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Aliases for C16orf72 Gene

Aliases for C16orf72 Gene

  • Chromosome 16 Open Reading Frame 72 2 3 5
  • PRO0149 3

External Ids for C16orf72 Gene

Previous GeneCards Identifiers for C16orf72 Gene

  • GC16P009094
  • GC16P009185
  • GC16P009106

Summaries for C16orf72 Gene

GeneCards Summary for C16orf72 Gene

C16orf72 (Chromosome 16 Open Reading Frame 72) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C16orf72 Gene

Genomics for C16orf72 Gene

Regulatory Elements for C16orf72 Gene

Promoters for C16orf72 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C16orf72 on UCSC Golden Path with GeneCards custom track

Genomic Location for C16orf72 Gene

Chromosome:
16
Start:
9,091,648 bp from pter
End:
9,121,640 bp from pter
Size:
29,993 bases
Orientation:
Plus strand

Genomic View for C16orf72 Gene

Genes around C16orf72 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C16orf72 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C16orf72 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf72 Gene

Proteins for C16orf72 Gene

  • Protein details for C16orf72 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14CZ0-CP072_HUMAN
    Recommended name:
    UPF0472 protein C16orf72
    Protein Accession:
    Q14CZ0

    Protein attributes for C16orf72 Gene

    Size:
    275 amino acids
    Molecular mass:
    30926 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C16orf72 Gene

Proteomics data for C16orf72 Gene at MOPED

Post-translational modifications for C16orf72 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C16orf72 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C16orf72 Gene

Domains & Families for C16orf72 Gene

Protein Domains for C16orf72 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C16orf72 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q14CZ0

UniProtKB/Swiss-Prot:

CP072_HUMAN :
  • Belongs to the UPF0472 family.
Family:
  • Belongs to the UPF0472 family.
genes like me logo Genes that share domains with C16orf72: view

No data available for Gene Families for C16orf72 Gene

Function for C16orf72 Gene

genes like me logo Genes that share phenotypes with C16orf72: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C16orf72 Gene

Localization for C16orf72 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C16orf72 Gene COMPARTMENTS Subcellular localization image for C16orf72 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C16orf72 Gene

Pathways & Interactions for C16orf72 Gene

SuperPathways for C16orf72 Gene

No Data Available

Interacting Proteins for C16orf72 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000331720%0d%0a9606.ENSP00000318716%0d%0a9606.ENSP00000385269%0d%0a9606.ENSP00000262854%0d%0a
Selected Interacting proteins: Q14CZ0-CP072_HUMAN ENSP00000331720 for C16orf72 Gene via UniProtKB STRING

Gene Ontology (GO) - Biological Process for C16orf72 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C16orf72 Gene

Drugs & Compounds for C16orf72 Gene

No Compound Related Data Available

Transcripts for C16orf72 Gene

mRNA/cDNA for C16orf72 Gene

Unigene Clusters for C16orf72 Gene

Chromosome 16 open reading frame 72:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf72 Gene

No ASD Table

Relevant External Links for C16orf72 Gene

GeneLoc Exon Structure for
C16orf72
ECgene alternative splicing isoforms for
C16orf72

Expression for C16orf72 Gene

mRNA expression in normal human tissues for C16orf72 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C16orf72 Gene

This gene is overexpressed in Whole Blood (x4.4).

SOURCE GeneReport for Unigene cluster for C16orf72 Gene Hs.221497

genes like me logo Genes that share expression patterns with C16orf72: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C16orf72 Gene

Orthologs for C16orf72 Gene

This gene was present in the common ancestor of animals.

Orthologs for C16orf72 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C16orf72 36
  • 99 (a)
OneToOne
C16H16orf72 35
  • 99.24 (n)
  • 98.46 (a)
cow
(Bos Taurus)
Mammalia C25H16ORF72 36
  • 100 (a)
OneToOne
C25H16orf72 35
  • 97.7 (n)
  • 100 (a)
dog
(Canis familiaris)
Mammalia C16orf72 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1810013L24Rik 16
1810013L24Rik 35
  • 97.09 (n)
  • 98.55 (a)
1810013L24Rik 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C16orf72 36
  • 97 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C16orf72 36
  • 95 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1309748 35
  • 96.24 (n)
  • 98.55 (a)
chicken
(Gallus gallus)
Aves LOC416639 35
  • 88.03 (n)
  • 91.12 (a)
C16orf72 36
  • 94 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C16orf72 36
  • 82 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia MGC68553 35
tropical clawed frog
(Silurana tropicalis)
Amphibia c16orf72 35
  • 84.38 (n)
  • 92.91 (a)
Str.5950 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3294 35
zebrafish
(Danio rerio)
Actinopterygii C3H16orf72 36
  • 83 (a)
OneToOne
wufb59e09 35
zgc:77849 35
  • 75.63 (n)
  • 86.56 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4768 36
  • 32 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.11201 36
  • 44 (a)
OneToOne
Species with no ortholog for C16orf72:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C16orf72 Gene

ENSEMBL:
Gene Tree for C16orf72 (if available)
TreeFam:
Gene Tree for C16orf72 (if available)

Paralogs for C16orf72 Gene

Pseudogenes.org Pseudogenes for C16orf72 Gene

genes like me logo Genes that share paralogs with C16orf72: view

No data available for Paralogs for C16orf72 Gene

Variants for C16orf72 Gene

Sequence variations from dbSNP and Humsavar for C16orf72 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs34869458 - 9,116,746(-) TAGCA(C/T)TCGAT reference, missense
rs6777 -- 9,119,562(+) TGTTT(A/C)ATATT utr-variant-3-prime
rs9039 -- 9,111,506(-) TACAC(A/G)GAAAA intron-variant, utr-variant-3-prime
rs11450 -- 9,111,505(-) ACACA(A/G)AAAAT intron-variant, utr-variant-3-prime
rs1133686 -- 9,105,179(+) AGCAA(A/T)GATAC intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for C16orf72 Gene

Variant ID Type Subtype PubMed ID
dgv2600n71 CNV Gain 21882294
nsv457400 CNV Gain 19166990
nsv525864 CNV Loss 19592680
nsv457401 CNV Gain 19166990
nsv519065 CNV Gain 19592680
nsv457402 CNV Gain 19166990

Variation tolerance for C16orf72 Gene

Residual Variation Intolerance Score: 59% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.91; 48.86% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C16orf72 Gene

HapMap Linkage Disequilibrium report
C16orf72

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C16orf72 Gene

Disorders for C16orf72 Gene

Relevant External Links for C16orf72

Genetic Association Database (GAD)
C16orf72
Human Genome Epidemiology (HuGE) Navigator
C16orf72
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C16orf72

No disorders were found for C16orf72 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C16orf72 Gene

Publications for C16orf72 Gene

  1. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 2 3 67
  2. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. (PMID: 25737280) Murn J. … Shi Y. (Genes Dev. 2015) 3
  3. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R. … Iakoucheva L.M. (Nat. Commun. 2014) 3
  4. Quantitative Lys-I/-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1. (PMID: 25147182) Thompson J.W. … Luchansky S.J. (J. Biol. Chem. 2014) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for C16orf72 Gene

Sources for C16orf72 Gene

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