-2KB, utr-variant-5-prime
rs1002462729 -- 30,024,471(+) AGCAC(C/T)TCCCA upstream-variant-2KB, utr-variant-3-prime
rs1003154661 -- 30,022,934(+) CCCAC(C/T)TGGGT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C16orf92 Gene

Variant ID Type Subtype PubMed ID
nsv1160384 CNV duplication 26073780

Variation tolerance for C16orf92 Gene

Residual Variation Intolerance Score: 68.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.54; 11.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C16orf92 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C16orf92

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C16orf92 Gene

Disorders for C16orf92 Gene

Relevant External Links for C16orf92

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C16orf92

No disorders were found for C16orf92 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C16orf92 Gene

Publications for C16orf92 Gene

  1. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) Schizophrenia Working Group of the Psychiatric Genomics Consortium (Nature 2014) 3 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for C16orf92 Gene

Sources for C16orf92 Gene

Content
Loading form....