Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C16orf70 Gene

protein-coding   GIFtS: 48
GCID: GC16P067143

Chromosome 16 Open Reading Frame 70

(Previous name: chromosome 16 open reading frame 6)
(Previous symbols: C16orf6, LIN10)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Chromosome 16 Open Reading Frame 701 2     lin-102
C16orf61 2 3     Lin-10 Homolog2
LIN101 2     UPF0183 Protein C16orf702
Chromosome 16 Open Reading Frame 61     

External Ids:    HGNC: 295641   Entrez Gene: 802622   Ensembl: ENSG000001251497   UniProtKB: Q9BSU13   

Export aliases for C16orf70 gene to outside databases

Previous GC identifers: GC16P065703 GC16P053017


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for C16orf70 Gene: 
C16orf70 (chromosome 16 open reading frame 70) is a protein-coding gene. Diseases associated with C16orf70 include chronic lymphocytic leukemia, and leukemia. GO annotations related to this gene include protein binding.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the C16orf70 gene promoter:
         Nkx3-1   ISGF-3   Nkx3-1 v4   Nkx3-1 v1   Nkx3-1 v2   POU2F1   POU2F1a   Nkx3-1 v3   FOXO1a   FOXO1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for C16orf70

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C16orf70


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22.1

C16orf70 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C16orf70 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P067143:  view genomic region     (about GC identifiers)

Start:
67,143,861 bp from pter      End:
67,182,442 bp from pter
Size:
38,582 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CP070_HUMAN, Q9BSU1 (See protein sequence)
Recommended Name: UPF0183 protein C16orf70  
Size: 422 amino acids; 47524 Da
Caution: Was originally (Ref.1) thought to be a lin-10 homolog
Secondary accessions: Q9HA86
Alternative splicing: 2 isoforms:  Q9BSU1-1   Q9BSU1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for C16orf70: NX_Q9BSU1

Explore proteomics data for C16orf70 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BSU1

  • C16orf70 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    C16orf70 Protein Expression
    REFSEQ proteins: NP_079463.2  
    ENSEMBL proteins: 
     ENSP00000456688   ENSP00000456549   ENSP00000455182   ENSP00000219139   ENSP00000456154  
     ENSP00000464242  

    Human Recombinant Protein Products for C16orf70: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for C16orf70
    OriGene Protein Over-expression Lysate for C16orf70
    OriGene MassSpec for C16orf70 
    OriGene Custom Protein Services for C16orf70
    GenScript Custom Purified and Recombinant Proteins Services for C16orf70
    Novus Biologicals C16orf70 Protein
    Novus Biologicals C16orf70 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for C16orf70 


    C16orf70 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for C16orf70
    GenScript Custom Superior Antibodies Services for C16orf70
    Novus Biologicals C16orf70 Antibodies
    Abcam antibodies for C16orf70
    Cloud-Clone Corp. Antibodies for C16orf70 
    ThermoFisher Antibodies for C16orf70
    LSBio Antibodies in human, mouse, rat for C16orf70 

    Assay Products for C16orf70: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for C16orf70
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for C16orf70
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for C16orf70 
    Cloud-Clone Corp. CLIAs for C16orf70


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR005373 UPF0183

    Graphical View of Domain Structure for InterPro Entry Q9BSU1

    ProtoNet protein and cluster: Q9BSU1

    1 Blocks protein domain: IPB005373 Protein of unknown function UPF0183

    UniProtKB/Swiss-Prot: CP070_HUMAN, Q9BSU1
    Similarity: Belongs to the UPF0183 family


    C16orf70 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16713569
         
    C16orf70 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for C16orf70 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for C16orf70

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for C16orf70 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for C16orf70 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C16orf70
    8/51 QIAGEN miScript miRNA Assays for microRNAs that regulate C16orf70 (see all 51):
    hsa-miR-106a hsa-miR-301a hsa-miR-218 hsa-miR-9 hsa-miR-93 hsa-miR-526b* hsa-miR-130b hsa-miR-2113
    SwitchGear 3'UTR luciferase reporter plasmidC16orf70 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for C16orf70
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C16orf70

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for C16orf70
    Sirion Biotech Customized adenovirus for overexpression of C16orf70

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for C16orf70 (see all 8)
    OriGene ORF clones in mouse, rat for C16orf70
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: C16orf70 (NM_025187)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for C16orf70
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf70
    Sirion Biotech Customized lentivirus for stable overexpression of C16orf70 
                         Customized lentivirus expression plasmids for stable overexpression of C16orf70 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for C16orf70
    Search LifeMap BioReagents cell lines for C16orf70
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf70


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C16orf70

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/8 Interacting proteins for C16orf70 (Q9BSU11, 2, 3 ENSP000002191394) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN3P542521, 2, 3, ENSP000003523244EBI-946080,EBI-946046 MINT-2876621 MINT-2855422 I2D: score=3 STRING: ENSP00000352324
    CASKO149363, ENSP000003674084I2D: score=2 STRING: ENSP00000367408
    KIF17Q9P2E23, ENSP000002479864I2D: score=1 STRING: ENSP00000247986
    CTSAP106193I2D: score=4 
    EIF2B1Q142323I2D: score=4 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for C16orf70 (CP070)

    Search CenterWatch for drugs/clinical trials and news about C16orf70 / CP070

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for C16orf70 gene: 
    NM_025187.3  

    Unigene Cluster for C16orf70:

    Chromosome 16 open reading frame 70
    Hs.513666  [show with all ESTs]
    Unigene Representative Sequence: BC004556
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000563853 ENST00000569914 ENST00000569600 ENST00000219139(uc002erc.3 uc002erd.3)
    ENST00000569683 ENST00000566026 ENST00000569626(uc002ere.1) ENST00000565900
    ENST00000561683 ENST00000567162 ENST00000569277
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C16orf70
    8/51 QIAGEN miScript miRNA Assays for microRNAs that regulate C16orf70 (see all 51):
    hsa-miR-106a hsa-miR-301a hsa-miR-218 hsa-miR-9 hsa-miR-93 hsa-miR-526b* hsa-miR-130b hsa-miR-2113
    SwitchGear 3'UTR luciferase reporter plasmidC16orf70 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for C16orf70
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C16orf70
    Clone
    Products:
         
    OriGene clones in human, mouse for C16orf70 (see all 8)
    OriGene ORF clones in mouse, rat for C16orf70
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: C16orf70 (NM_025187)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for C16orf70
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf70
    Sirion Biotech Customized lentivirus for stable overexpression of C16orf70 
                         Customized lentivirus expression plasmids for stable overexpression of C16orf70 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for C16orf70
    OriGene qSTAR qPCR primer pairs in human, mouse for C16orf70
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C16orf70
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C16orf70
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C16orf70

    Additional mRNA sequence: 

    AF176088.1 AK022138.1 BC004556.2 

    15 DOTS entries:

    DT.315793  DT.95114678  DT.97805418  DT.100721424  DT.100740054  DT.307136  DT.70103743  DT.95096481 
    DT.91767275  DT.95114681  DT.95140381  DT.95217944  DT.97808949  DT.40108627  DT.99971070 

    24/112 AceView cDNA sequences (see all 112):

    BQ947236 AF176088 CA417705 BM693740 AI805093 AU121257 AI493500 AI493703 
    NM_025187 AI241146 BE671868 CA428545 AI453251 CF265194 CB997191 BQ653132 
    CB216610 BM555224 CB216088 AI336870 AI023696 BC004556 BG697911 BQ028528 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for C16orf70    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17
    SP1:                                                                          -     -                                                         
    SP2:        -                       -                 -                                                                                       
    SP3:                                -                                                                                                         
    SP4:                                                                                                                                          
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for C16orf70

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    C16orf70 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCTGTTGCT
    C16orf70 Expression
    About this image


    See C16orf70 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for C16orf70

    SOURCE GeneReport for Unigene cluster: Hs.513666
        SABiosciences Custom PCR Arrays for C16orf70
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for C16orf70
    OriGene qSTAR qPCR primer pairs in human, mouse for C16orf70
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C16orf70
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C16orf70
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C16orf70
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf70

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for C16orf70 gene from 8/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia D230025D16Rik1 , 5 RIKEN cDNA D230025D16 gene1, 5 92.02(n)1
    96.92(a)1
      8 (53.04 cM)5
    2346781  NM_145604.21  NP_663579.21 
     1052251455 
    chicken
    (Gallus gallus)
    Aves C11H16orf701 chromosome 11 open reading frame, human C16orf70 83.57(n)
    94.55(a)
      415699  NM_001030565.1  NP_001025736.1 
    lizard
    (Anolis carolinensis)
    Reptilia C16ORF706
    Uncharacterized protein
    87(a)
    1 ↔ 1
    5(108524322-108577328)
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-102f14.51 si:dkey-102f14.5 76.35(n)
    88.1(a)
      557406  NM_001082813.1  NP_001076282.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG70831 CG7083 57.17(n)
    56.76(a)
      38943  NM_139954.2  NP_648211.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T01G9.21 Protein T01G9.2 46.29(n)
    38.11(a)
      172609  NM_059851.2  NP_492252.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G511301 hypothetical protein 50.28(n)
    39.04(a)
      824277  NM_114973.2  NP_566945.1 
    rice
    (Oryza sativa)
    Liliopsida Os06g07140001 hypothetical protein 48.65(n)
    37.84(a)
      4342057  NM_001065105.1  NP_001058570.1 


    ENSEMBL Gene Tree for C16orf70 (if available)
    TreeFam Gene Tree for C16orf70 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for C16orf70 gene

    C16orf70 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for C16orf70
    PGOHUM00000263224


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/572 SNPs in C16orf70 are shown (see all 572)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1502463931,2
    --67141959(+) CAGCTA/GCCCAA 1 -- us2k10--------
    rs1859858701,2
    --67142198(+) TTTTTC/TCTCTT 1 -- us2k10--------
    rs1903368181,2
    --67142284(+) GCTCTG/TTCATC 1 -- us2k10--------
    rs1815234811,2
    --67142415(+) GCTAAA/TTTTTT 1 -- us2k10--------
    rs724542361,2
    C--67142564(+) ATATC-/TCTA  
            
    TCTAT
    1 -- us2k10--------
    rs1120330741,2
    C--67142602(+) CTATCT/-ATCTA 1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs80622191,2
    C,F,A,H--67142631(+) atctaT/Catcac 1 -- us2k1 tfbs311Minor allele frequency- C:0.11NS EA NA WA 1204
    rs1874316581,2
    --67142671(+) TCTCAA/GTGACC 1 -- us2k10--------
    rs1156061751,2
    C,F--67142678(+) GACCCA/CGTTCT 1 -- us2k11Minor allele frequency- C:0.02WA 118
    rs1389166671,2
    --67142707(+) GCTGCA/GGTGGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for C16orf70 (67143861 - 67182442 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for C16orf70:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv509627CNV Insertion20534489
    nsv906794CNV Loss21882294
    dgv2886n71CNV Loss21882294
    nsv827707CNV Loss20364138
    nsv524363CNV Loss19592680
    dgv2887n71CNV Loss21882294
    dgv2885n71CNV Loss21882294
    dgv2888n71CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing C16orf70
    DNA2.0 Custom Variant and Variant Library Synthesis for C16orf70

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for C16orf70:    About MalaCards
    chronic lymphocytic leukemia    leukemia


    C16orf70 for disorders           About GeneDecksing

    Genetic Association Database (GAD): C16orf70
    Human Genome Epidemiology (HuGE) Navigator: C16orf70 (5 documents)

    Export disorders for C16orf70 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for C16orf70 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with C16orf70)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    2. Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. Single nucleotide polymorphisms of matrix metalloprot einase 9 (MMP-9) and tumour protein 73 (TP73) interact with Epstein Barr virus in chronic lymphocytic leukemia: results from the European case-control study E piLymph. (PubMed id 21048031)1 Casabonne D....de Sanjose S. (2010)
    10. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80262 HGNC: 29564 AceView: Lin10 Ensembl:ENSG00000125149 euGenes: HUgn80262
    ECgene: C16orf70 H-InvDB: C16orf70

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for C16orf70 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for C16orf70 gene:
    Search GeneIP for patents involving C16orf70

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for C16orf70  
     OriGene qPCR primer pairs and template standards for C16orf70   OriGene Protein Over-expression Lysate for C16orf70  
     OriGene MassSpec something-or-other for C16orf70   OriGene clones in human, mouse for C16orf70  
     OriGene qSTAR qPCR primer pairs in human, mouse for C16orf70   OriGene Purified Protein for C16orf70  
     OriGene ORF clones in mouse, rat for C16orf70   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for C16orf70   OriGene Custom Protein Services for C16orf70  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C16orf70
     QIAGEN SeqTarget long-range PCR primers for resequencing C16orf70
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C16orf70
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C16orf70
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C16orf70
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C16orf70
     GenScript Custom Purified and Recombinant Proteins Services for C16orf70 GenScript cDNA clones with any tag delivered in your preferred vector for C16orf70
     GenScript Custom Assay Services for C16orf70 GenScript Custom Superior Antibodies Services for C16orf70
     GenScript Custom overexpressing Cell Line Services for C16orf70 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in C16orf70 promoter
     Search Chromatin IP Primers for C16orf70
     RT2 qPCR Primer Assay in human, mouse, rat C16orf70
     Search GNC Networks for C16orf70
     SABiosciences Custom PCR Arrays for C16orf70
     Search Tocris compounds for C16orf70 (CP070)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     C16orf70 antibodies
     C16orf70 proteins
     C16orf70 lysates
     Antibodies for C16orf70
     See all of Abcam's Antibodies, Kits and Proteins for C16orf70
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for C16orf70
     Antibodies for C16orf70
     ELISAs for C16orf70
     CLIAs for C16orf70
     Search LifeMap BioReagents cell lines for C16orf70
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf70
     SwitchGear 3'UTR luciferase reporter plasmids for C16orf70
     Browse SwitchGear Promoter luciferase reporter plasmids for C16orf70
     ThermoFisher Antibodies for C16orf70
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf70
     inGenious Targeting Laboratory - Custom generated mouse model solutions for C16orf70
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for C16orf70
    Customized:
     lentivirus for stable overexpression of C16orf70
     lentivirus expression plasmids for stable overexpression of C16orf70
     adenovirus for overexpression of C16orf70
     LSBio Antibodies in human, mouse, rat for C16orf70
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      C16orf70 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4