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Aliases for C16orf90 Gene

Aliases for C16orf90 Gene

  • Chromosome 16 Open Reading Frame 90 2 3 5

External Ids for C16orf90 Gene

Previous GeneCards Identifiers for C16orf90 Gene

  • GC16M003484
  • GC16M003543

Summaries for C16orf90 Gene

GeneCards Summary for C16orf90 Gene

C16orf90 (Chromosome 16 Open Reading Frame 90) is a Protein Coding gene.

Additional gene information for C16orf90 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C16orf90 Gene

Genomics for C16orf90 Gene

GeneHancer (GH) Regulatory Elements for C16orf90 Gene

Promoters and enhancers for C16orf90 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I003495 Promoter 0.5 EPDnew 550.8 +0.2 212 0.1 C16orf90 GC16P003504 RPL18P12 MIR6126 ENSG00000263212
GH16I003295 Enhancer 0.3 FANTOM5 45.4 +200.5 200524 0.1 C16orf90 ZNF263 ZNF200 MEFV OR2C1 ZNF174 ZSCAN32 SLX4 GC16P003498 ENSG00000279031
GH16I003214 Enhancer 0.6 Ensembl ENCODE 10.5 +280.0 279995 2.7 HLF HMBOX1 CBFA2T3 OR1F2P MEFV ZNF200 ZNF75A TIGD7 NAA60 ZNF597 ZNF174 ZSCAN32 OR2C1
GH16I003519 Enhancer 0.4 ENCODE 11.3 -24.8 -24821 1.9 RFX1 FOS NLRC3 RPL18P12 C16orf90 TRAP1 CREBBP ZNF200 DNASE1 ZNF205-AS1 ENSG00000278942 CLUAP1
GH16I003878 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE 1.5 -384.4 -384439 3.5 HDGF ATF1 ARID4B SIN3A ZNF2 YY1 ZNF207 ZNF143 SP5 MXD4 CREBBP C16orf90 ENSG00000262516
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C16orf90 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C16orf90 gene promoter:

Genomic Locations for C16orf90 Gene

Genomic Locations for C16orf90 Gene
chr16:3,493,484-3,495,721
(GRCh38/hg38)
Size:
2,238 bases
Orientation:
Minus strand
chr16:3,543,484-3,545,480
(GRCh37/hg19)

Genomic View for C16orf90 Gene

Genes around C16orf90 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C16orf90 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C16orf90 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf90 Gene

Proteins for C16orf90 Gene

  • Protein details for C16orf90 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MZG2-CP090_HUMAN
    Recommended name:
    Uncharacterized protein C16orf90
    Protein Accession:
    A8MZG2

    Protein attributes for C16orf90 Gene

    Size:
    172 amino acids
    Molecular mass:
    18426 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C16orf90 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C16orf90 Gene

Post-translational modifications for C16orf90 Gene

No Post-translational modifications

Other Protein References for C16orf90 Gene

No data available for DME Specific Peptides for C16orf90 Gene

Domains & Families for C16orf90 Gene

Gene Families for C16orf90 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted secreted proteins

Protein Domains for C16orf90 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C16orf90: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C16orf90 Gene

Function for C16orf90 Gene

Phenotypes for C16orf90 Gene

GenomeRNAi human phenotypes for C16orf90:
genes like me logo Genes that share phenotypes with C16orf90: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C16orf90 Gene

Localization for C16orf90 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C16orf90 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C16orf90 Gene

Pathways & Interactions for C16orf90 Gene

SuperPathways for C16orf90 Gene

No Data Available

Interacting Proteins for C16orf90 Gene

Gene Ontology (GO) - Biological Process for C16orf90 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C16orf90 Gene

Drugs & Compounds for C16orf90 Gene

No Compound Related Data Available

Transcripts for C16orf90 Gene

mRNA/cDNA for C16orf90 Gene

(6) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C16orf90 Gene

Chromosome 16 open reading frame 90:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf90 Gene

No ASD Table

Relevant External Links for C16orf90 Gene

GeneLoc Exon Structure for
C16orf90
ECgene alternative splicing isoforms for
C16orf90

Expression for C16orf90 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C16orf90 Gene

mRNA differential expression in normal tissues according to GTEx for C16orf90 Gene

This gene is overexpressed in Testis (x50.9).

NURSA nuclear receptor signaling pathways regulating expression of C16orf90 Gene:

C16orf90

SOURCE GeneReport for Unigene cluster for C16orf90 Gene:

Hs.632224
genes like me logo Genes that share expression patterns with C16orf90: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C16orf90 Gene

Orthologs for C16orf90 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C16orf90 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C16H16orf90 33
  • 99.63 (n)
C16orf90 34
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700037C18Rik 33 16 34
  • 85.54 (n)
rat
(Rattus norvegicus)
Mammalia RGD1561796 33
  • 84.9 (n)
dog
(Canis familiaris)
Mammalia C6H16orf90 33
  • 84.25 (n)
C16orf90 34
  • 66 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C25H16orf90 33
  • 84.21 (n)
C16orf90 34
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C16orf90 34
  • 39 (a)
OneToOne
Species where no ortholog for C16orf90 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C16orf90 Gene

ENSEMBL:
Gene Tree for C16orf90 (if available)
TreeFam:
Gene Tree for C16orf90 (if available)

Paralogs for C16orf90 Gene

No data available for Paralogs for C16orf90 Gene

Variants for C16orf90 Gene

Sequence variations from dbSNP and Humsavar for C16orf90 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000420994 -- 3,494,006(-) A/G intron_variant
rs1000452259 -- 3,493,770(-) C/T 3_prime_UTR_variant
rs1001140390 -- 3,494,707(-) G/C coding_sequence_variant, missense_variant
rs1001596488 -- 3,494,353(-) C/T intron_variant
rs1001969533 -- 3,495,264(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C16orf90 Gene

Variant ID Type Subtype PubMed ID
nsv952908 CNV deletion 24416366

Variation tolerance for C16orf90 Gene

Residual Variation Intolerance Score: 91% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C16orf90 Gene

Human Gene Mutation Database (HGMD)
C16orf90
SNPedia medical, phenotypic, and genealogical associations of SNPs for
C16orf90

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C16orf90 Gene

Disorders for C16orf90 Gene

Additional Disease Information for C16orf90

No disorders were found for C16orf90 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C16orf90 Gene

Publications for C16orf90 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  2. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 4 58

Products for C16orf90 Gene

Sources for C16orf90 Gene

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