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Aliases for C16orf45 Gene

Aliases for C16orf45 Gene

  • Chromosome 16 Open Reading Frame 45 2 3

External Ids for C16orf45 Gene

Previous GeneCards Identifiers for C16orf45 Gene

  • GC16P015436
  • GC16P014921

Summaries for C16orf45 Gene

GeneCards Summary for C16orf45 Gene

C16orf45 (Chromosome 16 Open Reading Frame 45) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C16orf45 Gene

Genomics for C16orf45 Gene

Regulatory Elements for C16orf45 Gene

Genomic Location for C16orf45 Gene

15,434,295 bp from pter
15,625,028 bp from pter
190,734 bases
Plus strand

Genomic View for C16orf45 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C16orf45 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C16orf45 Gene

Proteins for C16orf45 Gene

  • Protein details for C16orf45 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C16orf45
    Protein Accession:
    Secondary Accessions:
    • O00223
    • O75769
    • Q8IZ36
    • Q96H25

    Protein attributes for C16orf45 Gene

    204 amino acids
    Molecular mass:
    23732 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAC31663.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for C16orf45 Gene


neXtProt entry for C16orf45 Gene

Proteomics data for C16orf45 Gene at MOPED

Post-translational modifications for C16orf45 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C16orf45 Gene

Domains for C16orf45 Gene

Protein Domains for C16orf45 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C16orf45: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C16orf45 Gene

Function for C16orf45 Gene

Gene Ontology (GO) - Molecular Function for C16orf45 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C16orf45: view

Phenotypes for C16orf45 Gene

GenomeRNAi human phenotypes for C16orf45:
genes like me logo Genes that share phenotypes with C16orf45: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C16orf45 Gene

Localization for C16orf45 Gene

Subcellular locations from

Jensen Localization Image for C16orf45 Gene COMPARTMENTS Subcellular localization image for C16orf45 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C16orf45 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015630 microtubule cytoskeleton IEA --
genes like me logo Genes that share ontologies with C16orf45: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C16orf45 Gene

Pathways for C16orf45 Gene

SuperPathways for C16orf45 Gene

No Data Available

Interacting Proteins for C16orf45 Gene

Gene Ontology (GO) - Biological Process for C16orf45 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007026 negative regulation of microtubule depolymerization IEA --
GO:0021822 negative regulation of cell motility involved in cerebral cortex radial glia guided migration IEA --
genes like me logo Genes that share ontologies with C16orf45: view

No data available for Pathways by source for C16orf45 Gene

Transcripts for C16orf45 Gene

Unigene Clusters for C16orf45 Gene

Chromosome 16 open reading frame 45:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C16orf45 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e ^ 8 ^ 9
SP1: - - -
SP2: - -
SP3: - - - -

Relevant External Links for C16orf45 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C16orf45 Gene

mRNA expression in normal human tissues for C16orf45 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for C16orf45 Gene

SOURCE GeneReport for Unigene cluster for C16orf45 Gene Hs.401798

genes like me logo Genes that share expressions with C16orf45: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C16orf45 Gene

Orthologs for C16orf45 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C16orf45 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C16H16orf45 35
  • 99.84 (n)
  • 99.51 (a)
C16ORF45 36
  • 100 (a)
(Bos Taurus)
Mammalia C25H16orf45 35
  • 93.65 (n)
  • 96.43 (a)
MGC140681 36
  • 88 (a)
(Canis familiaris)
Mammalia C16orf45 36
  • 97 (a)
C6H16orf45 35
  • 92.48 (n)
  • 97.06 (a)
(Mus musculus)
Mammalia 2900011O08Rik 35
  • 91.46 (n)
  • 95.57 (a)
2900011O08Rik 16
2900011O08Rik 36
  • 96 (a)
(Monodelphis domestica)
Mammalia C16orf45 36
  • 95 (a)
(Ornithorhynchus anatinus)
Mammalia C16orf45 36
  • 86 (a)
(Rattus norvegicus)
Mammalia RGD1305733 35
  • 91.13 (n)
  • 96.06 (a)
(Gallus gallus)
Aves C16ORF45 35
  • 77.12 (n)
  • 85.29 (a)
C16ORF45 36
  • 85 (a)
(Anolis carolinensis)
Reptilia C16orf45 36
  • 61 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c16orf45 35
  • 73.1 (n)
  • 74.26 (a)
(Danio rerio)
Actinopterygii C6H16orf45 36
  • 60 (a)
zgc:114175 35
  • 65.58 (n)
  • 60.87 (a)
Species with no ortholog for C16orf45:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C16orf45 Gene

Gene Tree for C16orf45 (if available)
Gene Tree for C16orf45 (if available)

Paralogs for C16orf45 Gene

No data available for Paralogs for C16orf45 Gene

Variants for C16orf45 Gene

Sequence variations from dbSNP and Humsavar for C16orf45 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs34792 -- 15,493,640(-) AACGG(C/G)TCCAG intron-variant
rs34793 -- 15,491,779(-) agctg(A/C)cactg intron-variant
rs40606 -- 15,435,096(+) GGATC(C/T)TCTCT intron-variant
rs111671 -- 15,435,454(+) CGAAG(C/G)ATTTT intron-variant
rs115452 -- 15,465,596(-) gcagg(C/T)ggatc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C16orf45 Gene

Variant ID Type Subtype PubMed ID
nsv435664 CNV Deletion 17901297
esv2714015 CNV Deletion 23290073
nsv905386 CNV Gain 21882294
dgv2610n71 CNV Gain 21882294
nsv457428 CNV Gain 19166990
nsv833147 CNV Loss 17160897
nsv827568 CNV Loss 20364138
esv2671884 CNV Deletion 23128226
nsv510677 CNV Loss 20534489
esv2714016 CNV Deletion 23290073
esv2678976 CNV Deletion 23128226

Relevant External Links for C16orf45 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C16orf45 Gene

Disorders for C16orf45 Gene

Relevant External Links for C16orf45

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with C16orf45: view

No data available for UniProtKB/Swiss-Prot for C16orf45 Gene

Publications for C16orf45 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus B.J. … Adams M.D. (Genomics 1999) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3

Products for C16orf45 Gene

Sources for C16orf45 Gene

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