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C16orf70 Gene

protein-coding   GIFtS: 50
GCID: GC16P067143

Chromosome 16 Open Reading Frame 70

(Previous name: chromosome 16 open reading frame 6)
(Previous symbols: C16orf6, LIN10)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Chromosome 16 Open Reading Frame 701 2     lin-102
C16orf61 2 3     Lin-10 Homolog2
LIN101 2     UPF0183 Protein C16orf702
Chromosome 16 Open Reading Frame 61     

External Ids:    HGNC: 295641   Entrez Gene: 802622   Ensembl: ENSG000001251497   UniProtKB: Q9BSU13   

Export aliases for C16orf70 gene to outside databases

Previous GC identifers: GC16P065703 GC16P053017


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for C16orf70 Gene:
C16orf70 (chromosome 16 open reading frame 70) is a protein-coding gene. Diseases associated with C16orf70 include chronic lymphocytic leukemia, and ataxia.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000016.10  NT_010498.16  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the C16orf70 gene promoter:
         Nkx3-1   ISGF-3   Nkx3-1 v4   Nkx3-1 v1   Nkx3-1 v2   POU2F1   POU2F1a   Nkx3-1 v3   FOXO1a   FOXO1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for C16orf70

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat C16orf70


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22.1

C16orf70 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C16orf70 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P067143:  view genomic region     (about GC identifiers)

Start:
67,143,861 bp from pter      End:
67,182,442 bp from pter
Size:
38,582 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CP070_HUMAN, Q9BSU1 (See protein sequence)
Recommended Name: UPF0183 protein C16orf70  
Size: 422 amino acids; 47524 Da
Caution: Was originally (Ref.1) thought to be a lin-10 homolog
Secondary accessions: Q9HA86
Alternative splicing: 2 isoforms:  Q9BSU1-1   Q9BSU1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for C16orf70: NX_Q9BSU1

Explore proteomics data for C16orf70 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys231
  • Modification sites at PhosphoSitePlus

  • See C16orf70 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079463.2  
    ENSEMBL proteins: 
     ENSP00000456688   ENSP00000456549   ENSP00000455182   ENSP00000219139   ENSP00000456154  
     ENSP00000464242  

    C16orf70 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for C16orf70

    C16orf70 Antibody Products:

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    Abcam antibodies for C16orf70
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    LSBio Antibodies in human, mouse, rat for C16orf70

    C16orf70 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for C16orf70
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    Cloud-Clone Corp. ELISAs for C16orf70
    Cloud-Clone Corp. CLIAs for C16orf70


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR005373 UPF0183

    Graphical View of Domain Structure for InterPro Entry Q9BSU1

    ProtoNet protein and cluster: Q9BSU1

    1 Blocks protein domain: IPB005373 Protein of unknown function UPF0183

    UniProtKB/Swiss-Prot: CP070_HUMAN, Q9BSU1
    Similarity: Belongs to the UPF0183 family


    C16orf70 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16713569
         
    C16orf70 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for C16orf70
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for C16orf70
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for C16orf70

    miRNA
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    miRTarBase miRNAs that target C16orf70:
    hsa-mir-30c-5p (MIRT048021), hsa-mir-130b-3p (MIRT020232), hsa-mir-185-5p (MIRT045383), hsa-mir-19b-3p (MIRT031183), hsa-mir-93-5p (MIRT028063)

    Block miRNA regulation of human, mouse, rat C16orf70 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate C16orf70 (see all 51):
    hsa-miR-106a hsa-miR-301a hsa-miR-218 hsa-miR-9 hsa-miR-93 hsa-miR-526b* hsa-miR-130b hsa-miR-2113
    SwitchGear 3'UTR luciferase reporter plasmidC16orf70 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for C16orf70
    Predesigned siRNA for gene silencing in human, mouse, rat C16orf70

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for C16orf70 (see all 7)
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    GenScript: all cDNA clones in your preferred vector: C16orf70 (NM_025187)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for C16orf70
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf70

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf70


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    golgi apparatus1
    mitochondrion1
    peroxisome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for C16orf70
    Interactions:

        Search GeneGlobe Interaction Network for C16orf70

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for C16orf70 (Q9BSU11, 2, 3 ENSP000002191394) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN3P542521, 2, 3, ENSP000003523244EBI-946080,EBI-946046 MINT-2876621 MINT-2855422 I2D: score=3 STRING: ENSP00000352324
    CASKO149363, ENSP000003674084I2D: score=2 STRING: ENSP00000367408
    KIF17Q9P2E23, ENSP000002479864I2D: score=1 STRING: ENSP00000247986
    CTSAP106193I2D: score=4 
    EIF2B1Q142323I2D: score=4 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for C16orf70 (CP070)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for C16orf70 gene: 
    NM_025187.3  

    Unigene Cluster for C16orf70:

    Chromosome 16 open reading frame 70
    Hs.513666  [show with all ESTs]
    Unigene Representative Sequence: BC004556
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000563853 ENST00000569914 ENST00000569600 ENST00000219139(uc002erc.3 uc002erd.3)
    ENST00000569683 ENST00000566026 ENST00000569626(uc002ere.1) ENST00000565900
    ENST00000561683 ENST00000567162 ENST00000569277
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat C16orf70 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate C16orf70 (see all 51):
    hsa-miR-106a hsa-miR-301a hsa-miR-218 hsa-miR-9 hsa-miR-93 hsa-miR-526b* hsa-miR-130b hsa-miR-2113
    SwitchGear 3'UTR luciferase reporter plasmidC16orf70 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for C16orf70
    Predesigned siRNA for gene silencing in human, mouse, rat C16orf70
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    OriGene ORF clones in mouse, rat for C16orf70
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: C16orf70 (NM_025187)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for C16orf70
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf70
    Primer
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    OriGene qPCR primer pairs and template standards for C16orf70
    OriGene qSTAR qPCR primer pairs in human, mouse for C16orf70
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat C16orf70
      QuantiTect SYBR Green Assays in human, mouse, rat C16orf70
      QuantiFast Probe-based Assays in human, mouse, rat C16orf70

    Additional mRNA sequence: 

    AF176088.1 AK022138.1 BC004556.2 

    15 DOTS entries:

    DT.315793  DT.95114678  DT.97805418  DT.100721424  DT.100740054  DT.307136  DT.70103743  DT.95096481 
    DT.91767275  DT.95114681  DT.95140381  DT.95217944  DT.97808949  DT.40108627  DT.99971070 

    Selected AceView cDNA sequences (see all 112):

    BM693740 BQ947236 AU121257 AL540304 CB216088 AI493703 NM_025187 AI241146 
    BQ653957 CB216610 CA428545 AI805093 CB997191 AI023696 BM555224 BQ653132 
    BU176819 CF265194 AI453251 BE671868 BC004556 AI401752 BQ028528 CA417705 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for C16orf70    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17
    SP1:                                                                          -     -                                                         
    SP2:        -                       -                 -                                                                                       
    SP3:                                -                                                                                                         
    SP4:                                                                                                                                          
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for C16orf70

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    C16orf70 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCTGTTGCT
    C16orf70 Expression
    About this image

    C16orf70 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    C16orf70 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.513666
        Custom PCR Arrays for C16orf70
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf70

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for C16orf70 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia D230025D16Rik1 , 5 RIKEN cDNA D230025D16 gene1, 5 92.02(n)1
    96.92(a)1
      8 (53.04 cM)5
    2346781  NM_145604.21  NP_663579.21 
     1052251455 
    chicken
    (Gallus gallus)
    Aves C11H16ORF701 chromosome 11 open reading frame, human C16orf70 83.57(n)
    94.55(a)
      415699  NM_001030565.1  NP_001025736.1 
    lizard
    (Anolis carolinensis)
    Reptilia C16orf706
    chromosome 16 open reading frame 70
    87(a)
    1 ↔ 1
    5(108524322-108577328)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004941151 chromosome unknown open reading frame, human C16orf7 more 77.22(n)
    85.48(a)
      100494115  XM_002937167.2  XP_002937213.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-102f14.51 si:dkey-102f14.5 76.35(n)
    88.1(a)
      557406  NM_001082813.1  NP_001076282.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG70831 CG7083 57.17(n)
    56.76(a)
      38943  NM_139954.2  NP_648211.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T01G9.21 T01G9.2 46.38(n)
    38.62(a)
      172609  NM_059851.3  NP_492252.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G511301 AT3G51130 49.86(n)
    38.38(a)
      824277  NM_114973.2  NP_566945.1 
    rice
    (Oryza sativa)
    Liliopsida Os06g07140001 Os06g0714000 49.28(n)
    38.86(a)
      4342057  NM_001065105.1  NP_001058570.1 


    ENSEMBL Gene Tree for C16orf70 (if available)
    TreeFam Gene Tree for C16orf70 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for C16orf70 gene

    C16orf70 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for C16orf70
    PGOHUM00000263224


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for C16orf70 (see all 572)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1502463931,2
    --67141959(+) CAGCTA/GCCCAA 1 -- us2k10--------
    rs1859858701,2
    --67142198(+) TTTTTC/TCTCTT 1 -- us2k10--------
    rs1903368181,2
    --67142284(+) GCTCTG/TTCATC 1 -- us2k10--------
    rs1815234811,2
    --67142415(+) GCTAAA/TTTTTT 1 -- us2k10--------
    rs724542361,2
    C--67142564(+) ATATC-/TCTA  
            
    TCTAT
    1 -- us2k10--------
    rs1120330741,2
    C--67142602(+) CTATCT/-ATCTA 1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs80622191,2
    C,F,A,H--67142631(+) atctaT/Catcac 1 -- us2k1 tfbs311Minor allele frequency- C:0.11NS EA NA WA 1204
    rs1874316581,2
    --67142671(+) TCTCAA/GTGACC 1 -- us2k10--------
    rs1156061751,2
    C,F--67142678(+) GACCCA/CGTTCT 1 -- us2k11Minor allele frequency- C:0.02WA 118
    rs1389166671,2
    --67142707(+) GCTGCA/GGTGGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for C16orf70 (67143861 - 67182442 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for C16orf70:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv509627CNV Insertion20534489
    nsv906794CNV Loss21882294
    dgv2886n71CNV Loss21882294
    nsv827707CNV Loss20364138
    nsv524363CNV Loss19592680
    dgv2887n71CNV Loss21882294
    dgv2885n71CNV Loss21882294
    dgv2888n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing C16orf70
    DNA2.0 Custom Variant and Variant Library Synthesis for C16orf70

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    4 diseases for C16orf70:    
    About MalaCards
    chronic lymphocytic leukemia    ataxia    malaria    leukemia


    C16orf70 for disorders           About GeneDecksing

    Genetic Association Database (GAD): C16orf70
    Human Genome Epidemiology (HuGE) Navigator: C16orf70 (5 documents)

    Export disorders for C16orf70 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for C16orf70 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with C16orf70)
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    1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    2. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (Occup Environ Med 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    9. Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. (PubMed id 21048031)1 Casabonne D....de Sanjose S. (Haematologica 2011)
    10. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 80262 HGNC: 29564 AceView: Lin10 Ensembl:ENSG00000125149 euGenes: HUgn80262
    ECgene: C16orf70 H-InvDB: C16orf70

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for C16orf70 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for C16orf70 gene:
    Search GeneIP for patents involving C16orf70

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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