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Aliases for C16orf87 Gene

Aliases for C16orf87 Gene

  • Chromosome 16 Open Reading Frame 87 2 3 5

External Ids for C16orf87 Gene

Previous GeneCards Identifiers for C16orf87 Gene

  • GC16M045394
  • GC16M032725

Summaries for C16orf87 Gene

GeneCards Summary for C16orf87 Gene

C16orf87 (Chromosome 16 Open Reading Frame 87) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C16orf87 Gene

Genomics for C16orf87 Gene

Regulatory Elements for C16orf87 Gene

Enhancers for C16orf87 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G046756 1.4 FANTOM5 ENCODE dbSUPER 6.5 +74.0 73999 1.7 ZSCAN4 DMAP1 RAD21 ZNF2 ZNF335 ZNF121 SCRT2 GATAD2B REST NR2F2 SHCBP1 C16orf87 ORC6 GC16M046768 GC16P046705
GH16G046727 0.6 dbSUPER 4.2 +100.3 100269 6.8 SCRT1 NFIA BHLHE40 GATA3 JUND ZNF366 SCRT2 FOSL2 FOS SHCBP1 MYLK3 VPS35 ORC6 ANKRD26P1 C16orf87 GC16P046705 GC16M046768
GH16G046828 1.1 ENCODE 0.7 +0.9 944 3.4 PKNOX1 FOXA2 CREB3L1 MLX ARNT AGO1 SIN3A ARID4B DMAP1 YBX1 SHCBP1 C16orf87 GC16P046804
GH16G046832 0.8 ENCODE 0.7 -1.5 -1533 0.2 SOX13 SAP130 ARID4B CEBPG ZNF384 ZNF644 RARA YY1 ZNF664 NR2F6 ORC6 VPS35 GPT2 C16orf87 CKBP1
GH16G046826 0.6 Ensembl 0.7 +4.6 4601 0.4 SCRT1 PKNOX1 ARID3A MTA2 SCRT2 ZFP64 CEBPB JUNB FOS SP7 C16orf87 GC16P046804
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C16orf87 on UCSC Golden Path with GeneCards custom track

Promoters for C16orf87 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000085483 811 2801 PKNOX1 FOXA2 CREB3L1 MLX ARNT AGO1 SIN3A ARID4B DMAP1 YBX1

Genomic Location for C16orf87 Gene

Chromosome:
16
Start:
46,796,607 bp from pter
End:
46,831,411 bp from pter
Size:
34,805 bases
Orientation:
Minus strand

Genomic View for C16orf87 Gene

Genes around C16orf87 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C16orf87 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C16orf87 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf87 Gene

Proteins for C16orf87 Gene

  • Protein details for C16orf87 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PH81-CP087_HUMAN
    Recommended name:
    UPF0547 protein C16orf87
    Protein Accession:
    Q6PH81
    Secondary Accessions:
    • Q63HN9

    Protein attributes for C16orf87 Gene

    Size:
    154 amino acids
    Molecular mass:
    17799 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C16orf87 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C16orf87 Gene

Post-translational modifications for C16orf87 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C16orf87 Gene

No data available for DME Specific Peptides for C16orf87 Gene

Domains & Families for C16orf87 Gene

Protein Domains for C16orf87 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C16orf87 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6PH81

UniProtKB/Swiss-Prot:

CP087_HUMAN :
  • Belongs to the UPF0547 family.
Family:
  • Belongs to the UPF0547 family.
genes like me logo Genes that share domains with C16orf87: view

No data available for Gene Families for C16orf87 Gene

Function for C16orf87 Gene

Gene Ontology (GO) - Molecular Function for C16orf87 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 23752268
genes like me logo Genes that share ontologies with C16orf87: view

Phenotypes for C16orf87 Gene

genes like me logo Genes that share phenotypes with C16orf87: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C16orf87 Gene

Localization for C16orf87 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C16orf87 gene
Compartment Confidence
nucleus 4
plasma membrane 1
extracellular 1
mitochondrion 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C16orf87 Gene

Pathways & Interactions for C16orf87 Gene

SuperPathways for C16orf87 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C16orf87 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C16orf87 Gene

Drugs & Compounds for C16orf87 Gene

No Compound Related Data Available

Transcripts for C16orf87 Gene

Unigene Clusters for C16orf87 Gene

Chromosome 16 open reading frame 87:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf87 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b
SP1: - -
SP2:
SP3: - - -
SP4: -

Relevant External Links for C16orf87 Gene

GeneLoc Exon Structure for
C16orf87
ECgene alternative splicing isoforms for
C16orf87

Expression for C16orf87 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C16orf87 Gene

Protein differential expression in normal tissues from HIPED for C16orf87 Gene

This gene is overexpressed in Blymphocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C16orf87 Gene



Protein tissue co-expression partners for C16orf87 Gene

NURSA nuclear receptor signaling pathways regulating expression of C16orf87 Gene:

C16orf87

SOURCE GeneReport for Unigene cluster for C16orf87 Gene:

Hs.406551
genes like me logo Genes that share expression patterns with C16orf87: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C16orf87 Gene

Orthologs for C16orf87 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C16orf87 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C16ORF87 35
  • 100 (a)
OneToOne
C16H16orf87 34
  • 99.5 (n)
dog
(Canis familiaris)
Mammalia C16orf87 35
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C18H16orf87 34 35
  • 97.84 (n)
rat
(Rattus norvegicus)
Mammalia RGD1308706 34
  • 95.45 (n)
mouse
(Mus musculus)
Mammalia 4921524J17Rik 34 16 35
  • 95.02 (n)
oppossum
(Monodelphis domestica)
Mammalia C16orf87 35
  • 95 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C16orf87 35
  • 87 (a)
OneToOne
chicken
(Gallus gallus)
Aves C11H16ORF87 34 35
  • 86.58 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia c16orf87 34
  • 74.54 (n)
zebrafish
(Danio rerio)
Actinopterygii C7H16orf87 35
  • 77 (a)
OneToOne
zgc:92818 34
  • 71.27 (n)
Dr.14841 34
Species where no ortholog for C16orf87 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C16orf87 Gene

ENSEMBL:
Gene Tree for C16orf87 (if available)
TreeFam:
Gene Tree for C16orf87 (if available)

Paralogs for C16orf87 Gene

No data available for Paralogs for C16orf87 Gene

Variants for C16orf87 Gene

Sequence variations from dbSNP and Humsavar for C16orf87 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000035424 -- 46,814,961(+) ACTTC(C/T)TGATT intron-variant
rs1000366018 -- 46,828,361(+) AAATT(-/A)AAAAA intron-variant
rs1000401246 -- 46,820,344(+) TTCCT(C/T)GACTC intron-variant
rs1000432264 -- 46,820,673(+) GCTTC(A/G)TTGTG intron-variant
rs1000609758 -- 46,813,727(+) TGCCT(A/G)GAGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C16orf87 Gene

Variant ID Type Subtype PubMed ID
esv3571142 CNV gain 25503493
esv3638541 CNV gain 21293372
nsv1066115 CNV gain 25217958
nsv526656 CNV gain 19592680

Variation tolerance for C16orf87 Gene

Residual Variation Intolerance Score: 39.8% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C16orf87 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C16orf87

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C16orf87 Gene

Disorders for C16orf87 Gene

Relevant External Links for C16orf87

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C16orf87

No disorders were found for C16orf87 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C16orf87 Gene

Publications for C16orf87 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  3. The functional interactome landscape of the human histone deacetylase family. (PMID: 23752268) Joshi P. … Cristea I.M. (Mol. Syst. Biol. 2013) 3 64
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 64
  5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt K.T. … Blagoev B. (Sci. Signal. 2011) 4 64

Products for C16orf87 Gene

Sources for C16orf87 Gene

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