C15orf38 Gene
protein-coding GIFtS: 37
GCID: GC15M090443
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chromosome 15 open reading frame 38
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Aliases
for C15orf38 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 15 Open Reading Frame 381 2 | | MGC615501 | | UPF0552 Protein C15orf382 |
Export aliases for C15orf38 gene to outside databasesPrevious GC identifers: GC15M088244 GC15M088178 GC15M090414 GC15M066555 |
Summaries
for C15orf38 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C15orf38 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010274.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C15orf38 gene promoter:
STAT1 AP-1 GCNF POU3F1 MyoD HEN1 PPAR-gamma1 FOXO4 ARP-1 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for C15orf38
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C15orf38 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q26.1 Ensembl cytogenetic band: 15q26.1 HGNC cytogenetic band: 15q26.1C15orf38 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M090443: view genomic region
(about GC identifiers)
Start:
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90,443,159 bp from pter |
End:
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90,456,222 bp from pter |
Size:
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13,064 bases |
Orientation:
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minus strand |
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Proteins
for C15orf38 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CO038_HUMAN, Q7Z6K5 (See
protein sequence)Recommended Name: UPF0552 protein C15orf38 Size: 226 amino acids; 24943 DaExplore the universe of human proteins at neXtProt for C15orf38: NX_Q7Z6K5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7Z6K5
C15orf38 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_872422.1
ENSEMBL proteins: ENSP00000350075 ENSP00000453687 ENSP00000453006
Human Recombinant Protein Products:
C15orf38 Antibody Products:
Assay Products for C15orf38: |
Protein
Domains /
Families
for C15orf38 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
C15orf38 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q7Z6K5ProtoNet protein and cluster: Q7Z6K5 UniProtKB/Swiss-Prot: CO038_HUMAN, Q7Z6K5Similarity: Belongs to the UPF0552 family |
Function
for C15orf38 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf38
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf38
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C15orf38 (NM_182616) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C15orf38 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C15orf38 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C15orf38 |
1 GenomeRNAi human phenotype for C15orf38:
|
Pathways & Interactions
for C15orf38 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C15orf38
|
Drugs & Compounds
for C15orf38 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C15orf38
Search CenterWatch for drugs/clinical trials and news about C15orf38 / CO038
|
Transcripts
for C15orf38 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C15orf38 gene: NM_182616.2 Unigene Cluster for C15orf38: Chromosome 15 open reading frame 38 Hs.6734 [show with all ESTs]Unigene Representative Sequence: NM_0011990583 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000357484(uc002bou.2) ENST00000460685(uc002bot.1) ENST00000560096
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf38
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf38
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C15orf38 (NM_182616) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C15orf38 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C15orf38 |
Additional cDNA sequence: AK093274.1 AL832121.1 BC053602.1 BX640690.1 9 DOTS entries: DT.441702 DT.97774837 DT.95164295 DT.100652671 DT.121061821 DT.97768955 DT.87015743 DT.121061794 DT.100685529 24/436 AceView cDNA sequences (see all 436): BQ061146 BU957474 AA419029 BQ058203 BX421715 AI677927 AI620187 BM712778 AW069139 BM853935 AU279481 BQ068166 AW271425 CD743011 AX748027 AK000495 BU151451 F25137 BC002785 M85771 AA313909 AA662829 AA626083 BM544767
GeneLoc Exon Structure
|
Expression
for C15orf38 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C15orf38 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See C15orf38 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C15orf38
SOURCE GeneReport for Unigene cluster: Hs.6734
SABiosciences Custom PCR Arrays for C15orf38
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C15orf38
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C15orf38 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C15orf38 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C15orf38 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C15orf38 |
Orthologs
for C15orf38 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C15orf38 gene from 1/11 species (see all 11) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.158652 |
Transcribed sequences |
76.89(n) |
|
AL914786.1 |
ENSEMBL Gene Tree for C15orf38 (if available)
TreeFam Gene Tree for C15orf38 (if available) |
Paralogs
for C15orf38 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C15orf38 gene
- C15orf38-AP3S21 2
1 SIMAP similar gene for C15orf38 using alignment to 3 protein entries: CO038_HUMAN (see all proteins):C15orf38-AP3S2
C15orf38 for paralogs About GeneDecksing
|
Genomic Variants
for C15orf38 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C15orf38 (90443159 - 90456222 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C15orf38: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C15orf38 |
|
Disorders
/ Diseases
for C15orf38 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C15orf38 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C15orf38 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C15orf38) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Web-based, participant-driven studies yield novel gen etic associations for common traits. (PubMed id 20585627)1 Eriksson N....Mountain J. (2010)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
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External Searches for C15orf38 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C15orf38 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C15orf38 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C15orf38 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C15orf38 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C15orf38 gene:
Search GeneIP for patents involving C15orf38
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C15orf38 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C15orf38 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C15orf38 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C15orf38 | | | OriGene Protein Over-expression Lysate for C15orf38 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C15orf38 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf38 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C15orf38 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C15orf38 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C15orf38 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C15orf38 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C15orf38 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C15orf38 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C15orf38 |
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 | | | C15orf38 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C15orf38 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C15orf38 |
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