C16orf11 Gene
protein-coding GIFtS: 36
GCID: GC16P000610
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chromosome 16 open reading frame 11
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Aliases
for C16orf11 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 16 Open Reading Frame 111 2 | | Uncharacterized Protein RJD12 3 | | Uncharacterized Protein C16orf112 |
Export aliases for C16orf11 gene to outside databasesPrevious GC identifers: GC16U990161 GC16P000552 |
Summaries
for C16orf11 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C16orf11 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C16orf11 gene promoter:
ER-alpha E2F-4 E2F-3a E2F-5 E2F-2 AREB6 IRF-2 E2F E2F-1 c-Myb
Other transcription factors
Search SABiosciences Chromatin IP Primers for C16orf11
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C16orf11 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3C16orf11 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P000610: view genomic region
(about GC identifiers)
Start:
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610,422 bp from pter |
End:
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615,529 bp from pter |
Size:
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5,108 bases |
Orientation:
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plus strand |
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Proteins
for C16orf11 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CP011_HUMAN, P0CG20 (See
protein sequence)Recommended Name: Uncharacterized protein C16orf11 Size: 571 amino acids; 59354 Da
Sequence caution: Sequence=AAK61234.1; Type=Erroneous gene model prediction;
Secondary accessions: B8ZZ27 Q8N233 Q96AX3 Q96S23Explore the universe of human proteins at neXtProt for C16orf11: NX_P0CG20
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P0CG20
C16orf11 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_660313.1
ENSEMBL proteins: ENSP00000386499
Human Recombinant Protein Products:
C16orf11 Antibody Products:
Assay Products for C16orf11: |
Protein
Domains /
Families
for C16orf11 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: P0CG20 |
Function
for C16orf11 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf11
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf11
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for C16orf11 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf11 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf11 |
2 GenomeRNAi human phenotypes for C16orf11:
|
Pathways & Interactions
for C16orf11 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C16orf11
|
Drugs & Compounds
for C16orf11 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C16orf11
Search CenterWatch for drugs/clinical trials and news about C16orf11 / CP011
|
Transcripts
for C16orf11 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C16orf11 gene: NM_145270.2 Unigene Cluster for C16orf11: Chromosome 16 open reading frame 11 Hs.632220 [show with all ESTs]Unigene Representative Sequence: BC0166131 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000409413(uc002chk.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf11
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf11
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C16orf11 (NM_145270) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C16orf11 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf11 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C16orf11
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C16orf11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C16orf11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C16orf11 |
Additional cDNA sequence: BC016613.1 1 DOTS entry: DT.401668 7 AceView cDNA sequences: BC016613 NM_145270 H20980 BX281088 H50241 AA757196 BE784253
GeneLoc Exon Structure
|
Expression
for C16orf11 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C16orf11 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGGGCCCTG
About this image
See C16orf11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C16orf11
SOURCE GeneReport for Unigene cluster: Hs.632220
SABiosciences Custom PCR Arrays for C16orf11
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C16orf11
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C16orf11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C16orf11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C16orf11 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf11 |
Orthologs
for C16orf11 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C16orf11 gene from 4/10 species (see all 10) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
LOC4163881 |
uncharacterized LOC416388 |
57.98(n)
46.55(a) |
|
416388 XM_414703.3 XP_414703.3 |
lizard
(Anolis carolinensis) |
Reptilia |
C16orf116 |
-- |
40(a) |
1 ↔ 1 |
GL344114.1(22955-27362) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.136812 |
Xenopus laevis transcribed sequence with weak similarity more |
75.89(n) |
|
BJ033142.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
si:ch211-248l17.36 |
si:ch211-248l17.3 |
27(a) |
1 ↔ 1 |
24(39499383-39515607) |
Species with no ortholog for C16orf11
ENSEMBL Gene Tree for C16orf11 (if available)
TreeFam Gene Tree for C16orf11 (if available) |
Paralogs
for C16orf11 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C16orf11 gene
- ZNF7502
C16orf11 for paralogs About GeneDecksing
|
Genomic Variants
for C16orf11 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C16orf11 (610422 - 615529 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for C16orf11
7 CNVs: 72397 3987 4913 29984 5329 29983 4914 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C16orf11 |
|
Disorders
/ Diseases
for C16orf11 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C16orf11 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C16orf11 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C16orf11) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)2 Daniels R.J....Higgs D.R. (2001)
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External Searches for C16orf11 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C16orf11 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C16orf11 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C16orf11 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C16orf11 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C16orf11 gene:
Search GeneIP for patents involving C16orf11
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C16orf11 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C16orf11 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C16orf11 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C16orf11 | | | OriGene Protein Over-expression Lysate for C16orf11 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C16orf11 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf11 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C16orf11 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | C16orf11 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C16orf11 |
|  |  |  | | | | Search ThermoFisher Antibodies for C16orf11 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C16orf11 |
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