Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C15orf61 Gene

Aliases for C15orf61 Gene

  • Chromosome 15 Open Reading Frame 61 2 3 5

External Ids for C15orf61 Gene

Previous GeneCards Identifiers for C15orf61 Gene

  • GC15P065600
  • GC15P067813
  • GC15P044649

Summaries for C15orf61 Gene

GeneCards Summary for C15orf61 Gene

C15orf61 (Chromosome 15 Open Reading Frame 61) is a Protein Coding gene.

Additional gene information for C15orf61 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C15orf61 Gene

Genomics for C15orf61 Gene

Regulatory Elements for C15orf61 Gene

Enhancers for C15orf61 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15H067548 0.8 ENCODE 11.6 +28.0 27980 0 ZSCAN5A ZBTB21 FEZF1 ZNF384 ZIC2 ZNF2 ZEB1 POLR2A ZNF600 ZEB2 C15orf61 LOC101929076 SKOR1 RNU6-1 MAP2K5 GC15P068073
GH15H067967 1.3 FANTOM5 Ensembl ENCODE 1.7 +447.4 447375 1 PKNOX1 KLF1 BMI1 RAD21 ZFHX2 EGR1 POLR2A PATZ1 ZNF600 EGR2 PIAS1 RNU6-1 LOC101929076 SKOR1 ENSG00000260657 C15orf61 GC15M067974 GC15M067840
GH15H067520 1.1 ENCODE 0.7 +0.7 689 3 HDGF PKNOX1 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B IQCH-AS1 MAP2K5 SKOR1 C15orf61
GH15H067504 0.7 ENCODE 0.4 -16.0 -16031 0 ZBTB21 ZSCAN4 ZNF10 CEBPB ZEB2 CEBPG ZNF2 BCL11B ZFP69B ZNF169 MAP2K5 SKOR1 LOC101929076 RNU6-1 GC15P068905 C15orf61
GH15H067510 0.6 ENCODE 0.4 -10.0 -10021 1 HDAC1 ZNF362 E2F5 ZNF384 TFDP1 JUND ZNF766 GATA2 FOS IQCH-AS1 MAP2K5 GC15P068905 C15orf61
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C15orf61 on UCSC Golden Path with GeneCards custom track

Promoters for C15orf61 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000078375 532 2401 HDGF PKNOX1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1

Genomic Location for C15orf61 Gene

Chromosome:
15
Start:
67,521,068 bp from pter
End:
67,530,143 bp from pter
Size:
9,076 bases
Orientation:
Plus strand

Genomic View for C15orf61 Gene

Genes around C15orf61 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C15orf61 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C15orf61 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C15orf61 Gene

Proteins for C15orf61 Gene

  • Protein details for C15orf61 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NNL5-CO061_HUMAN
    Recommended name:
    Uncharacterized protein C15orf61
    Protein Accession:
    A6NNL5
    Secondary Accessions:
    • B4DFB2

    Protein attributes for C15orf61 Gene

    Size:
    157 amino acids
    Molecular mass:
    18091 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C15orf61 Gene

Post-translational modifications for C15orf61 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C15orf61 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C15orf61 Gene

Domains & Families for C15orf61 Gene

Gene Families for C15orf61 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C15orf61 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C15orf61: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C15orf61 Gene

Function for C15orf61 Gene

Phenotypes for C15orf61 Gene

genes like me logo Genes that share phenotypes with C15orf61: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C15orf61
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C15orf61 Gene

Localization for C15orf61 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C15orf61 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C15orf61 gene
Compartment Confidence
extracellular 4
mitochondrion 1
peroxisome 1
nucleus 1
endoplasmic reticulum 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoli (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for C15orf61 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with C15orf61: view

Pathways & Interactions for C15orf61 Gene

SuperPathways for C15orf61 Gene

No Data Available

Interacting Proteins for C15orf61 Gene

Gene Ontology (GO) - Biological Process for C15orf61 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C15orf61 Gene

Drugs & Compounds for C15orf61 Gene

No Compound Related Data Available

Transcripts for C15orf61 Gene

mRNA/cDNA for C15orf61 Gene

Unigene Clusters for C15orf61 Gene

Chromosome 15 open reading frame 61:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C15orf61
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C15orf61 Gene

No ASD Table

Relevant External Links for C15orf61 Gene

GeneLoc Exon Structure for
C15orf61
ECgene alternative splicing isoforms for
C15orf61

Expression for C15orf61 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C15orf61 Gene

Protein differential expression in normal tissues from HIPED for C15orf61 Gene

This gene is overexpressed in Bone (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C15orf61 Gene



Protein tissue co-expression partners for C15orf61 Gene

NURSA nuclear receptor signaling pathways regulating expression of C15orf61 Gene:

C15orf61

SOURCE GeneReport for Unigene cluster for C15orf61 Gene:

Hs.438385

Evidence on tissue expression from TISSUES for C15orf61 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with C15orf61: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C15orf61 Gene

Orthologs for C15orf61 Gene

This gene was present in the common ancestor of animals.

Orthologs for C15orf61 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C15H15orf61 33
  • 99.57 (n)
C15orf61 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C30H15orf61 33
  • 94.48 (n)
C15orf61 34
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C15orf61 34
  • 94 (a)
OneToOne
C10H15orf61 33
  • 93.84 (n)
mouse
(Mus musculus)
Mammalia 2300009A05Rik 33 16 34
  • 92.57 (n)
rat
(Rattus norvegicus)
Mammalia RGD1309779 33
  • 91.51 (n)
chicken
(Gallus gallus)
Aves C10H15orf61 33
  • 80.48 (n)
C15orf61 34
  • 76 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488454 33
  • 65.37 (n)
zebrafish
(Danio rerio)
Actinopterygii zgc:162898 33
  • 63.42 (n)
C18H15orf61 34
  • 63 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000793 33
  • 63.99 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG34148 33 34
  • 56.33 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 47 (a)
OneToOne
Species where no ortholog for C15orf61 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C15orf61 Gene

ENSEMBL:
Gene Tree for C15orf61 (if available)
TreeFam:
Gene Tree for C15orf61 (if available)

Paralogs for C15orf61 Gene

No data available for Paralogs for C15orf61 Gene

Variants for C15orf61 Gene

Sequence variations from dbSNP and Humsavar for C15orf61 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1000254365 -- 67,524,141(+) CTTAA(A/G)TTTAT intron-variant
rs1000775517 -- 67,519,215(+) TCTGT(A/C)GCTCA intron-variant, upstream-variant-2KB
rs1000788598 -- 67,519,440(+) CCAAA(C/G)TGCTG intron-variant, upstream-variant-2KB
rs1000910884 -- 67,526,426(+) TTCCA(A/C)CTTTA reference, missense
rs1000990649 -- 67,525,660(+) TTGAC(C/T)GAGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C15orf61 Gene

Variant ID Type Subtype PubMed ID
esv3636789 CNV loss 21293372
nsv569799 CNV loss 21841781

Variation tolerance for C15orf61 Gene

Gene Damage Index Score: 1.53; 29.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C15orf61 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C15orf61

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C15orf61 Gene

Disorders for C15orf61 Gene

Relevant External Links for C15orf61

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C15orf61

No disorders were found for C15orf61 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C15orf61 Gene

Publications for C15orf61 Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 4 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo MF … Soares MB (Genome research 1996) 3 60

Products for C15orf61 Gene

Sources for C15orf61 Gene

Content
Loading form....