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Aliases for C16orf58 Gene

Aliases for C16orf58 Gene

  • Chromosome 16 Open Reading Frame 58 2 3
  • RUS1 Family Protein C16orf58 3
  • UPF0420 Protein C16orf58 3
  • RUS 3

External Ids for C16orf58 Gene

Summaries for C16orf58 Gene

Entrez Gene Summary for C16orf58 Gene

  • This gene encodes a putative transmembrane protein containing a conserved DUF647 domain that may be involved in protein-protein interaction. The encoded protein is related to a plant protein that participates in ultraviolet B light-sensing during root morphogenesis. [provided by RefSeq, Feb 2013]

GeneCards Summary for C16orf58 Gene

C16orf58 (Chromosome 16 Open Reading Frame 58) is a Protein Coding gene.

Gene Wiki entry for C16orf58 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C16orf58 Gene

Genomics for C16orf58 Gene

Genomic Location for C16orf58 Gene

Start:
31,489,471 bp from pter
End:
31,509,309 bp from pter
Size:
19,839 bases
Orientation:
Minus strand

Genomic View for C16orf58 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C16orf58 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf58 Gene

Regulatory Elements for C16orf58 Gene

Proteins for C16orf58 Gene

  • Protein details for C16orf58 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96GQ5-RUS1_HUMAN
    Recommended name:
    RUS1 family protein C16orf58
    Protein Accession:
    Q96GQ5
    Secondary Accessions:
    • Q53GL8
    • Q8NAJ4
    • Q9BVY3
    • Q9H887

    Protein attributes for C16orf58 Gene

    Size:
    468 amino acids
    Molecular mass:
    51018 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C16orf58 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C16orf58 Gene

Proteomics data for C16orf58 Gene at MOPED

Post-translational modifications for C16orf58 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys297, Lys376, Lys433, Lys436, Lys465, and Lys466

Other Protein References for C16orf58 Gene

No data available for DME Specific Peptides for C16orf58 Gene

Domains for C16orf58 Gene

Protein Domains for C16orf58 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

RUS1_HUMAN
Family:
  • Belongs to the RUS1 family.:
    • Q96GQ5
genes like me logo Genes that share domains with C16orf58: view

No data available for Gene Families for C16orf58 Gene

Function for C16orf58 Gene

miRNA for C16orf58 Gene

miRTarBase miRNAs that target C16orf58

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C16orf58 Gene

Localization for C16orf58 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C16orf58 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C16orf58 Gene COMPARTMENTS Subcellular localization image for C16orf58 gene
Compartment Confidence
cytosol 2
golgi apparatus 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for C16orf58 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IDA 19946888
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C16orf58: view

Pathways for C16orf58 Gene

SuperPathways for C16orf58 Gene

No Data Available

Interacting Proteins for C16orf58 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000317579%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000317579 Q96GQ5-RUS1_HUMAN for C16orf58 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for C16orf58 Gene

None

No data available for Pathways by source for C16orf58 Gene

Transcripts for C16orf58 Gene

Unigene Clusters for C16orf58 Gene

Chromosome 16 open reading frame 58:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf58 Gene

No ASD Table

Relevant External Links for C16orf58 Gene

GeneLoc Exon Structure for
C16orf58
ECgene alternative splicing isoforms for
C16orf58

Expression for C16orf58 Gene

mRNA expression in normal human tissues for C16orf58 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C16orf58 Gene

SOURCE GeneReport for Unigene cluster for C16orf58 Gene Hs.9003

genes like me logo Genes that share expressions with C16orf58: view

Orthologs for C16orf58 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for C16orf58 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C16H16orf58 36
  • 99.43 (n)
  • 99.36 (a)
C16orf58 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C16orf58 37
  • 82 (a)
OneToOne
C25H16orf58 36
  • 88.07 (n)
  • 83.68 (a)
dog
(Canis familiaris)
Mammalia C16orf58 37
  • 68 (a)
OneToOne
C6H16orf58 36
  • 86.54 (n)
  • 85.47 (a)
mouse
(Mus musculus)
Mammalia BC017158 36
  • 83.98 (n)
  • 81.33 (a)
BC017158 16
BC017158 37
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C16orf58 37
  • 68 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C16orf58 37
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1310127 36
  • 82.47 (n)
  • 80.9 (a)
lizard
(Anolis carolinensis)
Reptilia C16orf58 37
  • 52 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101732099 36
  • 61.32 (n)
  • 61.32 (a)
Str.20322 36
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.4481 36
zebrafish
(Danio rerio)
Actinopterygii C3H16orf58 37
  • 50 (a)
OneToOne
Dr.12463 36
zgc:162613 36
  • 57.04 (n)
  • 54.9 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010020 36
  • 48.69 (n)
  • 43.54 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG10338 36
  • 53.39 (n)
  • 44.29 (a)
CG10338 37
  • 38 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons RUS3 36
  • 48.65 (n)
  • 43.45 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.5264 36
Species with no ortholog for C16orf58:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C16orf58 Gene

ENSEMBL:
Gene Tree for C16orf58 (if available)
TreeFam:
Gene Tree for C16orf58 (if available)

Paralogs for C16orf58 Gene

Pseudogenes.org Pseudogenes for C16orf58 Gene

genes like me logo Genes that share paralogs with C16orf58: view

No data available for Paralogs for C16orf58 Gene

Variants for C16orf58 Gene

Sequence variations from dbSNP and Humsavar for C16orf58 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs3934739 -- 31,501,765(+) GACCA(C/T)AGTGA intron-variant
rs4536493 -- 31,492,430(+) GCCCC(A/G)AGACC intron-variant
rs4889664 -- 31,504,889(+) cggtg(C/T)aggat intron-variant
rs6565234 -- 31,503,789(+) tcctg(C/T)gtagc intron-variant
rs6565235 -- 31,505,192(+) gatgt(C/T)tgggt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C16orf58 Gene

Variant ID Type Subtype PubMed ID
nsv833194 CNV Loss 17160897
nsv905747 CNV Gain 21882294
dgv2673n71 CNV Loss 21882294
nsv482193 CNV Gain 20164927

Relevant External Links for C16orf58 Gene

HapMap Linkage Disequilibrium report
C16orf58

Disorders for C16orf58 Gene

No disorders were found for C16orf58 Gene.

No data available for UniProtKB/Swiss-Prot for C16orf58 Gene

Publications for C16orf58 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. ROOT UV-B SENSITIVE2 acts with ROOT UV-B SENSITIVE1 in a root ultraviolet B-sensing pathway. (PMID: 19515790) Leasure C.D. … He Z.H. (Plant Physiol. 2009) 3
  5. Defining the membrane proteome of NK cells. (PMID: 19946888) Ghosh D. … Wilkins J.A. (J Mass Spectrom 2010) 3

Products for C16orf58 Gene

  • antibodies-online peptides for C16orf58
  • antibodies-online antibodies for C16orf58
  • antibodies-online kits for C16orf58

Sources for C16orf58 Gene

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