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Aliases for C16orf59 Gene

Aliases for C16orf59 Gene

  • Chromosome 16 Open Reading Frame 59 2 3

External Ids for C16orf59 Gene

Previous GeneCards Identifiers for C16orf59 Gene

  • GC16P002451
  • GC16P002512

Summaries for C16orf59 Gene

GeneCards Summary for C16orf59 Gene

C16orf59 (Chromosome 16 Open Reading Frame 59) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C16orf59 Gene

Genomics for C16orf59 Gene

Regulatory Elements for C16orf59 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C16orf59 Gene

2,460,080 bp from pter
2,464,963 bp from pter
4,884 bases
Plus strand

Genomic View for C16orf59 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C16orf59 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf59 Gene

Proteins for C16orf59 Gene

  • Protein details for C16orf59 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C16orf59
    Protein Accession:
    Secondary Accessions:
    • B4DXD7
    • Q96H61
    • Q9H872

    Protein attributes for C16orf59 Gene

    433 amino acids
    Molecular mass:
    46402 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C16orf59 Gene


neXtProt entry for C16orf59 Gene

Proteomics data for C16orf59 Gene at MOPED

Post-translational modifications for C16orf59 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C16orf59 Gene

No data available for DME Specific Peptides for C16orf59 Gene

Domains & Families for C16orf59 Gene

Protein Domains for C16orf59 Gene


Suggested Antigen Peptide Sequences for C16orf59 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C16orf59: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C16orf59 Gene

Function for C16orf59 Gene

Gene Ontology (GO) - Molecular Function for C16orf59 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C16orf59: view
genes like me logo Genes that share phenotypes with C16orf59: view

Animal Model Products

CRISPR Products

miRNA for C16orf59 Gene

miRTarBase miRNAs that target C16orf59

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C16orf59

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for C16orf59 Gene

Localization for C16orf59 Gene

Subcellular locations from

Jensen Localization Image for C16orf59 Gene COMPARTMENTS Subcellular localization image for C16orf59 gene
Compartment Confidence
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C16orf59 Gene

Pathways & Interactions for C16orf59 Gene

SuperPathways for C16orf59 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C16orf59 Gene


No data available for Pathways by source and SIGNOR curated interactions for C16orf59 Gene

Drugs & Compounds for C16orf59 Gene

No Compound Related Data Available

Transcripts for C16orf59 Gene

Unigene Clusters for C16orf59 Gene

Chromosome 16 open reading frame 59:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C16orf59

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf59 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11
SP1: - - -
SP2: - - -
SP3: - -
SP4: - -
SP5: - - -
SP6: - -
SP8: -

Relevant External Links for C16orf59 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C16orf59 Gene

mRNA expression in normal human tissues for C16orf59 Gene

mRNA differential expression in normal tissues according to GTEx for C16orf59 Gene

This gene is overexpressed in Testis (x5.0).

Protein differential expression in normal tissues from HIPED for C16orf59 Gene

This gene is overexpressed in Lung (37.0), Saliva (18.3), and Heart (13.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for C16orf59 Gene

SOURCE GeneReport for Unigene cluster for C16orf59 Gene Hs.534491

genes like me logo Genes that share expression patterns with C16orf59: view

Protein tissue co-expression partners for C16orf59 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C16orf59 Gene

Orthologs for C16orf59 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C16orf59 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C25H16orf59 35
  • 79.76 (n)
  • 70.82 (a)
C16orf59 36
  • 67 (a)
(Canis familiaris)
Mammalia C6H16orf59 35
  • 78.38 (n)
  • 71.23 (a)
C16orf59 36
  • 74 (a)
(Mus musculus)
Mammalia 1600002H07Rik 35
  • 72.69 (n)
  • 63.38 (a)
1600002H07Rik 16
1600002H07Rik 36
  • 61 (a)
(Pan troglodytes)
Mammalia C16H16orf59 35
  • 98.69 (n)
  • 98.38 (a)
C16orf59 36
  • 98 (a)
(Rattus norvegicus)
Mammalia LOC100158225 35
  • 73.11 (n)
  • 65.09 (a)
(Monodelphis domestica)
Mammalia C16orf59 36
  • 36 (a)
(Gallus gallus)
Aves C16orf59 36
  • 34 (a)
(Anolis carolinensis)
Reptilia C16orf59 36
  • 32 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100485766 35
  • 44.74 (n)
  • 33.49 (a)
Species with no ortholog for C16orf59:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C16orf59 Gene

Gene Tree for C16orf59 (if available)
Gene Tree for C16orf59 (if available)

Paralogs for C16orf59 Gene

No data available for Paralogs for C16orf59 Gene

Variants for C16orf59 Gene

Sequence variations from dbSNP and Humsavar for C16orf59 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
VAR_032115 -

Structural Variations from Database of Genomic Variants (DGV) for C16orf59 Gene

Variant ID Type Subtype PubMed ID
esv2422427 CNV Duplication 17116639
dgv2545n71 CNV Loss 21882294
nsv905139 CNV Loss 21882294
nsv833121 CNV Loss 17160897
dgv2569n71 CNV Loss 21882294
dgv2570n71 CNV Loss 21882294
nsv905149 CNV Loss 21882294
nsv905152 CNV Loss 21882294
nsv905153 CNV Loss 21882294
nsv827513 CNV Gain 20364138

Variation tolerance for C16orf59 Gene

Residual Variation Intolerance Score: 30.25% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.33; 26.45% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C16orf59 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C16orf59 Gene

Disorders for C16orf59 Gene

Relevant External Links for C16orf59

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C16orf59: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C16orf59 Gene

Publications for C16orf59 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  4. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 67
  5. FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region. (PMID: 16484223) Assmann E.M. … Kobarg J. (J. Biol. Chem. 2006) 67

Products for C16orf59 Gene

Sources for C16orf59 Gene

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