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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C16orf82 Gene

RNA gene   GIFtS: 36
GCID: GC16P026986

chromosome 16 open reading frame 82

 Explore 3 diseases affiliated with
C16orf82 via our new
 Human Malady Compendium 
Biological research products
for C16orf82
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Subcategory (RNA class): lncRNA

Quality score for this RNA gene is 3

Aliases
Chromosome 16 Open Reading Frame 821 2
TNT1 2
Protein TNT2

External Ids:    HGNC: 307551   Entrez Gene: 1620832   Ensembl: ENSG000002341867   UniProtKB: Q7Z2V13   

Export aliases for C16orf82 gene to outside databases

Previous GC identifer: GC16P025167


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the C16orf82 gene promoter:
         c-Fos   AP-1   CUTL1   RORalpha2   RORalpha1   CBF-B   Nkx6-1   c-Myb   c-Jun   TGIF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidC16orf82 promoter sequence
   Search SABiosciences Chromatin IP Primers for C16orf82

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C16orf82


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.1   Ensembl cytogenetic band:  16p12.1   HGNC cytogenetic band: 16p12.1

C16orf82 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C16orf82 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P026986:  view genomic region     (about GC identifiers)

Start:
27,078,028 bp from pter      End:
27,080,487 bp from pter
Size:
2,460 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TNT_HUMAN, Q7Z2V1 (See protein sequence)
Recommended Name: Protein TNT  
Size: 217 amino acids; 23111 Da
Secondary accessions: B9EGC2 Q8NEF0

Explore the universe of human proteins at neXtProt for C16orf82: NX_Q7Z2V1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q7Z2V1

  • C16orf82 Protein expression data from MOPED and PaxDb: --
    REFSEQ proteins: NP_001139017.1  
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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q7Z2V1


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    miRNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C16orf82

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for C16orf82
    Search CenterWatch for drugs/clinical trials and news about C16orf82 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
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    About This Section

    REFSEQ mRNAs for C16orf82 gene (2 alternative transcripts): 
    NM_182831.1  NM_001145545.1  

    Unigene Cluster for C16orf82:

    Chromosome 16 open reading frame 82
    Hs.120831  [show with all ESTs]
    Unigene Representative Sequence: AF536240
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000505035(lincRNA) ENST00000418886(lincRNA)(uc010vcm.2)

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    Additional cDNA sequence: 

    AF536240.1 AK311574.1 BC031257.1 BC136370.1 BC136382.1 

    1 DOTS entry:

    DT.101979239 

    24/44 AceView cDNA sequences (see all 44):

    AA399310 AA709253 AA398244 BI828977 AA758821 AI636668 AA723645 BI519998 
    BI825506 AA401777 CD171808 BI827317 AL042417 AL044140 AL042391 BU854276 
    AW515660 AI147451 BM908109 AI656343 AF536240 BC031257 BI828894 AI190733 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    Expression evidence for C16orf82:none

    C16orf82 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTGACAGAGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    Genevestigator expression for C16orf82

    SOURCE GeneReport for Unigene cluster: Hs.120831

    UniProtKB/Swiss-Prot: TNT_HUMAN, Q7Z2V1
    Tissue specificity: Preferentially expressed in teratocarcinoma rather than in normal testis

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for C16orf82 (if available)
    TreeFam Gene Tree for C16orf82 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/127 NCBI SNPs in C16orf82 are shown (see all 127    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1409429651,2
    --27076225(+) TCATTA/TAGTTT 1 -- us2k10--------
    rs1415365641,2
    --27076237(+) TATTCC/TGGCTG 1 -- us2k10--------
    rs1146278901,2
    C,--27076286(+) TGTCAC/TAAGGA 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1156475681,2
    C,F,--27076330(+) CAGGGG/ACCAGG 1 -- us2k11Minor allele frequency- A:0.08WA 118
    rs112684101,2
    C,--27076382(+) AGGCA-/AGCCGATGA
    CCTGGGGTCAGG
    AGTTC
    1 -- us2k10--------
    rs1505319251,2
    --27076397(+) CCAGCA/CTGGCC 1 -- us2k10--------
    rs1907993471,2
    --27076522(+) GAGGCA/GGAGGT 1 -- us2k10--------
    rs1836209091,2
    --27076608(+) GGAGTG/TGGGGA 1 -- us2k10--------
    rs2014745301,2
    --27076620(+) CCAGG-/CACGGT
    GGCTCACAC
    CTGTA
    1 -- us2k10--------
    rs1395384471,2
    --27076674(+) TCGGGA/GGTTTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for C16orf82 (27078028 - 27080487 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for C16orf82: --

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    C16orf82 for disorders           About GeneDecksing

    3 diseases for C16orf82:    About MalaCards
    nemaline myopathy    teratocarcinoma    myopathy

    1 disease from the University of Copenhagen DISEASES database for C16orf82:
    Nemaline myopathy

    Export disorders for C16orf82 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for C16orf82 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with C16orf82)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    3. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
    4. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
    5. Parasites, proteomics and performance: effects of gregarine gut parasites on dragonfly flight muscle composition and function. (PubMed id 18055619)9 Schilder R.J. and Marden J.H. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 162083 HGNC: 30755 AceView: TNT Ensembl:ENSG00000234186 euGenes: HUgn162083
    ECgene: C16orf82 H-InvDB: C16orf82

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for C16orf82 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for C16orf82 gene:
    Search GeneIP for patents involving C16orf82

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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