Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

C15orf48 Gene

protein-coding GIFtS: 45
GCID: GC15P045722

chromosome 15 open reading frame 48

Explore 6 diseases affiliated with
C15orf48 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Chromosome 15 Open Reading Frame 48¹ ²
NMES1¹ ² ⁵
FOAP-11²
Normal Mucosa Of Esophagus Specific 1²
Normal Mucosa Of Esophagus-Specific Gene 1 Protein²
Protein FOAP-11³

External Ids:	HGNC: 29898¹	Entrez Gene: 84419²	Ensembl: ENSG00000166920⁷	OMIM: 608409⁵	UniProtKB: Q9C002³

Export aliases for C15orf48 gene to outside databases

Previous GC identifers: GC15P043511 GC15P022547

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for C15orf48:

This gene was first identified in a study of human esophageal squamous cell carcinoma tissues. Levels of both the

message and protein are reduced in carcinoma samples. In adult human tissues, this gene is expressed in the the

esophagus, stomach, small intestine, colon and placenta. Alternatively spliced transcript variants that encode the

same protein have been identified. (provided by RefSeq, Jun 2012)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000015.9 NC_018926.1 NT_010194.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the C15orf48 gene promoter:
STAT1 Bach2 FOXD1 E47 NF-AT N-Myc NF-AT4 NF-AT2 NF-AT3 NF-AT1
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for C15orf48

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C15orf48

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q21.1 Ensembl cytogenetic band: 15q21.1 HGNC cytogenetic band: 15q21.1

C15orf48 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C15orf48 gene location

GeneLoc information about chromosome 15 GeneLoc Exon Structure

GeneLoc location for GC15P045722: view genomic region (about GC identifiers)

Start:	45,722,727 bp from pter	End:	45,740,959 bp from pter
Size:	18,233 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NMES1_HUMAN, Q9C002 (See protein sequence)

Recommended Name: Normal mucosa of esophagus-specific gene 1 protein

Size: 83 amino acids; 9617 Da

Subcellular location: Nucleus

Explore the universe of human proteins at neXtProt for C15orf48: NX_Q9C002

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9C002

C15orf48 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_115789.1 NP_922946.1

ENSEMBL proteins:

ENSP00000379887 ENSP00000452967 ENSP00000341610

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate (see all 3): C15orf48 OriGene Custom Protein Services for C15orf48
	GenScript Custom Purified and Recombinant Proteins Services for C15orf48
	Novus Biologicals C15orf48 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for C15orf48

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	12209954
GO:0005739	mitochondrion	IEA	--

C15orf48 for ontologies About GeneDecksing

C15orf48 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for C15orf48
	GenScript Custom Superior Antibodies Services for C15orf48
	Novus Biologicals C15orf48 Antibody
	Search for Antibodies for C15orf48 at Abcam
	Uscn Antibodies for C15orf48
	Search ThermoFisher Antibodies for C15orf48

Assay Products for C15orf48:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for C15orf48
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for C15orf48

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

C15orf48 for domains About GeneDecksing

1 InterPro domain/family:

IPR010530 B12D

Graphical View of Domain Structure for InterPro Entry Q9C002

ProtoNet protein and cluster: Q9C002

UniProtKB/Swiss-Prot: NMES1_HUMAN, Q9C002

Similarity: Belongs to the complex I NDUFA4 subunit family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C15orf48
		8 QIAGEN miScript miRNA Assays for microRNAs that regulate C15orf48:
		hsa-miR-28-3p hsa-miR-298 hsa-miR-513a-3p hsa-miR-143* hsa-miR-4282 hsa-miR-548c-3p hsa-miR-2113 hsa-miR-3692

		SwitchGear 3'UTR luciferase reporter plasmid: C15orf48 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C15orf48 (see all 4) OriGene shRNA RFP: C15orf48 OriGene siRNA: C15orf48
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C15orf48

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for C15orf48

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf48 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf48 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): C15orf48 (NM_032413)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for C15orf48
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C15orf48

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for C15orf48
		Search LifeMap BioReagents cell lines for C15orf48

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C15orf48

1 GenomeRNAi human phenotype for C15orf48:

Increased number of cells in m

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for C15orf48

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for C15orf48 (ENSP00000341610⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ABL2	ENSP00000356595⁴	STRING: ENSP00000356595
TSSK3	ENSP00000362634⁴	STRING: ENSP00000362634

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for C15orf48
Search CenterWatch for drugs/clinical trials and news about C15orf48 / NMES1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for C15orf48 gene (2 alternative transcripts):

NM_032413.3 NM_197955.2

Unigene Cluster for C15orf48:

Chromosome 15 open reading frame 48

Hs.112242 [show with all ESTs]

Unigene Representative Sequence: NM_032413

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000396650 ENST00000558435 ENST00000344300(uc001zvg.3 uc001zvh.3)

ENST00000558632

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C15orf48
		8 QIAGEN miScript miRNA Assays for microRNAs that regulate C15orf48:
		hsa-miR-28-3p hsa-miR-298 hsa-miR-513a-3p hsa-miR-143* hsa-miR-4282 hsa-miR-548c-3p hsa-miR-2113 hsa-miR-3692

		SwitchGear 3'UTR luciferase reporter plasmid: C15orf48 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C15orf48 (see all 4) OriGene shRNA RFP: C15orf48 OriGene siRNA: C15orf48
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C15orf48

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf48 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf48 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): C15orf48 (NM_032413)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for C15orf48
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C15orf48

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C15orf48 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat C15orf48
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C15orf48
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C15orf48

Additional cDNA sequence:

AB026707.1 AF228422.1 AK026298.1 BC021173.2

7 DOTS entries:

DT.100755295 DT.91758671 DT.99958682 DT.100025292 DT.100755294 DT.40131427 DT.95112615

24/94 AceView cDNA sequences (see all 94):

BM504909 BM504582 BU949284 AW665458 AI207367 NM_197955 BQ631958 AK026298

BQ217789 AI625959 BM312626 BM838465 D20798 AA298786 BQ632294 CA309087

AI335741 AA298773 AW176424 BQ218935 BQ632588 AA758348 AA620995 AB026707

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

C15orf48 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTGTGGCGG

About this image

C15orf48 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 4 LifeMap Cells

Name

Category

PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)

Heart, Myocardium, Smooth Muscle

PureStem™ progenitor E44 (Embryonic Progenitor Cell)

PureStem™ progenitor EN2 (Embryonic Progenitor Cell)

PureStem™ progenitor SK17 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See C15orf48 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C15orf48

SOURCE GeneReport for Unigene cluster: Hs.112242

UniProtKB/Swiss-Prot: NMES1_HUMAN, Q9C002

Tissue specificity: Expressed mainly in stomach, placenta, small intestine and colon, as well as in normal mucosa of

esophagus. Down-regulated in esophageal squamous cell carcinoma

SABiosciences Custom PCR Arrays for C15orf48

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C15orf48 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat C15orf48
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C15orf48
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C15orf48

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C15orf48

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for C15orf48 gene from 4/11 species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	AA467197^{1 , 5}	expressed sequence AA467197^{1, 5}	76.71(n)¹ 72.29(a)¹		2 (60.64 cM)⁵ 433470¹ NM_001004174.1¹ NP_001004174.1¹ 122636986⁵
chicken (Gallus gallus)	Aves	C15orf48⁶	--	60(a)	1 ↔ 1	10(11999-13592)
lizard (Anolis carolinensis)	Reptilia	C15orf48⁶	--	64(a)	1 ↔ 1	GL343506.1(18129-19012)
zebrafish (Danio rerio)	Actinopterygii	zgc:153317¹	zgc:153317	61.18(n) 60.76(a)		751757 NM_001198748.1 NP_001185677.1

ENSEMBL Gene Tree for C15orf48 (if available)
TreeFam Gene Tree for C15orf48 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 15 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs2433612^1,2	C,F,H,	--	45721040(+)	`GAGTCG/TCTTTA`	2	--	us2k¹		9		NS EA NA WA CSA	544
rs77231101^1,2	C,	--	45721073(+)	`TGAGCC/TGAGAT`	2	--	us2k¹		0	--	--	--	--
rs1153846^1,2		--	45721111(+)	`cagagC/Agagac`	2	--	us2k¹		2		NA	4
rs143311930^1,2		--	45721204(+)	`AGAATA/GCTTTA`	2	--	us2k¹		0	--	--	--	--
rs138810690^1,2		--	45721269(+)	`TGCAGA/GTATAT`	2	--	us2k¹		0	--	--	--	--
rs182642736^1,2		--	45721308(+)	`TTACTC/TAAAGT`	2	--	us2k¹		0	--	--	--	--
rs186913767^1,2		--	45721336(+)	`TATAGC/TAGGGG`	2	--	us2k¹		0	--	--	--	--
rs1288847^1,2	C,F,H,	--	45721575(+)	`ACCTGC/TGTTCT`	2	--	us2k¹		13		NS EA NA WA CSA	1488
rs114234852^1,2	F,	--	45721626(+)	`TCTCTG/CAGTCT`	2	--	us2k¹		1		WA	118
rs142817962^1,2		--	45721756(+)	`TGCTGC/GCTTAG`	2	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for C15orf48 (45722727 - 45740959 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C15orf48: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C15orf48

DNA2.0 Custom Variant and Variant Library Synthesis for C15orf48

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

C15orf48 for disorders           About GeneDecksing

OMIM gene information: 608409    OMIM disorders: --

6 diseases for C15orf48:    About MalaCards

esophageal squamous cell carcinoma squamous cell carcinoma esophagitis carcinoma

cervical carcinoma cervicitis

Human Genome Epidemiology (HuGE) Navigator: C15orf48 (1 document)

Export disorders for C15orf48 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for C15orf48 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C15orf48)

Utopia: connect your pdf to the dynamic
world of online information

A novel gene, NMES1, downregulated in human esophageal squamous cell carcinoma. (PubMed id 12209954)^{1, 2, 3} Zhou J.... Liu Z. (2002)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
A regulatory dendritic cell signature correlates with the clinical efficacy of allergen-specific sublingual immunotherapy. (PubMed id 22464673)¹ Zimmer A....Moingeon P. (2012)
Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)¹ Hendrickson S.L....O'Brien S.J. (2010)
Analysis of the methylation status of genes up-regulated by the demethylating agent, 5-aza-2'-deoxycytidine, in esophageal squamous cell carcinoma. (PubMed id 18636205)¹ Arai M....Yokosuka O. (2008)
Discovery of novel methylation biomarkers in cervical carcinoma by global demethylation and microarray analysis. (PubMed id 16434596)¹ Sova P....Kiviat N. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 84419	HGNC: 29898	AceView: NMES1	Ensembl:ENSG00000166920	euGenes: HUgn84419
ECgene: C15orf48	H-InvDB: C15orf48

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for C15orf48	Pharmacogenomics, SNPs, Pathways

Intellectual Property for C15orf48 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for C15orf48 gene:
Search GeneIP for patents involving C15orf48

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for C15orf48
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C15orf48		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C15orf48
	OriGene Protein Over-expression Lysate for C15orf48		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for C15orf48		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf48		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf48
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for C15orf48		OriGene Custom Protein Services for C15orf48
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C15orf48
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C15orf48
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C15orf48
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C15orf48
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C15orf48
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C15orf48

	GenScript Custom Purified and Recombinant Proteins Services for C15orf48		GenScript cDNA clones with any tag delivered in your preferred vector for C15orf48
	GenScript Custom Assay Services for C15orf48		GenScript Custom Superior Antibodies Services for C15orf48
	GenScript Custom overexpressing Cell Line Services for C15orf48		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in C15orf48 promoter
	Search Chromatin IP Primers for C15orf48
	RT² qPCR Primer Assay in human, mouse, rat C15orf48
	Search GNC Networks for C15orf48
	SABiosciences Custom PCR Arrays for C15orf48

Search Tocris compounds for C15orf48

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	C15orf48 antibodies
	C15orf48 lysates

	Search for Antibodies for C15orf48 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for C15orf48
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

C15orf48 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for C15orf48

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C15orf48

	SwitchGear 3'UTR luciferase reporter plasmids for C15orf48
	Browse SwitchGear Promoter luciferase reporter plasmids for C15orf48

Search ThermoFisher Antibodies for C15orf48

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C15orf48

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes C15orf48 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

C15orf48 Gene

chromosome 15 open reading frame 48

Aliases
for C15orf48 gene

Summaries
for C15orf48 gene

Genomic Views
for C15orf48 gene

Proteins
for C15orf48 gene

Protein Domains /
Families
for C15orf48 gene

Function
for C15orf48 gene

Pathways & Interactions
for C15orf48 gene

Drugs & Compounds
for C15orf48 gene

Transcripts
for C15orf48 gene

Expression
for C15orf48 gene

Orthologs
for C15orf48 gene

Paralogs
for C15orf48 gene

Genomic Variants
for C15orf48 gene

Disorders / Diseases
for C15orf48 gene

Publications
for C15orf48 gene

External Searches for C15orf48 gene

Genome Databases showing C15orf48 gene

Other Databases showing C15orf48 gene

Specialized Databases showing C15orf48 gene

Intellectual Property
for C15orf48 gene

Products
for C15orf48 gene

View Random Gene

Advanced Search

Export list of displayed genes

C15orf48 Gene

chromosome 15 open reading frame 48

Aliasesfor C15orf48 gene

Summariesfor C15orf48 gene

Genomic Viewsfor C15orf48 gene

Proteinsfor C15orf48 gene

Protein Domains /Familiesfor C15orf48 gene

Functionfor C15orf48 gene

Pathways & Interactionsfor C15orf48 gene

Drugs & Compoundsfor C15orf48 gene

Transcriptsfor C15orf48 gene

Expression for C15orf48 gene

Orthologsfor C15orf48 gene

Paralogsfor C15orf48 gene

Genomic Variantsfor C15orf48 gene

Disorders / Diseasesfor C15orf48 gene

Publicationsfor C15orf48 gene

External Searches for C15orf48 gene

Genome Databases showing C15orf48 gene

Other Databases showing C15orf48 gene

Specialized Databases showing C15orf48 gene

Intellectual Propertyfor C15orf48 gene

Productsfor C15orf48 gene

View Random Gene

Aliases
for C15orf48 gene

Summaries
for C15orf48 gene

Genomic Views
for C15orf48 gene

Proteins
for C15orf48 gene

Protein Domains /
Families
for C15orf48 gene

Function
for C15orf48 gene

Pathways & Interactions
for C15orf48 gene

Drugs & Compounds
for C15orf48 gene

Transcripts
for C15orf48 gene

Expression
for C15orf48 gene

Orthologs
for C15orf48 gene

Paralogs
for C15orf48 gene

Genomic Variants
for C15orf48 gene

Disorders / Diseases
for C15orf48 gene

Publications
for C15orf48 gene

Intellectual Property
for C15orf48 gene

Products
for C15orf48 gene