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Aliases for C15orf65 Gene

Aliases for C15orf65 Gene

  • Chromosome 15 Open Reading Frame 65 2 3 5

External Ids for C15orf65 Gene

Previous GeneCards Identifiers for C15orf65 Gene

  • GC15P055702

Summaries for C15orf65 Gene

GeneCards Summary for C15orf65 Gene

C15orf65 (Chromosome 15 Open Reading Frame 65) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C15orf65 Gene

Genomics for C15orf65 Gene

Regulatory Elements for C15orf65 Gene

Enhancers for C15orf65 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F055396 0.4 ENCODE 10.8 -11.4 -11417 0.9 TBP HDAC1 CBX3 ARNT NFRKB CHAMP1 GTF3C2 GATA2 ZBTB2 NCOA1 C15orf65 PIGB DYX1C1 GC15M055985 GC15M055482
GH15F055401 0.4 ENCODE 10.7 -3.0 -2966 7.7 HDGF PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF207 RSL24D1 PYGO1 DYX1C1 C15orf65 PIGB CCPG1 MIR628 GC15M055985
GH15F055497 0.2 ENCODE 10.4 +89.9 89910 1.4 ARID4B SIN3A DMAP1 ZNF48 ZNF2 YY1 GTF3C2 ZNF143 MXD4 ZNF518A RSL24D1 PYGO1 C15orf65 PIGB DYX1C1 DYX1C1-CCPG1 LOC100420711
GH15F055394 1.1 Ensembl ENCODE 9.8 -13.7 -13725 1.6 CEBPB TRIM24 ZNF843 C15orf65 DYX1C1 PIGB CCPG1 GC15M055985 GC15M055482
GH15F055388 0.5 ENCODE 9.8 -19.3 -19257 1.3 JUND JUN CEBPB IRF1 FOS EP300 TCF7L2 C15orf65 PIGB GC15M055985 GC15M055482
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C15orf65 on UCSC Golden Path with GeneCards custom track

Promoters for C15orf65 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000408268 -325 2400 HDGF CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143 KLF13

Genomic Location for C15orf65 Gene

Chromosome:
15
Start:
55,408,525 bp from pter
End:
55,418,764 bp from pter
Size:
10,240 bases
Orientation:
Plus strand

Genomic View for C15orf65 Gene

Genes around C15orf65 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C15orf65 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C15orf65 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C15orf65 Gene

Proteins for C15orf65 Gene

  • Protein details for C15orf65 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H3BRN8-CO065_HUMAN
    Recommended name:
    Uncharacterized protein C15orf65
    Protein Accession:
    H3BRN8

    Protein attributes for C15orf65 Gene

    Size:
    121 amino acids
    Molecular mass:
    13763 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C15orf65 Gene

Post-translational modifications for C15orf65 Gene

No Post-translational modifications

Other Protein References for C15orf65 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C15orf65 Gene

Domains & Families for C15orf65 Gene

Protein Domains for C15orf65 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C15orf65: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C15orf65 Gene

Function for C15orf65 Gene

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C15orf65 Gene

Localization for C15orf65 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C15orf65 Gene

Pathways & Interactions for C15orf65 Gene

SuperPathways for C15orf65 Gene

No Data Available

Interacting Proteins for C15orf65 Gene

Gene Ontology (GO) - Biological Process for C15orf65 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C15orf65 Gene

Transcripts for C15orf65 Gene

mRNA/cDNA for C15orf65 Gene

(1) REFSEQ mRNAs :
(10) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for C15orf65 Gene

No ASD Table

Relevant External Links for C15orf65 Gene

GeneLoc Exon Structure for
C15orf65
ECgene alternative splicing isoforms for
C15orf65

Expression for C15orf65 Gene

mRNA expression in normal human tissues for C15orf65 Gene

NURSA nuclear receptor signaling pathways regulating expression of C15orf65 Gene:

C15orf65
genes like me logo Genes that share expression patterns with C15orf65: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C15orf65 Gene

Orthologs for C15orf65 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for C15orf65 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100611501 34
  • 99.72 (n)
mouse
(Mus musculus)
Mammalia Ccpg1os 34 16
  • 74.29 (n)
Gm5918 35
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC691849 34
  • 73.73 (n)
Species where no ortholog for C15orf65 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C15orf65 Gene

ENSEMBL:
Gene Tree for C15orf65 (if available)
TreeFam:
Gene Tree for C15orf65 (if available)

Paralogs for C15orf65 Gene

No data available for Paralogs for C15orf65 Gene

Variants for C15orf65 Gene

Sequence variations from dbSNP and Humsavar for C15orf65 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs10549986 -- 55,412,118(+) AAAAA(-/A)TTGAT intron-variant
rs10615674 -- 55,418,940(+) TTTTG(-/AG)TGAGT intron-variant
rs10616796 -- 55,418,693(+) TTAAA(-/TAAA)GTATT intron-variant, utr-variant-3-prime
rs111307136 -- 55,416,268(+) AGCTA(A/T)TTTTT intron-variant
rs111400388 -- 55,414,301(+) GCCTC(A/C)CGGGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C15orf65 Gene

Variant ID Type Subtype PubMed ID
esv2761899 CNV gain+loss 21179565
esv3373880 CNV insertion 20981092
esv3569598 CNV gain 25503493
esv3636560 CNV loss 21293372
nsv1043789 CNV gain 25217958
nsv520799 CNV loss 19592680
nsv569523 CNV gain 21841781

Variation tolerance for C15orf65 Gene

Gene Damage Index Score: 6.97; 79.91% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C15orf65 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C15orf65

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C15orf65 Gene

Disorders for C15orf65 Gene

Relevant External Links for C15orf65

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C15orf65

No disorders were found for C15orf65 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C15orf65 Gene

Publications for C15orf65 Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  3. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 4 64

Products for C15orf65 Gene

Sources for C15orf65 Gene

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