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Aliases for C15orf52 Gene

Aliases for C15orf52 Gene

  • Chromosome 15 Open Reading Frame 52 2 3

External Ids for C15orf52 Gene

Previous GeneCards Identifiers for C15orf52 Gene

  • GC15M038411
  • GC15M040624
  • GC15M017467

Summaries for C15orf52 Gene

GeneCards Summary for C15orf52 Gene

C15orf52 (Chromosome 15 Open Reading Frame 52) is a Protein Coding gene. Diseases associated with C15orf52 include colorectal cancer. An important paralog of this gene is CCDC9.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C15orf52 Gene

Genomics for C15orf52 Gene

Regulatory Elements for C15orf52 Gene

Genomic Location for C15orf52 Gene

40,331,452 bp from pter
40,340,967 bp from pter
9,516 bases
Minus strand

Genomic View for C15orf52 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C15orf52 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C15orf52 Gene

Proteins for C15orf52 Gene

  • Protein details for C15orf52 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C15orf52
    Protein Accession:
    Secondary Accessions:
    • B9EIQ8
    • Q68DG9
    • Q6ZTM3
    • Q6ZU22

    Protein attributes for C15orf52 Gene

    534 amino acids
    Molecular mass:
    57325 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAH18251.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for C15orf52 Gene


neXtProt entry for C15orf52 Gene

Proteomics data for C15orf52 Gene at MOPED

Post-translational modifications for C15orf52 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C15orf52 Gene

No data available for DME Specific Peptides for C15orf52 Gene

Domains for C15orf52 Gene

Protein Domains for C15orf52 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C15orf52: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C15orf52 Gene

Function for C15orf52 Gene

Gene Ontology (GO) - Molecular Function for C15orf52 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with C15orf52: view

Animal Model Products

CRISPR Products

miRNA for C15orf52 Gene

miRTarBase miRNAs that target C15orf52

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for C15orf52 Gene

Localization for C15orf52 Gene

Subcellular locations from

Jensen Localization Image for C15orf52 Gene COMPARTMENTS Subcellular localization image for C15orf52 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 1
lysosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C15orf52 Gene

Pathways for C15orf52 Gene

SuperPathways for C15orf52 Gene

No Data Available

Interacting Proteins for C15orf52 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000453969 for C15orf52 Gene via STRING

Gene Ontology (GO) - Biological Process for C15orf52 Gene


No data available for Pathways by source for C15orf52 Gene

Transcripts for C15orf52 Gene

Unigene Clusters for C15orf52 Gene

Chromosome 15 open reading frame 52:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C15orf52

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C15orf52 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8
SP1: - -
SP2: - -
SP3: - -

Relevant External Links for C15orf52 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C15orf52 Gene

mRNA expression in normal human tissues for C15orf52 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C15orf52 Gene

This gene is overexpressed in Colon - Sigmoid (4.1).

Protein differential expression in normal tissues for C15orf52 Gene

This gene is overexpressed in Colon (15.6), Peripheral blood mononuclear cells (12.7), Testis (12.1), and Rectum (6.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C15orf52 Gene

SOURCE GeneReport for Unigene cluster for C15orf52 Gene Hs.32433

genes like me logo Genes that share expressions with C15orf52: view

Expression partners for C15orf52 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for C15orf52 Gene

Orthologs for C15orf52 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C15orf52 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C10H15orf52 35
  • 81.18 (n)
  • 73.73 (a)
C15orf52 36
  • 68 (a)
(Canis familiaris)
Mammalia C30H15orf52 35
  • 81.45 (n)
  • 75.38 (a)
C15orf52 36
  • 71 (a)
(Mus musculus)
Mammalia A430105I19Rik 35
  • 74.72 (n)
  • 65.47 (a)
A430105I19Rik 16
A430105I19Rik 36
  • 59 (a)
(Pan troglodytes)
Mammalia C15H15orf52 35
  • 97.88 (n)
  • 96.63 (a)
C15orf52 36
  • 97 (a)
(Monodelphis domestica)
Mammalia C15orf52 36
  • 37 (a)
(Ornithorhynchus anatinus)
Mammalia C15orf52 36
  • 47 (a)
(Gallus gallus)
Aves C5H15ORF52 35
  • 58.25 (n)
  • 49.83 (a)
(Anolis carolinensis)
Reptilia C15orf52 36
  • 29 (a)
(Danio rerio)
Actinopterygii C17H15orf52 36
  • 22 (a)
Species with no ortholog for C15orf52:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C15orf52 Gene

Gene Tree for C15orf52 (if available)
Gene Tree for C15orf52 (if available)

Paralogs for C15orf52 Gene

Paralogs for C15orf52 Gene

genes like me logo Genes that share paralogs with C15orf52: view

Variants for C15orf52 Gene

Sequence variations from dbSNP and Humsavar for C15orf52 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs748245 -- 40,337,116(-) CCTAA(A/T)GGGTG intron-variant
rs1129264 -- 40,331,623(-) GAACG(C/T)GCCTA utr-variant-3-prime
rs377016111 -- 40,337,469(+) GTCAG(A/G)TTGCT intron-variant
rs377023271 -- 40,339,639(+) GGGGT(C/T)AGCAC intron-variant
rs377093193 -- 40,340,831(+) GGCGG(A/G)CACCG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C15orf52 Gene

Variant ID Type Subtype PubMed ID
esv34145 CNV Loss 18971310
nsv510660 CNV Loss 20534489
nsv827305 CNV Gain 20364138

Relevant External Links for C15orf52 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C15orf52 Gene

Disorders for C15orf52 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for C15orf52 Gene in MalaCards »

(1) Disease for C15orf52 Gene

genes like me logo Genes that share disorders with C15orf52: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for C15orf52 Gene

Publications for C15orf52 Gene

  1. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  5. The central role of EED in the orchestration of polycomb group complexes. (PMID: 24457600) Cao Q. … Chinnaiyan A.M. (Nat Commun 2014) 3

Products for C15orf52 Gene

Sources for C15orf52 Gene

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