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Aliases for C16orf46 Gene

Aliases for C16orf46 Gene

  • Chromosome 16 Open Reading Frame 46 2 3

External Ids for C16orf46 Gene

Previous GeneCards Identifiers for C16orf46 Gene

  • GC16M079653
  • GC16M081087
  • GC16M066843

Summaries for C16orf46 Gene

GeneCards Summary for C16orf46 Gene

C16orf46 (Chromosome 16 Open Reading Frame 46) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C16orf46 Gene

Genomics for C16orf46 Gene

Regulatory Elements for C16orf46 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C16orf46 Gene

81,053,497 bp from pter
81,077,267 bp from pter
23,771 bases
Minus strand

Genomic View for C16orf46 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C16orf46 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf46 Gene

Proteins for C16orf46 Gene

  • Protein details for C16orf46 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C16orf46
    Protein Accession:
    Secondary Accessions:
    • Q96MA7

    Protein attributes for C16orf46 Gene

    395 amino acids
    Molecular mass:
    43418 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C16orf46 Gene


neXtProt entry for C16orf46 Gene

Proteomics data for C16orf46 Gene at MOPED

Post-translational modifications for C16orf46 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C16orf46 Gene

No data available for DME Specific Peptides for C16orf46 Gene

Domains for C16orf46 Gene

Protein Domains for C16orf46 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C16orf46: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C16orf46 Gene

Function for C16orf46 Gene

Animal Model Products

CRISPR Products

miRNA for C16orf46 Gene

miRTarBase miRNAs that target C16orf46

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C16orf46

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C16orf46 Gene

Localization for C16orf46 Gene

Subcellular locations from

Jensen Localization Image for C16orf46 Gene COMPARTMENTS Subcellular localization image for C16orf46 gene
Compartment Confidence
cytosol 4
nucleus 4

Gene Ontology (GO) - Cellular Components for C16orf46 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with C16orf46: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C16orf46 Gene

Pathways for C16orf46 Gene

SuperPathways for C16orf46 Gene

No Data Available

Interacting Proteins for C16orf46 Gene

Gene Ontology (GO) - Biological Process for C16orf46 Gene


No data available for Pathways by source for C16orf46 Gene

Transcripts for C16orf46 Gene

Unigene Clusters for C16orf46 Gene

Chromosome 16 open reading frame 46:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C16orf46

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf46 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5
SP1: -
SP3: - - - -

Relevant External Links for C16orf46 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C16orf46 Gene

mRNA expression in normal human tissues for C16orf46 Gene

Protein differential expression in normal tissues for C16orf46 Gene

This gene is overexpressed in Monocytes (55.3) and Lung (7.3).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C16orf46 Gene

SOURCE GeneReport for Unigene cluster for C16orf46 Gene Hs.658684

genes like me logo Genes that share expressions with C16orf46: view

Expression partners for C16orf46 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C16orf46 Gene

Orthologs for C16orf46 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C16orf46 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C18H16orf46 35
  • 79.09 (n)
  • 66.07 (a)
C16orf46 36
  • 65 (a)
(Canis familiaris)
Mammalia C5H16orf46 35
  • 82.05 (n)
  • 71.03 (a)
C16orf46 36
  • 71 (a)
(Mus musculus)
Mammalia 1700030J22Rik 35
  • 69.29 (n)
  • 56.6 (a)
1700030J22Rik 16
1700030J22Rik 36
  • 54 (a)
(Pan troglodytes)
Mammalia C16H16orf46 35
  • 98.82 (n)
  • 97.97 (a)
C16orf46 36
  • 96 (a)
(Rattus norvegicus)
Mammalia LOC687399 35
  • 68.45 (n)
  • 54.34 (a)
(Monodelphis domestica)
Mammalia C16orf46 36
  • 39 (a)
(Ornithorhynchus anatinus)
Mammalia C16orf46 36
  • 37 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100487055 35
  • 43.34 (n)
  • 30.65 (a)
Species with no ortholog for C16orf46:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C16orf46 Gene

Gene Tree for C16orf46 (if available)
Gene Tree for C16orf46 (if available)

Paralogs for C16orf46 Gene

No data available for Paralogs for C16orf46 Gene

Variants for C16orf46 Gene

Sequence variations from dbSNP and Humsavar for C16orf46 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs754427 -- 81,062,454(+) AGCAA(C/T)AGTAT intron-variant
rs754428 -- 81,062,504(+) TCAAA(G/T)GCACA intron-variant
rs754429 -- 81,062,574(+) GATTT(C/T)GGGCA intron-variant
rs804884 -- 81,061,155(+) ACCGC(A/G)ACCGC intron-variant, utr-variant-3-prime
rs804885 -- 81,061,758(+) ATGGA(C/T)AGCCC synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for C16orf46 Gene

Variant ID Type Subtype PubMed ID
nsv1897 CNV Loss 18451855
esv2422360 CNV Duplication 17116639
dgv356n27 CNV Loss 19166990
esv2751615 CNV Gain 17911159

Relevant External Links for C16orf46 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C16orf46 Gene

Disorders for C16orf46 Gene

Relevant External Links for C16orf46

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for C16orf46 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C16orf46 Gene

Publications for C16orf46 Gene

  1. Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PMID: 18951430) Anney R.J. … Gill M. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008) 3 48
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for C16orf46 Gene

Sources for C16orf46 Gene

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