C16orf86 Gene
protein-coding GIFtS: 34
GCID: GC16P067701
|
|
chromosome 16 open reading frame 86
| |
Aliases for C16orf86 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Chromosome 16 Open Reading Frame 861 2 | | FLJ418021 | | Uncharacterized Protein C16orf862 |
Export aliases for C16orf86 gene to outside databasesPrevious GC identifers: GC16P066259 GC16P053573 |
Summaries for C16orf86 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Views for C16orf86 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the C16orf86 gene promoter: Pax-5 AML1a Nkx2-5 GATA-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for C16orf86
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C16orf86 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q22.1 Ensembl cytogenetic band: 16q22.1 HGNC cytogenetic band: 16q22.1C16orf86 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P067701: view genomic region
(about GC identifiers)
Start:
|
67,700,717 bp from pter |
End:
|
67,702,661 bp from pter |
Size:
|
1,945 bases |
Orientation:
|
plus strand |
|
Proteins for C16orf86 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: CP086_HUMAN, Q6ZW13 (See
protein sequence)Recommended Name: Uncharacterized protein C16orf86 Size: 317 amino acids; 33511 Da
Sequence caution: Sequence=BAC85694.1; Type=Miscellaneous discrepancy; Note=Intron retention;
Secondary accessions: B5MCW6Explore the universe of human proteins at neXtProt for C16orf86: NX_Q6ZW13
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6ZW13 C16orf86 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001013002.2 ENSEMBL proteins: ENSP00000384117 ENSP00000400874 Human Recombinant Protein Products:
C16orf86 Antibody Products: Assay Products for C16orf86: |
Protein
Domains / Families for C16orf86 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6ZW13 |
Function for C16orf86 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf86 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf86 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C16orf86 (NM_001012984) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C16orf86 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C16orf86  |
|
Pathways & Interactions for C16orf86 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C16orf86
|
Drugs & Compounds for C16orf86 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for C16orf86 Search CenterWatch for drugs/clinical trials and news about C16orf86 / CP086 
|
Transcripts for C16orf86 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for C16orf86 gene: NM_001012984.2 Unigene Cluster for C16orf86: Chromosome 16 open reading frame 86 Hs.632208 [show with all ESTs]Unigene Representative Sequence: AK1237963 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000403458(uc002ety.3) ENST00000459925(uc002etx.1) ENST00000445068(uc002etz.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf86 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf86 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C16orf86 (NM_001012984) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C16orf86 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C16orf86  |
Additional cDNA sequence: AK123796.1 BC032064.1 BC041612.1 BC064498.1 BC082249.1 BC132878.1 BC132880.1 5 DOTS entries: DT.209943 DT.95092461 DT.100754908 DT.100754907 DT.40284064 24/51 AceView cDNA sequences (see all 51): AW166505 BF508140 AW439937 CA432406 BC082249 BM714516 BC064498 BC041612 AW511004 AI085633 BU147275 BQ683738 BC032064 AK123796 AI948664 CB852223 BU623874 BM725142 BF509374 BQ716271 CA396890 CB305679 BM042333 AI471025 GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for C16orf86 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | |
| SP1: | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | - |   | |   | |   | |   | |
| SP3: | |   | |   | - |   | |   | |   | |   | |
| SP4: | |   | |   | - |   | - |   | |   | |   |
ECgene alternative splicing isoforms for C16orf86
|
Expression for C16orf86 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C16orf86 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CCCTGGCTCC
About this image See C16orf86 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for C16orf86
SOURCE GeneReport for Unigene cluster: Hs.632208 SABiosciences Custom PCR Arrays for C16orf86
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C16orf86 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C16orf86 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C16orf86 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C16orf86 |
Orthologs for C16orf86 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C16orf86 gene from 1/5 species (see all 5) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
4933405L10Rik1 , 5 |
RIKEN cDNA 4933405L10 gene1, 5 |
73.33(n)1 67.46(a)1 |
  |
8 (53.04 cM)5 710461 NM_027655.11 NP_081931.11 1057083035 |
ENSEMBL Gene Tree for C16orf86 (if available) TreeFam Gene Tree for C16orf86 (if available)  |
Paralogs for C16orf86 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for C16orf86 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 16 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for C16orf86 (67700717 - 67702661 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for C16orf86: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C16orf86 |
|
Disorders
/ Diseases for C16orf86 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications for C16orf86 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C16orf86 gene integrated from 9 sources: (articles sorted by number of sources associating them with C16orf86) | |  | Utopia: connect your pdf to the dynamic world of online information |
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for C16orf86 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing C16orf86 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C16orf86 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C16orf86 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for C16orf86 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C16orf86 gene: Search GeneIP for patents involving C16orf86
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for C16orf86 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C16orf86 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C16orf86 | | OriGene Protein Over-expression Lysate for C16orf86 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for C16orf86 | | OriGene 3'-UTR Clone for C16orf86 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf86 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf86 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for C16orf86 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for C16orf86 | | OriGene Custom Protein Services for C16orf86 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C16orf86 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C16orf86 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C16orf86 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C16orf86 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C16orf86 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C16orf86 |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | C16orf86 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | Search ThermoFisher Antibodies for C16orf86 |
| | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C16orf86 |
|
|
|
|