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Aliases for C15orf52 Gene

Aliases for C15orf52 Gene

  • Chromosome 15 Open Reading Frame 52 2 3 5

External Ids for C15orf52 Gene

Previous GeneCards Identifiers for C15orf52 Gene

  • GC15M038411
  • GC15M040624
  • GC15M017467

Summaries for C15orf52 Gene

GeneCards Summary for C15orf52 Gene

C15orf52 (Chromosome 15 Open Reading Frame 52) is a Protein Coding gene. GO annotations related to this gene include poly(A) RNA binding. An important paralog of this gene is CCDC9.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C15orf52 Gene

Genomics for C15orf52 Gene

Regulatory Elements for C15orf52 Gene

Enhancers for C15orf52 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around C15orf52 on UCSC Golden Path with GeneCards custom track

Promoters for C15orf52 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for C15orf52 Gene

40,331,452 bp from pter
40,340,967 bp from pter
9,516 bases
Minus strand

Genomic View for C15orf52 Gene

Genes around C15orf52 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C15orf52 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C15orf52 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C15orf52 Gene

Proteins for C15orf52 Gene

  • Protein details for C15orf52 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C15orf52
    Protein Accession:
    Secondary Accessions:
    • B9EIQ8
    • Q68DG9
    • Q6ZTM3
    • Q6ZU22

    Protein attributes for C15orf52 Gene

    534 amino acids
    Molecular mass:
    57325 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAH18251.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for C15orf52 Gene


neXtProt entry for C15orf52 Gene

Post-translational modifications for C15orf52 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C15orf52 Gene

No data available for DME Specific Peptides for C15orf52 Gene

Domains & Families for C15orf52 Gene

Protein Domains for C15orf52 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C15orf52: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C15orf52 Gene

Function for C15orf52 Gene

Gene Ontology (GO) - Molecular Function for C15orf52 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with C15orf52: view
genes like me logo Genes that share phenotypes with C15orf52: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C15orf52 Gene

Localization for C15orf52 Gene

Subcellular locations from

Jensen Localization Image for C15orf52 Gene COMPARTMENTS Subcellular localization image for C15orf52 gene
Compartment Confidence
cytosol 3
nucleus 3
extracellular 2
lysosome 1
vacuole 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C15orf52 Gene

Pathways & Interactions for C15orf52 Gene

SuperPathways for C15orf52 Gene

No Data Available

Interacting Proteins for C15orf52 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000453969 Q6ZUT6-CO052_HUMAN for C15orf52 Gene via STRING IID

Gene Ontology (GO) - Biological Process for C15orf52 Gene


No data available for Pathways by source and SIGNOR curated interactions for C15orf52 Gene

Drugs & Compounds for C15orf52 Gene

No Compound Related Data Available

Transcripts for C15orf52 Gene

Unigene Clusters for C15orf52 Gene

Chromosome 15 open reading frame 52:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C15orf52 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8
SP1: - -
SP2: - -
SP3: - -

Relevant External Links for C15orf52 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C15orf52 Gene

mRNA expression in normal human tissues for C15orf52 Gene

mRNA differential expression in normal tissues according to GTEx for C15orf52 Gene

This gene is overexpressed in Colon - Sigmoid (x4.1).

Protein differential expression in normal tissues from HIPED for C15orf52 Gene

This gene is overexpressed in Colon (15.6), Peripheral blood mononuclear cells (12.7), Testis (12.1), and Rectum (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C15orf52 Gene

Protein tissue co-expression partners for C15orf52 Gene

NURSA nuclear receptor signaling pathways regulating expression of C15orf52 Gene:


SOURCE GeneReport for Unigene cluster for C15orf52 Gene:

genes like me logo Genes that share expression patterns with C15orf52: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for C15orf52 Gene

Orthologs for C15orf52 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C15orf52 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C10H15orf52 34
  • 81.18 (n)
  • 73.73 (a)
C15orf52 35
  • 68 (a)
(Canis familiaris)
Mammalia C30H15orf52 34
  • 81.45 (n)
  • 75.38 (a)
C15orf52 35
  • 71 (a)
(Pan troglodytes)
Mammalia C15H15orf52 34
  • 97.88 (n)
  • 96.63 (a)
C15orf52 35
  • 97 (a)
(Monodelphis domestica)
Mammalia C15orf52 35
  • 37 (a)
(Mus musculus)
Mammalia A430105I19Rik 35
  • 59 (a)
A430105I19Rik 16
A430105I19Rik 34
  • 74.72 (n)
  • 65.47 (a)
(Ornithorhynchus anatinus)
Mammalia C15orf52 35
  • 47 (a)
(Gallus gallus)
Aves C5H15ORF52 34
  • 58.25 (n)
  • 49.83 (a)
(Anolis carolinensis)
Reptilia C15orf52 35
  • 29 (a)
(Danio rerio)
Actinopterygii C17H15orf52 35
  • 22 (a)
Species where no ortholog for C15orf52 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C15orf52 Gene

Gene Tree for C15orf52 (if available)
Gene Tree for C15orf52 (if available)

Paralogs for C15orf52 Gene

Paralogs for C15orf52 Gene

genes like me logo Genes that share paralogs with C15orf52: view

Variants for C15orf52 Gene

Sequence variations from dbSNP and Humsavar for C15orf52 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
VAR_035620 A colorectal cancer sample
rs3067241 -- 40,333,588(+) aaaaa(-/AAAA/AAAAA)GACGA utr-variant-3-prime
rs4923864 -- 40,342,516(+) cattc(A/G)tataa upstream-variant-2KB
rs4924454 -- 40,332,573(+) GAACC(A/C/G)GAGCT utr-variant-3-prime
rs4924455 -- 40,340,937(+) TGCTC(A/T)GCACA reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for C15orf52 Gene

Variant ID Type Subtype PubMed ID
esv34145 CNV loss 18971310
nsv1160287 CNV duplication 26073780
nsv510660 CNV deletion 20534489
nsv827305 CNV gain 20364138

Variation tolerance for C15orf52 Gene

Residual Variation Intolerance Score: 94.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.68; 65.95% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C15orf52 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C15orf52 Gene

Disorders for C15orf52 Gene

Relevant External Links for C15orf52

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C15orf52 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C15orf52 Gene

Publications for C15orf52 Gene

  1. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 65
  2. The central role of EED in the orchestration of polycomb group complexes. (PMID: 24457600) Cao Q. … Chinnaiyan A.M. (Nat Commun 2014) 3 65
  3. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 4 65
  4. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 65
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 65

Products for C15orf52 Gene

Sources for C15orf52 Gene

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