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Aliases for C15orf61 Gene

Aliases for C15orf61 Gene

  • Chromosome 15 Open Reading Frame 61 2 3 5

External Ids for C15orf61 Gene

Previous GeneCards Identifiers for C15orf61 Gene

  • GC15P065600
  • GC15P067813
  • GC15P044649

Summaries for C15orf61 Gene

GeneCards Summary for C15orf61 Gene

C15orf61 (Chromosome 15 Open Reading Frame 61) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C15orf61 Gene

Genomics for C15orf61 Gene

Regulatory Elements for C15orf61 Gene

Enhancers for C15orf61 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F067548 1.2 Ensembl ENCODE 11.6 +27.5 27534 1.2 HDGF ARNT CREB3L1 ARID4B SIN3A DMAP1 FEZF1 ZNF2 YY1 SLC30A9 IQCH-AS1 C15orf61 SKOR1 LOC101929076 RNU6-1 MAP2K5 GC15P067716
GH15F067967 1.3 FANTOM5 Ensembl ENCODE 1.6 +447.4 447386 1.5 KLF1 PKNOX1 BMI1 ZFHX2 POLR2A PATZ1 ZNF600 EGR2 RFX1 SP3 PIAS1 LOC101929076 RNU6-1 SKOR1 LOC105370872 C15orf61 GC15M067974 GC15M067840
GH15F067520 0.5 ENCODE 0.8 +0.7 689 3.1 HDGF PKNOX1 CREB3L1 MLX WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 IQCH-AS1 MAP2K5 C15orf61
GH15F067506 0.5 Ensembl 0.4 -14.2 -14167 1.4 HDAC1 PKNOX1 TBL1XR1 ZBTB11 CEBPB POLR2H SMARCA4 KLF16 GLIS1 PBX2 IQCH-AS1 MAP2K5 LOC101929076 RNU6-1 SKOR1 LOC105370872 GC15P067906 C15orf61
GH15F067510 0.4 ENCODE 0.4 -10.0 -10021 1.2 ZNF263 CTCF HDAC1 ZNF362 MTA2 BHLHE40 ZNF384 TFDP1 JUND GATA2 IQCH-AS1 MAP2K5 GC15P067906 C15orf61
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C15orf61 on UCSC Golden Path with GeneCards custom track

Promoters for C15orf61 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000410172 732 3201 HDGF PKNOX1 CREB3L1 MLX WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2

Genomic Location for C15orf61 Gene

Chromosome:
15
Start:
67,521,068 bp from pter
End:
67,530,143 bp from pter
Size:
9,076 bases
Orientation:
Plus strand

Genomic View for C15orf61 Gene

Genes around C15orf61 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C15orf61 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C15orf61 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C15orf61 Gene

Proteins for C15orf61 Gene

  • Protein details for C15orf61 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NNL5-CO061_HUMAN
    Recommended name:
    Uncharacterized protein C15orf61
    Protein Accession:
    A6NNL5
    Secondary Accessions:
    • B4DFB2

    Protein attributes for C15orf61 Gene

    Size:
    157 amino acids
    Molecular mass:
    18091 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C15orf61 Gene

Post-translational modifications for C15orf61 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C15orf61 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C15orf61 Gene

Domains & Families for C15orf61 Gene

Protein Domains for C15orf61 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C15orf61: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C15orf61 Gene

Function for C15orf61 Gene

Phenotypes for C15orf61 Gene

genes like me logo Genes that share phenotypes with C15orf61: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C15orf61 Gene

Localization for C15orf61 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C15orf61 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C15orf61 Gene COMPARTMENTS Subcellular localization image for C15orf61 gene
Compartment Confidence
extracellular 4
cytosol 1
endoplasmic reticulum 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C15orf61 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with C15orf61: view

Pathways & Interactions for C15orf61 Gene

SuperPathways for C15orf61 Gene

No Data Available

Interacting Proteins for C15orf61 Gene

Gene Ontology (GO) - Biological Process for C15orf61 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C15orf61 Gene

Transcripts for C15orf61 Gene

mRNA/cDNA for C15orf61 Gene

Unigene Clusters for C15orf61 Gene

Chromosome 15 open reading frame 61:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C15orf61 Gene

No ASD Table

Relevant External Links for C15orf61 Gene

GeneLoc Exon Structure for
C15orf61
ECgene alternative splicing isoforms for
C15orf61

Expression for C15orf61 Gene

mRNA expression in normal human tissues for C15orf61 Gene

Protein differential expression in normal tissues from HIPED for C15orf61 Gene

This gene is overexpressed in Bone (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C15orf61 Gene



Protein tissue co-expression partners for C15orf61 Gene

NURSA nuclear receptor signaling pathways regulating expression of C15orf61 Gene:

C15orf61

SOURCE GeneReport for Unigene cluster for C15orf61 Gene:

Hs.438385
genes like me logo Genes that share expression patterns with C15orf61: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C15orf61 Gene

Orthologs for C15orf61 Gene

This gene was present in the common ancestor of animals.

Orthologs for C15orf61 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C15H15orf61 34
  • 99.57 (n)
C15orf61 35
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C30H15orf61 34
  • 94.48 (n)
C15orf61 35
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C15orf61 35
  • 94 (a)
OneToOne
C10H15orf61 34
  • 93.84 (n)
mouse
(Mus musculus)
Mammalia 2300009A05Rik 34 16 35
  • 92.57 (n)
rat
(Rattus norvegicus)
Mammalia RGD1309779 34
  • 91.51 (n)
chicken
(Gallus gallus)
Aves C10H15orf61 34
  • 80.48 (n)
C15orf61 35
  • 76 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488454 34
  • 65.37 (n)
zebrafish
(Danio rerio)
Actinopterygii zgc:162898 34
  • 63.42 (n)
C18H15orf61 35
  • 63 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000793 34
  • 63.99 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG34148 34 35
  • 56.33 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 47 (a)
OneToOne
Species where no ortholog for C15orf61 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C15orf61 Gene

ENSEMBL:
Gene Tree for C15orf61 (if available)
TreeFam:
Gene Tree for C15orf61 (if available)

Paralogs for C15orf61 Gene

No data available for Paralogs for C15orf61 Gene

Variants for C15orf61 Gene

Sequence variations from dbSNP and Humsavar for C15orf61 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs10518729 -- 67,527,311(+) AACTG(A/T)AATGG downstream-variant-500B
rs112029798 -- 67,526,201(+) ACCCG(C/T)CTTGT intron-variant
rs112086440 -- 67,525,729(+) AGTAA(C/T)GTTGG intron-variant
rs112201720 -- 67,519,323(+) AGGCA(A/T)GTGCC intron-variant, upstream-variant-2KB
rs112387515 -- 67,527,172(+) TTAAT(A/G)TAAGT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C15orf61 Gene

Variant ID Type Subtype PubMed ID
esv3636789 CNV loss 21293372
nsv569799 CNV loss 21841781

Variation tolerance for C15orf61 Gene

Gene Damage Index Score: 1.53; 29.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C15orf61 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C15orf61

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C15orf61 Gene

Disorders for C15orf61 Gene

Relevant External Links for C15orf61

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C15orf61

No disorders were found for C15orf61 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C15orf61 Gene

Publications for C15orf61 Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3 64

Products for C15orf61 Gene

Sources for C15orf61 Gene

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