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Aliases for C15orf53 Gene

Aliases for C15orf53 Gene

  • Chromosome 15 Open Reading Frame 53 2 3

External Ids for C15orf53 Gene

Previous GeneCards Identifiers for C15orf53 Gene

  • GC15P036777
  • GC15P038988
  • GC15P015833

Summaries for C15orf53 Gene

GeneCards Summary for C15orf53 Gene

C15orf53 (Chromosome 15 Open Reading Frame 53) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C15orf53 Gene

Genomics for C15orf53 Gene

Regulatory Elements for C15orf53 Gene

Genomic Location for C15orf53 Gene

38,696,598 bp from pter
38,700,038 bp from pter
3,441 bases
Plus strand

Genomic View for C15orf53 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C15orf53 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C15orf53 Gene

Proteins for C15orf53 Gene

  • Protein details for C15orf53 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C15orf53
    Protein Accession:
    Secondary Accessions:

    Protein attributes for C15orf53 Gene

    179 amino acids
    Molecular mass:
    19737 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C15orf53 Gene

Proteomics data for C15orf53 Gene at MOPED

Post-translational modifications for C15orf53 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C15orf53 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for C15orf53 Gene

Domains for C15orf53 Gene

Protein Domains for C15orf53 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C15orf53: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C15orf53 Gene

Function for C15orf53 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C15orf53

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C15orf53 Gene

Localization for C15orf53 Gene

Subcellular locations from

Jensen Localization Image for C15orf53 Gene COMPARTMENTS Subcellular localization image for C15orf53 gene
Compartment Confidence
cytosol 2
extracellular 2
nucleus 2
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C15orf53 Gene

Pathways for C15orf53 Gene

SuperPathways for C15orf53 Gene

No Data Available

Interacting Proteins for C15orf53 Gene

Gene Ontology (GO) - Biological Process for C15orf53 Gene


No data available for Pathways by source for C15orf53 Gene

Transcripts for C15orf53 Gene

mRNA/cDNA for C15orf53 Gene

(3) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C15orf53 Gene

Chromosome 15 open reading frame 53:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C15orf53

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C15orf53 Gene

No ASD Table

Relevant External Links for C15orf53 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C15orf53 Gene

mRNA expression in normal human tissues for C15orf53 Gene

mRNA differential expression in normal tissues according to GTEx for C15orf53 Gene

This gene is overexpressed in Whole Blood (9.8).

SOURCE GeneReport for Unigene cluster for C15orf53 Gene Hs.448785

genes like me logo Genes that share expressions with C15orf53: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for C15orf53 Gene

Orthologs for C15orf53 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C15orf53 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C15H15orf53 35
  • 97.95 (n)
  • 98.31 (a)
C15orf53 36
  • 98 (a)
Species with no ortholog for C15orf53:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C15orf53 Gene

Gene Tree for C15orf53 (if available)
Gene Tree for C15orf53 (if available)

Paralogs for C15orf53 Gene

No data available for Paralogs for C15orf53 Gene

Variants for C15orf53 Gene

Sequence variations from dbSNP and Humsavar for C15orf53 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs1472293 -- 38,697,718(+) AGTAG(C/G)AACCG intron-variant
rs1472294 -- 38,697,868(+) GGGCA(A/C/T)CCTTA intron-variant
rs1472295 -- 38,696,283(-) AAAAC(C/T)GTGGC upstream-variant-2KB
rs1472296 -- 38,696,078(-) CCAGA(C/T)GCAGT upstream-variant-2KB
rs1495185 -- 38,699,235(+) CCCAT(C/G)AAGTA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C15orf53 Gene

Variant ID Type Subtype PubMed ID
nsv525770 CNV Gain 19592680

Relevant External Links for C15orf53 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C15orf53 Gene

Disorders for C15orf53 Gene

Relevant External Links for C15orf53

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for C15orf53 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C15orf53 Gene

Publications for C15orf53 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. (PMID: 18711365) Ferreira M.A. … Craddock N. (Nat. Genet. 2008) 3 48
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Genome-wide association study of bipolar disorder in European American and African American individuals. (PMID: 19488044) Smith E.N. … Kelsoe J.R. (Mol. Psychiatry 2009) 3
  5. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (PMID: 21926972) (Nat. Genet. 2011) 3

Products for C15orf53 Gene

Sources for C15orf53 Gene

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