Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C15orf57 Gene

Aliases for C15orf57 Gene

  • Chromosome 15 Open Reading Frame 57 2 3 5
  • Coiled-Coil Domain Containing 32 2 3
  • CCDC32 3 4
  • Protein CCDC32 4

External Ids for C15orf57 Gene

Previous HGNC Symbols for C15orf57 Gene

  • CCDC32

Previous GeneCards Identifiers for C15orf57 Gene

  • GC15M038633
  • GC15M040845
  • GC15M017688
  • GC15M040820

Summaries for C15orf57 Gene

GeneCards Summary for C15orf57 Gene

C15orf57 (Chromosome 15 Open Reading Frame 57) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C15orf57 Gene

Genomics for C15orf57 Gene

Regulatory Elements for C15orf57 Gene

Enhancers for C15orf57 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C15orf57 on UCSC Golden Path with GeneCards custom track

Promoters for C15orf57 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C15orf57 on UCSC Golden Path with GeneCards custom track

Genomic Location for C15orf57 Gene

40,528,683 bp from pter
40,565,057 bp from pter
36,375 bases
Minus strand

Genomic View for C15orf57 Gene

Genes around C15orf57 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C15orf57 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C15orf57 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C15orf57 Gene

Proteins for C15orf57 Gene

  • Protein details for C15orf57 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C15orf57
    Protein Accession:
    Secondary Accessions:
    • A8KAL4
    • Q86TC4
    • Q8N788
    • Q8NAR7

    Protein attributes for C15orf57 Gene

    185 amino acids
    Molecular mass:
    20656 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAD89911.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for C15orf57 Gene


neXtProt entry for C15orf57 Gene

Proteomics data for C15orf57 Gene at MOPED

Post-translational modifications for C15orf57 Gene

  • Ubiquitination at Lys 119
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for C15orf57 Gene

Domains & Families for C15orf57 Gene

Protein Domains for C15orf57 Gene


Suggested Antigen Peptide Sequences for C15orf57 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C15orf57: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C15orf57 Gene

Function for C15orf57 Gene

Phenotypes for C15orf57 Gene

genes like me logo Genes that share phenotypes with C15orf57: view

Animal Model Products

CRISPR Products

miRNA for C15orf57 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C15orf57 Gene

Localization for C15orf57 Gene

Subcellular locations from

Jensen Localization Image for C15orf57 Gene COMPARTMENTS Subcellular localization image for C15orf57 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C15orf57 Gene

Pathways & Interactions for C15orf57 Gene

SuperPathways for C15orf57 Gene

No Data Available

Interacting Proteins for C15orf57 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: Q9BV29-CO057_HUMAN ENSP00000452773 for C15orf57 Gene via UniProtKB STRING

Gene Ontology (GO) - Biological Process for C15orf57 Gene


No data available for Pathways by source and SIGNOR curated interactions for C15orf57 Gene

Drugs & Compounds for C15orf57 Gene

No Compound Related Data Available

Transcripts for C15orf57 Gene

Unigene Clusters for C15orf57 Gene

Chromosome 15 open reading frame 57:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C15orf57 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c ^ 8
SP1: - - - - -
SP2: - - - -
SP3: - - - - - - - - -
SP4: - - - - -
SP5: - - - - - - - -
SP6: - - - - - - - - - - - -
SP7: - - - - - - - -
SP8: - - -
SP9: - - -
SP10: - -
SP11: - -
SP12: - - - - - - - -

Relevant External Links for C15orf57 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C15orf57 Gene

mRNA expression in normal human tissues for C15orf57 Gene

Protein differential expression in normal tissues from HIPED for C15orf57 Gene

This gene is overexpressed in Testis (28.2) and Fetal testis (10.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C15orf57 Gene

SOURCE GeneReport for Unigene cluster for C15orf57 Gene Hs.654661

genes like me logo Genes that share expression patterns with C15orf57: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C15orf57 Gene

Orthologs for C15orf57 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C15orf57 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C10H15orf57 35
  • 90.32 (n)
  • 87.15 (a)
CCDC32 36
  • 89 (a)
(Canis familiaris)
Mammalia C30H15orf57 35
  • 91.62 (n)
  • 91.62 (a)
C15orf57 36
  • 90 (a)
(Mus musculus)
Mammalia Ccdc32 35
  • 88.08 (n)
  • 86.03 (a)
Ccdc32 16
Ccdc32 36
  • 85 (a)
(Pan troglodytes)
Mammalia C15H15orf57 35
  • 99.83 (n)
  • 100 (a)
C15orf57 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Ccdc32 35
  • 87.34 (n)
  • 84.92 (a)
(Monodelphis domestica)
Mammalia C15orf57 36
  • 71 (a)
(Gallus gallus)
Aves C5H15ORF57 35
  • 73.75 (n)
  • 71.26 (a)
C5H15ORF57 36
  • 70 (a)
(Anolis carolinensis)
Reptilia C15orf57 36
  • 65 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c15orf57 35
  • 59.55 (n)
  • 53.37 (a)
(Danio rerio)
Actinopterygii LOC564862 35
  • 59.02 (n)
  • 50 (a)
C17H15orf57 36
  • 45 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2757 35
Species with no ortholog for C15orf57:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C15orf57 Gene

Gene Tree for C15orf57 (if available)
Gene Tree for C15orf57 (if available)

Paralogs for C15orf57 Gene

No data available for Paralogs for C15orf57 Gene

Variants for C15orf57 Gene

Sequence variations from dbSNP and Humsavar for C15orf57 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs10152546 - 40,563,011(+) ACATT(A/T)TCATT reference, missense
rs6582 -- 40,553,398(+) AGAGA(A/G)AGAAG intron-variant, utr-variant-3-prime
rs5015628 -- 40,565,964(+) GGGGG(C/G)GTTGA upstream-variant-2KB
rs5812165 -- 40,544,733(+) TTGGA(-/T)TTTTT intron-variant
rs6492952 -- 40,542,900(+) tgcct(A/G)taatc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C15orf57 Gene

Variant ID Type Subtype PubMed ID
esv34145 CNV Loss 18971310
nsv832984 CNV Loss 17160897
dgv739e1 CNV Complex 17122850
esv2749601 CNV Deletion 23290073
esv2749602 CNV Deletion 23290073
nsv507777 CNV Insertion 20534489

Variation tolerance for C15orf57 Gene

Residual Variation Intolerance Score: 54.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.57; 86.10% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C15orf57 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C15orf57 Gene

Disorders for C15orf57 Gene

Relevant External Links for C15orf57

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C15orf57 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C15orf57 Gene

Publications for C15orf57 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  4. The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. (PMID: 25277244) Katsogiannou M. … Rocchi P. (Mol. Cell Proteomics 2014) 3
  5. Identification of cellular factors binding to acetylated HIV-1 integrase. (PMID: 20016921) Allouch A. … Cereseto A. (Amino Acids 2011) 3

Products for C15orf57 Gene

Sources for C15orf57 Gene