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Aliases for C16orf52 Gene

Aliases for C16orf52 Gene

  • Chromosome 16 Open Reading Frame 52 2 3 5

External Ids for C16orf52 Gene

Previous GeneCards Identifiers for C16orf52 Gene

  • GC16P021928
  • GC16U900642
  • GC16P022021
  • GC16P020264

Summaries for C16orf52 Gene

GeneCards Summary for C16orf52 Gene

C16orf52 (Chromosome 16 Open Reading Frame 52) is a Protein Coding gene.

Additional gene information for C16orf52 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C16orf52 Gene

Genomics for C16orf52 Gene

Regulatory Elements for C16orf52 Gene

Enhancers for C16orf52 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16H022296 1.2 ENCODE 47.4 +290.1 290145 3 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC PPARGC1A ZFP41 NPIPB4 SMG1P3 NPIPB3 NPIPB5 SMG1P1 MFSD13B RRN3P1 C16orf52 SMG1P4 ENSG00000260635
GH16H022194 1.9 FANTOM5 Ensembl ENCODE dbSUPER 28.1 +188.1 188062 2 HDGF MLX ZFP64 ARID4B SIN3A DMAP1 YBX1 ZNF2 ZBTB7B YY1 SMG1P3 SMG1P1 NPIPB3 C16orf52 NPIPB4 SMG1P4 NPIPB5 POLR3E MFSD13B ENSG00000260635
GH16H021819 1.1 ENCODE 32.1 -187.4 -187379 1 HDGF ZFP64 SIN3A FEZF1 ZNF2 YY1 ZNF302 ZNF143 ZNF207 ZNF548 NPIPB4 NPIPB5 NPIPB3 SMG1P3 ENSG00000260635 SMG1P4 SMG1P1 ENSG00000260905 POLR3E MFSD13B
GH16H021934 1.3 Ensembl ENCODE 26.8 -72.2 -72206 1 HDGF FOXA2 GLI4 ZNF2 ZNF143 ATF7 KLF7 ZNF548 SP3 REST ENSG00000260306 NPIPB5 NPIPB4 ENSG00000260635 MFSD13B SMG1P4 SMG1P1 SMG1P3 C16orf52 NPIPB3
GH16H021624 1.8 FANTOM5 Ensembl ENCODE dbSUPER 12.2 -380.1 -380117 6 PKNOX1 FOXA2 ARID4B DMAP1 SLC30A9 ATF7 NFYC KAT8 NFIL3 MIER3 METTL9 IGSF6 C16orf52 ERI2 ENSG00000260905 ENSG00000260973 CRYM ENSG00000261596 GC16P021642
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C16orf52 on UCSC Golden Path with GeneCards custom track

Promoters for C16orf52 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000084421 762 2001 PKNOX1 ATF1 ARID4B SIN3A YY1 ZNF548 ATF7 SP3 ZHX2 MIER2

Genomic Location for C16orf52 Gene

Chromosome:
16
Start:
22,007,638 bp from pter
End:
22,087,534 bp from pter
Size:
79,897 bases
Orientation:
Plus strand

Genomic View for C16orf52 Gene

Genes around C16orf52 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C16orf52 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C16orf52 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf52 Gene

Proteins for C16orf52 Gene

  • Protein details for C16orf52 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NHV5-CP052_HUMAN
    Recommended name:
    Uncharacterized protein C16orf52
    Protein Accession:
    Q8NHV5
    Secondary Accessions:
    • H3BNM6

    Protein attributes for C16orf52 Gene

    Size:
    167 amino acids
    Molecular mass:
    18250 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C16orf52 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C16orf52 Gene

Post-translational modifications for C16orf52 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C16orf52 Gene

No data available for DME Specific Peptides for C16orf52 Gene

Domains & Families for C16orf52 Gene

Gene Families for C16orf52 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for C16orf52 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C16orf52: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C16orf52 Gene

Function for C16orf52 Gene

Phenotypes From GWAS Catalog for C16orf52 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C16orf52 Gene

Localization for C16orf52 Gene

Gene Ontology (GO) - Cellular Components for C16orf52 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C16orf52: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for C16orf52 Gene

Pathways & Interactions for C16orf52 Gene

SuperPathways for C16orf52 Gene

No Data Available

Interacting Proteins for C16orf52 Gene

Selected Interacting proteins: Q8NHV5-CP052_HUMAN for C16orf52 Gene via IID

Symbol External ID(s) Details
SGTB

Gene Ontology (GO) - Biological Process for C16orf52 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C16orf52 Gene

Drugs & Compounds for C16orf52 Gene

No Compound Related Data Available

Transcripts for C16orf52 Gene

mRNA/cDNA for C16orf52 Gene

(2) REFSEQ mRNAs :
(9) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C16orf52 Gene

Chromosome 16 open reading frame 52:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf52 Gene

No ASD Table

Relevant External Links for C16orf52 Gene

GeneLoc Exon Structure for
C16orf52
ECgene alternative splicing isoforms for
C16orf52

Expression for C16orf52 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C16orf52 Gene

NURSA nuclear receptor signaling pathways regulating expression of C16orf52 Gene:

C16orf52

SOURCE GeneReport for Unigene cluster for C16orf52 Gene:

Hs.498890
genes like me logo Genes that share expression patterns with C16orf52: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C16orf52 Gene

Orthologs for C16orf52 Gene

This gene was present in the common ancestor of animals.

Orthologs for C16orf52 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C16H16orf52 33
  • 100 (n)
dog
(Canis familiaris)
Mammalia C16orf52 34
  • 100 (a)
OneToOne
C6H16orf52 33
  • 98.2 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia C16orf52 34
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C16orf52 34
  • 99 (a)
OneToOne
C25H16orf52 33
  • 98 (n)
oppossum
(Monodelphis domestica)
Mammalia C16orf52 34
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia BC030336 33 16 34
  • 97.01 (n)
rat
(Rattus norvegicus)
Mammalia LOC102547219 33
  • 96.18 (n)
chicken
(Gallus gallus)
Aves C16orf52 34
  • 99 (a)
OneToOne
C14H16ORF52 33
  • 90.02 (n)
lizard
(Anolis carolinensis)
Reptilia C16orf52 34
  • 98 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c16orf52 33
  • 86.83 (n)
zebrafish
(Danio rerio)
Actinopterygii C12H16orf52 34
  • 90 (a)
OneToOne
LOC100535551 33
  • 82.04 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG14182 33 34
  • 55.42 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012207 33
  • 54.14 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6797 34
  • 48 (a)
OneToOne
Species where no ortholog for C16orf52 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C16orf52 Gene

ENSEMBL:
Gene Tree for C16orf52 (if available)
TreeFam:
Gene Tree for C16orf52 (if available)

Paralogs for C16orf52 Gene

Pseudogenes.org Pseudogenes for C16orf52 Gene

genes like me logo Genes that share paralogs with C16orf52: view

No data available for Paralogs for C16orf52 Gene

Variants for C16orf52 Gene

Sequence variations from dbSNP and Humsavar for C16orf52 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000026454 -- 22,010,444(+) TTCAC(G/T)TACTT intron-variant
rs1000029079 -- 22,025,957(+) GTAAC(C/T)ATTTG intron-variant
rs1000032265 -- 22,065,155(+) GAGGG(A/C)AGTGT intron-variant
rs1000049504 -- 22,025,236(+) GTATA(C/T)AAAAC intron-variant
rs1000070750 -- 22,018,058(+) TAGCA(A/G)AAGGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C16orf52 Gene

Variant ID Type Subtype PubMed ID
dgv3n1 OTHER inversion 15895083
dgv47n16 OTHER inversion 17901297
esv2672814 CNV deletion 23128226
esv3368991 OTHER inversion 20981092
esv3553223 CNV deletion 23714750
esv3638193 CNV gain 21293372
esv3638194 CNV loss 21293372
esv3638195 CNV gain 21293372
esv3638196 CNV gain 21293372
esv998989 OTHER inversion 20482838
nsv1069929 CNV deletion 25765185
nsv1070758 CNV deletion 25765185
nsv1077770 OTHER inversion 25765185
nsv1140248 OTHER inversion 24896259
nsv428322 CNV gain 18775914
nsv469628 CNV gain 16826518
nsv499139 OTHER inversion 21111241
nsv7280 OTHER inversion 18451855

Variation tolerance for C16orf52 Gene

Gene Damage Index Score: 6.38; 77.00% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C16orf52 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C16orf52

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C16orf52 Gene

Disorders for C16orf52 Gene

Relevant External Links for C16orf52

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C16orf52

No disorders were found for C16orf52 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C16orf52 Gene

Publications for C16orf52 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  2. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 3 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 60

Products for C16orf52 Gene

Sources for C16orf52 Gene

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