C15orf38-AP3S2 Gene
protein-coding GIFtS: 21
GCID: GC15M090378
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C15orf38-AP3S2 readthrough
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Aliases
for C15orf38-AP3S2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
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| Aliases |
|---|
| C15orf38-AP3S2 Readthrough1 2 | | C15orf38-AP3S2 Fusion Protein2 |
Export aliases for C15orf38-AP3S2 gene to outside databasesPrevious GC identifer: GC15U901312 |
Summaries
for C15orf38-AP3S2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for C15orf38-AP3S2:
This locus represents naturally occurring read-through transcription between the neighboring C15orf38 (chromosome 15open reading frame 38) and AP3S2 (adaptor-related protein complex 3, sigma 2 subunit) genes. The read-throughtranscript encodes a fusion protein that shares sequence identity with each individual gene product. (provided byRefSeq, Nov 2010)
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Genomic Views
for C15orf38-AP3S2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for C15orf38-AP3S2
Other transcription factors
Search SABiosciences Chromatin IP Primers for C15orf38-AP3S2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C15orf38-AP3S2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q Ensembl cytogenetic band: 15q26.1 HGNC cytogenetic band: 15q26.1C15orf38-AP3S2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M090378: view genomic region
(about GC identifiers)
Start:
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90,377,540 bp from pter |
End:
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90,456,114 bp from pter |
Size:
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78,575 bases |
Orientation:
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minus strand |
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Proteins
for C15orf38-AP3S2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/TrEMBL: E2QRD5 (See
protein sequence)Recommended Name: Protein C15orf38-AP3S2 Size: 394 amino acids; 43882 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataUniProtKB/TrEMBL: H0YL85 (See
protein sequence) Recommended Name: Protein C15orf38-AP3S2 Size: 185 amino acids; 20448 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataUniProtKB/TrEMBL: H0YMK0 (See
protein sequence) Recommended Name: Protein C15orf38-AP3S2 Size: 184 amino acids; 20721 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataUniProtKB/TrEMBL: H0YN38 (See
protein sequence) Recommended Name: Protein C15orf38-AP3S2 Size: 156 amino acids; 18180 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataC15orf38-AP3S2 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_001185987.1
ENSEMBL proteins: ENSP00000381377 ENSP00000453852 ENSP00000453100 ENSP00000453637
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0030117 | membrane coat |
-- | -- |
C15orf38-AP3S2 for ontologies About GeneDecksing
C15orf38-AP3S2 Antibody Products:
Assay Products for C15orf38-AP3S2: |
Protein
Domains /
Families
for C15orf38-AP3S2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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C15orf38-AP3S2 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry E2QRD5Graphical View of Domain Structure for InterPro Entry H0YL85Graphical View of Domain Structure for InterPro Entry H0YMK0Graphical View of Domain Structure for InterPro Entry H0YN38ProtoNet protein and cluster: E2QRD5 |
Function
for C15orf38-AP3S2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C15orf38-AP3S2 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0008565 | protein transporter activity |
-- | -- |
C15orf38-AP3S2 for ontologies About GeneDecksing
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Pathways & Interactions
for C15orf38-AP3S2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C15orf38-AP3S2
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0006810 | transport |
-- | -- | | GO:0006886 | intracellular protein transport |
-- | -- | | GO:0016192 | vesicle-mediated transport |
-- | -- |
C15orf38-AP3S2 for ontologies About GeneDecksing
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Drugs & Compounds
for C15orf38-AP3S2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
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 Browse Tocris compounds for C15orf38-AP3S2
Search CenterWatch for drugs/clinical trials and news about C15orf38-AP3S2 
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Transcripts
for C15orf38-AP3S2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for C15orf38-AP3S2 gene: NM_001199058.1 7 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000398333 ENST00000560940 ENST00000560771 ENST00000561410 ENST00000558648
ENST00000559629 ENST00000560224
GeneLoc Exon Structure
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Expression
for C15orf38-AP3S2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C15orf38-AP3S2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image SABiosciences Custom PCR Arrays for C15orf38-AP3S2
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat C15orf38-AP3S2 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C15orf38-AP3S2 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C15orf38-AP3S2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C15orf38-AP3S2 |
Orthologs
for C15orf38-AP3S2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for C15orf38-AP3S2 gene from 1/10 species (see all 10) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc:1124321 |
zgc:112432 |
58.7(n)
57.96(a) |
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550477 NM_001017780.1 NP_001017780.1 |
ENSEMBL Gene Tree for C15orf38-AP3S2 (if available)
TreeFam Gene Tree for C15orf38-AP3S2 (if available) |
Paralogs
for C15orf38-AP3S2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C15orf38-AP3S2 gene
- C15orf381 2
9 SIMAP similar genes for C15orf38-AP3S2 using alignment to 4 protein entries: E2QRD5_HUMAN (see all proteins):C15orf38 AP3S2 AP3S1 AP4S1 AP2S1 DKFZp779P0659
AP1S1 AP1S2 AP1S3
C15orf38-AP3S2 for paralogs About GeneDecksing
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Genomic Variants
for C15orf38-AP3S2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C15orf38-AP3S2 (90377540 - 90456114 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C15orf38-AP3S2: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for C15orf38-AP3S2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C15orf38-AP3S2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for C15orf38-AP3S2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C15orf38-AP3S2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. (PubMed id 21874001)1 Kooner J.S....Chambers J.C. (2011)
- Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PubMed id 20967262)1 Prakash T....Taylor T.D. (2010)
- Web-based, participant-driven studies yield novel gen etic associations for common traits. (PubMed id 20585627)1 Eriksson N....Mountain J. (2010)
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External Searches for C15orf38-AP3S2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing C15orf38-AP3S2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing C15orf38-AP3S2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C15orf38-AP3S2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for C15orf38-AP3S2 gene:
Search GeneIP for patents involving C15orf38-AP3S2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for C15orf38-AP3S2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C15orf38-AP3S2 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C15orf38-AP3S2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C15orf38-AP3S2 | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C15orf38-AP3S2 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C15orf38-AP3S2 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C15orf38-AP3S2 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C15orf38-AP3S2 |
|  |  |  | | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C15orf38-AP3S2 |
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