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Aliases for C14orf79 Gene

Aliases for C14orf79 Gene

  • Chromosome 14 Open Reading Frame 79 2 3 5

External Ids for C14orf79 Gene

Previous GeneCards Identifiers for C14orf79 Gene

  • GC14M099443
  • GC14P103424
  • GC14P104523
  • GC14P105452
  • GC14P085646

Summaries for C14orf79 Gene

GeneCards Summary for C14orf79 Gene

C14orf79 (Chromosome 14 Open Reading Frame 79) is a Protein Coding gene.

Gene Wiki entry for C14orf79 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf79 Gene

Genomics for C14orf79 Gene

Regulatory Elements for C14orf79 Gene

Enhancers for C14orf79 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G105013 1.7 Ensembl ENCODE dbSUPER 36.4 +35.6 35584 14.8 CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 C14orf79 GPR132 AHNAK2 RPS20P33 CDCA4 GC14P105029
GH14G104966 1.9 FANTOM5 Ensembl ENCODE dbSUPER 24.9 -13.5 -13506 11.9 HDGF PKNOX1 ZFP64 ARID4B SIN3A ZNF2 ZBTB7B ZNF207 ZNF143 FOS C14orf79 AHNAK2 LINC00638 ENSG00000257270 GPR132 IGHE CEP170B INF2 JAG2 CDCA4
GH14G104980 1.3 ENCODE dbSUPER 28.1 -4.6 -4613 4.0 ZNF133 SIN3A FEZF1 GLI4 ZNF2 ZBTB7B YY1 GLIS2 GATA2 ZNF143 ENSG00000257270 C14orf79 TMEM121 RPS20P33 PACS2 AHNAK2 IGHGP CRIP2
GH14G104984 1.2 ENCODE dbSUPER 26.5 -0.2 -197 2.7 HDGF ATF1 ARID4B SIN3A ELK1 ZNF263 SP3 MXD4 REST ZNF579 C14orf79 AHNAK2 GPR132 CRIP2
GH14G105074 1.7 FANTOM5 Ensembl ENCODE dbSUPER 16.5 +89.8 89804 3.0 TBP HDGF KLF17 GLIS2 SCRT2 EGR2 ZBTB11 GATAD2B GLIS1 IKZF1 GPR132 C14orf79 JAG2 NUDT14 LINC02298 PLD4 CRIP1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C14orf79 on UCSC Golden Path with GeneCards custom track

Promoters for C14orf79 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000073746 25 1201 HDGF ATF1 ARID4B SIN3A ELK1 ZNF263 SP3 MXD4 REST ZNF579

Genomic Location for C14orf79 Gene

Chromosome:
14
Start:
104,985,775 bp from pter
End:
105,010,482 bp from pter
Size:
24,708 bases
Orientation:
Plus strand

Genomic View for C14orf79 Gene

Genes around C14orf79 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C14orf79 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C14orf79 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf79 Gene

Proteins for C14orf79 Gene

  • Protein details for C14orf79 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96F83-CN079_HUMAN
    Recommended name:
    Uncharacterized protein C14orf79
    Protein Accession:
    Q96F83
    Secondary Accessions:
    • B2RPK9
    • Q9BTP4

    Protein attributes for C14orf79 Gene

    Size:
    325 amino acids
    Molecular mass:
    35690 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C14orf79 Gene

Post-translational modifications for C14orf79 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C14orf79 Gene

No data available for DME Specific Peptides for C14orf79 Gene

Domains & Families for C14orf79 Gene

Protein Domains for C14orf79 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf79: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C14orf79 Gene

Function for C14orf79 Gene

genes like me logo Genes that share phenotypes with C14orf79: view

Animal Model Products

CRISPR Products

miRNA for C14orf79 Gene

miRTarBase miRNAs that target C14orf79

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C14orf79 Gene

Localization for C14orf79 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C14orf79 gene
Compartment Confidence
nucleus 3
cytosol 3
plasma membrane 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C14orf79 Gene

Pathways & Interactions for C14orf79 Gene

SuperPathways for C14orf79 Gene

No Data Available

Interacting Proteins for C14orf79 Gene

Gene Ontology (GO) - Biological Process for C14orf79 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C14orf79 Gene

Drugs & Compounds for C14orf79 Gene

No Compound Related Data Available

Transcripts for C14orf79 Gene

Unigene Clusters for C14orf79 Gene

Chromosome 14 open reading frame 79:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf79 Gene

No ASD Table

Relevant External Links for C14orf79 Gene

GeneLoc Exon Structure for
C14orf79
ECgene alternative splicing isoforms for
C14orf79

Expression for C14orf79 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C14orf79 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C14orf79 Gene



NURSA nuclear receptor signaling pathways regulating expression of C14orf79 Gene:

C14orf79

SOURCE GeneReport for Unigene cluster for C14orf79 Gene:

Hs.27183
genes like me logo Genes that share expression patterns with C14orf79: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C14orf79 Gene

Orthologs for C14orf79 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C14orf79 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C14ORF79 35
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C21H14orf79 34
  • 72.96 (n)
C14orf79 35
  • 51 (a)
OneToOne
mouse
(Mus musculus)
Mammalia BC022687 34 16 35
  • 72.2 (n)
rat
(Rattus norvegicus)
Mammalia RGD1307315 34
  • 71.16 (n)
dog
(Canis familiaris)
Mammalia C14orf79 35
  • 52 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C14orf79 35
  • 41 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C14orf79 35
  • 34 (a)
OneToOne
chicken
(Gallus gallus)
Aves C5H14ORF79 34
  • 53.74 (n)
C14orf79 35
  • 28 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C14orf79 35
  • 37 (a)
OneToOne
Species where no ortholog for C14orf79 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C14orf79 Gene

ENSEMBL:
Gene Tree for C14orf79 (if available)
TreeFam:
Gene Tree for C14orf79 (if available)

Paralogs for C14orf79 Gene

No data available for Paralogs for C14orf79 Gene

Variants for C14orf79 Gene

Sequence variations from dbSNP and Humsavar for C14orf79 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000277734 -- 104,998,196(+) GAGGC(C/T)GGGAG intron-variant
rs1000469163 -- 104,984,134(+) GGGTG(A/G)GGAAT upstream-variant-2KB
rs1000834875 -- 104,993,943(+) AGCAC(-/AGG)AGGCA intron-variant, cds-indel
rs1000970133 -- 104,994,173(+) ATGTT(C/T)GTGGC intron-variant, utr-variant-3-prime
rs1001040374 -- 104,988,846(+) AATTA(A/C)AAATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C14orf79 Gene

Variant ID Type Subtype PubMed ID
esv3635634 CNV gain 21293372
nsv1042303 CNV gain 25217958
nsv1049253 CNV gain 25217958
nsv1052190 CNV gain 25217958
nsv1054574 CNV loss 25217958
nsv1438 CNV deletion 18451855
nsv456458 CNV loss 19166990
nsv566141 CNV gain 21841781
nsv566150 CNV loss 21841781
nsv566151 CNV loss 21841781
nsv566152 CNV loss 21841781
nsv952276 CNV deletion 24416366

Variation tolerance for C14orf79 Gene

Residual Variation Intolerance Score: 76.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.55; 30.00% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C14orf79 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C14orf79

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C14orf79 Gene

Disorders for C14orf79 Gene

Relevant External Links for C14orf79

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C14orf79

No disorders were found for C14orf79 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C14orf79 Gene

Publications for C14orf79 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  2. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 3 4 64
  3. Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia. (PMID: 16112646) Guinn B.-A. … Mufti G.J. (Biochem. Biophys. Res. Commun. 2005) 3 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C14orf79 Gene

Sources for C14orf79 Gene

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