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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C14orf79 Gene

protein-coding   GIFtS: 39
GCID: GC14P105452

chromosome 14 open reading frame 79
  Search for C14orf79
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for C14orf79    

Aliases
for C14orf79 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Chromosome 14 Open Reading Frame 791 2
Uncharacterized Protein C14orf792

External Ids:    HGNC: 201261   Entrez Gene: 1226162   Ensembl: ENSG000001401047   UniProtKB: Q96F833   

Export aliases for C14orf79 gene to outside databases

Previous GC identifers: GC14M099443 GC14P103424 GC14P104523 GC14P085646


Summaries
for C14orf79 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Gene Wiki entry for C14orf79


Genomic Views
for C14orf79 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the C14orf79 gene promoter:
         GR   AP-2gamma   AREB6   CREB   Egr-2   PPAR-gamma1   Zic1   deltaCREB   GR-alpha   PPAR-gamma2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for C14orf79

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C14orf79


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.33   Ensembl cytogenetic band:  14q32.33   HGNC cytogenetic band: 14q32.33

C14orf79 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C14orf79 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P105452:  view genomic region     (about GC identifiers)

Start:
 105,452,112 bp from pter      End:
 105,476,819 bp from pter
Size:
 24,708 bases      Orientation:
 plus strand

Proteins
for C14orf79 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CN079_HUMAN, Q96F83 (See protein sequence)
Recommended Name: Uncharacterized protein C14orf79  
Size: 325 amino acids; 35690 Da
Secondary accessions: B2RPK9 Q9BTP4

Explore the universe of human proteins at neXtProt for C14orf79: NX_Q96F83

C14orf79 Protein expression data from MOPED and PaxDb:    About this image 
C14orf79 Protein Expression

REFSEQ proteins: NP_777551.2  
ENSEMBL proteins: 
 ENSP00000447512   ENSP00000450114   ENSP00000374614   ENSP00000447892   ENSP00000448642  
 ENSP00000450135  

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Protein Domains /
Families
for C14orf79 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q96F83


Function
for C14orf79 gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
Phenotypes:
     1 GenomeRNAi human phenotype for C14orf79:
 Decreased viability with pacli 

Animal Models:
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miRNA
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Inhib. RNA
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In Situ Assay
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Pathways & Interactions
for C14orf79 gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C14orf79

Drugs & Compounds
for C14orf79 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
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Browse Tocris compounds for C14orf79
Search CenterWatch for drugs/clinical trials and news about C14orf79 / CN079 

Transcripts
for C14orf79 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section
REFSEQ mRNAs for C14orf79 gene: 
NM_174891.3  

Unigene Cluster for C14orf79:

Chromosome 14 open reading frame 79
Hs.27183  [show with all ESTs]
Unigene Representative Sequence: NM_174891
9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000551606 ENST00000551046 ENST00000547315 ENST00000389964(uc001ypy.1 uc001ypz.1 uc010tym.1)
ENST00000548641 ENST00000549584 ENST00000550614 ENST00000549240 ENST00000548178


miRNA
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1 QIAGEN miScript miRNA Assays for microRNA that regulate C14orf79:
hsa-miR-29b-1*
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Inhib. RNA
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Clone
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Primer
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Additional cDNA sequence: 

AF038188.1 BC003539.1 BC011537.1 BC137495.1 BC144671.1 

11 DOTS entries:

DT.91759734  DT.213530  DT.75102179  DT.95223653  DT.120753617  DT.455026  DT.95268616  DT.95280142 
DT.100669831  DT.100779284  DT.91759736 

24/88 AceView cDNA sequences (see all 88):

Z38785 BU634462 BC011537 BG761097 BX442322 AF038188 BC003539 AA158771 
NM_174891 AW005124 AI697173 BE615724 AW510716 AI191646 BC025175 AI969050 
BU741353 CA309361 BM983171 BG749901 AI884614 CA390857 BM906801 BG250104 

GeneLoc Exon Structure


Expression
for C14orf79 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

C14orf79 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGGTGTACA
C14orf79 Expression
About this image

C14orf79 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

Stem Cell Differentiation: 1 LifeMap Cell 
NameCategory
Posterior foregut-like cells (A scalable, suspensi...)
Expression: Positive    Negative     Selective marker
Experimental details: Curated     Microarrays     In-situ hybridization

See C14orf79 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C14orf79

SOURCE GeneReport for Unigene cluster: Hs.27183
    SABiosciences Custom PCR Arrays for C14orf79
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In Situ
Assay Products: 
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Orthologs
for C14orf79 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
This gene was present in the common ancestor of chordates.

Orthologs for C14orf79 gene from 3/9 species (see all 9)    About this table
Organism Taxonomic
classification		 Gene Description Human
Similarity		 Orthology
Type		 Details
mouse
(Mus musculus)		 Mammalia BC0226871 , 5 cDNA sequence BC0226871, 5 72.2(n)1
59.56(a)1		   12 (61.20 cM)5
2178871  NM_145450.31  NP_663425.21 
 1128089755 
chicken
(Gallus gallus)		 Aves C5H14orf791 chromosome 5 open reading frame, human C14orf79 53.47(n)
37.14(a)		   423498  XM_421401.3  XP_421401.2 
lizard
(Anolis carolinensis)		 Reptilia C14orf796
 --
 38(a)
 1 ↔ 1
 1(3618459-3629181)


ENSEMBL Gene Tree for C14orf79 (if available)
TreeFam Gene Tree for C14orf79 (if available) 

Paralogs
for C14orf79 gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

Genomic Variants
for C14orf79 gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/224 NCBI SNPs in C14orf79 are shown (see all 224)     About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance		Chr 14 posSequence#AA
Chg		TypeMore#Allele
freq		PopTotal
sample		More
----------
rs1488811961,2
--105450624(+) AGGACA/GTGCAG 1 -- us2k10--------
rs1392373471,2
C--105450730(+) CCTTA-/GGGTCA 1 -- us2k10--------
rs1909832011,2
--105450774(+) TCCTGG/TGCAGT 1 -- us2k10--------
rs1380173251,2
--105450776(+) CTGGGC/GAGTCT 1 -- us2k10--------
rs1148868521,2
C--105450825(+) GCCCCG/TCAGGA 1 -- us2k10--------
rs1837054881,2
--105451056(+) ACCAGA/GGCCAG 1 -- us2k10--------
rs1458132481,2
--105451142(+) ACTCCC/TTGAGT 1 -- us2k10--------
rs1481934641,2
--105451216(+) TAGCTC/TCTTGG 1 -- us2k10--------
rs1181036331,2
F--105451362(+) GGGACG/TAGTTA 1 -- us2k11Minor allele frequency- T:0.02EA 120
rs1143382271,2
F--105451457(+) GCTCAG/ACTGCA 1 -- us2k11Minor allele frequency- A:0.04WA 118

HapMap Linkage Disequilibrium report for C14orf79 (105452112 - 105476819 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for C14orf79: --

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Disorders / Diseases
for C14orf79 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
   --

Publications
for C14orf79 gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for C14orf79 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C14orf79)		    Utopia: connect your pdf to the dynamic
world of online information

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  2. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (2003)
  3. Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia. (PubMed id 16112646)1 Guinn B.-A.... Mufti G.J. (2005)
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  6. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1 Yu W.... Gibbs R.A. (1997)
  7. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1 Andersson B.... Gibbs R.A. (1996)

External Searches for C14orf79 gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing C14orf79 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 122616 HGNC: 20126 AceView: C14orf79 Ensembl:ENSG00000140104 euGenes: HUgn122616
ECgene: C14orf79 H-InvDB: C14orf79

Other Databases showing C14orf79 gene

(According to HUGE)
About This Section
   --

Specialized Databases showing C14orf79 gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for C14orf79 Pharmacogenomics, SNPs, Pathways

Intellectual Property
for C14orf79 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for C14orf79 gene:
Search GeneIP for patents involving C14orf79

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
for C14orf79 gene

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About This Section

 
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VWF
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