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Aliases for C15orf62 Gene

Aliases for C15orf62 Gene

  • Chromosome 15 Open Reading Frame 62 2 3 5

External Ids for C15orf62 Gene

Previous GeneCards Identifiers for C15orf62 Gene

  • GC15P038853
  • GC15P041062
  • GC15P017910

Summaries for C15orf62 Gene

GeneCards Summary for C15orf62 Gene

C15orf62 (Chromosome 15 Open Reading Frame 62) is a Protein Coding gene. GO annotations related to this gene include GTP-Rho binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C15orf62 Gene

Genomics for C15orf62 Gene

Regulatory Elements for C15orf62 Gene

Enhancers for C15orf62 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C15orf62 on UCSC Golden Path with GeneCards custom track

Promoters for C15orf62 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C15orf62 on UCSC Golden Path with GeneCards custom track

Genomic Location for C15orf62 Gene

Chromosome:
15
Start:
40,769,961 bp from pter
End:
40,772,449 bp from pter
Size:
2,489 bases
Orientation:
Plus strand

Genomic View for C15orf62 Gene

Genes around C15orf62 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C15orf62 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C15orf62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C15orf62 Gene

Proteins for C15orf62 Gene

  • Protein details for C15orf62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8K5M9-CO062_HUMAN
    Recommended name:
    Uncharacterized protein C15orf62, mitochondrial
    Protein Accession:
    A8K5M9
    Secondary Accessions:
    • A6NK01

    Protein attributes for C15orf62 Gene

    Size:
    175 amino acids
    Molecular mass:
    19679 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C15orf62 Gene

Proteomics data for C15orf62 Gene at MOPED

Post-translational modifications for C15orf62 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C15orf62 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C15orf62 Gene

Domains & Families for C15orf62 Gene

Protein Domains for C15orf62 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C15orf62: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C15orf62 Gene

Function for C15orf62 Gene

Gene Ontology (GO) - Molecular Function for C15orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005096 GTPase activator activity IBA --
genes like me logo Genes that share ontologies with C15orf62: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C15orf62 Gene

Localization for C15orf62 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C15orf62 Gene

Mitochondrion.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C15orf62 Gene COMPARTMENTS Subcellular localization image for C15orf62 gene
Compartment Confidence
mitochondrion 4
plasma membrane 3
nucleus 2
cytosol 1

Gene Ontology (GO) - Cellular Components for C15orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with C15orf62: view

Pathways & Interactions for C15orf62 Gene

SuperPathways for C15orf62 Gene

No Data Available

Interacting Proteins for C15orf62 Gene

Gene Ontology (GO) - Biological Process for C15orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030838 positive regulation of actin filament polymerization IBA --
GO:0031274 positive regulation of pseudopodium assembly IBA --
GO:0043547 positive regulation of GTPase activity IBA --
genes like me logo Genes that share ontologies with C15orf62: view

No data available for Pathways by source and SIGNOR curated interactions for C15orf62 Gene

Drugs & Compounds for C15orf62 Gene

No Compound Related Data Available

Transcripts for C15orf62 Gene

mRNA/cDNA for C15orf62 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C15orf62 Gene

Chromosome 15 open reading frame 62:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C15orf62 Gene

No ASD Table

Relevant External Links for C15orf62 Gene

GeneLoc Exon Structure for
C15orf62
ECgene alternative splicing isoforms for
C15orf62

Expression for C15orf62 Gene

mRNA expression in normal human tissues for C15orf62 Gene

mRNA expression in normal human tissues for C15orf62 Gene

Protein differential expression in normal tissues from HIPED for C15orf62 Gene

This gene is overexpressed in Plasma (47.4) and Heart (21.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C15orf62 Gene



SOURCE GeneReport for Unigene cluster for C15orf62 Gene Hs.631715

genes like me logo Genes that share expression patterns with C15orf62: view

Protein tissue co-expression partners for C15orf62 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C15orf62 Gene

Orthologs for C15orf62 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C15orf62 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C10H15orf62 35
  • 86.27 (n)
  • 88.24 (a)
C15orf62 36
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C30H15orf62 35
  • 88.95 (n)
  • 89.14 (a)
C15orf62 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm14137 35
  • 85.33 (n)
  • 86.29 (a)
Gm14137 16
Gm14137 36
  • 83 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C15H15orf62 35
  • 99.62 (n)
  • 100 (a)
rat
(Rattus norvegicus)
Mammalia LOC691418 35
  • 84.95 (n)
  • 86.29 (a)
oppossum
(Monodelphis domestica)
Mammalia C15orf62 36
  • 80 (a)
OneToOne
chicken
(Gallus gallus)
Aves C5H15ORF62 35
  • 54.17 (n)
  • 45 (a)
C15orf62 36
  • 38 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C15orf62 36
  • 33 (a)
OneToOne
Species with no ortholog for C15orf62:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C15orf62 Gene

ENSEMBL:
Gene Tree for C15orf62 (if available)
TreeFam:
Gene Tree for C15orf62 (if available)

Paralogs for C15orf62 Gene

No data available for Paralogs for C15orf62 Gene

Variants for C15orf62 Gene

Structural Variations from Database of Genomic Variants (DGV) for C15orf62 Gene

Variant ID Type Subtype PubMed ID
nsv904101 CNV Loss 21882294
nsv904102 CNV Loss 21882294
nsv827306 CNV Loss 20364138

Variation tolerance for C15orf62 Gene

Gene Damage Index Score: 2.09; 38.25% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Relevant External Links for C15orf62 Gene

Disorders for C15orf62 Gene

Relevant External Links for C15orf62

Genetic Association Database (GAD)
C15orf62
Human Genome Epidemiology (HuGE) Navigator
C15orf62
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C15orf62

No disorders were found for C15orf62 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C15orf62 Gene

Publications for C15orf62 Gene

  1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48 67
  2. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for C15orf62 Gene

Sources for C15orf62 Gene

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