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Aliases for C15orf54 Gene

Aliases for C15orf54 Gene

  • Chromosome 15 Open Reading Frame 54 2 3

External Ids for C15orf54 Gene

Previous GeneCards Identifiers for C15orf54 Gene

  • GC15P037331
  • GC15P039542
  • GC15P016386

Summaries for C15orf54 Gene

GeneCards Summary for C15orf54 Gene

C15orf54 (Chromosome 15 Open Reading Frame 54) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C15orf54 Gene

Genomics for C15orf54 Gene

Regulatory Elements for C15orf54 Gene

Genomic Location for C15orf54 Gene

Chromosome:
15
Start:
39,250,669 bp from pter
End:
39,254,845 bp from pter
Size:
4,177 bases
Orientation:
Plus strand

Genomic View for C15orf54 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for C15orf54 Gene

Proteins for C15orf54 Gene

  • Protein details for C15orf54 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8G6-CO054_HUMAN
    Recommended name:
    Putative uncharacterized protein C15orf54
    Protein Accession:
    Q8N8G6
    Secondary Accessions:
    • B7ZVZ9

    Protein attributes for C15orf54 Gene

    Size:
    183 amino acids
    Molecular mass:
    21040 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C15orf54 Gene

Proteomics data for C15orf54 Gene at MOPED

Post-translational modifications for C15orf54 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C15orf54 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C15orf54 Gene

Domains & Families for C15orf54 Gene

Protein Domains for C15orf54 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C15orf54: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C15orf54 Gene

Function for C15orf54 Gene

Phenotypes for C15orf54 Gene

genes like me logo Genes that share phenotypes with C15orf54: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C15orf54

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C15orf54 Gene

Localization for C15orf54 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C15orf54 Gene

Pathways & Interactions for C15orf54 Gene

SuperPathways for C15orf54 Gene

No Data Available

Interacting Proteins for C15orf54 Gene

Gene Ontology (GO) - Biological Process for C15orf54 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C15orf54 Gene

Drugs & Compounds for C15orf54 Gene

No Compound Related Data Available

Transcripts for C15orf54 Gene

mRNA/cDNA for C15orf54 Gene

(2) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C15orf54 Gene

Chromosome 15 open reading frame 54:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C15orf54

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C15orf54 Gene

No ASD Table

Relevant External Links for C15orf54 Gene

GeneLoc Exon Structure for
C15orf54
ECgene alternative splicing isoforms for
C15orf54

Expression for C15orf54 Gene

mRNA expression in normal human tissues for C15orf54 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C15orf54 Gene

This gene is overexpressed in Whole Blood (x5.3) and Minor Salivary Gland (x5.2).

SOURCE GeneReport for Unigene cluster for C15orf54 Gene Hs.376109

genes like me logo Genes that share expression patterns with C15orf54: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C15orf54 Gene

Orthologs for C15orf54 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C15orf54 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia C30H15orf54 35
  • 85.42 (n)
  • 75 (a)
chimpanzee
(Pan troglodytes)
Mammalia C15H15orf54 35
  • 97.81 (n)
  • 95.08 (a)
Species with no ortholog for C15orf54:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C15orf54 Gene

ENSEMBL:
Gene Tree for C15orf54 (if available)
TreeFam:
Gene Tree for C15orf54 (if available)

Paralogs for C15orf54 Gene

No data available for Paralogs for C15orf54 Gene

Variants for C15orf54 Gene

Sequence variations from dbSNP and Humsavar for C15orf54 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs156657 -- 39,249,331(+) attag(C/T)gctag upstream-variant-2KB
rs156783 -- 39,252,831(+) GTATT(G/T)CACTA utr-variant-3-prime
rs156784 -- 39,253,067(-) CTTTA(C/T)ATTTA utr-variant-3-prime
rs156785 -- 39,255,171(+) TTCTT(A/G)AATAG downstream-variant-500B
rs156789 -- 39,250,174(+) gtctg(C/T)ttctg upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C15orf54 Gene

Variant ID Type Subtype PubMed ID
dgv2358n71 CNV Loss 21882294

Variation tolerance for C15orf54 Gene

Residual Variation Intolerance Score: 68.54% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.37; 27.10% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C15orf54 Gene

HapMap Linkage Disequilibrium report
C15orf54

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C15orf54 Gene

Disorders for C15orf54 Gene

Relevant External Links for C15orf54

Genetic Association Database (GAD)
C15orf54
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C15orf54
genes like me logo Genes that share disorders with C15orf54: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C15orf54 Gene

Publications for C15orf54 Gene

  1. Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. (PMID: 23934736) Yu B. … Boerwinkle E. (Genet. Epidemiol. 2013) 67
  2. Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality. (PMID: 21348951) Parsa A. … Liggett S.B. (Clin Transl Sci 2011) 67
  3. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PMID: 17903300) Fox C.S. … Atwood L.D. (BMC Med. Genet. 2007) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for C15orf54 Gene

Sources for C15orf54 Gene

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