Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



C16orf89 Gene

protein-coding   GIFtS: 42
GCID: GC16M005098

Chromosome 16 Open Reading Frame 89

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Chromosome 16 Open Reading Frame 891 2
UPF0764 Protein C16orf892

External Ids:    HGNC: 286871   Entrez Gene: 1465562   Ensembl: ENSG000001534467   UniProtKB: Q6UX733   

Export aliases for C16orf89 gene to outside databases

Previous GC identifer: GC16M005035


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for C16orf89 Gene:
This gene is expressed predominantly in the thyroid. Based on expression patterns similar to thyroid transcription
factors and proteins, this gene may function in the development and function of the thyroid. Multiple transcript
variants encoding different isoforms have been found for this gene. (provided by RefSeq, Oct 2011)

GeneCards Summary for C16orf89 Gene:
C16orf89 (chromosome 16 open reading frame 89) is a protein-coding gene. Diseases associated with C16orf89 include thyroiditis, and hepatitis.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000016.10  NT_010393.17  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the C16orf89 gene promoter:
         STAT1   p53   STAT4   STAT1beta   STAT5A   XBP-1   STAT1alpha   Zic1   STAT2   STAT3   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for C16orf89

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat C16orf89


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

C16orf89 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C16orf89 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M005098:  view genomic region     (about GC identifiers)

Start:
5,094,123 bp from pter      End:
5,116,111 bp from pter
Size:
21,989 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CP089_HUMAN, Q6UX73 (See protein sequence)
Recommended Name: UPF0764 protein C16orf89 precursor  
Size: 402 amino acids; 45391 Da
Subunit: Homodimer
Sequence caution: Sequence=AAH33681.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=AAQ88847.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAC11494.1;
Type=Miscellaneous discrepancy; Note=Aberrant splicing; Sequence=EAW85244.1; Type=Erroneous initiation;
Note=Translation N-terminally shortened;
Secondary accessions: B4DUM5 Q8N2I3 Q8N4T1
Alternative splicing: 2 isoforms:  Q6UX73-1   Q6UX73-2   (Major isoform, represents 80% of transcripts)

Explore the universe of human proteins at neXtProt for C16orf89: NX_Q6UX73

Explore proteomics data for C16orf89 at MOPED

Post-translational modifications: 

  • Glycosylated1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See C16orf89 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001091984.2  NP_689672.4  

    ENSEMBL proteins: 
     ENSP00000417158   ENSP00000420566   ENSP00000324672   ENSP00000390402   ENSP00000283478  

    C16orf89 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for C16orf89
    OriGene Protein Over-expression Lysate for C16orf89
    OriGene MassSpec for C16orf89
    OriGene Custom Protein Services for C16orf89
    GenScript Custom Purified and Recombinant Proteins Services for C16orf89
    Novus Biologicals C16orf89 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for C16orf89

    C16orf89 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for C16orf89
    Novus Biologicals C16orf89 Antibody
    Search for Antibodies for C16orf89 at Abcam
    Cloud-Clone Corp. Antibodies for C16orf89
    Search ThermoFisher Antibodies for C16orf89
    Search LSBio for Antibodies for C16orf89

    C16orf89 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for C16orf89
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for C16orf89
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for C16orf89
    Cloud-Clone Corp. CLIAs for C16orf89


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus

    ProtoNet protein and cluster: Q6UX73

    1 Blocks protein domain: IPB001545 Gonadotropin

    UniProtKB/Swiss-Prot: CP089_HUMAN, Q6UX73
    Similarity: Belongs to the UPF0764 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Phenotypes:
         1 MGI phenotypic allele for AU021092 (no phenotypes)

    C16orf89 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out AU021092tm1Lex for C16orf89

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for C16orf89
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for C16orf89

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for C16orf89
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for C16orf89

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat C16orf89 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate C16orf89:
    hsa-miR-3175
    SwitchGear 3'UTR luciferase reporter plasmidC16orf89 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for C16orf89
    Predesigned siRNA for gene silencing in human, mouse, rat C16orf89

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for C16orf89

    Clone
    Products:
         
    OriGene clones in human, mouse for C16orf89 (see all 10)
    OriGene ORF clones in mouse, rat for C16orf89
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): C16orf89 (NM_152459)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for C16orf89
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf89

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for C16orf89
    Browse ESI BIO Cell Lines and PureStem Progenitors for C16orf89 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf89


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    CP089_HUMAN, Q6UX73: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    cytoskeleton1
    cytosol1
    endoplasmic reticulum1
    golgi apparatus1
    lysosome1
    mitochondrion1
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0070062extracellular vesicular exosome IDA19056867

    C16orf89 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for C16orf89
    Interactions:

        Search GeneGlobe Interaction Network for C16orf89

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for C16orf89 (ENSP000002834784) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SRFENSP000002653544STRING: ENSP00000265354
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for C16orf89 (CP089)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for C16orf89 gene (2 alternative transcripts): 
    NM_001098514.2  NM_152459.4  

    Unigene Cluster for C16orf89:

    Chromosome 16 open reading frame 89
    Hs.11782  [show with all ESTs]
    Unigene Representative Sequence: NM_152459
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000586629 ENST00000474471 ENST00000472572 ENST00000315997 ENST00000592343
    ENST00000591875 ENST00000422873(uc002cyk.4) ENST00000350219(uc010bud.3)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat C16orf89 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate C16orf89:
    hsa-miR-3175
    SwitchGear 3'UTR luciferase reporter plasmidC16orf89 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for C16orf89
    Predesigned siRNA for gene silencing in human, mouse, rat C16orf89
    Clone
    Products:
         
    OriGene clones in human, mouse for C16orf89 (see all 10)
    OriGene ORF clones in mouse, rat for C16orf89
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): C16orf89 (NM_152459)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for C16orf89
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf89
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for C16orf89
    OriGene qSTAR qPCR primer pairs in human, mouse for C16orf89
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat C16orf89
      QuantiTect SYBR Green Assays in human, mouse, rat C16orf89
      QuantiFast Probe-based Assays in human, mouse, rat C16orf89

    Additional mRNA sequence: 

    AK075242.1 AK300708.1 AY358483.1 BC033681.1 

    4 DOTS entries:

    DT.100741932  DT.97793329  DT.210110  DT.75165060 

    Selected AceView cDNA sequences (see all 69):

    BF871021 BQ917270 BF871511 BM971997 BP349238 BI771576 BQ067424 BM921619 
    CD637847 AY358483 BM906008 BC033681 BG707780 AW070501 BF337477 BG702245 
    BU632344 AI433699 BX090681 N34942 BM663315 BQ722534 BM706955 AI478182 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for C16orf89    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b
    SP1:                                      -                                             
    SP2:                                      -                 -                           
    SP3:                                      -                 -                 -         
    SP4:                                                                                    


    ECgene alternative splicing isoforms for C16orf89

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    C16orf89 expression in normal human tissues (normalized intensities)      C16orf89 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCAGCTGCCT
    C16orf89 Expression
    About this image


    C16orf89 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Liver (Hepatobiliary System)
             Mature Mesothelial Cells Hepatic Mesenchyme
     
     Lung (Respiratory System)
     
     Thyroid (Endocrine System)
     
     Ovary (Reproductive System)
     
     Stomach (Gastrointestinal Tract)
    C16orf89 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    C16orf89 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.11782

    UniProtKB/Swiss-Prot: CP089_HUMAN, Q6UX73
    Tissue specificity: Predominantly expressed in thyroid tissue

        Custom PCR Arrays for C16orf89
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for C16orf89
    OriGene qSTAR qPCR primer pairs in human, mouse for C16orf89
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat C16orf89
    QuantiTect SYBR Green Assays in human, mouse, rat C16orf89
    QuantiFast Probe-based Assays in human, mouse, rat C16orf89
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf89

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for C16orf89 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia AU0210921 , 5 expressed sequence AU0210921, 5 78.02(n)1
    70.9(a)1
      16 (2.51 cM)5
    2396911  NM_001033220.31  NP_001028392.21 
     52118285 
    chicken
    (Gallus gallus)
    Aves C14H16ORF891 chromosome 14 open reading frame, human C16orf89 60.31(n)
    50.17(a)
      416394  XM_414708.4  XP_414708.2 
    zebrafish
    (Danio rerio)
    Actinopterygii si:ch211-76l23.71 si:ch211-76l23.7 50.8(n)
    42.17(a)
      566173  XM_689448.4  XP_694540.3 


    ENSEMBL Gene Tree for C16orf89 (if available)
    TreeFam Gene Tree for C16orf89 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for C16orf89 gene
    Selected SIMAP similar genes for C16orf89 using alignment to 2 protein entries:     CP089_HUMAN (see all proteins) (see all similar genes):
    ZNF169    LINC00596    NF2    AURA2    KIAA1651    FAM138C
    CASP7    AGBL3    DNAPTP3    FAM175A    HKR1    C4orf22
    GLT8D2    YTHDF3    EIF3L    GVQW1    OK/SW-cl.41    CTSS

    C16orf89 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for C16orf89 (see all 794)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1482489881,2
    Cuntested15045297(+) CTGTCC/TGTCCT 4 T syn10--------
    rs563735871,2
    C,F--5030394(+) CTTTAA/GGATAT 2 -- int17Minor allele frequency- G:0.20WA NA CSA EA 366
    rs740064061,2
    C,F--5030396(+) TTAAGA/GTATCA 2 -- int12Minor allele frequency- G:0.07WA 120
    rs1822721971,2
    --5030456(+) GTAATC/GCCAGC 2 -- int10--------
    rs353293391,2
    C,F--5030512(+) GAGACC/TAGCCA 2 -- int15Minor allele frequency- T:0.08NA WA 244
    rs1455997111,2
    --5030531(+) TAGTGA/GGATCC 2 -- int10--------
    rs1488791731,2
    --5030677(+) GACCTC/TATCTA 2 -- int10--------
    rs1425914721,2
    --5030736(+) AGTGGA/GATTGG 2 -- int10--------
    rs37438391,2
    C,F,H--5030798(-) TTGAGT/CCTTGT 2 -- int17Minor allele frequency- C:0.01EA NS NA 1166
    rs80572041,2
    C,H--5030879(+) TGGCCC/TTGCCT 2 -- ut3118Minor allele frequency- T:0.01NS EA NA WA CSA 773

    HapMap Linkage Disequilibrium report for C16orf89 (5094123 - 5116111 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for C16orf89 (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422516CNV Deletion17116639
    dgv477e199CNV Deletion23128226
    nsv905254CNV Loss21882294
    nsv1722CNV Loss18451855
    nsv827532CNV Loss20364138
    nsv457360CNV Loss19166990
    nsv9340CNV Loss18304495
    nsv817715CNV Gain17921354
    esv25186CNV Gain19812545
    nsv428318CNV Gain18775914

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing C16orf89
    DNA2.0 Custom Variant and Variant Library Synthesis for C16orf89

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    2 diseases for C16orf89:    About MalaCards
    thyroiditis    hepatitis


    C16orf89 for disorders           About GeneDecksing


    Export disorders for C16orf89 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for C16orf89 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with C16orf89)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Initial characterization of C16orf89, a novel thyroid-specific gene. (PubMed id 20578903)1, 2, 3 Afink G.B.... Ris-Stalpers C. (Thyroid 2010)
    2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (Genome Res. 2003)
    3. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    4. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    5. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. A transcript finishing initiative for closing gaps in the human transcriptome. (PubMed id 15197164)1 Sogayar M.C....Zanette D.L. (Genome Res. 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 146556 HGNC: 28687 AceView: MGC45438 Ensembl:ENSG00000153446 euGenes: HUgn146556
    ECgene: C16orf89 H-InvDB: C16orf89

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for C16orf89 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for C16orf89 gene:
    Search GeneIP for patents involving C16orf89

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for C16orf89  
     OriGene qPCR primer pairs and template standards for C16orf89   OriGene Protein Over-expression Lysate for C16orf89  
     OriGene MassSpec something-or-other for C16orf89   OriGene clones in human, mouse for C16orf89  
     OriGene qSTAR qPCR primer pairs in human, mouse for C16orf89   OriGene Purified Protein for C16orf89  
     OriGene ORF clones in mouse, rat for C16orf89   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for C16orf89   OriGene Custom Protein Services for C16orf89  

     
     
     Block miRNA regulation of human, mouse, rat C16orf89 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing C16orf89
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat C16orf89 Predesigned siRNA for gene silencing in human, mouse, rat C16orf89
     QuantiFast Probe-based Assays in human, mouse, rat C16orf89 QuantiTect SYBR Green Assays in human, mouse, rat C16orf89
     Custom PCR Arrays for C16orf89 Search Chromatin IP Primers for C16orf89
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat C16orf89  Search GeneGlobe Interaction Network for C16orf89
     Regulatory tfbs in C16orf89 promoter
     GenScript Custom Purified and Recombinant Proteins Services for C16orf89 GenScript cDNA clones with any tag delivered in your preferred vector for C16orf89
     GenScript Custom Assay Services for C16orf89 GenScript Custom overexpressing Cell Line Services for C16orf89
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for C16orf89 (CP089)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     C16orf89 antibodies
     C16orf89 lysates
     Search for Antibodies for C16orf89 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for C16orf89
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for C16orf89
     Antibodies for C16orf89
     ELISAs for C16orf89
     CLIAs for C16orf89



     Browse ESI BIO Cell Lines and PureStem Progenitors for C16orf89
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf89
     SwitchGear 3'UTR luciferase reporter plasmids for C16orf89
     Browse SwitchGear Promoter luciferase reporter plasmids for C16orf89
     Search ThermoFisher Antibodies for C16orf89
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf89
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for C16orf89
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for C16orf89
     Search LSBio for Antibodies for C16orf89
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      C16orf89 gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4