C15orf61 Gene
protein-coding GIFtS: 32
GCID: GC15P067813
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chromosome 15 open reading frame 61
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Aliases for C15orf61 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Chromosome 15 Open Reading Frame 611 2 | | LOC1458531 | | Uncharacterized Protein C15orf612 |
Export aliases for C15orf61 gene to outside databasesPrevious GC identifers: GC15P065600 GC15P044649 |
Summaries for C15orf61 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Views for C15orf61 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the C15orf61 gene promoter: AP-1 ATF-2 IRF-1 Nkx2-5 c-Jun POU3F2 RSRFC4 Other transcription factors
Search SABiosciences Chromatin IP Primers for C15orf61
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C15orf61 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q23 Ensembl cytogenetic band: 15q23 HGNC cytogenetic band: 15q23C15orf61 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P067813: view genomic region
(about GC identifiers)
Start:
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67,813,406 bp from pter |
End:
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67,819,641 bp from pter |
Size:
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6,236 bases |
Orientation:
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plus strand |
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Proteins for C15orf61 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: CO061_HUMAN, A6NNL5 (See
protein sequence)Recommended Name: Uncharacterized protein C15orf61 precursor Size: 157 amino acids; 18091 Da
Subcellular location: Secreted (Potential)
Secondary accessions: B4DFB2Explore the universe of human proteins at neXtProt for C15orf61: NX_A6NNL5
C15orf61 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001137408.1 ENSEMBL proteins: ENSP00000342254 ENSP00000453824 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- |
C15orf61 for ontologies About GeneDecksing
C15orf61 Antibody Products: Assay Products for C15orf61: |
Protein
Domains / Families for C15orf61 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: A6NNL5 |
Function for C15orf61 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf61 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf61 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C15orf61 (NM_001143936) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C15orf61 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C15orf61  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C15orf61 |
|
Pathways & Interactions for C15orf61 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C15orf61
|
Drugs & Compounds for C15orf61 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for C15orf61 Search CenterWatch for drugs/clinical trials and news about C15orf61 / CO061 
|
Transcripts for C15orf61 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for C15orf61 gene: NM_001143936.1 Unigene Cluster for C15orf61: Chromosome 15 open reading frame 61 Hs.438385 [show with all ESTs]Unigene Representative Sequence: NM_0011439364 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000342683(uc002aqs.3) ENST00000560041 ENST00000557807 ENST00000560547
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf61 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf61 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C15orf61 (NM_001143936) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C15orf61 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C15orf61  |
Additional cDNA sequence: AK294012.1 AY726587.1 7 DOTS entries: DT.101967301 DT.411237 DT.75104944 DT.40302164 DT.91714869 DT.423927 DT.92449192 24/39 AceView cDNA sequences (see all 39): AA932128 AA420989 AI972890 BI962974 BQ025984 CK903599 BM844502 BM701491 BX115629 AJ346153 AI083721 AI204127 AI674485 CF144848 BG771448 BF438062 BU568037 AJ707161 AI475694 AA412015 AA609146 BG189618 AA970879 AI003932 GeneLoc Exon Structure
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Expression for C15orf61 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C15orf61 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TATTGAAAGT
About this image See C15orf61 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for C15orf61
SOURCE GeneReport for Unigene cluster: Hs.438385 SABiosciences Custom PCR Arrays for C15orf61
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C15orf61 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C15orf61 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C15orf61 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C15orf61 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C15orf61 |
Orthologs for C15orf61 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for C15orf61 gene from 3/13 species (see all 13) About this table
ENSEMBL Gene Tree for C15orf61 (if available) TreeFam Gene Tree for C15orf61 (if available)  |
Paralogs for C15orf61 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for C15orf61 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 15 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
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HapMap Linkage Disequilibrium report for C15orf61 (67813406 - 67819641 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for C15orf61: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C15orf61 |
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Disorders
/ Diseases for C15orf61 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications for C15orf61 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C15orf61 gene integrated from 9 sources: (articles sorted by number of sources associating them with C15orf61) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)1, 2 Zody M.C....Nusbaum C. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
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External Searches for C15orf61 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
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Genome Databases showing C15orf61 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C15orf61 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C15orf61 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for C15orf61 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for C15orf61 gene: Search GeneIP for patents involving C15orf61
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for C15orf61 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for C15orf61 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C15orf61 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C15orf61 | | OriGene Protein Over-expression Lysate for C15orf61 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for C15orf61 | | OriGene 3'-UTR Clone for C15orf61 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf61 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf61 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for C15orf61 | | OriGene Custom Protein Services for C15orf61 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C15orf61 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C15orf61 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C15orf61 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C15orf61 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C15orf61 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C15orf61 |
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 | | C15orf61 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C15orf61 |
|  |  |  | | | Search ThermoFisher Antibodies for C15orf61 |
| | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C15orf61 |
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