C16orf3 Gene
protein-coding GIFtS: 38
GCID: GC16M090095
|
|
chromosome 16 open reading frame 3
| |
Aliases
for C16orf3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 16 Open Reading Frame 31 2 | | Uncharacterized Protein C16orf32 | | EID15 |
Export aliases for C16orf3 gene to outside databasesPrevious GC identifers: GC16M081415 GC16M091082 GC16M089796 GC16M089837 GC16M088622 GC16M075786 |
Summaries
for C16orf3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C16orf3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010542.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C16orf3 gene promoter:
NF-1/L NF-1 Pax-5 HOXA3 AP-1 LCR-F1 GATA-1 c-Ets-1 GATA-2 Evi-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C16orf3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C16orf3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q24.3 Ensembl cytogenetic band: 16q24.3 HGNC cytogenetic band: 16q24.3C16orf3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M090095: view genomic region
(about GC identifiers)
Start:
|
90,095,316 bp from pter |
End:
|
90,096,309 bp from pter |
Size:
|
994 bases |
Orientation:
|
minus strand |
|
Proteins
for C16orf3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CP003_HUMAN, O95177 (See
protein sequence)Recommended Name: Uncharacterized protein C16orf3 Size: 125 amino acids; 12619 Da
Secondary accessions: O95176 Q52LX9Explore the universe of human proteins at neXtProt for C16orf3: NX_O95177
C16orf3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001205.3
ENSEMBL proteins: ENSP00000386218
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005575 | cellular_component |
ND | -- |
C16orf3 for ontologies About GeneDecksing
C16orf3 Antibody Products:
Assay Products for C16orf3: |
Protein
Domains /
Families
for C16orf3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: O95177 |
Function
for C16orf3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
Genatlas biochemistry entry for C16orf3:chromosome 16 open reading frame 3,nested in the second intron of GAS11 gene, in opposite orientation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf3
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C16orf3 (NM_001214) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C16orf3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf3 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
C16orf3 for ontologies About GeneDecksing
|
Pathways & Interactions
for C16orf3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C16orf3
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
C16orf3 for ontologies About GeneDecksing
|
Drugs & Compounds
for C16orf3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C16orf3
Search CenterWatch for drugs/clinical trials and news about C16orf3 / CP003
|
Transcripts
for C16orf3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C16orf3 gene: NM_001214.3 Unigene Cluster for C16orf3: Chromosome 16 open reading frame 3 Hs.633032 [show with all ESTs]Unigene Representative Sequence: AF0500811 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000408886(uc002fqk.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf3
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C16orf3 (NM_001214) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C16orf3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf3 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C16orf3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C16orf3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C16orf3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C16orf3 |
Additional cDNA sequence: AF050080.1 AF050081.1 BC093751.1 BC104849.1 1 DOTS entry: DT.40108502 5 AceView cDNA sequences: AF050080 NM_001214 AF050081 T79834 T87378
GeneLoc Exon Structure
|
Expression
for C16orf3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C16orf3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See C16orf3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C16orf3
SOURCE GeneReport for Unigene cluster: Hs.633032
SABiosciences Custom PCR Arrays for C16orf3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C16orf3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C16orf3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C16orf3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C16orf3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf3 |
Orthologs
for C16orf3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for C16orf3 (if available)
TreeFam Gene Tree for C16orf3 (if available) |
Paralogs
for C16orf3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C16orf3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: CP003_HUMAN, O95177Polymorphism: There seems to be two alleles of this protein
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C16orf3 (90095316 - 90096309 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for C16orf3
1 CNV: 0200 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C16orf3 |
|
Disorders
/ Diseases
for C16orf3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C16orf3 for disorders About GeneDecksing
OMIM gene information: 605179
OMIM disorders: --
1  disease for C16orf3: About MalaCardsbreast cancer
Export disorders for C16orf3 gene to outside databases
|
Publications
for C16orf3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C16orf3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C16orf3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization and screening for mutations of the growth arrest- specific 11 (GAS11) and C16orf3 genes at 16q24.3 in breast cancer. (PubMed id 9790751)1, 2, 3 Whitmore S.A.... Callen D.F. (1998)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for C16orf3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C16orf3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C16orf3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C16orf3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C16orf3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C16orf3 gene:
Search GeneIP for patents involving C16orf3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C16orf3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C16orf3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C16orf3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C16orf3 | | | OriGene Protein Over-expression Lysate for C16orf3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C16orf3 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for C16orf3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C16orf3 | | OriGene Custom Protein Services for C16orf3 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C16orf3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C16orf3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C16orf3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C16orf3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C16orf3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C16orf3 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for C16orf3 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | C16orf3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf3 |
|  |  |  | | | | Search ThermoFisher Antibodies for C16orf3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf3 |
|
|
|
|
