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Aliases for C15orf39 Gene

Aliases for C15orf39 Gene

  • Chromosome 15 Open Reading Frame 39 2 3 5

External Ids for C15orf39 Gene

Previous GeneCards Identifiers for C15orf39 Gene

  • GC15P073279
  • GC15P075491
  • GC15P052290

Summaries for C15orf39 Gene

GeneCards Summary for C15orf39 Gene

C15orf39 (Chromosome 15 Open Reading Frame 39) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C15orf39 Gene

Genomics for C15orf39 Gene

Regulatory Elements for C15orf39 Gene

Enhancers for C15orf39 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C15orf39 on UCSC Golden Path with GeneCards custom track

Genomic Location for C15orf39 Gene

Chromosome:
15
Start:
75,195,643 bp from pter
End:
75,212,169 bp from pter
Size:
16,527 bases
Orientation:
Plus strand

Genomic View for C15orf39 Gene

Genes around C15orf39 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C15orf39 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C15orf39 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C15orf39 Gene

Proteins for C15orf39 Gene

  • Protein details for C15orf39 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZRI6-CO039_HUMAN
    Recommended name:
    Uncharacterized protein C15orf39
    Protein Accession:
    Q6ZRI6
    Secondary Accessions:
    • B3KWI3
    • C9J888
    • Q71JB1
    • Q7L3S0
    • Q8N3F2
    • Q96FB6
    • Q9NTU5

    Protein attributes for C15orf39 Gene

    Size:
    1047 amino acids
    Molecular mass:
    110673 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAQ06680.1; Type=Frameshift; Positions=267; Evidence={ECO:0000305}; Sequence=CAB55985.3; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAD39045.1; Type=Frameshift; Positions=900; Evidence={ECO:0000305};

    Alternative splice isoforms for C15orf39 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C15orf39 Gene

Proteomics data for C15orf39 Gene at MOPED

Post-translational modifications for C15orf39 Gene

  • Ubiquitination at Lys 620 and Lys 898
  • Modification sites at PhosphoSitePlus

Other Protein References for C15orf39 Gene

No data available for DME Specific Peptides for C15orf39 Gene

Domains & Families for C15orf39 Gene

Protein Domains for C15orf39 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for C15orf39 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C15orf39: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C15orf39 Gene

Function for C15orf39 Gene

genes like me logo Genes that share phenotypes with C15orf39: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C15orf39 Gene

Localization for C15orf39 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C15orf39 Gene COMPARTMENTS Subcellular localization image for C15orf39 gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C15orf39 Gene

Pathways & Interactions for C15orf39 Gene

SuperPathways for C15orf39 Gene

No Data Available

Interacting Proteins for C15orf39 Gene

Gene Ontology (GO) - Biological Process for C15orf39 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C15orf39 Gene

Drugs & Compounds for C15orf39 Gene

No Compound Related Data Available

Transcripts for C15orf39 Gene

Unigene Clusters for C15orf39 Gene

Chromosome 15 open reading frame 39:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C15orf39 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b
SP1: -
SP2:
SP3:
SP4: -
SP5: - -
SP6:

Relevant External Links for C15orf39 Gene

GeneLoc Exon Structure for
C15orf39
ECgene alternative splicing isoforms for
C15orf39

Expression for C15orf39 Gene

mRNA expression in normal human tissues for C15orf39 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C15orf39 Gene

This gene is overexpressed in Whole Blood (x9.9) and Testis (x4.1).

Protein differential expression in normal tissues from HIPED for C15orf39 Gene

This gene is overexpressed in Saliva (28.9), Pancreatic juice (21.4), Heart (11.7), and Placenta (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C15orf39 Gene



SOURCE GeneReport for Unigene cluster for C15orf39 Gene Hs.17936

genes like me logo Genes that share expression patterns with C15orf39: view

Protein tissue co-expression partners for C15orf39 Gene

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for C15orf39 Gene

Orthologs for C15orf39 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C15orf39 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C21H15orf39 35
  • 81.82 (n)
  • 77.42 (a)
C15orf39 36
  • 76 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C30H15orf39 35
  • 79.99 (n)
  • 75.82 (a)
C15orf39 36
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700017B05Rik 35
  • 78.48 (n)
  • 76.31 (a)
1700017B05Rik 16
1700017B05Rik 36
  • 77 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C15H15orf39 35
  • 99.01 (n)
  • 98.38 (a)
C15orf39 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1305464 35
  • 79.55 (n)
  • 77.08 (a)
oppossum
(Monodelphis domestica)
Mammalia C15orf39 36
  • 45 (a)
OneToOne
chicken
(Gallus gallus)
Aves C15orf39 36
  • 42 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C15orf39 36
  • 45 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii Dr.14401 35
C18H15orf39 36
  • 22 (a)
OneToOne
Species with no ortholog for C15orf39:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C15orf39 Gene

ENSEMBL:
Gene Tree for C15orf39 (if available)
TreeFam:
Gene Tree for C15orf39 (if available)

Paralogs for C15orf39 Gene

Pseudogenes.org Pseudogenes for C15orf39 Gene

genes like me logo Genes that share paralogs with C15orf39: view

No data available for Paralogs for C15orf39 Gene

Variants for C15orf39 Gene

Sequence variations from dbSNP and Humsavar for C15orf39 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1873379 - 75,206,403(-) GTGAG(C/G)CTGGG reference, missense, utr-variant-5-prime
rs11072532 - 75,207,520(+) GGAGG(A/G/T)CGCAA reference, missense
rs28509789 - 75,207,654(+) CTGAC(G/T)CAGCC reference, missense
rs3743211 - 75,210,806(-) GCTCA(C/T)CTCTG reference, missense, utr-variant-3-prime
rs7161754 -- 75,209,444(+) CCTCC(C/G)CGGCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C15orf39 Gene

Variant ID Type Subtype PubMed ID
nsv904383 CNV Gain 21882294
nsv833056 CNV Gain 17160897
nsv904384 CNV Loss 21882294
nsv904385 CNV Loss 21882294

Variation tolerance for C15orf39 Gene

Residual Variation Intolerance Score: 92.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.94; 83.92% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C15orf39 Gene

Disorders for C15orf39 Gene

Relevant External Links for C15orf39

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C15orf39

No disorders were found for C15orf39 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C15orf39 Gene

Publications for C15orf39 Gene

  1. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PMID: 15498874) Wan D. … Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  4. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. (PMID: 26673895) KA+rlA+ K. … GAPrlich D. (Elife 2015) 3
  5. Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover. (PMID: 24999758) Elzi D.J. … Shiio Y. (J. Proteome Res. 2014) 3

Products for C15orf39 Gene

Sources for C15orf39 Gene

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