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Aliases for C14orf93 Gene

Aliases for C14orf93 Gene

  • Chromosome 14 Open Reading Frame 93 2 3 5
  • EC 2.4.2.18 63
  • EC 2.4.2.21 63

External Ids for C14orf93 Gene

Previous GeneCards Identifiers for C14orf93 Gene

  • GC14M017243
  • GC14M021446
  • GC14M022525
  • GC14M023456
  • GC14M003573

Summaries for C14orf93 Gene

GeneCards Summary for C14orf93 Gene

C14orf93 (Chromosome 14 Open Reading Frame 93) is a Protein Coding gene. GO annotations related to this gene include poly(A) RNA binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf93 Gene

Genomics for C14orf93 Gene

Regulatory Elements for C14orf93 Gene

Enhancers for C14orf93 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C14orf93 on UCSC Golden Path with GeneCards custom track

Promoters for C14orf93 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C14orf93 on UCSC Golden Path with GeneCards custom track

Genomic Location for C14orf93 Gene

Chromosome:
14
Start:
22,985,908 bp from pter
End:
23,010,201 bp from pter
Size:
24,294 bases
Orientation:
Minus strand

Genomic View for C14orf93 Gene

Genes around C14orf93 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C14orf93 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C14orf93 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf93 Gene

Proteins for C14orf93 Gene

  • Protein details for C14orf93 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H972-CN093_HUMAN
    Recommended name:
    Uncharacterized protein C14orf93
    Protein Accession:
    Q9H972
    Secondary Accessions:
    • B7WP03
    • D3DS38
    • D3DS39
    • Q86SE6
    • Q96CF7
    • Q9HA68

    Protein attributes for C14orf93 Gene

    Size:
    538 amino acids
    Molecular mass:
    58697 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C14orf93 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C14orf93 Gene

Proteomics data for C14orf93 Gene at MOPED

Selected DME Specific Peptides for C14orf93 Gene

Post-translational modifications for C14orf93 Gene

  • Ubiquitination at Lys 71
  • Modification sites at PhosphoSitePlus

Domains & Families for C14orf93 Gene

Protein Domains for C14orf93 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf93: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C14orf93 Gene

Function for C14orf93 Gene

Enzyme Numbers (IUBMB) for C14orf93 Gene

genes like me logo Genes that share phenotypes with C14orf93: view

Animal Model Products

CRISPR Products

miRNA for C14orf93 Gene

miRTarBase miRNAs that target C14orf93

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C14orf93 Gene

Localization for C14orf93 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C14orf93 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C14orf93 Gene COMPARTMENTS Subcellular localization image for C14orf93 gene
Compartment Confidence
extracellular 4
nucleus 3
cytosol 2
plasma membrane 2

No data available for Gene Ontology (GO) - Cellular Components for C14orf93 Gene

Pathways & Interactions for C14orf93 Gene

SuperPathways for C14orf93 Gene

No Data Available

Interacting Proteins for C14orf93 Gene

Gene Ontology (GO) - Biological Process for C14orf93 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C14orf93 Gene

Drugs & Compounds for C14orf93 Gene

No Compound Related Data Available

Transcripts for C14orf93 Gene

Unigene Clusters for C14orf93 Gene

Chromosome 14 open reading frame 93:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf93 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e · 7f · 7g · 7h · 7i ^ 8a · 8b · 8c · 8d ^ 9a · 9b · 9c ^
SP1:
SP2: - - - - - - -
SP3: - - - - - - - - -
SP4: - - - - - - - - - - - - -
SP5: - - - - - -
SP6: - - - - - - - - - - - - -
SP7: - - - -
SP8: - - - - -
SP9: - - - - - - - - - - -
SP10: - - - - - -
SP11: - - - -
SP12: - - - - - - - -
SP13: - - - - - - - -
SP14: - - - - - - - -
SP15: - - - - - - - - -
SP16: - - - - - - - -

ExUns: 10 ^ 11 ^ 12 ^ 13 ^ 14
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:

Relevant External Links for C14orf93 Gene

GeneLoc Exon Structure for
C14orf93
ECgene alternative splicing isoforms for
C14orf93

Expression for C14orf93 Gene

mRNA expression in normal human tissues for C14orf93 Gene

Protein differential expression in normal tissues from HIPED for C14orf93 Gene

This gene is overexpressed in Tlymphocyte (68.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C14orf93 Gene



SOURCE GeneReport for Unigene cluster for C14orf93 Gene Hs.255874

genes like me logo Genes that share expression patterns with C14orf93: view

Protein tissue co-expression partners for C14orf93 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C14orf93 Gene

Orthologs for C14orf93 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C14orf93 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C10H14orf93 35
  • 88.97 (n)
  • 91.45 (a)
C10H14ORF93 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C8H14orf93 35
  • 90.89 (n)
  • 92.57 (a)
C14orf93 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4931414P19Rik 35
  • 84.95 (n)
  • 87.69 (a)
4931414P19Rik 16
4931414P19Rik 36
  • 87 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1565222 35
  • 85.14 (n)
  • 88.06 (a)
oppossum
(Monodelphis domestica)
Mammalia C14orf93 36
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C14orf93 36
  • 82 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C14orf93 36
  • 98 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C14orf93 36
  • 65 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c14orf93 35
  • 59.29 (n)
  • 60.08 (a)
Str.14071 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.3310 35
Species with no ortholog for C14orf93:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C14orf93 Gene

ENSEMBL:
Gene Tree for C14orf93 (if available)
TreeFam:
Gene Tree for C14orf93 (if available)

Paralogs for C14orf93 Gene

No data available for Paralogs for C14orf93 Gene

Variants for C14orf93 Gene

Sequence variations from dbSNP and Humsavar for C14orf93 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs3829409 - 22,998,455(+) CGCTG(A/G)CAGCC reference, missense
rs1318009 -- 22,993,802(+) TTTTG(C/G)TTCAC intron-variant
rs8003201 -- 23,008,384(+) AATTT(A/G)TACAA intron-variant, upstream-variant-2KB
rs8005047 -- 22,995,008(+) ccagg(G/T)tgaga intron-variant
rs8021296 -- 23,004,039(+) agagt(C/T)gctgg intron-variant

Variation tolerance for C14orf93 Gene

Residual Variation Intolerance Score: 76.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.55; 64.89% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for C14orf93 Gene

Disorders for C14orf93 Gene

Relevant External Links for C14orf93

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C14orf93

No disorders were found for C14orf93 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C14orf93 Gene

Publications for C14orf93 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances. (PMID: 23704328) Fatemifar G. … Evans D.M. (Hum. Mol. Genet. 2013) 3
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3

Products for C14orf93 Gene

Sources for C14orf93 Gene

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